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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Clozabest 100 Tablet is used to treat schizophrenia. Additionally, it is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. It contains Clozapine, which helps in improving mood, behaviour and thoughts. It may cause side effects such as tachycardia (fast heartbeat), dizziness, headache, tremor, sweating, dry mouth, nausea, constipation and visual disturbances. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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rxMedicinePrescription drug

Whats That

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Composition :

CLOZAPINE-100MG

Manufacturer/Marketer :

Arinna Lifesciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Clozabest 100 Tablet

Clozabest 100 Tablet is used to treat schizophrenia. Additionally, Clozabest 100 Tablet is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. Schizophrenia is a medical condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused.

Clozabest 100 Tablet contains ‘Clozapine’, which works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin. Thus, it helps in improving mood, behaviour and thoughts.

You are advised to take Clozabest 100 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Clozabest 100 Tablet may cause side effects such as tachycardia (fast heartbeat), dizziness, headache, tremor, sweating, dry mouth, nausea, constipation and visual disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Clozabest 100 Tablet suddenly, as it might cause withdrawal symptoms. Consult your doctor if you are pregnant. Do not take Clozabest 100 Tablet if you are breastfeeding, as it may pass into breastmilk. Avoid driving as Clozabest 100 Tablet may cause drowsiness and dizziness. Clozabest 100 Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Clozabest 100 Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Clozabest 100 Tablet

Treatment of Schizophrenia

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush it.Orodispersible/Mouth dissolving tablet: Check the label for directions before use. Place the tablet in the mouth and allow it to dissolve.

Medicinal Benefits

Clozabest 100 Tablet belongs to a group of medicines called antipsychotics. Clozabest 100 Tablet is used to treat schizophrenia and to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. Clozabest 100 Tablet works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin, thereby helping in improving mood, behaviour and thoughts. Clozabest 100 Tablet is used to treat schizophrenia when other antipsychotic drugs are ineffective or have caused severe adverse effects. Clozabest 100 Tablet is also used to treat psychotic disorders in patients with Parkinson’s disease when standard treatments have failed.

How Clozabest 100 Tablet Works

Clozabest 100 Tablet contains ‘Clozapine’, which works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin. Thus, it helps in improving mood, behaviour and thoughts.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Clozabest 100 Tablet

Do not take more than the prescribed dose of Clozabest 100 Tablet as it may cause overdose. The symptoms of overdose include sedation, fast heart rate, high blood pressure, respiratory depression or failure, delirium (serious changes in mental abilities), coma or excess saliva production. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Clozabest 100 Tablet if you are allergic to any of its contents if you have galactose intolerance, total lactase deficiency, glucose-galactose malabsorption, low number of white blood cells or if you are taking medicines that can cause low levels of white blood cells, bone marrow disorder, epilepsy, circulatory collapse (pronounced fall in blood pressure that can lead to unconsciousness), brain disorders, severe kidney disease, heart disease, liver disease with jaundice, liver failure or paralytic ileus (small intestine disorder). Inform your doctor if you have a low number of white blood cells or platelet count, orthostatic hypotension, epilepsy, enlarged prostate or difficulty urinating, glaucoma, severe constipation, diabetes, heart, liver or kidney problems. Consult your doctor if you are pregnant. Do not take Clozabest 100 Tablet if you are breastfeeding, as it may pass into breastmilk.

Drug-Drug Interactions

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ClozapineCisapride
Critical
ClozapineMetoclopramide
Critical

Drug-Drug Interactions

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ClozapineCisapride
Critical
How does the drug interact with Clozabest 100 Tablet:
When Clozabest 100 Tablet is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Clozabest 100 Tablet with Cisapride there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ClozapineMetoclopramide
Critical
How does the drug interact with Clozabest 100 Tablet:
Co-administration of Metoclopramide with Clozabest 100 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Clozabest 100 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
ClozapinePotassium citrate
Critical
How does the drug interact with Clozabest 100 Tablet:
Taking Clozabest 100 Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Co-administration of Potassium citrate with Clozabest 100 Tablet is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ClozapineSparfloxacin
Critical
How does the drug interact with Clozabest 100 Tablet:
When Clozabest 100 Tablet is taken with Sparfloxacin, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Clozabest 100 Tablet with Sparfloxacin there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ClozapinePimozide
Critical
How does the drug interact with Clozabest 100 Tablet:
When Clozabest 100 Tablet is taken with Pimozide, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Clozabest 100 Tablet with Pimozide there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ClozapineRopinirole
Critical
How does the drug interact with Clozabest 100 Tablet:
When Ropinirole is taken with Clozabest 100 Tablet, it may not work as well.

How to manage the interaction:
Taking Ropinirole with Clozabest 100 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.
ClozapineFlibanserin
Critical
How does the drug interact with Clozabest 100 Tablet:
When Flibanserin and Clozabest 100 Tablet are taken together, may increase side effects.

How to manage the interaction:
There may be a possibility of interaction between Clozabest 100 Tablet and Flibanserin, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, drowsiness, fatigue, and difficulty concentrating, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClozapineKetoconazole
Severe
How does the drug interact with Clozabest 100 Tablet:
Taking Ketoconazole and Clozabest 100 Tablet together can increase the chance of a serious irregular heart rhythm.

How to manage the interaction:
Taking Ketoconazole and Clozabest 100 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue the medications without consulting a doctor.
ClozapineAlfuzosin
Severe
How does the drug interact with Clozabest 100 Tablet:
Taking Clozabest 100 Tablet with Alfuzosin can increase the risk of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Alfuzosin with Clozabest 100 Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms like vomiting, dizziness, difficulty breathing, or palpitations, consult the doctor. Do not stop using any medications without a doctor's advice.
ClozapineThiotepa
Severe
How does the drug interact with Clozabest 100 Tablet:
Combining Thiotepa with Clozabest 100 Tablet can increase the risk of infection.

How to manage the interaction:
Although taking Thiotepa and Clozabest 100 Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include fruits, vegetables, and fibre-rich food in your diet.
  • Cut down on sugars, salts and saturated fats.
  • Drink enough fluids to stay hydrated.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

Clozabest 100 Tablet Substitute

Substitutes safety advice
  • Sizopin 100 Tablet 10's

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  • Skizoril 100 Tablet 10's

    by Others

    8.51per tablet
  • Alkepin ODT 100 Tablet 10's

    by AYUR

    8.51per tablet
  • Cipin-100 Tablet 10's

    by Others

    8.51per tablet
  • Zaporil 100 Tablet 10's

    by Others

    8.51per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Clozabest 100 Tablet as it may cause increased drowsiness.

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Pregnancy

Caution

Clozabest 100 Tablet belongs to pregnancy category B. Please consult your doctor if you are pregnant before taking this medicine; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Clozabest 100 Tablet is not recommended for use during breastfeeding.

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Driving

Unsafe

Clozabest 100 Tablet causes tiredness, dizziness and vision problems. Do not drive or operate machinery if you experience these symptoms.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Clozabest 100 Tablet should not be given to children as safety and effectiveness have not been established.

Have a query?

FAQs

Clozabest 100 Tablet is used to treat schizophrenia. Additionally, it is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders.

Clozabest 100 Tablet works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin, thereby improving mood, behaviour and thoughts.

Do not discontinue Clozabest 100 Tablet without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking Clozabest 100 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Clozabest 100 Tablet .

Clozabest 100 Tablet may cause agranulocytosis (low levels of white blood cells), making you more prone to infections. Consult your doctor immediately if you experience flu-like symptoms, sore throat or fever.

Dry mouth could be a side-effect of Clozabest 100 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Orthostatic hypotension could be a side-effect of Clozabest 100 Tablet . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.

Clozabest 100 Tablet may cause tachycardia (fast heartbeat). Talk to your doctor if you experience irregular or fast heartbeat even at rest, chest pain, unexplained tiredness or breathing problems.

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take your regular dose. Please don't take a double dose to make up for a missed one.

Country of origin

INDIA

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - CLO1778

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