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  3. Col 2 MIU Injection 1's

Col 2 MIU Injection 1's, Pack of 1
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Col 2 MIU Injection 1's is used to treat bacterial infections. It contains Colistimethate which works by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as stomach upset, itching, rash, and fever. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

COLISTIMETHATE-2000000IU

Manufacturer/Marketer :

Gufic Bioscience Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Col 2 MIU Injection 1's

Col 2 MIU Injection 1's belongs to a class of drugs called antibiotics used in the treatment of severe bacterial infections. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Col 2 MIU Injection 1's does not work against infections caused by a virus.

Col 2 MIU Injection 1's contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damaging bacterial cell membranes and kills bacteria.

Take Col 2 MIU Injection 1's as prescribed by your doctor. You are advised to take Col 2 MIU Injection 1's for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, stomach upset, tingling, or difficulty in breathing. Most of these side effects of Col 2 MIU Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Col 2 MIU Injection 1's or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking Col 2 MIU Injection 1's. If you are pregnant or breastfeeding, please inform your doctor before taking Col 2 MIU Injection 1's. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as Col 2 MIU Injection 1's may cause confusion, vision problems, or dizziness.  If you are on dialysis, inform your doctor before taking Col 2 MIU Injection 1's so that the dose may be reduced accordingly.

Uses of Col 2 MIU Injection 1's

Treatment of Several bacterial infections

Directions for Use

• Your doctor will determine the dosage and timing of Col 2 MIU Injection 1's based on the severity of your infection. Typically, it is administered every 6-12 hours.• Col 2 MIU Injection 1's is administered by a healthcare professional as an infusion over 30–60 minutes or as a rapid injection within 5 minutes into a vein. • Do not self-administer it.

Medicinal Benefits

Col 2 MIU Injection 1's contains Colistimethate, a narrow-spectrum antibiotic that is active against gram-negative bacteria. Col 2 MIU Injection 1's binds to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria. Col 2 MIU Injection 1's is used when other antibiotics are not suitable.

How Col 2 MIU Injection 1's Works

Col 2 MIU Injection 1's contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damaging bacterial cell membranes and kills bacteria.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Col 2 MIU Injection 1's

Use Col 2 MIU Injection 1's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness, confusion, loss of balance/coordination, rapid eye movement, severe numbness/tingling, weak/shallow breathing, problems with speech, and loss of consciousness. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Col 2 MIU Injection 1's or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking Col 2 MIU Injection 1's. If you are pregnant or breastfeeding, please inform your doctor before taking Col 2 MIU Injection 1's. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as Col 2 MIU Injection 1's may cause confusion, vision problems, or dizziness. If you are on dialysis, inform your doctor before taking Col 2 MIU Injection 1's so that the dose may be reduced accordingly. Inform your anesthetist that you are taking Col 2 MIU Injection 1's as it may increase the effects of muscle relaxants used in general anesthesia. You are recommended to complete the full course of Col 2 MIU Injection 1's as prescribed by your doctor for effective results.

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
ColistinTobramycin
Severe

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
How does the drug interact with Col 2 MIU Injection:
Coadministration of Col 2 MIU Injection along with BCG vaccine can reduce the treatment outcomes.

How to manage the interaction:
Taking Col 2 MIU Injection with BCG vaccine is avoided as it may lead to an interaction, please consult your doctor before taking it.
ColistinTobramycin
Severe
How does the drug interact with Col 2 MIU Injection:
Coadministration of Tobramycin with Col 2 MIU Injection can increase the blood levels and risk of Col 2 MIU Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Col 2 MIU Injection and Tobramycin, you can take these medicines together if prescribed by your doctor. However, if you experience, shortness of breath, muscle pain, dizziness, or palpitations, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
ColistinAdefovir dipivoxil
Severe
How does the drug interact with Col 2 MIU Injection:
Combining Col 2 MIU Injection with Adefovir dipivoxil may decrease Col 2 MIU Injection's excretion rate, which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Col 2 MIU Injection and Adefovir dipivoxil, you can take these medicines together if prescribed by your doctor. However, if you experience any irregular urination, swelling, shortness of breath, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinPancuronium
Severe
How does the drug interact with Col 2 MIU Injection:
Using Pancuronium with Col 2 MIU Injection can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Col 2 MIU Injection and Pancuronium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinEverolimus
Severe
How does the drug interact with Col 2 MIU Injection:
Coadministration of Col 2 MIU Injection with Everolimus can increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction between Col 2 MIU Injection and Everolimus, it can be taken if prescribed by a doctor. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, or weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
ColistinStreptomycin
Severe
How does the drug interact with Col 2 MIU Injection:
Coadministration of Streptomycin with Col 2 MIU Injection may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Col 2 MIU Injection and Streptomycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, muscle pain, dizziness, or palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ColistinAmikacin
Severe
How does the drug interact with Col 2 MIU Injection:
Coadministration of Col 2 MIU Injection with Amikacin can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Col 2 MIU Injection and Amikacin, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ColistinIohexol
Severe
How does the drug interact with Col 2 MIU Injection:
Combining Col 2 MIU Injection with Iohexol can increase the effect or side effects of Iohexol.

How to manage the interaction:
Although there is a possible interaction between Col 2 MIU Injection and Iohexol, you can take these medicines if prescribed by your doctor. However, if you experience vomiting, loss of appetite, irregular urination, swelling, shortness of breath, muscle cramps, or weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinHuman immunoglobulin
Severe
How does the drug interact with Col 2 MIU Injection:
Taking Human immunoglobulin with Col 2 MIU Injection, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Col 2 MIU Injection, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
ColistinCisatracurium
Severe
How does the drug interact with Col 2 MIU Injection:
Coadministration of Cisatracurium with Col 2 MIU Injection may increase the risk of side effects of Cisatracurium.

How to manage the interaction:
Although there is a possible interaction of Cisatracurium with Col 2 MIU Injection, it can be taken if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, Slurred speech, Vertigo, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Col 2 MIU Injection 1's to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Col 2 MIU Injection 1's.
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Col 2 MIU Injection 1's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Interaction of Col 2 MIU Injection 1's with alcohol is unknown. Please consult a doctor before consuming alcohol while using Col 2 MIU Injection 1's.

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Pregnancy

Caution

Col 2 MIU Injection 1's is a category C pregnancy drug and is given to pregnant women only if it is essential. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Col 2 MIU Injection 1's may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Col 2 MIU Injection 1's may cause confusion, vision problems or dizziness. Therefore, avoid driving if you experience any of these symptoms after taking Col 2 MIU Injection 1's.

bannner image

Liver

Caution

Take Col 2 MIU Injection 1's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Col 2 MIU Injection 1's with caution, especially if you have a history of Kidney diseases/conditions as Col 2 MIU Injection 1's may affect kidney function. The dose may be adjusted by your doctor as required.

bannner image

Children

Caution

Col 2 MIU Injection 1's should be used with caution in children and in doses as prescribed by a doctor. Special care should be taken in new-born and premature babies as kidneys are not developed fully.

Have a query?

FAQs

Col 2 MIU Injection 1's is used to treat bacterial infections.

Col 2 MIU Injection 1's contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria.

You are not recommended to take Col 2 MIU Injection 1's with gentamicin as co-administration of these two medicines may increase the risk of severe adverse effects such as kidney problems, hearing loss or respiratory depression especially in elderly people and in those who have preexisting kidney disease or who are dehydrated. However, please consult your doctor before taking Col 2 MIU Injection 1's with other medicines.

Col 2 MIU Injection 1's may cause dizziness as a common side effect. Avoid driving if you feel dizzy after taking Col 2 MIU Injection 1's. However, if the condition persists or worsens, please consult a doctor.

Col 2 MIU Injection 1's should be used with caution in patients receiving dialysis (the process of filtration and purification of blood using a machine). Therefore, if you are receiving dialysis, please inform your doctor before taking Col 2 MIU Injection 1's so that the dose may be adjusted accordingly.

You are recommended to take Col 2 MIU Injection 1's with extreme caution if you have kidney disease as it may worsen the condition. Regular monitoring of kidney functioning is recommended while taking Col 2 MIU Injection 1's. Therefore, inform your doctor if you have any kidney problems before taking Col 2 MIU Injection 1's.

Before taking Col 2 MIU Injection 1's, inform your doctor if you have a history of kidney problems, myasthenia gravis (a condition that causes muscle weakness), porphyria (a blood disorder), or asthma. These conditions may affect your treatment or require special monitoring.

Col 2 MIU Injection 1's is given by a healthcare professional as an infusion over 30–60 minutes or as a rapid injection within 5 minutes into a vein. Do not self-administer.

Do not use Col 2 MIU Injection 1's if you are allergic to its active substances or any other polymyxins (group of antibiotics to treat bacterial infection). If you are unsure, consult your doctor before receiving Col 2 MIU Injection 1's.

Col 2 MIU Injection 1's is prescribed during pregnancy only if your doctor thinks that the benefits are greater than the potential risks. The safety of Col 2 MIU Injection 1's during pregnancy has not been fully established. Therefore, consult your doctor before taking Col 2 MIU Injection 1's if you are pregnant.

Col 2 MIU Injection 1's is safe when used as per the dose and duration advised by a doctor.

Col 2 MIU Injection 1's causes side effects such as dizziness, stomach upset, tingling, and difficulty in breathing. However, these do not require any medical treatment and gradually reduce over time. Contact a doctor if these side effects persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

37,1St Floor, Kamala Bhavan Ii, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (India).
Other Info - COL1534

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:47 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.5648.pdf
  2. https://www.drugs.com/cdi/colistimethate.html
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