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CLOP E CREAM 20GM contains clobetasol, which is a topical corticosteroid. It is used for the treatment of auto-immune skin disorders such as psoriasis (scaly, itchy, and red patches on the skin), lichen planus (purplish, itchy, and flat bumps on the wrists, forearms, or legs), discoid lupus erythematosus (red, coin-shaped scales or crusts on the scalp, cheeks, and ears), and eczema (red and itchy skin).  Autoimmune skin disorders are conditions in which immune cells attack the healthy cells of the body, causing inflammation. CLOP E CREAM 20GM can suppress the immune system and reduce inflammation. 

CLOP E CREAM 20GM is available only for topical use in various forms including cream, ointment, and shampoo. Your doctor will advise you which dosage form of clobetasol is suitable based on the infected place. And also suggested how often you need to take CLOP E CREAM 20GM based on your medical condition. While applying, make sure it does not come in contact with the eye. In case CLOP E CREAM 20GM comes in contact with eyes accidentally, rinse with warm water thoroughly. Please do not use it on unaffected areas or for other skin infections without informing your doctor.

Common side-effects of CLOP E CREAM 20GM are burning or stinging sensation in the eye, itching, redness, dryness, and swelling of the skin at the site of application. Long-term use of CLOP E CREAM 20GM may have an effect on the adrenal gland and cause abnormal effects. It may also vision problems in some cases. 

Inform your doctor if you are allergic to clobetasol or any of the other ingredients present in this medicine. Do not use CLOP E CREAM 20GM in children under 12 years of age without a doctor’s advice. Do not use CLOP E CREAM 20GM to treat acne, rosacea (facial flushing on and around the nose), perioral dermatitis (red or scaly rashes around the mouth), anogenital pruritis (itching around the anus or genitals), itchy, broken, or infected skin which is not inflamed, and widespread plaque psoriasis (except single lesions).


Autoimmune skin diseases such as psoriasis, eczema, lichen planus, and discoid lupus erythematosus

Medicinal Benefits

The skin gets inflamed when chemical mediators release chemicals into the skin that cause inflammation. It leads to rashes, swelling, and itching, which can be treated by CLOP E CREAM 20GM. It targets the immune system and lowers the immune response, providing some time for the inflamed skin to heal.

Directions for Use

CLOP E CREAM 20GM is available only for external use. Wash your hands before and after applying the medication. Also, clean and dry the affected area before applying the medication. Cream or ointment: Take the prescribed amount of CLOP E CREAM 20GM cream or ointment and gently rub it on the affected area. Do not use other creams or moisturizers at the same time. If you are using plaster or bandage for dressing at the site of application, wait at least 10 min after applying the medication. Shampoo: Take the recommended amount of shampoo on the dry scalp and leave it for about 15 minutes. Do not cover the scalp with a shower cap. Then, rinse the hair thoroughly with water.


Store in a cool and dry place away from sunlight

Side Effects of CLOP E CREAM 20GM

Unfortunately, like all other medicines, CLOP E CREAM 20GM also may cause some side effects including burning or stinging sensation in the eye, itching, dryness, swelling, irritation, or redness at the application site, or red bumps filled with pus may occur after the initial treatment. These side-effects improve when the body adjusts to the medication. If the condition doesn’t improve, talk to your doctor immediately. Long-term use of CLOP E CREAM 20GM may result in skin thinning, acne, allergic reaction, hair growth, and permanent stretch marks at the site of application, and folliculitis (inflammation of hair follicles), if applied on the scalp. In rare cases, CLOP E CREAM 20GM may enter into the bloodstream from the skin. Contact your doctor promptly if you experience unusual or extreme fatigue, vision disturbances.

In-Depth Precautions and Warning

Drug Warnings

Inform your doctor before using CLOP E CREAM 20GM, if you have previously had an allergic reaction (hypersensitivity) with another steroid. If there is an overdose, clean the area thoroughly and re-apply the medicine. Apply the medication carefully if you are using it on eyelids or near the eyes, as there is a risk of cataracts or glaucoma if the drug enters the eye frequently. CLOP E CREAM 20GM can enter the skin easily and may cause skin thinning because of repeated application. So, apply it carefully when using on broken or damaged skin and large surface area of skin. Inform your doctor immediately if you experience vision problems or any other abnormal signs. Do not use CLOP E CREAM 20GM at the same time as other creams or ointments such as a moisturiser. Wait at least 30 minutes between using clobetasol and any other product.

Safety Advice

  • Safety Warning


    CLOP E CREAM 20GM may not interact with alcohol.

  • Safety Warning


    Pregnant women should consult a doctor before using CLOP E CREAM 20GM.

  • Safety Warning

    Breast Feeding

    CLOP E CREAM 20GM should be used with caution in breastfeeding mothers. However, if prescribed by your doctor and CLOP E CREAM 20GM is applied on the chest, make sure the affected area does not come into contact with the baby's mouth while breastfeeding.

  • Safety Warning


    CLOP E CREAM 20GM does not show any effect on driving. But contact a doctor if you get any problems with your vision. Do not drive if you have problems with your eyesight after using CLOP E CREAM 20GM.

  • Safety Warning


    CLOP E CREAM 20GM should be used with caution in patients with liver diseases.

  • Safety Warning


    CLOP E CREAM 20GM should be used in patients with kidney diseases only when prescribed by a doctor.

Habit Forming


Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherry, broccoli, spinach and blueberries.
  • Consuming food rich in probiotics helps in developing the immune system against allergies.
  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
  • Avoid consumption of foods with excess sugar as it may flare-up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Avoiding getting in contact with harsh soaps, detergents and rough fabrics.

Other Information (CLO0091)

This item is Not Returnable.

Expires on or after - Mar-22

Patients Concern

Disease/Condition Glossary

Eczema is the name for a group of conditions that cause the skin to become dry and irritated. or eczema, a condition that causes the skin to become itchy, dry and cracked.

Psoriasis is a skin condition that causes red, flaky, crusty patches of skin covered with silvery scales. The severity of psoriasis varies greatly from person to person. For some, it's just a minor irritation, but for others, it can majorly affect their quality of life. Psoriasis is a long-lasting (chronic) disease that usually involves periods when you have no symptoms or mild symptoms, followed by periods when symptoms are more severe.

Lichen planus is a rash that can affect different parts of your body, including the inside of your mouth. Lichen planus on your skin can be very itchy, but not always.

Lupus is a long-term condition that causes joint pain, skin rashes and tiredness. There's no cure, but symptoms can improve if treatment starts early.


CLOP E CREAM 20GM can bleach and lighten skin. However, the use of CLOP E CREAM 20GM for skin lightening is not clinically established. So, it should be used only when prescribed by a doctor.

CLOP E CREAM 20GM is not recommended for the treatment of burns. It should also be not used on broken skin or open wounds.

CLOP E CREAM 20GM may stimulate hair growth. However, it should be used only when advised by a doctor.

CLOP E CREAM 20GM use in children is very limited and should be advised by a child specialist only.

CLOP E CREAM 20GM may increase blood sugar levels. Consult your doctor immediately if you experience any abnormal signs or symptoms while using CLOP E CREAM 20GM.

Using too much of CLOP E CREAM 20GM or using it for a long time may increase your risk of having adrenal gland problems.

Yes, you are eligible to take vaccines, but tell the doctor or nurse that you're using clobetasol so they can give the vaccine in an untreated area of skin.



Manufacturer/Marketer address

Danneskiold Samsøes Allé 41, DK-1434 Copenhagen K, Denmark, 1 St Katharine’s Way, London E1W 1UN, United Kingdom



MRP: 104.90


20g Ointment in 1 Tube