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compositionComposition:ACEBROPHYLLINE-200MG+MONTELUKAST-10MG
prescription
Prescription Medicine
info
Coekastle-A Tablet 10's

Coekastle-A Tablet is used to treat and prevent respiratory disorders like asthma attacks, chronic obstructive pulmonary diseases (COPD) and allergic rhinitis (hay fever). It contains Acebrophylline and Montelukast, which work by relaxing muscles and widening the airways of the lungs.

It may cause common side effects such as headache, sore throat/cough, vomiting, upset stomach, diarrhea, heartburn, runny nose, rash, itching, drowsiness, restlessness, abdominal pain (stomach pain), and nasal inflammation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ACEBROPHYLLINE-200MG+MONTELUKAST-10MG

Manufacturer/Marketer :

Koye Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Coekastle-A Tablet

Coekastle-A Tablet is a combination medicine prescribed to manage chronic respiratory conditions such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It helps by relieving chest tightness, wheezing, shortness of breath, and persistent coughing associated with these conditions. By keeping the airways open and thinning thick mucus, this medication makes breathing significantly easier for patients suffering from long-term respiratory difficulties.

To achieve the best results, take Coekastle-A Tablet regularly and exactly as directed by your doctor. Depending on your condition and the prescribed formulation, it is commonly taken once daily in the evening, although your doctor may recommend a different schedule. It can be taken with or without food. Alongside taking this medicine, implementing simple lifestyle changes, such as drinking plenty of warm fluids to help loosen mucus and keeping your living space free from dust and allergens, can greatly improve your treatment outcomes.

While taking Coekastle-A Tablet , some people may experience mild side effects, such as a mild stomach upset, headache, or slight drowsiness. These issues usually resolve on their own as your body adjusts to the medicine. However, you must consult your doctor immediately if you experience severe symptoms, such as an intense skin rash, yellowing of your eyes or skin, or sudden and unusual changes in your mood or behaviour.

Do not take this medicine if you have a known allergy to any of its components. Before starting Coekastle-A Tablet , you must talk to your doctor if you have a history of liver damage, kidney disease, active stomach ulcers, or heart problems. Your doctor will evaluate whether this medicine is safe for you based on your medical history.

Coekastle-A Tablet can interact with other substances, so you should inform your doctor about all the medications you are currently taking. For instance, taking it with certain epilepsy drugs or antibiotics can affect how the medicine works in your body, while consuming alcohol may increase drowsiness. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor before starting this medicine to ensure your safety.

Uses of Coekastle-A Tablet

Coekastle-A Tablet is used to manage chronic respiratory conditions. It is commonly prescribed for: 

  • Asthma: Coekastle-A Tablet helps prevent and manage asthma symptoms by reducing inflammation and narrowing in the lung airways, thereby preventing sudden shortness of breath and wheezing.
  • Chronic Obstructive Pulmonary Disease (COPD): It eases long-term breathing difficulties in COPD patients by relaxing the lung muscles and easing the clearance of thick, obstructive mucus.
  • Bronchitis: It relieves symptoms of chronic bronchitis by reducing swelling in the bronchial tubes and thinning excess phlegm, which makes coughing less painful and more productive.

Key Benefits

Coekastle-A Tablet helps improve breathing by reducing airway inflammation, relaxing the airways, and clearing excess mucus. Its benefits include:

  • Improves Breathing: Helps open the airways and reduce inflammation, making breathing easier.
  • Reduces Mucus Build-Up: Thins and loosens thick mucus, making it easier to cough out and helping keep the airways clear.
  • Prevents Breathing Flare-Ups: Regular use helps reduce the frequency of asthma attacks and other respiratory symptom flare-ups.
  • Relieves Persistent Cough: Helps reduce coughing associated with excess mucus and airway inflammation, promoting more restful sleep.
  • Supports Daily Activities: Better control of respiratory symptoms helps improve exercise tolerance and makes everyday activities more comfortable.
Side effects of Coekastle-A Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Maintain a gentle oral hygiene routine by brushing your teeth twice daily with a soft-bristled toothbrush and fluoride toothpaste, and flossing once a day to remove trapped food particles.
  • Modify your diet to limit sugary and acidic foods and beverages, and opt for soft, easy-to-chew foods to reduce discomfort and promote healing.
  • Manage pain and discomfort with over-the-counter medication, cold compresses, and warm salt water rinses as needed.
  • Adopt healthy lifestyle habits, including quitting smoking and tobacco use, staying hydrated, and stimulating saliva production with sugar-free gum to support overall health and well-being.
  • Avoid extreme temperatures and irritants, such as extremely hot or cold foods and drinks, to prevent further discomfort and promote a smooth recovery.
  • Get ample rest; this helps your stomach to settle.
  • Eat soft and easy-to-digest foods like white rice, bananas, crackers and apple sauce.
  • Include probiotics-rich food like yoghurt, kefir, or miso, as they help maintain gut functioning.
  • Wash your hands properly before preparing/eating food and after using the toilet.
  • Drink water, broth or diluted fruit juice to replace electrolytes and lost fluids.
  • Avoid caffeine, alcohol, high-fat, fried and fast foods, as well as sweetened beverages.

Directions for Use

  • Coekastle-A Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Coekastle-A Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Coekastle-A Tablet Works

Coekastle-A Tablet contains acebrophylline and montelukast, which work together to improve lung function. Acebrophylline is a bronchosecretolytic medicine that helps thin and loosen thick mucus, making it easier to clear from the airways. It also has mild bronchodilator and anti-inflammatory effects, helping the airways remain more open. However, it is not a substitute for fast-acting bronchodilators such as salbutamol during sudden breathing attacks. Montelukast is a selective leukotriene receptor antagonist. It blocks the action of leukotrienes, natural chemicals that cause airway inflammation, swelling, and tightening. By blocking these chemicals, montelukast helps reduce inflammation and prevent narrowing of the airways. Together, these actions help improve mucus clearance, reduce airway inflammation, keep the airways more open, and make breathing easier.
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Alcohol

Unsafe

Avoid drinking alcohol while taking Coekastle-A Tablet to avail the maximum benefits and prevent the worsening of side-effects.

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Pregnancy

Consult your doctor

Coekastle-A Tablet is recommended to use with caution and under doctor's supervision during pregnancy. Please consult your doctor if you are planning to conceive or already pregnant before starting Coekastle-A Tablet .

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Breast Feeding

Consult your doctor

There is limited data on how Coekastle-A Tablet affects breastfeeding. Please consult your doctor before starting Coekastle-A Tablet .

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Driving

Caution

Do not drive or operate machinery if you experience drowsiness or difficulty in concentrating while using Coekastle-A Tablet . Coekastle-A Tablet may affect your ability to drive. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Coekastle-A Tablet should be used with caution in patients with liver diseases. Let your doctor know if you have any history of hepatic impairment before taking Coekastle-A Tablet .

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Kidney

Caution

Coekastle-A Tablet should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases.

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Children

Consult your doctor

Coekastle-A Tablet is not recommended for use for children less than two years of age. The dose may have to be adjusted by your doctor depending upon the condition of the child's disease and age.

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Heart

Caution

Coekastle-A Tablet should be used in cardiac patients with caution.

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Geriatrics

Caution

Coekastle-A Tablet should be given to elderly patients only if prescribed by a doctor. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Coekastle-A Tablet

If you suspect an overdose or have accidentally taken more than your prescribed dose, seek immediate medical attention or visit the nearest hospital emergency room. Do not wait for symptoms of toxicity to appear.

Diet & Lifestyle Advise

  • Stay Well-Hydrated: Drink plenty of water and warm fluids throughout the day to help thin mucus and make it easier to clear from your lungs.
  • Avoid Respiratory Triggers: Stay away from cigarette smoke, dust, pollen, strong perfumes, chemical fumes, and other known allergens or irritants.
  • Practice Breathing Exercises: Perform breathing exercises, such as diaphragmatic or pursed-lip breathing, if recommended by your healthcare provider to improve lung function.
  • Reduce Allergen Exposure: Keep your home well-ventilated and reduce exposure to dust mites by washing bedding regularly and keeping living areas clean.

Have a query?

How Soon It Starts Working

  • The time required for Coekastle-A Tablet to start to work: The time required for Coekastle-A Tablet to start to work is 1 hour after administration.
  • The time for which the effects of Coekastle-A Tablet last: The effect of Coekastle-A Tablet lasts for 24 hours.

What if you forget to take Coekastle-A Tablet

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

•Store Coekastle-A Tablet tablets in a cool, dry place at room temperature, ideally between 15°C and 30°C. •Keep the tablets in their original blister packaging until you are ready to take them, protecting them from direct sunlight, high heat, and moisture.

Drug Warnings

  • Not for Sudden Asthma Attacks: This medicine is intended for long-term control and prevention. Always carry your prescribed rescue inhaler for sudden breathing difficulties.
  • Monitor Mood and Behaviour: Montelukast carries a regulatory boxed warning about serious neuropsychiatric side effects. Contact your doctor immediately if you notice changes in mood, anxiety, agitation, sleep disturbances, depression, suicidal thoughts, or unusual behaviour while taking this medicine.
  • Use Caution During Activities: Avoid driving or operating machinery until you know how Coekastle-A Tablet affects you, as it may cause dizziness or drowsiness.
  • Do Not Stop Treatment Abruptly: Continue taking the medicine as prescribed, even if you feel well. Do not stop treatment without consulting your doctor, as your symptoms may return or worsen.

Drug-Drug Interactions

verifiedApollotooltip

Some medicines may affect how Coekastle-A Tablet works or increase the risk of side effects. Tell your doctor about all the medicines you are taking, including 

  • Seizure Medications: Taking this medicine alongside drugs like phenobarbital or phenytoin can speed up its clearance from your body, potentially making Coekastle-A Tablet less effective.
  • Certain Antibiotics: Medications like erythromycin may raise the levels of this medicine in your bloodstream, which can increase the risk of experiencing side effects.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

Certain foods and drinks may affect how Coekastle-A Tablet works or increase the risk of side effects:

  • Caffeine: Limit your intake of coffee, strong tea, energy drinks, and other highly caffeinated products while taking Coekastle-A Tablet . Acebrophylline contains a theophylline derivative, and consuming excessive caffeine may increase stimulant effects such as restlessness, tremors, palpitations, or a rapid heartbeat. 
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[RESPIRATORY STIMULANTS]

FAQs

Coekastle-A Tablet is used to treat and prevent respiratory disorders like asthma attacks, chronic obstructive pulmonary diseases (COPD)Â and allergic rhinitis (hay fever).
Coekastle-A Tablet consists of Acebrophylline and Montelukast. Acebrophylline is a bronchodilator that works by relaxing muscles and widening the airways of the lungs. Montelukast is a leukotriene receptor antagonist that blocks leukotrienes (chemicals released in response when a body comes in contact with an allergen) and reduces inflammation and swelling in the nose.
Please take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
Therapy with leukotriene receptor antagonists like Montelukast may worsen the symptoms of psychotic events in patients with a history of mental illness. Careful administration and monitoring are essential before taking Coekastle-A Tablet in patients with neuropsychiatric disorders. Please consult your doctor before taking Coekastle-A Tablet if you have been diagnosed or have a history of mental illness like depression, seizures (fits) etc.
It is essential to let your doctor know if you have any history of heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, stomach ulcers and viral infections before taking Coekastle-A Tablet .
No, you are advised not to take atenolol while using Coekastle-A Tablet because atenolol opposes the action of Coekastle-A Tablet as it narrows the airways and causes breathing difficulty.
Swallow the tablet whole with a drink of water. Do not chew it. Coekastle-A Tablet can be taken with or without food. The dosage and duration depend on individual factors.
Taking more than the recommended dosage does not provide additional pain relief and can increase the risk of adverse effects.
The common side effects of Coekastle-A Tablet include headache, sore throat/cough, vomiting, upset stomach, diarrhoea, heartburn, runny nose, rash, itching, drowsiness, restlessness, abdominal pain (stomach pain), and nasal inflammation. Most of these side effects of Coekastle-A Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please contact your doctor.
Store in a cool and dry place away from sunlight. Keep out of sight and reach of children. To help protect the environment, avoid throwing away any medicines via wastewater or household waste. Ask your doctor or pharmacist regarding the disposal of medicines.
Coekastle-A Tablet is a combination of two medicines: Acebrophylline (bronchodilator) and Montelukast (leukotriene receptor antagonist).
No, Coekastle-A Tablet is not designed to provide immediate relief during a sudden, acute asthma attack. It is a long-term controller medication that must be taken daily to prevent symptoms. For quick relief during an attack, you should always use your prescribed quick-relief rescue inhaler. Talk to your doctor if you do not have a rescue inhaler.
Your doctor will instruct you on the best timing, but Coekastle-A Tablet is most commonly taken once daily in the evening. Taking it at the same time every day helps keep a stable level of the medicine in your body. Talk to your doctor to confirm your specific dosing schedule.
It is highly recommended to avoid or significantly limit alcohol consumption while taking Coekastle-A Tablet . Alcohol can worsen side effects like drowsiness, dizziness, and stomach irritation. Talk to your doctor if you have questions about consuming alcohol while on this medication.
If you experience dizziness or sleepiness, sit or lie down immediately. Avoid driving, riding a bicycle, or operating any machinery until these symptoms pass. If the drowsiness is severe or does not improve over time, talk to your doctor.
The safety of Coekastle-A Tablet during pregnancy and breastfeeding has not been fully established. It should only be used if the potential benefits outweigh the risks and it is directly prescribed by your healthcare provider. Talk to your doctor to evaluate your options safely.
No, you should not stop taking this medicine on your own. Coekastle-A Tablet is a preventative maintenance medication that needs to be taken continuously to keep your airways open and healthy. Stopping it early may cause your respiratory symptoms to return or worsen. Talk to your doctor before making any changes.
Yes, in rare cases, one of the active components in this medicine is associated with neuropsychiatric side effects, including irritability, anxiety, sleep problems, depression, or vivid dreams. If you or your family notice any unusual behaviour or mood changes, contact your doctor right away.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Montelukast Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. CiplaMed Clinical Compendium. Printpdf Product Specification Guide. Mumbai, India: Cipla; 2024. [Accessed on 02 Jun. 2026] Check here
  3. Electronic Medicines Compendium (EMC). Pil.1243 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  5. Montelukast sodium [EMC Label]. 2018. [Accessed on 22 Apr. 2019] Check here
  6. Pozzi E Acebrophylline: An airway mucoregulator and anti-inflammatory agent. Monaldi Arch Chest Dis. 2007;67(2):106-15 Check here
  7. Montelukast Montelukast. 1998. [Accessed on 22 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

A-10, 3rd Floor, Art Guild House, Phoenix Market City Annexe, LBS Marg, Kurla (West), Mumbai - 400070
Other Info - COE0071

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