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compositionComposition:ZUCLOPENTHIXOL-50MG
prescription
Prescription Medicine
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CLOPIXOL ACUPHASE INJECTION is used to treat schizophrenia (a mental illness) and other psychotic disorders. It contains Zuclopenthixol, which works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour, and emotions. Thus, it helps control psychotic illness by preventing the overactivity of dopamine in the brain. Thus, it helps improve feelings, disturbed thoughts, and behaviour.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ZUCLOPENTHIXOL-50MG

Manufacturer/Marketer :

Lundbeck India Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About CLOPIXOL ACUPHASE INJECTION

CLOPIXOL ACUPHASE INJECTION is an injection used to treat severe mental health conditions, including schizophrenia, long-term psychosis, and acute manic episodes. It is prescribed to help calm agitated behavior, reduce confusion, and control disturbing thoughts. By helping to restore the balance of certain natural chemicals in the brain, it supports a clearer thinking process and calmer behavior.

This medicine is given as an injection by a healthcare professional at regular intervals, which can range from every few days to every few weeks depending on your specific needs. Consistency in receiving your scheduled injections is vital to keep your symptoms under control and prevent them from returning. While receiving this treatment, maintaining a stable routine, getting regular rest, and staying well-hydrated can help support your overall well-being.

Some people may experience side effects when using CLOPIXOL ACUPHASE INJECTION, such as drowsiness, dry mouth, or mild muscle stiffness. While many side effects are manageable, you must consult your doctor immediately if you experience severe symptoms like high fever, extreme muscle rigidity, rapid breathing, or unusual, uncontrollable movements of your face or tongue.

Do not take this if you have a severely decreased level of consciousness (such as being in a coma), severe circulatory collapse, or Parkinson's disease. Before starting treatment, talk to your doctor if you have a history of liver damage, kidney disease, heart problems, seizures, or a high risk of stroke.

This injection can interact with other substances; for example, combining it with alcohol can cause dangerous drowsiness and breathing difficulties. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your healthcare provider before receiving this injection to ensure it is safe for your specific situation.

Uses of CLOPIXOL ACUPHASE INJECTION

This medicine is used to treat certain psychiatric conditions by helping restore the balance of chemicals in the brain. The detailed uses of this medicine are as follows:

  • Schizophrenia: CLOPIXOL ACUPHASE INJECTION helps manage long-term symptoms such as hallucinations, delusions, suspiciousness, and disorganized thinking.
  • Acute psychosis: It helps control severe episodes of psychosis, reducing agitation, confusion, and highly disturbed behavior.
  • Manic episodes: It helps stabilize mood and reduce symptoms such as excessive energy, overactivity, racing thoughts, and impulsive behavior associated with mania.

Key Benefits

CLOPIXOL ACUPHASE INJECTION helps control symptoms of certain mental health conditions and supports long-term symptom management. Its benefits include:

  • Helps reduce symptoms such as hallucinations, delusions, agitation, and disturbed thinking by restoring the balance of brain chemicals.
  • Promotes improved emotional stability, clearer thinking, and better control of behavior.
  • Helps reduce the risk of symptom relapse when used regularly as prescribed.
  • Long-acting injectable formulations provide sustained medication levels, reducing the need for daily tablets and improving treatment adherence.
  • Supports better day-to-day functioning and overall quality of life by helping maintain long-term symptom control.
     
Side effects of Clopixol Acuphase Injection
  • Please inform your doctor about joint swelling, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Maintain a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet.
  • Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Whenever there is swelling, apply heat or cold packs to the affected joint that can help reduce pain and inflammation.
  • Track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Eat smaller meals and chew food thoroughly.
  • Try foods with softer textures.
  • If you have difficulty swallowing liquids, use thickener.
  • Learn new swallowing techniques from a speech and language therapist.
  • Avoid alcohol and caffeine as these may dry your throat and mouth making it more difficult to swallow.
  • Consider alternative forms of feeding, such as feeding tubes through nose or a hole into your stomach.
  • Calm your mind and body with stress-reducing activities, such as meditation, deep breathing, or yoga.
  • Engage in a new hobby or social activities with friends.
  • Incorporate physical activity into your daily routine to manage emotions and urges.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • CLOPIXOL ACUPHASE INJECTION will be administered by a healthcare professional.
  • Do not self-administer.

How CLOPIXOL ACUPHASE INJECTION Works

CLOPIXOL ACUPHASE INJECTION works by targeting chemical messengers in the brain, particularly dopamine. In conditions like schizophrenia and mania, an overactivity of dopamine pathways can lead to hallucinations, confusion, and extreme agitation. CLOPIXOL ACUPHASE INJECTION blocks these dopamine receptors, which helps quiet down the overactive signals and restores a healthier chemical balance. This action calms the nervous system, reduces disorganized thoughts, and helps stabilize your emotional state.
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Alcohol

Unsafe

Avoid consumption of alcohol with CLOPIXOL ACUPHASE INJECTION as it may increase drowsiness.

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Pregnancy

Caution

CLOPIXOL ACUPHASE INJECTION is not recommended for use during pregnancy unless clearly necessary. If CLOPIXOL ACUPHASE INJECTION is used during the third trimester, it may cause muscle stiffness and/or weakness, shaking, sleepiness, difficulty feeding, and breathing problems in the baby. Therefore, please consult a doctor if you are pregnant or planning for pregnancy before taking CLOPIXOL ACUPHASE INJECTION.

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Breast Feeding

Unsafe

CLOPIXOL ACUPHASE INJECTION is not recommended for breastfeeding mothers as it may be excreted in breast milk. However, if you have concerns regarding this, please discuss them with your doctor.

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Driving

Unsafe

There is a risk of dizziness, drowsiness or blurred vision after taking CLOPIXOL ACUPHASE INJECTION, especially at the beginning of your treatment. Avoid driving or operating machinery if you are not alert.

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Liver

Consult your doctor

If you have liver problems, please consult your doctor before taking CLOPIXOL ACUPHASE INJECTION.

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Kidney

Consult your doctor

If you have kidney problems, please consult your doctor before taking CLOPIXOL ACUPHASE INJECTION.

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Children

Unsafe

CLOPIXOL ACUPHASE INJECTION is not recommended for children as safety and effectiveness were not established.

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Heart

Caution

CLOPIXOL ACUPHASE INJECTION may affect heart rhythm and should be used cautiously in patients with heart problems. Always consult your doctor for ECG monitoring and safer alternatives before starting treatment.

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Geriatrics

Caution

CLOPIXOL ACUPHASE INJECTION can be used in geriatric patients, but with caution due to slower drug metabolism and increased sensitivity to side effects. Lower doses and close monitoring are recommended to ensure safety.

What if I have taken an overdose of CLOPIXOL ACUPHASE INJECTION

Since this injection is given by a healthcare professional, an overdose is highly unlikely. However, if you suspect you have received too much or experience severe sleepiness, shaking, rapid heartbeats, or loss of consciousness, seek emergency medical attention right away.

Diet & Lifestyle Advise

  • Manage weight changes: Antipsychotic medications can sometimes cause weight gain. Focus on a diet rich in vegetables, fruits, lean proteins, and whole grains, and try to include regular physical activity like walking in your daily routine.
  • Relieve dry mouth: Sip water frequently throughout the day, chew sugarless gum, or suck on sugar-free hard candies to stimulate saliva production.
  • Prevent dizziness: To avoid feeling dizzy or fainting, take your time when moving from a lying or sitting position to standing.
  • Stay hydrated in hot weather: This medicine can make it harder for your body to cool itself down. Drink plenty of water and avoid spending long periods in extreme heat.
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How Soon It Starts Working

The time required for CLOPIXOL ACUPHASE INJECTION to start to work: CLOPIXOL ACUPHASE INJECTION shows its effect within 2 to 4 hours of IM administration. The time for which the effects of CLOPIXOL ACUPHASE INJECTION last: CLOPIXOL ACUPHASE INJECTION effect last for 2 to 3 days of IM administration.

What if you forget to take CLOPIXOL ACUPHASE INJECTION

If you miss an appointment for your injection, contact your doctor or clinic immediately to reschedule. Do not receive a double dose to make up for a missed one.

Storage

•Store CLOPIXOL ACUPHASE INJECTION ampoules or vials in their original packaging to protect them from light. Keep them at room temperature, ideally below 25°C (77°F), and do not freeze them.

Drug Warnings

  • Inspect the vial: If you are assisting in your care, always check that the solution is clear and free of particles before the healthcare provider injects it.
  • Rotate injection sites: Ensure your healthcare provider rotates the injection site between the buttocks or arms to prevent muscle soreness and skin irritation.
  • Avoid driving initially: Do not drive, operate machinery, or perform hazardous tasks until you know how this medicine affects your alertness.
  • Avoid alcohol: Do not drink alcohol while receiving this treatment, as it can dangerously increase drowsiness and slow down your reflexes.
  • Monitor body temperature: Be alert to unexplained fevers or severe muscle stiffness, and report them to your care team immediately.

Drug-Drug Interactions

verifiedApollotooltip
  • Sedatives and sleeping pills: Combining these with CLOPIXOL ACUPHASE INJECTION can cause severe drowsiness and slow down your breathing.
  • Blood pressure medicines: This injection may increase the effect of blood pressure drugs, leading to excessively low blood pressure and dizziness.
  • Parkinson's medications: CLOPIXOL ACUPHASE INJECTION may reduce the effectiveness of medicines used to treat Parkinson's disease.
  • Medicines affecting heart rhythm: Combining this injection with certain other drugs can increase the risk of irregular heartbeats.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Alcohol: Avoid alcohol completely, as it can severely increase drowsiness, dizziness, and the risk of breathing problems.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

CLOPIXOL ACUPHASE INJECTION is used to treat Schizophrenia, Mania and other psychotic disorders.
CLOPIXOL ACUPHASE INJECTION contains Zuclopenthixol which works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, CLOPIXOL ACUPHASE INJECTION helps in controlling psychotic illness by preventing the overactivity of dopamine in the brain. Thus, it helps in improving feelings, disturbed thoughts and behaviour.
CLOPIXOL ACUPHASE INJECTION should be used with caution in asthma patients as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you have asthma or other breathing problems before taking CLOPIXOL ACUPHASE INJECTION.
It is not recommended to take CLOPIXOL ACUPHASE INJECTION before surgery. Therefore, it is advised to inform your surgeon, anaesthetist or dentist before any surgery that you are on treatment with CLOPIXOL ACUPHASE INJECTION as it may increase the effects of muscle relaxing drugs, general anaesthesia and drugs used to prevent blood clots.
CLOPIXOL ACUPHASE INJECTION may affect fertility as it reduces sexual activity. However, it is a temporary effect. Please consult a doctor if you are planning pregnancy before taking CLOPIXOL ACUPHASE INJECTION.
CLOPIXOL ACUPHASE INJECTION should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking CLOPIXOL ACUPHASE INJECTION.
You are not recommended to take CLOPIXOL ACUPHASE INJECTION with levodopa (antiparkinson drug) as it may decrease the effectiveness of levodopa and increase the risk of adverse effects such as low blood pressure, drowsiness, light-headedness and dizziness. However, please consult your doctor before using CLOPIXOL ACUPHASE INJECTION with any other medicines.
No, you should not discontinue taking CLOPIXOL ACUPHASE INJECTION on your own as stopping this medication may cause withdrawal symptoms like nausea, vomiting, diarrhoea, restlessness, anxiety, agitation and insomnia. The doctor will reduce the dose gradually to prevent withdrawal symptoms.
Do not take larger than the prescribed doses. Taking more than the recommended dose does not provide extra relief but it can increase the risk of side effects like coma, hypo or hyperthermia, extreme drowsiness and shock. However, it is unlikely to exceed the recommended dose of CLOPIXOL ACUPHASE INJECTION as it will be administered by the doctor.
The side effects of CLOPIXOL ACUPHASE INJECTION include dry mouth, mouth and eyeballs, muscle pain, drowsiness, tremor, unusual movement of tongue, fainting, constipation, headache or migraine. Consult the doctor if any of these side effects persist or worsen.
No, CLOPIXOL ACUPHASE INJECTION does not cure schizophrenia or psychosis, but it is highly effective at managing and controlling the symptoms. Continuous use helps keep symptoms from returning and allows you to function better in daily life. Talk to your doctor for more details about long-term management.
You should avoid alcohol while receiving this injection. Alcohol can interact with the medicine to cause severe drowsiness, confusion, and coordinate difficulties, and it can also worsen your mental health symptoms. Talk to your doctor or pharmacist if you need help avoiding alcohol.
Yes, weight gain is a common side effect of this class of medication. Managing your diet, eating healthy foods, and staying physically active can help limit weight changes. Talk to your doctor or pharmacist for personalized lifestyle advice.
This medicine can cause significant drowsiness and dizziness, especially when you first start treatment or after a dose change. Do not drive or operate machinery until you are certain that you can do so safely and without impairment. Talk to your doctor if you feel excessively tired.
The frequency depends on whether you are receiving the short-acting form (often given every few days for acute episodes) or the long-acting depot form (usually given every 2 to 4 weeks for maintenance). Your healthcare provider will establish a schedule that is right for you. Talk to your doctor about your injection schedule.
Mild muscle stiffness can sometimes occur. However, if the stiffness is severe, accompanied by a high fever, or if you experience uncontrollable movements of your muscles, contact your doctor immediately, as these can be signs of serious side effects. Talk to your doctor right away if you notice these symptoms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Lundbeck India Private Limited, "H M Towers", I Floor, #58, Brigade Road, Kodihalli BDA, HAL II Stage, 560 025, Bangalore, India
Other Info - CLO0056

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