Buy Cloza-100 Tablet online | Uses, Side Effects, Price and substitutes

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Prescription Medicine

Cloza-100 Tablet is used to treat schizophrenia. Additionally, it is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. It contains Clozapine, which helps in improving mood, behaviour and thoughts. It may cause side effects such as tachycardia (fast heartbeat), dizziness, headache, tremor, sweating, dry mouth, nausea, constipation and visual disturbances. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

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More about the Product

Composition :

CLOZAPINE-100MG

Manufacturer/Marketer :

Core Claris Lifesciences Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Cloza-100 Tablet

Cloza-100 Tablet is a prescription medicine used to manage severe symptoms of schizophrenia when other treatments have not been successful. It is a specialized mental health treatment that helps restore chemical balances in the brain. This medication is also prescribed to lower the risk of suicidal thoughts and behaviors in individuals diagnosed with schizophrenia or schizoaffective disorder.

To experience the full benefits, you must take Cloza-100 Tablet consistently and exactly as directed by your healthcare provider. This medicine can be taken with or without food, making it easy to incorporate into your daily routine. Adopting healthy habits, such as eating a balanced diet and engaging in regular physical activity, can also help you manage your weight and overall health while using this medication.

While taking this medicine, some patients may experience mild side effects like drowsiness, increased drooling (especially while sleeping), and a faster heart rate. However, you must contact your doctor immediately if you develop any signs of infection, such as a fever, sore throat, or sudden body aches. These can be early warning signs of a serious drop in your body’s white blood cells.

Do not take this if you have a history of severe bone marrow disorders, uncontrolled seizures, or severe heart problems. Before starting Cloza-100 Tablet , inform your doctor if you have a history of liver damage, kidney disease, glaucoma, or severe constipation. This helps ensure the medicine is safe for your specific health profile.

Additionally, Cloza-100 Tablet can interact with other substances; for instance, drinking alcohol can increase drowsiness, and changes in smoking habits can alter how the medicine works in your body. If you are pregnant, planning to breastfeed, or are an older adult, consult your healthcare provider to discuss the risks and necessary safety monitoring.

Uses of Cloza-100 Tablet

Cloza-100 Tablet is used in the treatment of schizophrenia. The detailed uses of Cloza-100 Tablet are as follows:

Treatment-resistant schizophrenia: Cloza-100 Tablet helps control severe hallucinations, delusions, and disorganised thinking in individuals who have not seen improvement with other standard antipsychotic medications.
Suicidal behaviour in schizophrenia: Cloza-100 Tablet helps reduce the risk of recurring suicidal thoughts and self-harming behaviours in patients living with schizophrenia or schizoaffective disorder.

Key Benefits

Cloza-100 Tablet provides critical support for individuals struggling with severe mental health symptoms, helping them regain stability and improve their daily quality of life. By targeting specific imbalances in the brain, this medicine offers deep, clinically proven relief where other standard treatments may have failed.

Key benefits of this medication include:

Clearer thinking: It reduces the severity of disruptive thoughts, helping you focus better and communicate more easily with others.
Fewer sensory disturbances: It helps quiet hallucinations, such as hearing voices or seeing things that are not there, allowing you to feel more grounded.
Reduced emotional distress: It lowers feelings of extreme suspicion, fear, and anxiety, which helps improve social safety and overall comfort.
Better daily functioning: With stabilised thoughts and emotions, it becomes much easier to participate in daily routines, work, and social activities.

Side effects of Cloza-100 Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Sedation

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Fast Heart Rate

Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):

Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.

Low Blood Pressure

Managing Low Blood Pressure Triggered by Medication: Expert Advice:

If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
Take regular breaks to sit or lie down if you need to stand for long periods.
When lying down, elevate your head with extra pillows to help improve blood flow.
Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

Excessive Saliva Production

Regularly brush your tongue and teeth to prevent Excessive Saliva Production.
Avoid eating foods high in sugar or acid since these foods might increase saliva production, which increases the Excessive Saliva Production.
Keep your head up straight and maintain proper posture to prevent saliva from collecting in your mouth.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

Always take this medicine exactly as your doctor has prescribed. Follow these general guidelines for safe use:

Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet unless your doctor specifically instructs you to do so.
You can take Cloza-100 Tablet with or without food. Taking it at the same time each day can help you remember your doses and keep steady levels of the medicine in your body.
Your doctor will guide you to start with a very low dose and gradually increase it over several weeks. This gradual process helps your body adjust and reduces the risk of side effects.
Do not change your dose or stop taking this medicine suddenly without consulting your doctor, even if you feel completely well.

How Cloza-100 Tablet Works

Cloza-100 Tablet belongs to a group of medicines known as atypical antipsychotics. It works by rebalancing the levels of certain natural chemicals in your brain, specifically dopamine and serotonin. In conditions like schizophrenia, these chemical messengers are often overactive, causing mismanaged brain signals that lead to hallucinations, delusions, and confused thoughts. Cloza-100 Tablet works by carefully blocking and stabilising the receptors for these chemicals, calming hyperactive pathways in the brain. This action helps restore a calmer, more organised flow of thoughts. Because it acts on multiple chemical pathways simultaneously, it is often effective even when other medications targeting only one pathway have not worked.

Alcohol

Unsafe

Avoid consumption of alcohol while taking Cloza-100 Tablet as it may cause increased drowsiness.

Pregnancy

Caution

Cloza-100 Tablet belongs to pregnancy category B. Please consult your doctor if you are pregnant before taking this medicine; your doctor will prescribe only if the benefits outweigh the risks.

Breast Feeding

Unsafe

Cloza-100 Tablet is not recommended for use during breastfeeding.

Driving

Unsafe

Cloza-100 Tablet causes tiredness, dizziness and vision problems. Do not drive or operate machinery if you experience these symptoms.

Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

Children

Unsafe

Cloza-100 Tablet should not be given to children as safety and effectiveness have not been established.

Heart

Caution

Cloza-100 Tablet should be taken with extreme caution in patients with heart disease. Please consult your physician.

Geriatrics

Caution

Cloza-100 Tablet can be given in elderly patients with caution due to increased risk of adverse effects.

What if I have taken an overdose of Cloza-100 Tablet

If you suspect an overdose, seek immediate emergency medical help or call your local poison control centre. Symptoms of an overdose may include extreme drowsiness, a very slow or irregular heartbeat, shallow breathing, fainting, or seizures.

Diet & Lifestyle Advise

Managing your diet and lifestyle can play an important role in keeping you healthy and comfortable while taking Cloza-100 Tablet .

Manage constipation with fiber and water: Since this medicine can slow down your digestion, drink plenty of water throughout the day and eat high-fiber foods like vegetables, fruits, and whole grains to prevent severe constipation.
Monitor weight and diet: To help manage weight gain and blood sugar fluctuations, focus on a balanced diet with controlled portions and limit processed foods, sugary drinks, and snacks.
Stay safe in hot weather: This medication can make it harder for your body to regulate temperature. Drink extra fluids, wear light clothing, and avoid prolonged heavy exercise in hot weather.
Stand up slowly: To prevent dizziness or fainting from a sudden drop in blood pressure, take your time when moving from a lying or sitting position to standing.
Keep physical activity regular: Gentle daily exercises like walking can support your metabolic health, lift your mood, and help manage your weight.

Have a query?

How Soon It Starts Working

The time required for Cloza-100 Tablet to start to work: Cloza-100 Tablet ideally shows its action within 1.5 to 2.5 hours after administration.
The time for which the effects of Cloza-100 Tablet last: The effect of Cloza-100 Tablet lasts for 4 to 12 hours.

What if you forget to take Cloza-100 Tablet

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one and continue back to your regular dosage routine. Avoid taking two doses at once.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Never skip your blood tests: Regular blood tests are mandatory while taking Cloza-100 Tablet to check your white blood cell count. This is a vital safety measure, and the medicine cannot be refilled without these tests.
Watch for signs of infection: Report any fever, sore throat, or flu-like symptoms to your doctor immediately. Do not wait for your next scheduled blood test.
Inform your doctor about smoking habits: Smoking cigarettes can lower the level of this medicine in your blood. Tell your doctor if you start, stop, or change your smoking habits so they can adjust your dose safely.
Do not stop treatment abruptly: Stopping Cloza-100 Tablet suddenly can cause severe withdrawal symptoms and a quick return of your original illness. Always taper off gradually under your doctor's close supervision.
Avoid driving initially: Do not drive, ride a bicycle, or operate machinery until you are certain how this medicine affects your alertness and coordination.
Avoid alcohol completely: Alcohol can dangerously increase the sedative effects of this medicine, leading to severe drowsiness, confusion, or breathing difficulties.

Drug-Drug Interactions

Drug-Drug Interactions:

Medicines affecting blood cells: Combining Cloza-100 Tablet with other drugs that can lower your white blood cell count (such as certain cancer treatments or immunosuppressants) can be very dangerous and must be avoided.
Sedatives and pain medicines: Taking this medicine with sleeping pills, strong pain relievers, or anxiety medications can lead to extreme sleepiness, shallow breathing, and low blood pressure.
Heart and liver medicines: Certain medications that affect your heart rhythm or change how your liver processes medications may raise or lower the levels of Cloza-100 Tablet in your blood, requiring close monitoring.

ClozapineCisapride

Critical

ClozapineSparfloxacin

Critical

Drug-Drug Interactions

ClozapineCisapride

Critical

How does the drug interact with Cloza-100 Tablet:
When Cloza-100 Tablet is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Cloza-100 Tablet with Cisapride there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.

ClozapineSparfloxacin

Critical

How does the drug interact with Cloza-100 Tablet:
When Cloza-100 Tablet is taken with Sparfloxacin, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Cloza-100 Tablet with Sparfloxacin there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.

ClozapineMetoclopramide

Critical

How does the drug interact with Cloza-100 Tablet:
Co-administration of Metoclopramide with Cloza-100 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Cloza-100 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

ClozapineFlibanserin

Critical

How does the drug interact with Cloza-100 Tablet:
When Flibanserin and Cloza-100 Tablet are taken together, may increase side effects.

How to manage the interaction:
There may be a possibility of interaction between Cloza-100 Tablet and Flibanserin, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, drowsiness, fatigue, and difficulty concentrating, call a doctor right away. Do not stop using any medications without a doctor's advice.

ClozapineRopinirole

Critical

How does the drug interact with Cloza-100 Tablet:
When Ropinirole is taken with Cloza-100 Tablet, it may not work as well.

How to manage the interaction:
Taking Ropinirole with Cloza-100 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.

ClozapinePimozide

Critical

How does the drug interact with Cloza-100 Tablet:
When Cloza-100 Tablet is taken with Pimozide, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Cloza-100 Tablet with Pimozide there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.

ClozapinePotassium citrate

Critical

How does the drug interact with Cloza-100 Tablet:
Taking Cloza-100 Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Co-administration of Potassium citrate with Cloza-100 Tablet is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

ClozapineTemazepam

Severe

How does the drug interact with Cloza-100 Tablet:
Combining Temazepam with Cloza-100 Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking Temazepam and Cloza-100 Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. Some reports have shown that when benzodiazepines and Cloza-100 Tablet are taken together, there can be side effects like excessive saliva, difficulty breathing, low blood pressure, unconsciousness, or confusion. Do not stop using any medications without a doctor's advice.

ClozapineThiotepa

Severe

How does the drug interact with Cloza-100 Tablet:
Combining Thiotepa with Cloza-100 Tablet can increase the risk of infection.

How to manage the interaction:
Although taking Thiotepa and Cloza-100 Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

ClozapinePanobinostat

Severe

How does the drug interact with Cloza-100 Tablet:
When Cloza-100 Tablet is taken with Panobinostat, it may increase the risk of irregular heart rhythm and infection.

How to manage the interaction:
Although there is a possible interaction between Panobinostat and Cloza-100 Tablet, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

Drug-Food Interactions:

Caffeine: Consuming large amounts of caffeine (found in coffee, tea, and energy drinks) can significantly increase the levels of Cloza-100 Tablet in your body, raising the risk of side effects. Suddenly stopping caffeine can drop the levels of the medicine, so keep your caffeine intake steady and talk to your doctor before making changes.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

Therapeutic Class

[PSYCHOTHERAPEUTICS]

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Author Details

Written By

Santoshini Reddy G
M Pharmacy

Reviewed By

Bayyarapu Mahesh Kumar
M Pharmacy

Last Updated

Jul 1, 2026 | 5:24 PM IST

We provide you with authentic, trustworthy and relevant information.

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Reference

Country of origin

India

Manufacturer/Marketer address

Claris Corporate Headquarters, Nr. Parimal Crossing, Ellisbridge, Ahmedabad-380006, Gujarat, India

Other Info - CLO1518

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Cloza-100 Tablet 10's

Delivery Information

More about the Product

Composition :

Manufacturer/Marketer :

Consume Type :

Expires on or after :

Return Policy :

NPPA :

About Cloza-100 Tablet

Uses of Cloza-100 Tablet

Key Benefits

Headache

Sedation

Dizziness

Fast Heart Rate

Low Blood Pressure

Excessive Saliva Production

Constipation

Directions for Use

How Cloza-100 Tablet Works

Alcohol

Pregnancy

Breast Feeding

Driving

Liver

Kidney

Children

Heart

Geriatrics

What if I have taken an overdose of Cloza-100 Tablet

Diet & Lifestyle Advise

How Soon It Starts Working

What if you forget to take Cloza-100 Tablet

Storage

Drug Warnings

Drug-Drug Interactions

Drug-Drug Interactions

Drug-Food Interactions

Drug-Food Interactions

All Substitutes & Brand Comparisons

Clozact 100Mg Tablet

CLOMACH 100MG TABLET

Cipin-100 Tablet 10's

Habit Forming

Therapeutic Class

FAQs

What is the use of Cloza-100 Tablet ?

Can I stop taking Cloza-100 Tablet if I feel well?

Does Cloza-100 Tablet increase the risk of infections?

Does Cloza-100 Tablet cause orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing)?

Does Cloza-100 Tablet cause irregular heartbeat?

Why do I need to get regular blood tests while taking Cloza-100 Tablet ?

Can I drink coffee or energy drinks while taking Cloza-100 Tablet ?

What should I do if I forget to take my medicine for more than two days?

Will Cloza-100 Tablet make me feel sleepy or dizzy?

Can I stop taking Cloza-100 Tablet if my symptoms are gone?

How does Cloza-100 Tablet affect my weight and blood sugar?

How long does it take for Cloza-100 Tablet to show results?

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