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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Clarican 500mg Injection 10 ml is an antibiotic used in treating bacterial infections. It contains Clarithromycin, which stops the growth of bacteria. It may cause side effects like injection site reactions, nausea, and vomiting. Inform your doctor if you are pregnant, breasfeeding, taking any other medicines or have pre-existing medical conditions.

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Manufacturer/Marketer :

H & Care Incorp

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

About Clarican 500mg Injection 10 ml

Clarican 500mg Injection 10 ml belongs to the group of medicines known as macrolide antibiotics, used to treat infections caused by bacteria such as bronchitis, pneumonia, throat, sinus, skin and soft tissue infections. It is prescribed for treating severe infections or when oral therapy is ineffective.

Clarican 500mg Injection 10 ml contains 'Clarithromycin', which works by killing the bacteria that cause the infection by preventing the synthesis of essential proteins necessary for the survival of the bacteria. Thereby, it effectively treats bacterial infections.

You may experience injection site reactions (redness, swelling, and pain), headache, nausea or vomiting, stomach pain, and diarrhoea. Most of these side effects do not require medical attention and resolve over time. Please consult your doctor if these side effects become troublesome.

Inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby or if you are breastfeeding. Let your doctor know about your medical condition and the medications you are taking to avoid any interactions.

Uses of Clarican 500mg Injection 10 ml

Clarican 500mg Injection 10 ml is used to treat a wide range of bacterial infections. The detailed uses of Clarican 500mg Injection 10 ml include:

  • Treatment of respiratory tract infections: Clarican 500mg Injection 10 ml is effective in managing infections such as bronchitis, sinusitis, and pneumonia.
  • Treatment of throat and tonsil infections: Clarican 500mg Injection 10 ml helps relieve bacterial infections affecting the throat and tonsils, including pharyngitis and tonsillitis.
  • Treatment of skin and soft tissue infections: Clarican 500mg Injection 10 ml is used to treat conditions like cellulitis, infected wounds, and other skin infections caused by susceptible bacteria.
  • Treatment of ear infections: Clarican 500mg Injection 10 ml is sometimes used for bacterial middle ear infections in children and adults.
  • Part of combination therapy for Helicobacter pylori: Clarican 500mg Injection 10 ml may be used with other medicines to eradicate H. pylori, which is linked to peptic ulcers.

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Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Clarican 500mg Injection 10 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Key Benefits

  • Clarican 500mg Injection 10 ml belongs to the macrolide class of antibiotics. It is used to treat a wide range of bacterial infections.
  • It is effective in treating lower respiratory tract infections, such as acute and chronic bronchitis and pneumonia.
  • It also treats upper respiratory tract infections, including sinusitis and pharyngitis.
  • It helps manage skin and soft tissue infections such as folliculitis, erysipelas and cellulitis.
  • Clarican 500mg Injection 10 ml works by blocking bacterial protein synthesis, preventing bacteria from growing and multiplying.
  • It is useful in severe infections or when oral antibiotic therapy is ineffective.
  • Clarican 500mg Injection 10 ml helps eliminate infection and improve symptoms by killing the bacteria at the infection site.

How Clarican 500mg Injection 10 ml Works

Clarican 500mg Injection 10 ml contains 'Clarithromycin', which works by killing the bacteria that cause the infection by preventing the synthesis of essential proteins necessary for the survival of the bacteria. Thereby, it effectively treats bacterial infections.

Storage

Store in a cool and dry place away from sunlight
  • Drink plenty of fluids and consider oral rehydration solutions.
  • Eat bland, easily digestible foods like bananas, rice, toast, and applesauce.
  • Avoid trigger foods like greasy, spicy, fatty, acidic, and caffeinated foods.
  • Gradually reintroduce fiber-rich foods as symptoms improve.
  • Get adequate sleep and rest.
  • Practice relaxation techniques to manage stress.
  • Maintain regular bowel habits.
  • Avoid overexertion and take breaks when needed.
  • Consult a doctor if your gastrointestinal symptoms are severe, persistent, or accompanied by fever, bloody stools, dehydration, or last for more than a few days.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Clarican 500mg Injection 10 ml

Clarican 500mg Injection 10 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include agitation, confusion, coma (decreased level of consciousness and lack of responsiveness), and Seizures, in a very severe overdose. Dizziness, drowsiness, blurred vision, and delirium are the common symptoms of overdose. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

  • Do not take Clarican 500mg Injection 10 ml if you are allergic or hypersensitive to clarithromycin, any of the ingredients in Clarican 500mg Injection 10 ml, any other macrolide antibiotic, or ketolide (macrolide derivatives).
  • Consult your doctor if you are pregnant or breastfeeding.
  • Inform your doctor if you have/had hypokalemia (abnormally low levels of potassium in the blood), hypomagnesemia (abnormally low levels of magnesium in the blood), severe kidney or liver problems, heart rhythm disorders, heart problems, or are prone to fungal infections (e.g. thrush).
  • Let your doctor know if you are taking any other medicines.

Drug-Drug Interactions

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Drug-Drug Interactions

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Critical
How does the drug interact with Clarican 500mg Tablet 10 ml:
Co-administration of Bepridil with Clarican 500mg Tablet 10 ml may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Clarican 500mg Tablet 10 ml with Bepridil is not recommended as it can result in an interaction, it should be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clarican 500mg Tablet 10 ml:
When Cabergoline is taken with Clarican 500mg Tablet 10 ml, the amount of Cabergoline in the blood can go up.

How to manage the interaction:
Taking Cabergoline with Clarican 500mg Tablet 10 ml is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Clarican 500mg Tablet 10 ml:
Taking Rifabutin and Clarican 500mg Tablet 10 ml together may increase the blood levels of rifabutin.

How to manage the interaction:
Taking Rifabutin with Clarican 500mg Tablet 10 ml is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ClarithromycinErgotamine
Critical
How does the drug interact with Clarican 500mg Tablet 10 ml:
When Ergotamine is taken with Clarican 500mg Tablet 10 ml, the amount of Ergotamine in the blood can go up.

How to manage the interaction:
Taking Clarican 500mg Tablet 10 ml with Ergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinVenetoclax
Critical
How does the drug interact with Clarican 500mg Tablet 10 ml:
When Venetoclax is taken with Clarican 500mg Tablet 10 ml, the body's ability to break down Venetoclax may be reduced.

How to manage the interaction:
Taking Clarican 500mg Tablet 10 ml with Venetoclax is not recommended, please consult your doctor before taking it.
ClarithromycinFlibanserin
Critical
How does the drug interact with Clarican 500mg Tablet 10 ml:
When Flibanserin is taken with Clarican 500mg Tablet 10 ml, it can slow down the way Flibanserin is broken down in the body.

How to manage the interaction:
Co-administration of Clarican 500mg Tablet 10 ml and Flibanserin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinAstemizole
Critical
How does the drug interact with Clarican 500mg Tablet 10 ml:
When Astemizole is taken with Clarican 500mg Tablet 10 ml, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Clarican 500mg Tablet 10 ml with Astemizole is not recommended, please consult your doctor before taking it.
How does the drug interact with Clarican 500mg Tablet 10 ml:
The combination of Alprazolam and Clarican 500mg Tablet 10 ml may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Alprazolam and Clarican 500mg Tablet 10 ml, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clarican 500mg Tablet 10 ml:
Co-administration of Clarican 500mg Tablet 10 ml and Sparfloxacin may result in an increased risk of QT interval prolongation.

How to manage the interaction:
Co-administration of Sertraline and Desvenlafaxine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Clarican 500mg Tablet 10 ml:
Coadministration of colchicine with Clarican 500mg Tablet 10 ml may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicine with Clarican 500mg Tablet 10 ml is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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CLARITHROMYCIN-500MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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CLARITHROMYCIN-500MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice may delay the gastrointestinal absorption of Clarican 500mg Tablet 10 ml. Avoid grapefruit juice while on treatment with Clarican 500mg Tablet 10 ml.

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Clarican 500mg Injection 10 ml to restore healthy bacteria in the intestine that may have been killed due to the use of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should be included in the diet.
  • Avoid intake of alcoholic beverages with Clarican 500mg Injection 10 ml as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Clarican 500mg Injection 10 ml in fighting off infections.

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

All Substitutes & Brand Comparisons

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Alcohol

Safe if prescribed

It is advisable to avoid or limit alcohol intake.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

It is not known if Clarican 500mg Injection 10 ml passes into breastmilk. Please consult your doctor.

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Driving

Safe if prescribed

Clarican 500mg Injection 10 ml may cause dizziness, confusion, and loss of balance. Therefore avoid driving or operating machinery if you experience any of these symptoms.

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Liver

Consult your doctor

Caution is advised. If you have/had liver problems, your doctor may need to monitor your liver function or discontinue treatment.

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Kidney

Consult your doctor

Consult your doctor if you have kidney problems, as your doctor may need to adjust the dose.

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Children

Safe if prescribed

Clarican 500mg Injection 10 ml is not recommended for children as safety and effectiveness have not been established.

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Heart

Inform your doctor before receiving Clarican 500mg Injection 10 ml if you have a pre-existing or a history of heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Clarican 500mg Injection 10 ml should be used in the elderly only if advised by a doctor, as dose adjustment may be required.

FAQs

Clarican 500mg Injection 10 ml belongs to the group of medicines known as macrolide antibiotics, used to treat infections caused by bacteria such as bronchitis, pneumonia, throat, sinus, skin and soft tissue infections.

Clarican 500mg Injection 10 ml kills the harmful bacteria by preventing the production of proteins required by the bacteria for their survival.

Using Clarican 500mg Injection 10 ml together with statins (medicines used to lower cholesterol levels) is not advisable. Please notify your doctor if you must take these medications. Your doctor may advise you to maintain a time gap between these two medications.

Clarican 500mg Injection 10 ml can cause Clostridium difficile-associated diarrhoea (CDAD). If you have diarrhoea that is watery or bloody, inform your doctor. Do not use anti-diarrhoea medicine unless your doctor tells you to.

You should inform your doctor before taking Clarican 500mg Injection 10 ml if you have liver or kidney dysfunction, heart rhythm disorder (arrhythmia) or QT prolongation, electrolyte imbalance (low potassium or magnesium level), or muscle problems (myasthenia gravis).

Clarican 500mg Injection 10 ml should not be taken with any ergot derivatives such as ergotamine or dihydroergotamine, used to treat migraine. Consult your doctor if you have any concerns.

Prolonged use of Clarican 500mg Injection 10 ml can result in a yeast infection or oral thrush. Look out for symptoms like white patches in the mouth or changes in vaginal discharge.

Country of origin

INDIA

Manufacturer/Marketer address

Plot no 286, Industrial Area Phase 1, Panchkula, Haryana 134113
Other Info - CLA0814

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