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compositionComposition:CLOMIFENE CITRATE-25MG
prescription
Prescription Medicine
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Clo-Mature-25 Tablet 10's belongs to the group of medications called ovulation stimulants used in the treatment of female infertility. This medicine helps boosts the production of hormones involved in the ovulation process. Common side effects include flushing (reddening of the skin, especially the face), headache, tiredness, dizziness, breast pain or tenderness, heavy periods, bleeding between periods, etc. This medicine is only intended for use in women. Hence should not be used in the male population, pregnant/breastfeeding women, and children.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

CLOMIFENE CITRATE-25MG

Manufacturer/Marketer :

Drus Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-29

Return Policy :

Not Returnable

About Clo-Mature-25 Tablet 10's

Clo-Mature-25 Tablet 10's is a prescription medication used to treat female infertility, specifically in women who have trouble ovulating. It works by stimulating the ovaries to produce and release mature eggs, helping to increase the chances of conception. This medicine is typically prescribed for women who have irregular cycles or conditions like polycystic ovary syndrome (PCOS).

To achieve the best results, you must take Clo-Mature-25 Tablet 10's consistently at the same time each day for a brief 5-day cycle as directed by your doctor. You can take this tablet with or without food, but keeping a regular schedule helps maintain steady hormone levels. Combining this treatment with lifestyle adjustments, such as tracking your body temperature and managing stress, can support your body during the cycle.

While taking Clo-Mature-25 Tablet 10's, some women experience mild, temporary side effects like hot flashes, stomach bloating, or breast tenderness. If you experience any severe symptoms, such as sudden vision changes, severe pelvic pain, or rapid weight gain, stop taking the medicine and seek medical attention immediately.

Before you begin taking this medicine, talk to your doctor if you have a history of liver problems, unusual vaginal bleeding, thyroid issues, or ovarian cysts. Do not take this medicine if you are already pregnant, have active liver damage, or experience unexplained bleeding from your uterus.

It is important to inform your healthcare provider of all other medications you take, as some fertility drugs or hormonal therapies can interact with Clo-Mature-25 Tablet 10's. Avoid drinking alcohol while using this medicine, as it can worsen side effects like dizziness and hot flashes. This medication is not intended for use in pregnant or breastfeeding women, or in elderly individuals.

Uses of Clo-Mature-25 Tablet 10's

Clo-Mature-25 Tablet 10's is used to stimulate ovulation and improve the chances of conception in women with certain ovulation-related fertility problems, including:

  • Female infertility due to ovulatory dysfunction: Clo-Mature-25 Tablet 10's helps women who do not release eggs regularly, or at all, by stimulating the ovaries to develop and release mature eggs for fertilization.
  • Polycystic Ovary Syndrome (PCOS): It supports regular ovulation cycles in women diagnosed with PCOS who are trying to conceive.

Key Benefits

The benefits of Clo-Mature-25 Tablet 10's include stimulating ovulation, improving fertility outcomes, making conception planning easier, and providing a convenient oral treatment option.

  • Promotes regular ovulation: Stimulates the ovaries to release a mature egg, increasing the opportunity for natural conception.
  • Improves the chances of pregnancy: By restoring ovulation in women with ovulatory disorders, it helps increase the likelihood of successful fertilisation.
  • Supports better conception planning: A more predictable ovulation window makes it easier to time intercourse or assisted reproductive procedures.
  • Convenient oral treatment: Provides an effective fertility treatment that can be taken as tablets at home under your doctor's supervision, avoiding the need for injectable medications in many cases.
Side effects of Clo-mature-25 Tab
  • Schedule a comprehensive medical evaluation with a specialized women's health expert.
  • Adhere to a personalized medication regimen to alleviate symptoms and promote ovarian health.
  • Embrace a holistic approach to wellness, incorporating nutritious eating habits and consistent physical activity.
  • Refrain from engaging in physically demanding tasks that may exacerbate discomfort.
  • Prioritize rejuvenation and relaxation, ensuring adequate sleep and downtime.
  • Explore complementary therapies, like acupuncture or botanical supplements, under the guidance of a qualified medical professional.
  • Call and consult your doctor if you observe prolonged and unusual bleeding during menstruation cycle.
  • Drink more fluids and your doctor may prescribe a suitable medication to reduce the bleeding.
  • Ensure to use the right hygiene products to prevent leakage and discomfort.
  • Talk to your doctor to know the cause, severity and appropriate treatment options.
  • Try pain relievers like ibuprofen or naproxen to relieve mild pelvic pain.
  • Consider pelvic floor exercises as it helps to strengthen muscles in the pelvic region and relieve pain.
  • Try relaxation techniques like deep breathing, meditation or gentle stretching.
  • Vaginal bleeding can be abnormal if it is not related to menstruation, and needs immediate attention and cannot be ignored.
  • Get a physical examination and follow your doctor's instructions to get relief from bleeding.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Prefer practicing yoga and meditation to reduce stress and anxiety, as it can worsen vaginal bleeding.
  • Take a balanced diet and manage your weight.
  • Vaginal bleeding can be abnormal if it is not related to menstruation, and needs immediate attention and cannot be ignored.
  • Get a physical examination and follow your doctor's instructions to get relief from bleeding.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Prefer practicing yoga and meditation to reduce stress and anxiety, as it can worsen vaginal bleeding.
  • Take a balanced diet and manage your weight.
  • Discuss with your doctor to identify the cause, severity, and appropriate treatment options.
  • Try pain relievers like ibuprofen or naproxen to relieve mild pelvic pain.
  • Consider pelvic floor exercises as they can help to strengthen muscles in the pelvic region and relieve pain.
  • Try relaxation techniques like deep breathing, meditation, or gentle stretching.

Directions for Use

  • Clo-Mature-25 Tablet 10's can be taken with or without food.
  • It is usually taken once daily for 5 days, starting on the 5th day of your menstrual period or follow your doctor's instructions for effective use.
  • Swallow the Clo-Mature-25 Tablet 10's as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Clo-Mature-25 Tablet 10's Works

Clo-Mature-25 Tablet 10's contains clomifene citrate, a selective oestrogen receptor modulator (SERM) that helps stimulate ovulation in women who have difficulty releasing eggs regularly. Clo-Mature-25 Tablet 10's works by blocking the action of oestrogen at specific receptors in the brain, particularly in the hypothalamus. This makes the body perceive that oestrogen levels are lower than they actually are, prompting the brain to stimulate the pituitary gland. In response, the pituitary gland releases increased amounts of follicle-stimulating hormone (FSH) and luteinising hormone (LH). These hormones act on the ovaries to stimulate the growth and maturation of ovarian follicles and trigger the release of a mature egg during ovulation. Together, these actions help promote regular ovulation and increase the chances of conception in women with ovulatory disorders.
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Alcohol

Caution

Avoid alcohol consumption as it may worsen your condition and increase the risk of side effects.

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Pregnancy

Unsafe

Clo-Mature-25 Tablet 10's is a category X drug. Clo-Mature-25 Tablet 10's is not recommended for pregnant women as it may cause birth defects/congenital disabilities in the unborn baby.

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Breast Feeding

Caution

Clo-Mature-25 Tablet 10's decreases the supply of breast milk. So, it should be used with caution in breastfeeding mothers.

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Driving

Caution

Clo-Mature-25 Tablet 10's may cause vision problems, so do not drive or operate heavy machinery after taking Clo-Mature-25 Tablet 10's unless your vision is normal.

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Liver

Caution

Clo-Mature-25 Tablet 10's should be used with extreme caution in patients with liver disease as the liver metabolises Clo-Mature-25 Tablet 10's. Dose adjustments may be necessary.

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Kidney

Caution

Please consult your doctor if you have kidney problems before starting Clo-Mature-25 Tablet 10's.

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Children

Unsafe

Clo-Mature-25 Tablet 10's is not recommended for use in children.

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Heart

Caution

Clo-Mature-25 Tablet 10's should be taken with caution in patients with pre-existing heart conditions. Therefore, please inform your doctor before using Clo-Mature-25 Tablet 10's.

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Geriatrics

Unsafe

Clo-Mature-25 Tablet 10's is generally not recommended for elderly patients due to an increased risk of side effects and reduced effectiveness.

What if I have taken an overdose of Clo-Mature-25 Tablet 10's

If you take more than the prescribed amount of Clo-Mature-25 Tablet 10's, seek immediate medical attention or contact your local poison control centre right away. Symptoms of an overdose can include severe nausea, vomiting, hot flashes, or pelvic pain.

Diet & Lifestyle Advise

  • Track your ovulation: Use ovulation predictor kits or track your basal body temperature daily to help identify your most fertile days.
  • Maintain a moderate weight: Reaching or maintaining a healthy weight range can optimize ovarian response and improve your overall chances of conception.
  • Manage daily stress: High stress levels can disrupt hormone balance. Consider low-impact activities like gentle walking, breathing exercises, or prenatal yoga.
  • Limit alcohol and caffeine: Avoid alcohol entirely during your cycle, and limit caffeine intake to moderate levels, as these substances can affect reproductive outcomes.
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Have a query?

How Soon It Starts Working

The time required for Clo-Mature-25 Tablet 10's to start to work: The time required for Clo-Mature-25 Tablet 10's to show its action is unknown. The time for which the effects of Clo-Mature-25 Tablet 10's last: The duration of action for Clo-Mature-25 Tablet 10's is unknown.

What if you forget to take Clo-Mature-25 Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed tablet and continue with your regular schedule. Do not take a double dose to make up for a missed one. Contact your doctor or pharmacist for guidance if you miss more than one dose.

Storage

• Store Clo-Mature-25 Tablet 10's tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Watch for vision changes: If you experience any blurred vision or spots in your eyes, stop taking the medication and call your doctor immediately. These symptoms can sometimes persist even after stopping the drug.
  • Be aware of multiple births: Using Clo-Mature-25 Tablet 10's increases the likelihood of a multiple pregnancy (such as twins or triplets). Discuss this possibility and the associated risks with your doctor before starting treatment.
  • Recognise OHSS symptoms: This medicine can sometimes overstimulate the ovaries. Contact your clinic immediately if you notice rapid weight gain, severe abdominal swelling, nausea, or decreased urination.
  • Exercise caution while driving: Dizziness or mild vision disturbances can occur during treatment. Avoid driving or operating machinery until you know how this medication affects you.
  • Complete scheduled monitoring: Attend all scheduled ultrasound scans and blood tests. These monitoring steps are vital for evaluating how your ovaries are responding and ensuring your safety.

Drug-Drug Interactions

verifiedApollotooltip
  • Other fertility treatments: Combining Clo-Mature-25 Tablet 10's with other medications that stimulate ovulation, such as gonadotropins, can significantly increase the risk of overstimulating the ovaries.
clomipheneOspemifene
Critical
clomipheneFluoroestradiol (18f)
Severe

Drug-Drug Interactions

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clomipheneOspemifene
Critical
How does the drug interact with Clo-mature-25 Tab:
Co-administration of Clomifene with Ospemifene can increase the seriousness of side effects.

How to manage the interaction:
Taking Clo-mature-25 Tab with Ospemifene is not recommended, please consult a doctor before taking it.
clomipheneFluoroestradiol (18f)
Severe
How does the drug interact with Clo-mature-25 Tab:
Co-administration of Fluoroestradiol F 18 together with Clo-mature-25 Tab may reduce the action of Fluoroestradiol F 18.

How to manage the interaction:
Taking Clo-mature-25 Tab with Fluoroestradiol (18f) together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
clomipheneBexarotene
Severe
How does the drug interact with Clo-mature-25 Tab:
Co-administration of Clo-mature-25 Tab with Bexarotene may increase the risk of pancreatitis, or inflammation of the pancreas.

How to manage the interaction:
Although there is an interaction, Clo-mature-25 Tab can be taken with Bexarotene if prescribed by the doctor. Consult the prescriber if you experience symptoms of pancreatitis such as persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid drinking alcohol while taking this medicine. Alcohol can increase side effects like dizziness, drowsiness, and hot flashes.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[GYNECOLOGY RELATED DRUGS]

FAQs

Clo-Mature-25 Tablet 10's belongs to the group of medications called 'ovulation stimulants' used to treat infertility in women who are not ovulating (producing an egg) properly or have irregular or no menstrual cycle.
Clo-Mature-25 Tablet 10's works by stimulating the production of necessary hormones for ovulation. Thus, it enhances fertility by inducing ovulation in women with fertility problems.
In most cases, women ovulate within 7 to 10 days after taking this medicine. However, ask your doctor if you have any questions regarding the benefits of Clo-Mature-25 Tablet 10's.
Clo-Mature-25 Tablet 10's can only enhance your chances of fertility. Not getting pregnant after taking this medicine may be due to low dosage, other underlying causes of infertility, or any comorbid conditions that interfere with Clo-Mature-25 Tablet 10's action. Consult your doctor to know the exact reason.
Most women ovulate 7 to 10 days following their last Clo-Mature-25 Tablet 10's dose. It would help if you had intercourse every day or every other day from Day 11 through Day 21 of your cycle.
Clo-Mature-25 Tablet 10's is a fertility medicine used to treat a variety of infertility difficulties. It works by increasing the development of eggs inside the ovaries' follicles. This can also help develop more mature follicles, resulting in the release of numerous eggs during ovulation, increasing your chances of conceiving a twin, triplet, or more.
Clo-Mature-25 Tablet 10's is not a cure for infertility. It can only enhance your chance of getting pregnant by inducing ovulation.
Clo-Mature-25 Tablet 10's is used to treat infertility. Do not use Clo-Mature-25 Tablet 10's for any other condition without a doctor’s advice.
Clo-Mature-25 Tablet 10's is prescribed for the treatment of infertility in women and does not play a role in enhancing sperm count or quality.
Clo-Mature-25 Tablet 10's can cause side effects such as headache, tiredness, dizziness, breast pain or tenderness, heavy periods, or bleeding between periods. Please, consult the doctor if these persist longer.
You should not take this medicine if you have ovarian cysts, unless they are a result of polycystic ovary syndrome (PCOS). Your doctor will perform a pelvic exam or ultrasound to ensure your ovaries are clear before starting each treatment cycle. Talk to your doctor if you have concerns about cysts.
If you notice any changes in your sight, such as blurriness or double vision, stop taking the medication immediately and contact your doctor. You should also avoid driving or using machinery. Talk to your doctor or seek medical help right away.
It is highly recommended to avoid alcohol during your treatment cycle. Alcohol can worsen side effects like hot flashes, headaches, and dizziness, and may also affect overall reproductive health. Talk to your doctor or pharmacist if you have questions.
You can take this medicine at any time of day, but you should take it at the same time each day to keep your hormone levels steady. Some women prefer taking it in the evening to help sleep through mild side effects like hot flashes. Talk to your pharmacist for the best scheduling tips.
Generally, most doctors do not recommend using this medication for more than 3 to 6 cycles. If pregnancy is not achieved after this time, other fertility treatment options are usually explored. Talk to your doctor to discuss your treatment plan.
Yes, because this medication alters your hormone levels, some women may experience temporary mood swings, irritability, or feelings of anxiety. These symptoms typically resolve shortly after finishing the 5-day cycle. Talk to your doctor if you experience severe emotional changes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Dino: 24-080, Ground Floor. Nir Nacar Gajularamaram(V). Qutbulapunk Medchal Malkajgirni (dist) Telangana-500-055
Other Info - CLO2265
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