apollo

Online Doctor Consultation & Medicines

Hello,

Select your location

0

Special offers

  1. Home

  2. CILANEM INJECTION 1GM

CILANEM INJECTION 1GM, Pack of 1 INJECTION

CILANEM INJECTION 1GM

Manufacturer/Marketer

RANBAXY LABORATORIES LTD

Composition

CILASTATIN-500MG + IMIPENEM-500MG

Consume Type

PARENTERAL

In Stock

Prescription Required
Product Details

About CILANEM INJECTION 1GM

CILANEM INJECTION 1GM is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach and female reproductive organs. CILANEM INJECTION 1GM may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. CILANEM INJECTION 1GM does not work against infections caused by the virus, including cold and flu. 
 
CILANEM INJECTION 1GM is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, CILANEM INJECTION 1GM helps to treat bacterial infections.
 
CILANEM INJECTION 1GM will be administered by a healthcare professional; do not self-administer. In some cases, CILANEM INJECTION 1GM may cause common side effects such as nausea, vomiting, diarrhoea, swelling, and redness at the site of injection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. CILANEM INJECTION 1GM may cause dizziness, so drive with caution. Avoid alcohol consumption as it might cause increased dizziness and sleepiness. CILANEM INJECTION 1GM should not be given to children below one year or those who weigh below 30kg with kidney problems. CILANEM INJECTION 1GM is not recommended in paediatric patients with CNS infections due to the risk of seizures. Keep your doctor informed about your health condition and medications to rule out any unpleasant side effects.

Uses of CILANEM INJECTION 1GM

Severe bacterial infections

Medicinal Benefits

CILANEM INJECTION 1GM is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). CILANEM INJECTION 1GM is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach, and female reproductive organs. CILANEM INJECTION 1GM may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, CILANEM INJECTION 1GM helps to treat bacterial infections. Imipenem is a broad-spectrum antibiotic that is effective against a wide range of aerobic and anaerobic bacteria.

Directions for Use

CILANEM INJECTION 1GM will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CILANEM INJECTION 1GM

  • Nausea
  • Vomiting
  • Diarrhoea
  • Swelling
  • Redness at the site of injection

In-Depth Precautions and Warning

Drug Warnings

Do not take CILANEM INJECTION 1GM if you are allergic to any of its components. Inform your doctor if you have an allergy to antibiotics, colitis, gastrointestinal disease, urinary/kidney problems, CNS disorders, seizures/fits, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption as it might cause increased dizziness and sleepiness. CILANEM INJECTION 1GM should not be given to children below one year or those who weigh below 30kg with kidney problems. CILANEM INJECTION 1GM is not recommended in paediatric patients with CNS infections due to the risk of seizures. CILANEM INJECTION 1GM may cause dizziness and sleepiness, so drive with caution.

Drug Interactions

Drug-Drug Interactions: CILANEM INJECTION 1GM may interact with anti-viral (Ganciclovir), uricosurics (Probenecid), anti-epileptic (Valproic acid, Divalproex sodium), blood thinner (warfarin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), CNS disorders, hemodialysis, kidney or liver dysfunction.

Drug-Drug Interactions Checker List:

  • GANCICLOVIR
  • PROBENECID
  • VALPROIC ACID
  • DIVALPROEX SODIUM
  • WARFARIN

    • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid alcohol consumption as it might cause increased dizziness and sleepiness.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe CILANEM INJECTION 1GM only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      CILANEM INJECTION 1GM may pass into breast milk. Please consult your doctor if you are breastfeeding; your doctor will decide if CILANEM INJECTION 1GM can be given to breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      CILANEM INJECTION 1GM may cause dizziness and sleepiness. Avoid driving or operating machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

    • Safety Warning

      Children

      caution

      CILANEM INJECTION 1GM should not be given to children below one year or those who weigh below 30kg with kidney problems. CILANEM INJECTION 1GM is not recommended in paediatric patients with CNS infections due to the risk of seizures.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, buttermilk, natto and cheese.
    • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
    • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
    • Avoid/limit the consumption of alcohol and usage of tobacco.

    Special Advise

    • CILANEM INJECTION 1GM may cause abnormal Coombs, liver, blood, and kidney function tests. Inform the person doing the tests that you are on treatment with CILANEM INJECTION 1GM. 

    Other Information (CIL0047)

    This item is Not Returnable.

    Expires on or after - Sep-23

    Patients Concern

    Disease/Condition Glossary

    Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Harmful bacteria produce chemicals known as toxins, which can damage tissue and cause sickness. Symptoms of bacterial infection include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.

    FAQs

    How does CILANEM INJECTION 1GM work?

    CILANEM INJECTION 1GM is a combination of two drugs, namely: Cilastatin and Imipenem. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, CILANEM INJECTION 1GM helps to treat bacterial infections.

    Does CILANEM INJECTION 1GM cause diarrhoea?

    Diarrhoea might be a side-effect of CILANEM INJECTION 1GM. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, consult your doctor. Do not take anti-diarrheal medicine on your own.

    Can I take Probenecid with CILANEM INJECTION 1GM?

    Concomitant administration of Probenecid (used to treat gout and hyperuricemia) along with CILANEM INJECTION 1GM is not recommended as it might result in an increase of plasma levels and half-life of Imipenem.

    Is it safe to take Ganciclovir along with CILANEM INJECTION 1GM?

    Ganciclovir (anti-viral) should not be co-administered along with CILANEM INJECTION 1GM unless benefits outweigh the risks as generalised seizures have been reported when taken together.

    Does CILANEM INJECTION 1GM cause discolouration of urine?

    CILANEM INJECTION 1GM may cause changes in urine colour and amount of urine. Do not worry and consult your doctor if you have any concerns regarding this.

    Does CILANEM INJECTION 1GM cause thrush?

    CILANEM INJECTION 1GM may rarely cause thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

    PRODUCT SUBSTITUTES

    CILANEM INJECTION 1GM

    Country Of Origin

    India

    Manufacturer/Marketer address

    SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063

    Disclaimer

    While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

    (Inclusive of all taxes)

    Provide Delivery Location

    Vial

    1

    1 Injection in 1 Vial