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  3. Cobix 200 Capsule 10's

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Cobix 200 Capsule 10's, Pack of 10 CAPSULES
Cobix 200 Capsule 10's, Pack of 10 CAPSULES
Cobix 200 Capsule 10's, Pack of 10 CAPSULES
Cobix 200 Capsule 10's, Pack of 10 CAPSULES
Cobix 200 Capsule 10's, Pack of 10 CAPSULES
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cobix 200 Capsule is used to reduce pain and swelling in muscles and joints. It treats painful conditions of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck), and menstrual pain. It contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme that causes pain and inflammation in the body. Thereby, it helps relieve pain and swelling. It may cause side effects such as indigestion, stomach pain, diarrhoea, oedema, and flatulence.

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Composition :

CELECOXIB-200MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Cobix 200 Capsule

Cobix 200 Capsule is used to reduce pain and swelling in muscles and joints. It treats painful conditions of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck), and menstrual pain. Arthritis is a condition that causes swelling and pain in one or more joints, worsening over time.

Cobix 200 Capsule contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme that causes pain and inflammation in the body. It thereby helps relieve pain and swelling associated with various types of arthritis, spondylitis, low back pain, and menstrual pain.

Your doctor will advise you on how often you take this medicine based on your medical condition. In some cases, you may experience indigestion, stomach pain, diarrhoea, oedema, and flatulence. Most of the side effects of Cobix 200 Capsule do not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Cobix 200 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Cobix 200 Capsule . Do not consume alcohol with Cobix 200 Capsule as it may increase the risk of stomach bleeding. Cobix 200 Capsule may cause an increased risk of severe heart problems like myocardial infarction and stroke, which can be fatal.

Cobix 200 Capsule should not be used by a patient who has undergone recent heart bypass surgery or will undergo it. Cobix 200 Capsule increases the risk of severe gastrointestinal conditions like bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.

Uses of Cobix 200 Capsule

Cobix 200 Capsule is used for joint pain relief and menstrual cramps. The detailed uses of Cobix 200 Capsule are as follows:

  • Relieve pain and inflammation in arthritis: Cobix 200 Capsule is primarily used to treat osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It works by blocking the action of COX-2 enzymes, which are responsible for inflammation and pain in joints and muscles.
  • Manage acute pain and menstrual discomfort: Cobix 200 Capsule is effective in reducing short-term pain such as post-surgical discomfort or menstrual cramps. Its anti-inflammatory action helps ease swelling and tenderness, providing targeted relief without the sedative effects of opioids.

Health Queries

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Gatheya is a term used in some regions to describe scaly, dry patches of skin, often associated with fungal infections, eczema, or psoriasis. It may appear as rough, thickened, or flaky skin, sometimes itchy or inflamed. The exact cause needs to be evaluated by a doctor or dermatologist, as treatment depends on the underlying condition. For fungal infections, antifungal creams or medications may be prescribed; for eczema or psoriasis, moisturisers, steroid creams, or other specific therapies may be recommended. Maintaining proper skin hygiene, keeping the area dry, and avoiding irritants can help prevent worsening. A dermatologist's consultation is essential to confirm the diagnosis and provide the appropriate treatment.
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Rheumatoid arthritis is a chronic autoimmune condition that requires careful medical management. Oral medications may be prescribed to help reduce inflammation, control symptoms, and slow joint damage, but the choice of medicine, dosage, and monitoring must be determined by a rheumatologist. Self-medicating can be dangerous, as these treatments can affect the immune system and may cause serious side effects. It is essential to consult your doctor to develop a personalised treatment plan that is safe and effective for your condition.
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Complete stiffness in all joints with inability to move is a medical emergency. You should seek immediate care at a hospital or call emergency services. This could be caused by severe musculoskeletal or neurological disorders, advanced arthritis, spinal cord injury, severe infections, or metabolic problems. Doctors will perform urgent blood tests, imaging, and neurological examinations to determine the cause and begin appropriate treatment. Prompt medical attention is critical to prevent permanent disability or life-threatening complications.
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Persistent shoulder pain despite long-term treatment requires re-evaluation by your doctor or a rheumatologist, especially since your RA factor is negative. Being RA factor negative does not rule out other types of arthritis, tendon or joint injuries, or autoimmune conditions. Your doctor may recommend imaging, blood tests, or other assessments to determine the underlying cause and whether your current medication is appropriate. All arthritis medications can have potential side effects, which vary depending on the type, dose, and duration. Do not change or stop your medication on your own. Discussing your symptoms, treatment effectiveness, and any side effects with your doctor is essential to ensure safe and effective management.
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Rheumatoid arthritis (RA) and osteoarthritis (OA) are both conditions that affect the joints, but they have different causes and characteristics. RA is an autoimmune disease in which the immune system attacks the joint lining, causing inflammation, pain, and swelling, often affecting multiple joints symmetrically. OA is a degenerative joint disease caused by the wear and tear of cartilage over time, leading to stiffness, pain, and reduced mobility, typically in weight-bearing joints such as the knees and hips. While both conditions cause joint pain and can limit daily activities, RA primarily involves inflammation and systemic effects, whereas OA mainly results from mechanical degeneration. In some cases, a person may have features of both, especially as they age. Management and treatment strategies differ, so it is essential to consult a doctor for an accurate diagnosis and individualised care.

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Directions for Use

  • Cobix 200 Capsule can be taken with or without food, but taking it with food helps reduce stomach upset.
  • It is advised to take Cobix 200 Capsule once or twice daily, or as directed by your doctor, at the same time each day for best results.
  • Swallow Cobix 200 Capsule as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Cobix 200 Capsule provides effective relief from pain and inflammation associated with arthritis and other musculoskeletal conditions.
  • Helps manage symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
  • Reduces stiffness, swelling, and joint discomfort to improve mobility.
  • Offers pain relief in acute conditions such as menstrual cramps and postoperative pain.
  • Helps improve quality of life by enabling better physical activity and comfort.
  • Provides long-lasting pain control with convenient dosing.

How Cobix 200 Capsule Works

Cobix 200 Capsule contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme that causes pain and inflammation in the body. It thereby helps relieve pain and swelling associated with various types of arthritis, spondylitis, low back pain, and menstrual pain.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Cobix 200 Capsule
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

What if I have taken an overdose of Cobix 200 Capsule

Do not take more than the prescribed dose of Cobix 200 Capsule as it may cause an overdose. The symptoms of overdose include stomach pain, nausea, vomiting, lack of energy, drowsiness, bloody or black tarry stools, vomiting material that is bloody or looks like coffee grounds, loss of consciousness and difficulty breathing or swallowing. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Cobix 200 Capsule if you are allergic to any of its ingredients.
  • Cobix 200 Capsule may cause an increased risk of severe heart problems like myocardial infarction and stroke, which can be fatal.
  • It should not be used by a patient who has undergone recent heart bypass surgery or will undergo it.
  • Cobix 200 Capsule increases the risk of severe gastrointestinal conditions like bleeding, ulceration and perforation of the stomach or intestines, which can be fatal.
  • Elderly patients are at greater risk of gastrointestinal bleeding, so the doctor can limit their dose.
  • Cobix 200 Capsule is not recommended for pregnant women, especially in the third trimester, as it may cause harm to the unborn baby (fetus). Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Cobix 200 Capsule .
  • Do not consume alcohol with Cobix 200 Capsule as it may increase the risk of stomach bleeding or ulcer.
  • If you experience weight loss, diarrhoea, pain or vomiting, please stop taking Cobix 200 Capsule and consult a doctor immediately. These might be signs of worsening, Crohn’s disease, or ulcerative colitis (swelling in the digestive tract).

Drug-Drug Interactions

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CelecoxibThioridazine
Critical
CelecoxibCidofovir
Critical

Drug-Drug Interactions

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CelecoxibThioridazine
Critical
How does the drug interact with Cobix 200 Capsule:
Taking thioridazine and Cobix 200 Capsule may increases the blood levels of thioridazine which may cause irregular heart rhythm.

How to manage the interaction:
Taking Cobix 200 Capsule with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without first talking to your doctor.
CelecoxibCidofovir
Critical
How does the drug interact with Cobix 200 Capsule:
Co-administration of Cidofovir with Cobix 200 Capsule can increase the risk of kidney problems.

How to manage the interaction:
Taking Cobix 200 Capsule with Cidofovir is not recommended, please consult your doctor before taking it. However, consult the doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to a doctor.
CelecoxibMeloxicam
Critical
How does the drug interact with Cobix 200 Capsule:
Co-administration of Cobix 200 Capsule with Meloxicam can increase the risk or severity of bleeding and ulcers of the stomach lining leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Cobix 200 Capsule is not recommended, but can be taken together if prescribed by a doctor. However, consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a dcovct
CelecoxibKetorolac tromethamine
Critical
How does the drug interact with Cobix 200 Capsule:
Taking Ketorolac with Cobix 200 Capsule can increase the risk of gastrointestinal bleeding and ulcers,

How to manage the interaction:
Taking Ketorolac tromethamine with Cobix 200 Capsule is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
CelecoxibKetorolac
Critical
How does the drug interact with Cobix 200 Capsule:
Taking Ketorolac with Cobix 200 Capsule can increase the risk of side effects such as gastrointestinal bleeding and ulcers.

How to manage the interaction:
Taking Cobix 200 Capsule with Ketorolac is not recommended, but can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
CelecoxibEliglustat
Critical
How does the drug interact with Cobix 200 Capsule:
Taking eliglustat with Cobix 200 Capsule can significantly increase the blood levels of eliglustat. This may increase the risk of serious side effects.

How to manage the interaction:
Taking Cobix 200 Capsule with Eliglustat is not recommended, but can be taken together if prescribed by a doctor. However, consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate and weak pulse. Do not discontinue any medications without consulting a doctor.
CelecoxibAdefovir dipivoxil
Severe
How does the drug interact with Cobix 200 Capsule:
Taking Cobix 200 Capsule with Adefovir dipivoxil may increase risk of kidney problems.

How to manage the interaction:
Although taking Cobix 200 Capsule and Adefovir dipivoxil together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
CelecoxibEverolimus
Severe
How does the drug interact with Cobix 200 Capsule:
Taking everolimus with Cobix 200 Capsule may increase risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Everolimus and Cobix 200 Capsule, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, weight loss, swelling, muscle cramps, weakness, dizziness, confusion, or an irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
CelecoxibTeriflunomide
Severe
How does the drug interact with Cobix 200 Capsule:
Taking Teriflunomide with Cobix 200 Capsule affects the liver and may increase the risk of liver problems.

How to manage the interaction:
Although taking Cobix 200 Capsule and Teriflunomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
CelecoxibDiclofenac
Severe
How does the drug interact with Cobix 200 Capsule:
Co-administration of Diclofenac with Cobix 200 Capsule may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between diclofenac and Cobix 200 Capsule, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce tissue inflammation.
  • Do not engage in strenuous exercise, as it may worsen joint pain in arthritis. Instead, you can do stretching, low-impact aerobic exercise like walking on a treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • For chronic conditions such as arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fish are enriched with omega-3 fatty acids that help reduce levels of a chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammatory conditions. Try to sit as little as possible, and only for a short time (10-15 min). Use a back support, such as a rolled-up towel, at the back of your curve to minimise pain. Keep your knees and hips at a right angle. Additionally, you can use a footrest if needed.

Habit Forming

No

Therapeutic Class

ANALGESICS

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Alcohol

Unsafe

Taking alcohol, along with Cobix 200 Capsule , can increase the chances of gastrointestinal bleeding and kidney damage.

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Pregnancy

Unsafe

Cobix 200 Capsule is a category C pregnancy drug. It should not be given during pregnancy, especially during the last trimester, as it is known to cause fetal deformities.

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Breast Feeding

Unsafe

Cobix 200 Capsule is not recommended for breastfeeding women.

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Driving

Caution

Cobix 200 Capsule is not known to cause drowsiness, but if you feel sleepy, please do not operate or drive any machinery.

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Liver

Consult your doctor

If you have had a history of any liver-related diseases, please consult a doctor before taking medicine.

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Kidney

Consult your doctor

If you have had a history of any kidney-related diseases, please consult a doctor before taking medicine.

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Children

Caution

Cobix 200 Capsule is not recommended for children under 2 years old. For children aged 2 years or older, take it at the dose and duration prescribed by your doctor.

FAQs

Cobix 200 Capsule is used to reduce pain and swelling in muscles and joints. It treats pain in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness of the spine), cervical spondylosis (wear and tear of spinal discs in the neck), and menstrual pain.

Cobix 200 Capsule contains Celecoxib, which works by blocking the action of the pain-inducing chemical messenger cyclo-oxygenase (COX) enzyme in the body, which is involved in producing certain chemical substances, such as prostaglandins, that cause pain and swelling. It thereby helps relieve pain and swelling associated with different types of arthritis.

Yes, Cobix 200 Capsule can be used to treat menstrual cramps. Cobix 200 Capsule is a painkiller that decreases pain and inflammation-inducing chemical messenger known as prostaglandin (PG) production in the body involved in making the uterus (womb) contract during periods.

Arthritis is a chronic condition of the joints characterised by pain and inflammation. Cobix 200 Capsule does not cure arthritis, but it relieves symptoms of arthritis, such as joint pain, swelling, and stiffness.

Yes, Cobix 200 Capsule may increase the risk of heart problems such as heart attack and stroke, especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Cobix 200 Capsule . However, it is recommended to take Cobix 200 Capsule at the prescribed dose and for the prescribed duration. It should not be used by the patient who has had recent heart bypass surgery (coronary artery bypass graft - CABG).

No, you are not recommended to take Cobix 200 Capsule with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so the dose can be adjusted appropriately to ensure safe use.

You should avoid using Cobix 200 Capsule if you have gastrointestinal ulcer/bleeding, have undergone planned heart bypass surgery or are pregnant for more than 30 weeks.

Cobix 200 Capsule may reduce the blood pressure-lowering effects of certain blood pressure drugs; you are advised to contact your doctor so the dose can be adjusted appropriately to ensure safe use.

Country of origin

India

Manufacturer/Marketer address

52, Industrial Area Phase-1, Chandigarh.
Other Info - COB0014

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 19, 2025 | 8:23 AM IST

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Reference

  1. https://medlineplus.gov/druginfo/meds/a699022.html
  2. https://www.medicines.org.uk/emc/files/pil.2945.pdf

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