apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
Cofdex Cough Syrup 100 ml

Cofdex Cough Syrup 100 ml is used to treat dry cough. It works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. This medicine may sometimes cause side effects such as dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, and restlessness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

Read more
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
coupon
coupon
Extra 10% Off with Bank Offers

More about the Product

Composition :

CHLORPHENIRAMINE-2MG+DEXTROMETHORPHAN-10MG+PHENYLEPHRINE-5MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Cofdex Cough Syrup 100 ml

Cofdex Cough Syrup 100 ml belongs to a class of antiarrhythmic medicines used to treat irregular heartbeats (arrhythmias) and protect the heart during the early stages after a heart attack (myocardial infarction), which occurs when the heart muscle does not receive enough blood and oxygen.

Cofdex Cough Syrup 100 ml contains Atenolol, which works by blocking certain natural substances in the heart and blood vessels. This slows the heart rate and reduces blood pressure, lowering the risk of heart attack, stroke, and kidney problems.

Cofdex Cough Syrup 100 ml is administered by a healthcare professional; do not self-administer. Some people may experience cold hands or feet, diarrhoea, nausea, or tiredness. These side effects usually resolve over time, but consult your doctor if they persist or worsen.

Before using Cofdex Cough Syrup 100 ml, inform your doctor if you have any allergies to its ingredients, are pregnant, planning pregnancy, or breastfeeding. For pediatric use, the dose and duration must be determined by a paediatrician and administered under strict medical supervision. Additionally, provide your doctor with your complete medical history and details of any current medications to minimise the risk of adverse effects or drug interactions.

Uses of Cofdex Cough Syrup 100 ml

Cofdex Cough Syrup 100 ml is used to treat dry cough. The detailed uses of Cofdex Cough Syrup 100 ml are as follows:

  • Cough Relief: Cofdex Cough Syrup 100 ml is designed to provide cough relief, especially for dry coughs, by utilising its antitussive properties to calm throat irritation and reduce the urge to cough.
  • Allergy Relief: Cofdex Cough Syrup 100 ml can help to alleviate allergy symptoms like a runny nose and sneezing, offering relief for individuals who experience seasonal allergic reactions.
  • Soothing Sore Throat: Cofdex Cough Syrup 100 ml helps to calm a sore throat caused by coughing or irritation, making swallowing easier and reducing throat discomfort.
  • Decongestant: Cofdex Cough Syrup 100 ml contains Phenylephrine, a decongestant that reduces nasal congestion by shrinking swollen blood vessels in the nasal passages.

Health Queries

I have had a cough for the past 10 days. I already took Cofdex syrup (2 bottles) and am currently using Broxyl AP syrup, but I am not getting relief. Do I need antibiotics or any other treatment?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

A cough lasting 10 days that is not improving needs proper evaluation rather than trying more medicines on your own. Not all coughs require antibiotics, as many are due to viral infections, allergies, or airway irritation. Consult a doctor who can examine you and decide if tests or specific treatment (like inhalers, anti-allergy medicines, or antibiotics if truly needed) are required. Meanwhile, stay hydrated, take steam inhalation, and avoid dust or smoke.

Have a query?

Directions for Use

  • Cofdex Cough Syrup 100 ml can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Measure the prescribed dose using a measuring cup and administer it orally.
  • Avoid using regular household spoons, as they may not measure the dose correctly.
  • Shake the bottle well before use.

Key Benefits

  • Cofdex Cough Syrup 100 ml contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan used to treat dry cough.
  • Chlorpheniramine maleate helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness.
  • Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose.
  • Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.
  • Thus, Cofdex Cough Syrup 100 ml helps to relieve overall cough, cold and allergic symptoms.

How Cofdex Cough Syrup 100 ml Works

Cofdex Cough Syrup 100 ml is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine (decongestant), and Dextromethorphan (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps shrink blood vessels in the nasal passages, thereby reducing a stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Collectively, it helps relieve a dry cough.

Storage

Store in a cool and dry place away from sunlight
Side effects of Cofdex Cough Syrup 100 ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Try to get 7-9 hours of sleep per night.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is cool, quiet and dark to maximize your sleep quality.
  • Get plenty of sunlight in the morning.
  • Do moderate-intensity exercises most days of the week and avoid strenuous exercise close to bedtime.
  • Limit processed foods and sugary drinks.
  • Avoid caffeine late in the day and drink in moderation in the morning.
  • Take short nap (20 to 30 minutes) mid-afternoon if required.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

What if I have taken an overdose of Cofdex Cough Syrup 100 ml

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include agitation, flushing, confusion, hallucinations, muscle twitching, large pupils, and seizures. In children, excitement may occur first, followed by loss of coordination, drowsiness, loss of consciousness, and seizures. If you/your child experiences these symptoms or suspects that an overdose has occurred, seek immediate medical attention.

Drug Warnings

  • If you are allergic to Cofdex Cough Syrup 100 ml or any other medicines, please tell your doctor.
  • If you are pregnant or breastfeeding, it is advised to inform your doctor before using it.
  • Cofdex Cough Syrup 100 ml is not recommended for use in infants or toddlers without medical advice.
  • If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking this medicine.
  • Avoid taking Cofdex Cough Syrup 100 ml if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days.
  • If you have glaucoma, urinary problems, an enlarged prostate, phenylketonuria (a birth defect that causes accumulation of the amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Cofdex Cough Syrup 100 ml.

Drug-Drug Interactions

verifiedApollotooltip
DextromethorphanRasagiline
Critical
DextromethorphanSelegiline
Critical

Drug-Drug Interactions

Login/Sign Up

DextromethorphanRasagiline
Critical
How does the drug interact with Cofdex Cough Syrup 100 ml:
Taking Rasagiline with Cofdex Cough Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Cofdex Cough Syrup 100 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanSelegiline
Critical
How does the drug interact with Cofdex Cough Syrup 100 ml:
Co-administration of Cofdex Cough Syrup 100 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Cofdex Cough Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanPargyline
Critical
How does the drug interact with Cofdex Cough Syrup 100 ml:
Co-administration of Pargyline and Cofdex Cough Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Cofdex Cough Syrup 100 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanProcarbazine
Critical
How does the drug interact with Cofdex Cough Syrup 100 ml:
Co-administration of Cofdex Cough Syrup 100 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Cofdex Cough Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Cofdex Cough Syrup 100 ml:
Co-administration of Isocarboxazid with Cofdex Cough Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Cofdex Cough Syrup 100 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanTranylcypromine
Critical
How does the drug interact with Cofdex Cough Syrup 100 ml:
Taking Tranylcypromine with Cofdex Cough Syrup 100 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Cofdex Cough Syrup 100 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanPhenelzine
Critical
How does the drug interact with Cofdex Cough Syrup 100 ml:
Co-administration of Phenelzine and Cofdex Cough Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Cofdex Cough Syrup 100 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
PhenylephrineSelegiline
Critical
How does the drug interact with Cofdex Cough Syrup 100 ml:
Co-administration of Selegiline with Cofdex Cough Syrup 100 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Cofdex Cough Syrup 100 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineFurazolidone
Critical
How does the drug interact with Cofdex Cough Syrup 100 ml:
Taking Furazolidone with Cofdex Cough Syrup 100 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Cofdex Cough Syrup 100 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Cofdex Cough Syrup 100 ml only after 14 days of stopping Furazolidone.
PhenylephrineTranylcypromine
Critical
How does the drug interact with Cofdex Cough Syrup 100 ml:
Taking Tranylcypromine with Cofdex Cough Syrup 100 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Cofdex Cough Syrup 100 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as they may increase mucus production. Also, avoid processed or refined foods to relieve a cough.
  • Drink plenty of fluids to avoid a dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Therapeutic Class

[COUGH AND COLD PREPARATIONS ]

All Substitutes & Brand Comparisons

bannner image

Alcohol

Caution

Avoid consumption of alcohol with Cofdex Cough Syrup 100 ml as it may increase drowsiness. Please consult a doctor before consuming alcohol with Cofdex Cough Syrup 100 ml.

bannner image

Pregnancy

Caution

The safety of Cofdex Cough Syrup 100 ml in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

It is unknown whether Cofdex Cough Syrup 100 ml is excreted in human milk. Cofdex Cough Syrup 100 ml is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

bannner image

Driving

Caution

Cofdex Cough Syrup 100 ml may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Cofdex Cough Syrup 100 ml.

bannner image

Liver

Caution

Take Cofdex Cough Syrup 100 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Cofdex Cough Syrup 100 ml with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Caution

The dose and duration must be determined by a paediatrician and administered under strict medical supervision.

bannner image

Heart

Unsafe

Cofdex Cough Syrup 100 ml is contraindicated in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

bannner image

Geriatrics

Unsafe

Cofdex Cough Syrup 100 ml is not safe for use in elderly patients due to its severe side effects.

FAQs

Cofdex Cough Syrup 100 ml is used to treat dry cough.

Cofdex Cough Syrup 100 ml is a combination drug, primarily used to treat dry cough. Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a 'decongestant' that helps in shrinking the blood vessels located in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.

Consuming alcohol, along with Cofdex Cough Syrup 100 ml, may potentiate some of the pharmacologic effects of CNS-active agents. If used together, it may lead to symptoms like confusion, central nervous system depression, impairment of thinking and judgment.

No, you should not take Cofdex Cough Syrup 100 ml if you need to undergo surgery, as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Please inform your doctor before surgery if you are taking Cofdex Cough Syrup 100 ml as the doctor may stop it 72 hours before the surgery.

It is not recommended to take Cofdex Cough Syrup 100 ml along with any antidepressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side effects or any drug interaction. Also, Cofdex Cough Syrup 100 ml should be taken at least 15 days after your last dose of antidepressants.

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take Cofdex Cough Syrup 100 ml and skip the missed dose. Do not take extra medicine to make up for the missed dose.

Cofdex Cough Syrup 100 ml should be used with caution, only when prescribed by a doctor, in patients with glaucoma. As Cofdex Cough Syrup 100 ml may rarely worsen the symptoms of glaucoma.

Yes, Cofdex Cough Syrup 100 ml can cause sleepiness or drowsiness as a common side effect. Cofdex Cough Syrup 100 ml contains dextromethorphan and phenylephrine, which can cause drowsiness, dizziness, nausea, dry mouth, and headache. Therefore, avoid activities that require mental alertness until you know how Cofdex Cough Syrup 100 ml affects you.

No, taking Cofdex Cough Syrup 100 ml at a dose higher than recommended will not make it more effective; it can actually be harmful. Overdosing can lead to severe side effects and toxicity. Therefore, follow your doctor’s instructions carefully.

It is unknown whether Cofdex Cough Syrup 100 ml passes into human milk. Therefore, please consult your doctor if you are supposed to breastfeed while taking Cofdex Cough Syrup 100 ml. Your doctor will prescribe Cofdex Cough Syrup 100 ml only if the benefits outweigh the risks.

Store at a temperature not exceeding 30°C in a cool and dry place. Protect it from sunlight and moisture. Keep out of reach of children.

Cofdex Cough Syrup 100 ml is primarily used to treat dry cough and relieve allergy symptoms such as a runny nose, stuffy nose, sneezing, and watery eyes. However, it is not typically recommended for chronic cough or asthma. Therefore, please consult your doctor for appropriate medications and treatments for chronic cough or asthma.

Both Cofdex Cough Syrup 100 ml and other cold or allergy medicines may contain dextromethorphan, phenylephrine, and chlorpheniramine as active components. Therefore, combining cold or allergy medicines with Cofdex Cough Syrup 100 ml increases the chance of side effects. So, always consult your doctor before combining Cofdex Cough Syrup 100 ml with other medicines.

Avoid alcohol that can increase the drowsiness and dizziness caused by Cofdex Cough Syrup 100 ml. Inform your doctor if you have any pre-existing conditions, such as heart, kidney, lung, liver, thyroid problems, diabetes, glaucoma, or prostate issues. Inform your doctor if you are taking other medications, or if you are breastfeeding, pregnant or planning pregnancy. Drink plenty of fluids while taking Cofdex Cough Syrup 100 ml to loosen mucus. Take Cofdex Cough Syrup 100 ml exactly as prescribed by your doctor. Do not exceed the recommended dose.

It is not known whether Cofdex Cough Syrup 100 ml can cause fetal harm. Therefore, please consult your doctor if you are pregnant before taking Cofdex Cough Syrup 100 ml. Your doctor will prescribe Cofdex Cough Syrup 100 ml only if the benefits outweigh the risks.

The duration for using Cofdex Cough Syrup 100 ml depends on the severity of your symptoms and your doctor's advice. Generally, it is meant for short-term use to relieve symptoms like dry cough, runny nose, and sneezing. Follow your doctor's instructions on how long to use it and consult your doctor if you have any concerns.

The common side effects of Cofdex Cough Syrup 100 ml are dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness or excitation. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - COF0292

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Mar 16, 2026 | 11:59 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Buy best Respiratory System products by

whatsapp Floating Button
Buy Now
Add to Cart