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  1. Home
  2. Medicine

  3. Crixan 500Mg Inj

Prescription drug
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Crixan 500Mg Inj, Pack of 1 Injection
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Extra 15% Off with Bank Offers

Composition :

CLARITHROMYCIN-500MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Crixan 500Mg Inj

Crixan 500Mg Inj belongs to the group of medicines known as macrolide antibiotics, used to treat infections caused by bacteria such as bronchitis, pneumonia, throat, sinus, skin and soft tissue infections. It is prescribed for treating severe infections or when oral therapy is ineffective.

Crixan 500Mg Inj contains 'Clarithromycin', which works by killing the bacteria that cause the infection by preventing the synthesis of essential proteins necessary for the survival of the bacteria. Thereby, it effectively treats bacterial infections.

You may experience injection site reactions (redness, swelling, and pain), headache, nausea or vomiting, stomach pain, and diarrhoea. Most of these side effects do not require medical attention and resolve over time. Please consult your doctor if these side effects become troublesome.

Inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby or if you are breastfeeding. Let your doctor know about your medical condition and the medications you are taking to avoid any interactions.

Uses of Crixan 500Mg Inj

Crixan 500Mg Inj is used to treat a wide range of bacterial infections. The detailed uses of Crixan 500Mg Inj include:

  • Treatment of respiratory tract infections: Crixan 500Mg Inj is effective in managing infections such as bronchitis, sinusitis, and pneumonia.
  • Treatment of throat and tonsil infections: Crixan 500Mg Inj helps relieve bacterial infections affecting the throat and tonsils, including pharyngitis and tonsillitis.
  • Treatment of skin and soft tissue infections: Crixan 500Mg Inj is used to treat conditions like cellulitis, infected wounds, and other skin infections caused by susceptible bacteria.
  • Treatment of ear infections: Crixan 500Mg Inj is sometimes used for bacterial middle ear infections in children and adults.
  • Part of combination therapy for Helicobacter pylori: Crixan 500Mg Inj may be used with other medicines to eradicate H. pylori, which is linked to peptic ulcers.

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Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Crixan 500Mg Inj will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Medicinal Benefits

  • Crixan 500Mg Inj belongs to the macrolide class of antibiotics. It is used to treat a wide range of bacterial infections.
  • It is effective in treating lower respiratory tract infections, such as acute and chronic bronchitis and pneumonia.
  • It also treats upper respiratory tract infections, including sinusitis and pharyngitis.
  • It helps manage skin and soft tissue infections such as folliculitis, erysipelas and cellulitis.
  • Crixan 500Mg Inj works by blocking bacterial protein synthesis, preventing bacteria from growing and multiplying.
  • It is useful in severe infections or when oral antibiotic therapy is ineffective.
  • Crixan 500Mg Inj helps eliminate infection and improve symptoms by killing the bacteria at the infection site.

How Crixan 500Mg Inj Works

Crixan 500Mg Inj contains 'Clarithromycin', which works by killing the bacteria that cause the infection by preventing the synthesis of essential proteins necessary for the survival of the bacteria. Thereby, it effectively treats bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Crixan 500Mg Inj
  • Use a warm compress on the affected area to help reduce discomfort.
  • Elevate the affected limb above heart level.
  • Remove the IV catheter (if applicable) and reinsert at a different site.
  • Consult your healthcare provider if symptoms are severe or persist.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Crixan 500Mg Inj

Crixan 500Mg Inj is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include agitation, confusion, coma (decreased level of consciousness and lack of responsiveness), and Seizures, in a very severe overdose. Dizziness, drowsiness, blurred vision, and delirium are the common symptoms of overdose. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

  • Do not take Crixan 500Mg Inj if you are allergic or hypersensitive to clarithromycin, any of the ingredients in Crixan 500Mg Inj, any other macrolide antibiotic, or ketolide (macrolide derivatives).
  • Consult your doctor if you are pregnant or breastfeeding.
  • Inform your doctor if you have/had hypokalemia (abnormally low levels of potassium in the blood), hypomagnesemia (abnormally low levels of magnesium in the blood), severe kidney or liver problems, heart rhythm disorders, heart problems, or are prone to fungal infections (e.g. thrush).
  • Let your doctor know if you are taking any other medicines.

Drug-Drug Interactions

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ClarithromycinAstemizole
Critical
ClarithromycinAlprazolam
Critical

Drug-Drug Interactions

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ClarithromycinAstemizole
Critical
How does the drug interact with Crixan 500Mg Inj:
When Astemizole is taken with Crixan 500Mg Inj, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Crixan 500Mg Inj with Astemizole is not recommended, please consult your doctor before taking it.
ClarithromycinAlprazolam
Critical
How does the drug interact with Crixan 500Mg Inj:
The combination of Alprazolam and Crixan 500Mg Inj may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Alprazolam and Crixan 500Mg Inj, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.
ClarithromycinLomitapide
Critical
How does the drug interact with Crixan 500Mg Inj:
When Lomitapide is taken with Crixan 500Mg Inj, it can lower the metabolism of Lomitapide.

How to manage the interaction:
Co-administration of Crixan 500Mg Inj and Lomitapide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, and liver damage, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinRanolazine
Critical
How does the drug interact with Crixan 500Mg Inj:
When Ranolazine and Crixan 500Mg Inj are taken together, significantly increases the blood levels and effects of Ranolazine.

How to manage the interaction:
Co-administration of Crixan 500Mg Inj and Ranozaline can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
ClarithromycinCabergoline
Critical
How does the drug interact with Crixan 500Mg Inj:
When Cabergoline is taken with Crixan 500Mg Inj, the amount of Cabergoline in the blood can go up.

How to manage the interaction:
Taking Cabergoline with Crixan 500Mg Inj is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
ClarithromycinConivaptan
Critical
How does the drug interact with Crixan 500Mg Inj:
When Crixan 500Mg Inj is taken with Conivaptan, it can lower the rate at which Conivaptan is broken down in the body.

How to manage the interaction:
Taking Crixan 500Mg Inj with Convivaptan can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinMethylergometrine
Critical
How does the drug interact with Crixan 500Mg Inj:
When Methylergometrine is taken with Crixan 500Mg Inj, the amount of Methylergometrine in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Crixan 500Mg Inj with Methylergometrine is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
ClarithromycinLovastatin
Critical
How does the drug interact with Crixan 500Mg Inj:
Taking Crixan 500Mg Inj with Lovastatin can increase the risk of muscle problems.

How to manage the interaction:
Co-administration of Crixan 500Mg Inj and Lovastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinSimvastatin
Critical
How does the drug interact with Crixan 500Mg Inj:
Co-administration of Crixan 500Mg Inj and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Crixan 500Mg Inj and Simvastatin together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
ClarithromycinEplerenone
Critical
How does the drug interact with Crixan 500Mg Inj:
Co-administration of Eplerenone and Crixan 500Mg Inj may significantly increase the blood levels and effects of eplerenone.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Crixan 500Mg Inj with Eplerenone is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Crixan 500Mg Inj to restore healthy bacteria in the intestine that may have been killed due to the use of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should be included in the diet.
  • Avoid intake of alcoholic beverages with Crixan 500Mg Inj as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Crixan 500Mg Inj in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Crixan 500Mg Inj Substitute

Substitutes safety advice
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Alcohol

Caution

It is advisable to avoid or limit alcohol intake.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

It is not known if Crixan 500Mg Inj passes into breastmilk. Please consult your doctor.

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Driving

Caution

Crixan 500Mg Inj may cause dizziness, confusion, and loss of balance. Therefore avoid driving or operating machinery if you experience any of these symptoms.

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Liver

Caution

Caution is advised. If you have/had liver problems, your doctor may need to monitor your liver function or discontinue treatment.

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Kidney

Caution

Consult your doctor if you have kidney problems, as your doctor may need to adjust the dose.

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Children

Caution

Crixan 500Mg Inj is not recommended for children as safety and effectiveness have not been established.

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Heart

Inform your doctor before receiving Crixan 500Mg Inj if you have a pre-existing or a history of heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Crixan 500Mg Inj should be used in the elderly only if advised by a doctor, as dose adjustment may be required.

FAQs

Crixan 500Mg Inj belongs to the group of medicines known as macrolide antibiotics, used to treat infections caused by bacteria such as bronchitis, pneumonia, throat, sinus, skin and soft tissue infections.

Crixan 500Mg Inj kills the harmful bacteria by preventing the production of proteins required by the bacteria for their survival.

Using Crixan 500Mg Inj together with statins (medicines used to lower cholesterol levels) is not advisable. Please notify your doctor if you must take these medications. Your doctor may advise you to maintain a time gap between these two medications.

Crixan 500Mg Inj can cause Clostridium difficile-associated diarrhoea (CDAD). If you have diarrhoea that is watery or bloody, inform your doctor. Do not use anti-diarrhoea medicine unless your doctor tells you to.

You should inform your doctor before taking Crixan 500Mg Inj if you have liver or kidney dysfunction, heart rhythm disorder (arrhythmia) or QT prolongation, electrolyte imbalance (low potassium or magnesium level), or muscle problems (myasthenia gravis).

Crixan 500Mg Inj should not be taken with any ergot derivatives such as ergotamine or dihydroergotamine, used to treat migraine. Consult your doctor if you have any concerns.

Prolonged use of Crixan 500Mg Inj can result in a yeast infection or oral thrush. Look out for symptoms like white patches in the mouth or changes in vaginal discharge.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - CRI0097

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Oct 22, 2025 | 12:57 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.8825.pdf
  2. https://www.medicines.org.uk/emc/product/8825/smpc
  3. https://www.drugs.com/drug-interactions/clarithromycin.html

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