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Cofdrain-P Syrup is used to treat common cold symptoms and allergies (allergic rhinitis). It contains Paracetamol, Phenylephrine hydrochloride, Chlorpheniramine maleate, Sodium citrate, and menthol. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride works by contracting and narrowing the blood vessels. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Sodium citrate works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Menthol relieves minor irritation in the throat and provides a cooling sensation. Together, they help relieve symptoms of a common cold like headache, fever, and allergies like stuffy nose, watery eyes, itching nose/throat, etc.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHLORPHENIRAMINE MALEATE-1MG+MENTHOL-1MG+PARACETAMOL-125MG+PHENYLEPHRINE HYDROCHLORIDE-5MG+SODIUM CITRATE-60MG

Manufacturer/Marketer :

Baxium Healthcare

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Cofdrain-P Syrup

Cofdrain-P Syrup is a prescription medicine to relieve common cold, cough, and allergy symptoms in children. It helps ease nasal congestion, reduces fever, calms coughing, and soothes throat irritation to help your child feel more comfortable. This medication is typically used to manage acute discomfort caused by temporary respiratory infections.

This syrup is usually given two to four times a day, depending on your healthcare provider's recommendations, and it is important to keep doses consistent to keep symptoms under control. It can be given with or without food, though giving it with food or milk may help prevent mild stomach upset. Offering your child warm fluids and ensuring they get plenty of rest will support the medicine's effects and help speed up their recovery.

While this medicine is effective, some children may experience mild side effects like drowsiness, dry mouth, or a slightly upset stomach. These effects are usually temporary, but you should stop giving the medication and consult your doctor immediately if you notice any unusual changes, such as severe skin rashes or extreme restlessness.

Before giving this medicine to your child, talk to your doctor if they have any pre-existing health conditions, especially liver, kidney, or heart issues. Do not give this medicine to children who have a known allergy to any of its individual ingredients or those with severe respiratory difficulties.

This syrup can interact with other medications, such as alternative cold or allergy remedies, which may lead to accidental doubling of doses or unwanted side effects. While this syrup is designed for children, always consult your doctor if considering use in other age groups, and ensure it is never given alongside other medications containing the same active ingredients.

Uses of Cofdrain-P Syrup

Your doctor may prescribe Cofdrain-P Syrup to help manage the following conditions:

  • Fever and mild pain: Paracetamol helps reduce fever and relieve mild aches or discomfort that may occur during a cold or other minor illness.
  • Nasal congestion: Phenylephrine helps reduce swelling inside the nose, which can provide temporary relief from a blocked or stuffy nose.
  • Runny nose, sneezing, and watery eyes: Chlorpheniramine helps relieve symptoms caused by histamine, including a runny nose, sneezing, and watery eyes.
  • Throat and nasal discomfort: Menthol provides a cooling sensation that may temporarily soothe irritation and make the nose and throat feel more comfortable.

Key Benefits

Cofdrain-P Syrup helps relieve several cold and allergy symptoms at the same time, helping your child feel more comfortable while the underlying illness runs its course.

  • Improves overall comfort: Relief from fever, mild aches, a blocked or runny nose, sneezing, and throat irritation can help your child feel more comfortable during a cold or allergy episode.
  • Makes nasal breathing easier: Reducing swelling inside the nose can ease congestion and make it easier for your child to breathe through their nose.
  • Helps soothe throat and cough discomfort: The formulation can help soothe an irritated throat and support the clearance of mucus, which may make coughing more comfortable.
  • May support better rest: By easing bothersome symptoms, Cofdrain-P Syrup may help your child rest more comfortably, particularly when congestion or throat irritation is disturbing sleep.
Side effects of Cofdrain-P Syrup 60 ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Get urgent medical help if you notice abnormal lung sounds with symptoms, like bluish skin, flare-ups of your nostrils, or trouble breathing.
  • If you have asthma or allergies, managing these conditions with inhalers and bronchodilators can help prevent abnormal lung sounds.
  • Infections may need antibiotics or breathing therapy to help open your airways and make breathing easier.
  • Wash your hands regularly and take other steps to avoid getting sick and spreading germs.
  • Doing breathing exercises can help improve your lung function and make breathing easier.
  • Contact your physician right away if you suffer from hypoxia symptoms including chest pain, disorientation, or shortness of breath.
  • Your doctor can monitor your progress and modify treatment programs with the help of routine follow-up sessions.
  • Omega-3 supplements may support the transport of oxygen to tissues.
  • Regular exercise improves cardiovascular health and boosts oxygen delivery to tissues.
  • Quit smoking, as it can worsen hypoxia.

Directions for Use

  • Cofdrain-P Syrup can be administered with or without food as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Administer the prescribed dose to the child using the measuring cup/dosing syringe.
  • Shake well before use.

How Cofdrain-P Syrup Works

Cofdrain-P Syrup contains paracetamol, phenylephrine hydrochloride, chlorpheniramine maleate, sodium citrate, and menthol. Each ingredient has a different role in providing symptom relief. Paracetamol acts mainly in the central nervous system to reduce pain and fever. It helps lower an elevated body temperature and relieve mild aches and discomfort. Phenylephrine hydrochloride narrows small blood vessels in the lining of the nose. This reduces swelling in the nasal passages and can temporarily relieve nasal congestion. Chlorpheniramine maleate blocks the action of histamine, a substance released during allergic reactions. This helps reduce symptoms such as sneezing, a runny nose, and watery eyes. Sodium citrate acts mainly as an alkalinising and buffering agent. It helps regulate acidity in the formulation and should not be described as directly breaking down or thinning mucus. Menthol produces a cooling sensation in the nose and throat, which may temporarily soothe irritation and make breathing feel more comfortable. Together, these ingredients provide temporary relief from several symptoms associated with colds and allergies. They do not treat the underlying viral infection that causes most common colds.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Consult your doctor

If your child has a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

Take Cofdrain-P Syrup with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

For children below 2 years of age, please consult a doctor before giving Cofdrain-P Syrup.

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Heart

Consult your doctor

Please consult your doctor before giving Cofdrain-P Syrup to your child. Your doctor will prescribe Cofdrain-P Syrup if the benefits outweigh the risks.

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Geriatrics

Not applicable

Cofdrain-P Syrup is for paediatric patients only.

What if I have taken an overdose of Cofdrain-P Syrup

If you suspect your child has taken more than the prescribed amount, seek immediate medical attention. Even if your child does not show any immediate signs of discomfort, prompt medical evaluation is critical to prevent liver damage or other serious complications.

Diet & Lifestyle Advise

  • Offer enough fluids: Encourage your child to drink water, warm fluids, or other age-appropriate drinks regularly. Warm liquids may help soothe an irritated throat and make mucus easier to clear.
  • Use saline for a blocked nose: Saline nasal drops or spray can help loosen dried mucus and keep the nasal passages moist. Use a product suitable for your child's age.
  • Keep the air comfortable: A cool-mist humidifier may help if indoor air is dry. Clean the humidifier regularly according to the manufacturer's instructions to prevent the growth of mould and bacteria.
  • Encourage rest: Allow your child enough sleep and quiet time while they are unwell, with a gradual return to normal activities as they feel better.
  • Avoid smoke and other irritants: Keep your child away from cigarette smoke, dust, strong fragrances, and other irritants that may worsen coughing or nasal and throat irritation.
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How Soon It Starts Working

The time required for Cofdrain-P Syrup to start to work: The onset time of Cofdrain-P Syrup has not been clinically established. The time for which the effects of Cofdrain-P Syrup last: The duration of Cofdrain-P Syrup’s effect is clinically not established.

What if you forget to take Cofdrain-P Syrup

If you miss a dose, give it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and return to your regular schedule. Do not give a double dose to make up for a missed one.

Storage

• Store Cofdrain-P Syrup at room temperature, ideally between 15°C and 30°C.

Drug Warnings

  • Check other medicines before giving them: Cofdrain-P Syrup already contains paracetamol, phenylephrine, and chlorpheniramine. Do not give another medicine containing the same ingredients unless your child's doctor or pharmacist advises it, as this could result in an excessive dose.
  • Measure each dose carefully: Use the oral syringe, measuring cup, or other dosing device supplied or recommended with the medicine. Do not use a household spoon, as it may not measure the dose accurately.
  • Watch for drowsiness: Chlorpheniramine can make some children sleepy or less alert. If your child is affected, avoid activities such as cycling or other activities that require good coordination and attention.
  • Give only the recommended dose: Follow the dose and dosing interval prescribed or recommended for your child. Do not give extra doses if symptoms continue, as too much paracetamol can cause serious liver damage.
  • Know when to seek medical advice: Consult your doctor if your child's symptoms worsen, do not improve as expected, or are accompanied by difficulty breathing, unusual drowsiness, dehydration, or a persistent high fever.

Drug-Drug Interactions

verifiedApollotooltip
  • Other Paracetamol-containing medicines: Giving these together significantly increases the risk of serious liver damage.
  • Monoamine Oxidase Inhibitors (MAOIs): Combining this syrup with MAOIs (or within 14 days of stopping them) can cause a dangerous spike in blood pressure.
  • Sedatives or other antihistamines: Can cause extreme drowsiness and slow down breathing in children.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Cofdrain-P Syrup when used as directed.     
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIALLERGIC]

FAQs

Cofdrain-P Syrup is used to treat Common cold and Allergies.
Cofdrain-P Syrup contains Paracetamol, Phenylephrine hydrochloride, Chlorpheniramine maleate, Sodium citrate, and menthol. Paracetamol blocks messengers that cause pain. Phenylephrine hydrochloride works by contracting and narrowing the nasal blood vessels. Chlorpheniramine maleate blocks the action of histamine (a substance responsible for causing allergic reactions). Sodium citrate works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Menthol relieves minor irritation in the throat due to allergy and provides a cooling sensation. Together Cofdrain-P Syrup prevents symptoms of the common cold and allergic rhinitis.
Cofdrain-P Syrup may be used to relieve pain and fever associated with cold. Paracetamol, in Cofdrain-P Syrup is an analgesic (relieves pain) and antipyretic (reduces fever) that inhibits the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
You are not recommended to give more than the prescribed dose of Cofdrain-P Syrup as it may cause liver damage and lead to severe adverse effects. Therefore, give Cofdrain-P Syrup to your child only in doses as advised by a doctor.
Your child’s condition may improve after a few days of taking Cofdrain-P Syrup. Complete the duration of treatment to treat the child’s condition effectively.
No, Cofdrain-P Syrup is not recommended for children below 2 years of age. However, consult the doctor if you have any concerns.
Cofdrain-P Syrup should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
Cofdrain-P Syrup can be taken with other medicines if advised by the doctor. Let the doctor know if the child is taking medications such as anti-allergic drugs (diphenhydramine, cetirizine), muscle relaxants (cyclobenzaprine), antidepressants (duloxetine, escitalopram), anticonvulsants (clonazepam), antianxiety drug (alprazolam), sleeping agent (ramelteon), cough suppressants (dextromethorphan), bronchodilator (albuterol), pain and fever medicines (paracetamol), pain killers (ibuprofen) as these medications may cause interactions.
No, you should not give the medicine which is prescribed for you to your child. Medications prescribed for adults often contain higher doses or ingredients that may not be safe for children and may cause harm. Always give the medication prescribed by the doctor to prevent side effects.
No, you should not use Cofdrain-P Syrup to make your child sleep as it is used to treat symptoms of the common cold and allergies (allergic rhinitis). Consult the doctor if you have any concerns.
The side effects of Cofdrain-P Syrup include nausea, vomiting, drowsiness, nervousness, mild headache, dizziness, constipation, insomnia (difficulty in falling or staying asleep), blurred vision, and dry mouth. Consult the doctor if any of these symptoms persist or worsen.
This medicine is intended to relieve certain cold and allergy symptoms, such as fever, nasal congestion, runny nose, sneezing, and throat irritation. It is not a specific treatment for a dry cough. If your child has a persistent dry cough, breathing difficulty, wheezing, or a cough that is getting worse, consult your doctor for appropriate evaluation and treatment.
Yes, this syrup contains an antihistamine that commonly causes mild drowsiness or sleepiness. It is often best given close to naptime or bedtime. Talk to your doctor if the sleepiness seems excessive.
If your child vomits shortly after taking the medicine, do not immediately give another dose, as you cannot be sure how much was absorbed. Talk to your doctor or pharmacist for specific advice on when to give the next dose safely.
Yes, you can give this syrup with or without food. However, if your child has a sensitive stomach, giving it with a small meal or a glass of milk can help prevent mild nausea or upset.
You should generally not give this medicine for more than 3 to 5 consecutive days without consulting a paediatrician. If symptoms persist or worsen, talk to your doctor for a proper evaluation.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

F-10, Divya Building, Jubli Complex, Powai, Mumbai-400001
Other Info - COF0228
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