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compositionComposition:CINACALCET-30MG
prescription
Prescription Medicine
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Cinatreat Tablet is used to treat primary hyperparathyroidism, secondary hyperparathyroidism, and parathyroid cancer. It contains Cinacalcet, which works by signalling the body to produce less parathyroid hormone. In some cases, this medicine may cause side effects such as vomiting, nausea, rash, headache, muscle pain, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CINACALCET-30MG

Manufacturer/Marketer :

Genix Lifescience Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Cinatreat Tablet

Cinatreat Tablet is an oral prescription medicine used to lower high levels of parathyroid hormone in people with long-term kidney disease who are on dialysis. It is also used to reduce high calcium levels in the blood for people with parathyroid gland tumours or overactive parathyroid glands who cannot have surgery. By keeping these hormone and mineral levels in balance, it helps protect your bones and blood vessels from damage.

You should take Cinatreat Tablet consistently every day, exactly as your doctor directs. It is best to take this medicine with food or shortly after eating a meal, as this helps your body absorb the medicine properly. Alongside this treatment, your doctor may recommend specific dietary adjustments, such as limiting foods high in phosphorus or managing your calcium intake, to help you get the best results.

While taking Cinatreat Tablet , you may experience common mild side effects like nausea or vomiting. However, it is vital to contact your doctor immediately if you experience signs of low blood calcium, such as muscle spasms, numbness, tingling around your mouth, or a fast, pounding heartbeat. Always consult your doctor if you experience any persistent or severe side effects during your treatment.

Before starting Cinatreat Tablet , tell your doctor if you have a history of seizures, heart failure, liver problems, or abnormal heart rhythms. Do not take this if you already have low calcium levels in your blood, as this medicine will lower them further and could cause serious health complications.

This medicine can interact with other drugs, particularly certain heart medicines or antidepressants, which can alter how your body processes them. Additionally, smoking can speed up how quickly your body clears this medicine, potentially making it less effective. If you are pregnant, breastfeeding, or planning a family, talk to your doctor or pharmacist to carefully weigh the risks and benefits before starting treatment.

Uses of Cinatreat Tablet

Cinatreat Tablet is used in the treatment of hyperparathyroidism and parathyroid cancer. The detailed uses of Cinatreat Tablet are as follows:

  • Primary hyperparathyroidism: Cinatreat Tablet lowers elevated blood calcium levels in people who have overactive parathyroid glands but are unable to have surgery to remove them.
  • Secondary hyperparathyroidism in chronic kidney disease: Cinatreat Tablet helps control overactive parathyroid glands in patients on dialysis, lowering parathyroid hormone, calcium, and phosphorus to protect bone health.
  • Parathyroid carcinoma: Cinatreat Tablet reduces dangerously high levels of calcium in the blood for individuals with this rare type of parathyroid cancer.

Key Benefits

Cinatreat Tablet helps lower high parathyroid hormone levels in people with chronic kidney disease or certain parathyroid disorders, supporting healthier bones and mineral balance.

The following are the benefits of Cinatreat Tablet :

  • Helps prevent calcium from being removed from your bones, reducing bone pain and lowering the risk of fractures.
  • Keeps calcium and phosphorus levels in a healthy range, reducing mineral buildup in your blood vessels and heart and helping protect your cardiovascular health.
  • Supports long-term health during dialysis by controlling parathyroid hormone and mineral levels, helping reduce complications associated with chronic kidney disease.
Side effects of Cinatreat Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
Managing Medication-Triggered Hypocalcemia (Calcium deficiency or Low Calcium Levels In Blood): A Step-by-Step Guide:
  • Consult Your Doctor: If you experience symptoms such as muscle cramps, tingling, numbness, weakness, or spasms, which may indicate low calcium levels (hypocalcemia), consult your doctor to determine if your medication is the cause.
  • Your doctor will assess your medication regimen and adjust it if necessary to minimize the risk of hypocalcemia.
  • Your doctor may order blood tests to check your calcium levels and monitor for any changes.
  • To manage hypocalcemia, your doctor recommends dietary and lifestyle modifications. This may include increasing your intake of calcium-rich foods to support bone health and calcium levels. If necessary, your doctor may also prescribe calcium and vitamin D supplements to help stabilize your calcium levels.
  • If your condition does not improve or worsens, consult your doctor immediately for further evaluation and treatment.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • Cinatreat Tablet should be taken with food or shortly after a meal.
  • It is usually taken 1-2 times daily, depending on the medical condition or as prescribed by a doctor.
  • Swallow Cinatreat Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Cinatreat Tablet Works

To understand how Cinatreat Tablet works, it helps to look at your parathyroid glands, which are tiny glands in your neck. These glands release parathyroid hormone to control the amount of calcium in your blood. When you have kidney disease or overactive glands, they mistakenly think your body needs more calcium, so they constantly release too much hormone. Cinatreat Tablet works by mimicking the action of calcium on the sensors of these glands. This fools the parathyroid glands into thinking there is already plenty of calcium in your blood. As a result, the glands slow down their hormone production, which in turn lowers the levels of both calcium and phosphorus circulating in your body.
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Alcohol

Caution

Cinatreat Tablet with alcohol may cause unpleasant effects. So please consult your doctor before taking Cinatreat Tablet with alcohol.

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Pregnancy

Caution

Cinatreat Tablet is not recommended for use in pregnant women unless necessary. Before taking this medicine, the risks and benefits should be discussed with the doctor.

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Breast Feeding

Caution

Cinatreat Tablet is not recommended for use in breastfeeding women unless necessary. Before taking this medicine, the risks and benefits should be discussed with the doctor. Your doctor may advise you to discontinue the medicine or breastfeeding based on your clinical condition.

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Driving

Caution

Cinatreat Tablet may cause blurred vision, dizziness, and drowsiness in some patients. You are advised not to perform any activities, such as driving a vehicle or operating machinery, if you experience any of these symptoms during treatment with this medicine.

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Liver

Caution

Cinatreat Tablet should be used with caution in patients with liver disease. A dose adjustment of Cinatreat Tablet may be needed in some cases. So, please consult your doctor.

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Kidney

Caution

Cinatreat Tablet is not recommended for use in patients suffering from chronic kidney disease who are not being treated with dialysis due to the increased risk of hypocalcemia (low blood calcium levels). Depending on your clinical condition, dose adjustments or replacement with a suitable alternative drug should be considered.

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Children

Caution

Cinatreat Tablet should not be used in children below 12 years of age unless prescribed by a doctor.

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Heart

Safe if prescribed

Cinatreat Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Safe if prescribed

Cinatreat Tablet is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Cinatreat Tablet

If you accidentally take too much of this medicine, seek emergency medical attention or contact a poison control centre immediately. An overdose can cause dangerously low calcium levels, which can lead to serious heart and muscle complications.

Diet & Lifestyle Advise

  • Monitor your calcium intake: Speak with your dietitian or doctor before taking any calcium supplements, antacids containing calcium, or eating large amounts of dairy, as your calcium levels need to be closely regulated.
  • Follow a low-phosphorus diet: If you are on dialysis, limit foods high in phosphorus (such as nuts, seeds, dark colas, and processed foods) to help Cinatreat Tablet manage your mineral levels more effectively.
  • Stay hydrated: If you have high calcium levels due to parathyroid cancer or primary hyperparathyroidism, drink plenty of fluids as directed by your doctor to help your kidneys flush out excess calcium.
  • Attend all blood test appointments: Regular blood tests are essential to measure your calcium, phosphorus, and parathyroid hormone levels, allowing your doctor to keep your treatment safe and effective.
health query

Have a query?

How Soon It Starts Working

The time required for Cinatreat Tablet to start to work: Cinatreat Tablet ideally shows its action within 2 to 6 hours after administration.

The time for which the effects of Cinatreat Tablet last: The effect of Cinatreat Tablet lasts for 30 to 40 hours.

What if you forget to take Cinatreat Tablet

If you miss a dose of Cinatreat Tablet , skip the missed dose and take your next scheduled dose at your usual time. Do not take a double dose to make up for a forgotten one.

Storage

•Store Cinatreat Tablet tablets at controlled room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Know the warning signs of low calcium: Before starting, make sure you and your family can recognise the signs of low blood calcium, such as tingling fingers, muscle cramps, or twitching, and seek help immediately if they occur.
  • Check your heart health: Let your doctor know if you have an irregular heart rhythm, as low calcium levels can worsen this condition.
  • Monitor for stomach bleeding: If you have a history of stomach ulcers or gastrointestinal bleeding, inform your doctor immediately if you notice black, tarry stools or vomit that looks like coffee grounds.
  • Do not share your medicine: This prescription is strictly individualised based on your specific blood chemistry and should never be shared with others.

Drug-Drug Interactions

verifiedApollotooltip
  • Medicines metabolised by the CYP2D6 enzyme (e.g., metoprolol for blood pressure, flecainide for heart rhythm, amitriptyline for depression): Cinatreat Tablet can increase the levels of these drugs in your body and raise the risk of side effects. Your doctor may need to adjust their doses.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): Certain antifungals and antibiotics can slow down how your body breaks down Cinatreat Tablet , potentially raising its levels and increasing the risk of side effects.
CinacalcetThioridazine
Critical
CinacalcetPimozide
Critical

Drug-Drug Interactions

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CinacalcetThioridazine
Critical
How does the drug interact with Cinatreat Tablet:
When Thioridazine and Cinatreat Tablet are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Cinatreat Tablet with Thioridazine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CinacalcetPimozide
Critical
How does the drug interact with Cinatreat Tablet:
When Pimozide and Cinatreat Tablet are taken together, the risk or severity of side effects may be increased including an abnormal heart rhythm.

How to manage the interaction:
Taking Cinatreat Tablet with Pimozide is not recommended as it can lead to an interaction, but can be taken if prescribed by the doctor. However, if you experience muscle pains or uncontrolled movements, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, eye blinking, eye rolling, shaking or jerking of arms and legs, jitteriness, restlessness, and foot tapping, sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor.
CinacalcetTamoxifen
Severe
How does the drug interact with Cinatreat Tablet:
Taking Cinatreat Tablet and Tamoxifen together for longer duration might decrease the effectiveness of Tamoxifen in treating breast cancer.

How to manage the interaction:
Taking Cinatreat Tablet and Tamoxifen together can result in an interaction, it can be taken if your doctor has advised it. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without a doctor's advice.
CinacalcetIloperidone
Severe
How does the drug interact with Cinatreat Tablet:
Taking Cinatreat Tablet and Iloperidone together may greatly increase the levels of Iloperidone, which may increase the risk of side effects.

How to manage the interaction:
Taking Cinatreat Tablet and Iloperidone together can result in an interaction, it can be taken if your doctor has advised it. If you experience symptoms like -fainting, increased heart rate, convulsions(fits), uncontrollable movements, shaking or jerking of the hands and legs, consult a doctor. Be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
CinacalcetBrexpiprazole
Severe
How does the drug interact with Cinatreat Tablet:
Taking Cinatreat Tablet and Brexpiprazole may increase the levels of Brexpiprazole, which increases the risk of side effects.

How to manage the interaction:
Taking Cinatreat Tablet and Brexpiprazole together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like an increased heart rate, convulsions(fits), muscles pains, or uncontrollable movements like shaking, foot tapping, teeth tightening, jaw shaking, eye rolling, or shaking or jerking of the hands and legs you need to consult a doctor. Do not discontinue any medications without consulting a doctor.
CinacalcetClarithromycin
Severe
How does the drug interact with Cinatreat Tablet:
Co-administration of Cinatreat Tablet with Clarithromycin can increase the levels of Cinatreat Tablet, which may increase the risk of side effects.

How to manage the interaction:
Taking Cinatreat Tablet and Clarithromycin together can result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
CinacalcetAtomoxetine
Severe
How does the drug interact with Cinatreat Tablet:
Taking Atomoxetine and Cinatreat Tablet together can significantly increase the blood levels of Atomoxetine, which may increase the risk of side effects.

How to manage the interaction:
Taking Atomoxetine and Cinatreat Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like dizziness, dry mouth, decreased hunger, sleep disturbances, and heart palpitations, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Taking with food: Eating a meal or taking this medicine shortly after food significantly increases how much of the drug your body absorbs, helping it work more consistently.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[BONE ENHANCERS]

FAQs

Cinatreat Tablet is used to treat primary hyperparathyroidism, secondary hyperparathyroidism, and parathyroid carcinoma.
Cinatreat Tablet works by signalling the body to produce less parathyroid hormone to decrease the amount of calcium in the blood.
Cinatreat Tablet is not recommended for use in patients suffering from chronic kidney disease who are not being treated with dialysis due to the increased risk of hypocalcemia (low blood calcium levels). Replacement with a suitable alternative should be considered based on the clinical condition.
If you have hypotension (low blood pressure) and hypocalcemia (low calcium levels in the blood), please contact a doctor before taking Cinatreat Tablet .
Cinatreat Tablet should be used with extreme caution in patients suffering from seizures due to the increased risk of worsening their condition. Please consult your doctor before taking Cinatreat Tablet .
Cinatreat Tablet may cause diarrhoea. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the diarrhoea persists or worsens.
Sometimes lactose is used in medicines. Inform the doctor if you have sugar/lactose intolerance. Check the label to know if Cinatreat Tablet contains lactose.
Cinatreat Tablet may cause common side effects like vomiting, nausea, rash, headache, muscle pain, and diarrhoea. If the side effects persist or worsen, consult a doctor.
Take Cinatreat Tablet exactly as prescribed by your doctor. It should be taken with food or shortly after a meal, preferably at the same time each day. Taking it with food improves absorption and helps reduce stomach upset. Avoid taking it on an empty stomach. If you have difficulty following these instructions, consult your doctor or pharmacist.
Signs of low blood calcium include tingling or numbness around your mouth, fingers, or toes, muscle cramps, spasms, and, in severe cases, seizures. If you experience any of these symptoms, contact your doctor right away.
No, you should always swallow Cinatreat Tablet tablets whole. Do not crush, chew, split, or break them, as doing so can change how quickly the medicine is released into your system. Talk to your doctor or pharmacist if you have difficulty swallowing pills.
Yes, you will need frequent blood tests to monitor your calcium, phosphorus, and parathyroid hormone levels. These tests help your doctor ensure the medicine is working safely and determine if your dose needs to be adjusted. Talk to your doctor about your testing schedule.
There is limited research on the safety of Cinatreat Tablet during pregnancy or breastfeeding. You should discuss the potential risks and benefits with your healthcare provider before starting this medication. Talk to your doctor if you are pregnant or planning to become pregnant.
No, Cinatreat Tablet does not cure kidney disease. Instead, it helps manage one of the serious complications of long-term kidney disease by controlling your parathyroid hormone and mineral levels to protect your bones and blood vessels. Talk to your doctor to understand your overall treatment plan.
Nausea is a common side effect of Cinatreat Tablet , especially when you first start taking it. Taking your dose exactly with a meal can help reduce stomach upset. If the nausea is severe, persistent, or prevents you from eating, talk to your doctor or pharmacist.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 021688S017Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Cinacalcet Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Cinacalcet Cinacalcet. 2004. [Accessed on 04 Apr. 2019]Check here
  5. Cinacalcet [Prescribing Information]. 2021. [Accessed on 16 Jun. 2023]Check here
  6. WebMD. Cinacalcet. [[Accessed on 6 Sept].2019] :Check here
  7. Bharath M. Reddy, MD, Howard S. Weintraub, MD, and Arthur Z. Schwartzbard, MD, A New Approach to Treating an Old Problem. [Accessed on January 09th, 2024]Check here

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - CIN0286
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