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  3. Clotide Injection 10 ml

Clotide Injection 10 ml, Pack of 1 INJECTION
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Clotide Injection is used to treat Myocardial Infarction and Acute Coronary Syndrome. It contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This inhibits fibrinogen binding, reducing the chance of blood clot formation. Clotide Injection reduces the risk of cardiovascular events like myocardial infarction (heart attack).

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Composition :

EPTIFIBATIDE-20MG

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Clotide Injection

Clotide Injection belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. Clotide Injection is used in the treatment of Acute coronary syndrome (ACS) in both patients who need to be managed medically and also people undergoing percutaneous coronary intervention (PCI) procedures. ACS is defined as a group of serious cardiac conditions wherein the blood flow to the heart decreases due to plaque formation. Clotide Injection is also used in the treatment of patients undergoing urgent PCI procedures and also in patients undergoing intracoronary stenting.

Clotide Injection contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Clotide Injection reduces the risk of cardiovascular events like myocardial infarction (heart attack).

Clotide Injection may cause certain side effects, such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, decreased platelet count, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer Clotide Injection. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Clotide Injection should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, history of bleeding diathesis within 30 days, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, renal failure, using another glycoprotein IIb/IIIa inhibitor, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, as it can cause serious adverse effects. Clotide Injection is known to cause bleeding problems. If you observe severe bleeding that cannot be controlled, it is advised to stop administering Clotide Injection immediately. Hence, close monitoring is needed for any bleeding conditions. Talk to your doctor before receiving Clotide Injection if you had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before taking Clotide Injection. Clotide Injection is not recommended for children below 12 years of age as efficacy and safety have not been established.

Uses of Clotide Injection

Clotide Injection is used to prevent heart attacks in high-risk patients. The detailed uses of Clotide Injection are as follows:<br/>• Prevents early myocardial infarction: Clotide Injection is used for unstable angina or non-Q-wave myocardial infarction, especially within 24 hours of chest pain.<br/>• Recommended for high-risk patients: Clotide Injection is beneficial for those with ECG changes, elevated cardiac enzymes, or those likely to undergo early PTCA.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Clotide Injection will be administered in the hospital setting by a trained healthcare professional.• Do not self-administer.

Medicinal Benefits

Clotide Injection contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Clotide Injection results in reducing the risk of cardiovascular events like myocardial infarction (heart attack) and other cardiac events.

How Clotide Injection Works

Clotide Injection contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Clotide Injection reduces the risk of cardiovascular events like myocardial infarction (heart attack).

Storage

• Store in a cool and dry place away from sunlight.
• Keep Clotide Injection out of the sight and reach of children.
• Cold chain - To be stored in cold places at 2ºC to 8ºC.

What if I have taken an overdose of Clotide Injection

As Clotide Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Do not receive Clotide Injection if you are allergic to it. It is contraindicated in patients who have active internal bleeding, history of bleeding diathesis within 30 days, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, renal failure, using another glycoprotein IIb/IIIa inhibitor, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, as it can cause serious adverse effects. Clotide Injection is known to cause bleeding problems. However, if you observe severe bleeding that cannot be controlled, it is advised to stop administering Clotide Injection immediately. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Clotide Injection if you had a recent severe injury or surgery due to the risk of severe bleeding problems. Before taking Clotide Injection inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding due to serious foetal harm. Clotide Injection is not recommended for children below 12 years of age as efficacy and safety have not been established. Talk to your doctor before receiving Clotide Injection if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems.

Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

Therapeutic Class

ANTIFIBRINOLYTIC AGENTS

Clotide Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption. Consult your doctor for more information.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Clotide Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Clotide Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Not applicable

Clotide Injection is used in PCI procedures in a hospital setting. Driving is not recommended.

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Liver

Caution

If you have liver problems, inform your doctor beforehand.

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Kidney

Caution

If you have kidney impairment, inform your doctor beforehand. Clotide Injection is not recommended for use in patients with renal toxicity.

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Children

Unsafe

Clotide Injection is not recommended for use in children below 12 years of age, as efficacy and safety have not been established.

Have a query?

FAQs

Clotide Injection is used to treat Myocardial Infraction and Acute Coronary Syndrome.

Clotide Injection contains Eptifibatide (anti-glycoprotein IIb/IIIa receptor), which works by blocking the glycoprotein IIb/IIIa receptor&#039;s activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation.

Clotide Injection is known to increase the risk of bleeding. However, if the patient has uncontrollable bleeding, discontinue the medicine immediately.

Clotide Injection may cause anaemia (low haemoglobin and low red blood cell count). So, it would be best to include iron-rich food in your diet to prevent anaemia.

Country of origin

India

Manufacturer/Marketer address

20th KM, Hosur Road, Electronic City, Bengaluru 560100, Karnataka, India
Other Info - CLO0152

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://www.ncbi.nlm.nih.gov/books/NBK541066/
  2. https://go.drugbank.com/drugs/DB00063
  3. https://reference.medscape.com/drug/integrilin-eptifibatide-342149#4
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020718s037lbl.pdf
  5. https://www.rxlist.com/integrilin-drug.htm

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