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compositionComposition:CABERGOLINE-0.25MG
prescription
Prescription Medicine
info
Colette 0.25mg Tablet

Colette 0.25mg Tablet is used to treat hyperprolactinemia (high levels of prolactin). It contains cabergoline, which decreases the amount of prolactin in the body. In some cases, you may experience side effects such as blurred vision, drowsiness, constipation, vomiting, dizziness, headache, and fatigue. Before starting Colette 0.25mg Tablet, inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CABERGOLINE-0.25MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Colette 0.25mg Tablet

Colette 0.25mg Tablet is prescribed to treat health conditions caused by high levels of a hormone called prolactin. It is primarily used to treat pituitary gland disorders, such as non-cancerous tumors that release excess prolactin, or to help stop breast milk production when medically necessary. This medicine helps restore hormonal balance in your body.

You will typically take Colette 0.25mg Tablet once or twice a week, on the exact days your doctor recommends. It is important to take this medicine consistently at the same times each week to maintain steady hormone levels. You can take this oral tablet with or without food, though taking it with a meal can help prevent an upset stomach. Eating a balanced diet and managing stress can also support your hormone health while using this treatment.

Many people taking Colette 0.25mg Tablet experience mild side effects like nausea, dizziness, or mild headaches as their body adjusts. However, you must contact your doctor immediately if you notice serious symptoms such as shortness of breath, a persistent cough, or swelling in your hands or feet.

Talk to your doctor before starting Colette 0.25mg Tablet if you have a history of liver damage, high blood pressure, or heart valve disorders. Do not take this if you have uncontrolled high blood pressure or a history of severe heart valve scarring.

Certain medicines, such as blood pressure drugs or psychiatric medications, can interact with Colette 0.25mg Tablet and cause severe dizziness or reduced effectiveness. Avoid drinking alcohol while taking this medicine, as it can worsen drowsiness and dizzy spells. If you are pregnant, breastfeeding, or planning a family, talk to your doctor, as this medicine directly affects breast milk production and hormonal cycles.

Uses of Colette 0.25mg Tablet

Colette 0.25mg Tablet is prescribed to treat conditions associated with excessive prolactin production and related hormonal imbalances, including:

  • Hyperprolactinaemia (High prolactin levels): Colette 0.25mg Tablet helps lower abnormally high levels of prolactin, a hormone that can cause irregular periods, fertility issues, and unwanted breast milk production.
  • Pituitary gland tumours (Prolactinomas): It helps shrink non-cancerous tumours of the pituitary gland that produce excess prolactin, relieving associated symptoms and helping restore normal hormone function.
  • Suppression of breast milk production: When medically necessary, it can be used to prevent or stop breast milk production after childbirth, miscarriage, or abortion.
     

Key Benefits

Colette 0.25mg Tablet offers the following benefits when used as prescribed:

  • Reduces elevated prolactin levels: It effectively lowers prolactin levels, helping correct hormone imbalances and their associated symptoms.
  • Restores menstrual regularity: In women, normalising prolactin levels can help restore regular menstrual cycles and improve reproductive health.
  • Improves fertility: By correcting prolactin-related hormonal disturbances, it may improve the chances of conception in individuals experiencing fertility problems.
  • Supports sexual health: In men, reducing elevated prolactin levels may help improve libido, sexual function, and overall well-being.
  • Helps shrink prolactin-secreting tumours: It can reduce the size of prolactinomas, helping relieve symptoms caused by tumour pressure, such as headaches and vision disturbances.
  • Convenient dosing schedule: Due to its long duration of action, Colette 0.25mg Tablet is often taken only once or twice weekly, making treatment easier to maintain.
     

Directions for Use

To get the best results from Colette 0.25mg Tablet, follow these instructions carefully: 

  • Swallow the Colette 0.25mg Tablet tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • You can take this medicine with or without food, but taking it with your evening meal may help reduce common side effects like nausea or dizziness.
  • Take the medicine on the exact days of the week prescribed by your doctor. It can help to mark these days on a calendar or set a weekly reminder.
  • Always follow your doctor's exact instructions, and never change your dose or stop taking this medicine without consulting them first.
     

How Colette 0.25mg Tablet Works

Colette 0.25mg Tablet works by acting directly on the dopamine receptors in your brain. Dopamine is a natural chemical messenger that, among other functions, controls the release of prolactin from the pituitary gland. When you take Colette 0.25mg Tablet, it mimics the action of dopamine. This signals the pituitary gland to slow down and reduce the amount of prolactin it releases into your bloodstream. By lowering these hormone levels to a normal range, it helps reverse the symptoms of hyperprolactinaemia and can even shrink prolactin-producing tumours.
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Alcohol

Caution

Colette 0.25mg Tablet is known to cause dizziness. So, intake of alcohol along with Colette 0.25mg Tablet should not be done.

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Pregnancy

Caution

If you are pregnant, think you might be pregnant or intend to have a kid, ask your doctor for advice before taking Colette 0.25mg Tablet. You should also be careful not to get pregnant for at least one month after you stop taking this drug. If you become pregnant while taking Colette 0.25mg Tablet, stop taking Colette 0.25mg Tablet and inform your doctor, who will monitor your pregnancy, as Colette 0.25mg Tablet can result in congenital abnormalities if you use it during pregnancy.

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Breast Feeding

Caution

Colette 0.25mg Tablet will stop you from producing milk for your baby, and you should not take this medicine if you plan to breastfeed.

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Driving

Caution

Colette 0.25mg Tablet is known to cause dizziness. So, driving or any machinery which requires concentration should be avoided.

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Liver

Caution

Colette 0.25mg Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Colette 0.25mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Colette 0.25mg Tablet should not be used by females below the age of 16 years. It can be fatal.

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Heart

Caution

Exercise caution while taking Colette 0.25mg Tablet, if you have any heart problems as it can increase the risk of heart disease. Please consult your physician.

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Geriatrics

Caution

Exercise caution while giving Colette 0.25mg Tablet in elderly patients. Please consult your physician.

What if I have taken an overdose of Colette 0.25mg Tablet

Do not take more than the prescribed dose of Colette 0.25mg Tablet as it may cause overdose. The symptoms of overdose include fainting, a stuffy nose and hallucinations. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stand Up Slowly: To manage sudden drops in blood pressure (which can cause dizziness), stand up slowly from sitting or lying positions.
  • Stay Well-Hydrated: Stay well-hydrated by drinking plenty of water throughout the day, which can help minimise headaches and lightheadedness.
  • Limit Caffeine and Avoid Alcohol: Limit your intake of caffeine and avoid alcohol, as these can worsen sleep disturbances and increase dizziness.
  • Eat Small, Frequent Meals: Eat small, frequent meals if you experience nausea after taking your dose.
  • Exercise Gently and Regularly: Get regular gentle exercise to support overall cardiovascular health, but avoid extreme physical exertion if you suffer from dizzy spells.
     

Have a query?

How Soon It Starts Working

The time required for Colette 0.25mg Tablet to start to work: Colette 0.25mg Tablet ideally shows its action within 2 to 3 hours after administration.

The time for which the effects of Colette 0.25mg Tablet last: The duration of action for Colette 0.25mg Tablet is unknown.

What if you forget to take Colette 0.25mg Tablet

If you miss a dose of Colette 0.25mg Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

•Store Colette 0.25mg Tablet tablets at room temperature, preferably between 20°C and 25°C, or as directed on the product packaging. •Keep the tablets in their original container or blister pack to protect them from moisture and light.

Drug Warnings

  • Monitor Your Blood Pressure: Check your blood pressure regularly, as this medicine can cause your blood pressure to drop suddenly, especially when you first start taking it.
  • Use Caution with Driving and Machinery: Avoid driving, operating machinery, or performing dangerous tasks until you know how this medicine affects you, as it can cause sudden sleepiness or dizziness.
  • Attend Regular Follow-Up Appointments: Keep all follow-up appointments with your doctor so they can monitor your hormone levels and check your heart and lung function.
  • Watch for Behavioural or Mood Changes: Be aware of mood changes; some patients report experiencing intense, uncontrollable impulses like gambling, binge eating, or hypersexuality. Tell your doctor immediately if you notice these behavioural changes.
     

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Drug-Drug Interactions
The following medications may affect how Colette 0.25mg Tablet works or increase the risk of side effects:

  • Blood pressure medications: Taking Colette 0.25mg Tablet with antihypertensive medicines may cause your blood pressure to fall too low, increasing the risk of dizziness, light-headedness, or fainting.
  • Dopamine antagonists: Medicines such as metoclopramide, domperidone, phenothiazines, butyrophenones, or certain antipsychotics can reduce the effectiveness of Colette 0.25mg Tablet because they oppose its action on dopamine receptors.
  • Macrolide antibiotics: Antibiotics such as erythromycin and clarithromycin may increase Colette 0.25mg Tablet levels in the body, potentially raising the risk of side effects.
  • Other ergot-derived medicines: Concurrent use with other ergot alkaloids may increase the risk of ergot-related adverse effects and should only be undertaken under medical supervision.

Drug-Food Interactions

Certain foods and beverages may affect the tolerability of Colette 0.25mg Tablet, including:

  • Alcohol: Avoid or limit alcohol consumption while taking Colette 0.25mg Tablet, as it can increase drowsiness, dizziness, light-headedness, and the risk of fainting.

Drug-Disease Interactions

Some medical conditions may affect the safety or suitability of Colette 0.25mg Tablet, including:

  • Heart valve disease: Colette 0.25mg Tablet should not be used in patients with a history of heart valve disorders, valvular fibrosis, or evidence of valve abnormalities unless specifically advised by a specialist.
  • Liver impairment: Patients with severe liver disease may require closer monitoring or dose adjustments because Colette 0.25mg Tablet may be cleared from the body more slowly.
  • Uncontrolled hypertension: This medicine should be used with caution and may not be suitable for individuals with severe or uncontrolled high blood pressure.
  • Fibrotic disorders: Patients with a history of pulmonary, pericardial, or retroperitoneal fibrosis require careful evaluation before starting Colette 0.25mg Tablet, as ergot-derived medicines have been associated with fibrotic complications.
  • Psychiatric disorders: Colette 0.25mg Tablet should be used cautiously in patients with a history of severe psychiatric illness, as dopamine agonists may occasionally worsen certain psychiatric symptoms.
     

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Colette 0.25mg Tablet used to treat hyperprolactinemia (high levels of prolactin, a natural substance that allows breast development and milk production in women).
Colette 0.25mg Tablet works by mimicking the action of dopamine. Thereby decreases the amount of prolactin in the body.
If you miss a dose of Colette 0.25mg Tablet, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, do not take a double dose to make up for a missed one.
Colette 0.25mg Tablet can be taken with or without food. However, taking it with a meal, snack, or shortly after food may help reduce side effects such as nausea, vomiting, and stomach discomfort. Follow your doctor's instructions regarding how to take your medicine.
Colette 0.25mg Tablet contains cabergoline, a medication that treats high levels of prolactin in your blood.
Colette 0.25mg Tablet is an oral medication taken by mouth with or without food as directed by your doctor. The dosage is based on your medical condition and response to the treatment.
Common side effects of Colette 0.25mg Tablet may include blurred vision, drowsiness, constipation, vomiting, dizziness, headache, and fatigue. Most of these side effects are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
You may begin to see a decrease in prolactin levels within a few weeks of starting treatment, but it can take several months to experience the full benefits. Your doctor will monitor your blood levels regularly to track progress. Talk to your doctor if you have concerns about your timeline.
Colette 0.25mg Tablet is often used to restore fertility by normalising hormone levels, but you should stop taking it once pregnancy is confirmed. Always discuss your pregnancy plans with your doctor before starting or stopping this medication.
This medicine has a very long-lasting effect in the body, which allows it to control prolactin levels effectively even when taken only once or twice a week. Do not take it more frequently than prescribed. Talk to your doctor or pharmacist if you have questions about your schedule.
Yes, in some cases, it can cause severe drowsiness or even cause you to fall asleep suddenly during daytime activities. Avoid driving or operating machinery until you know how the medicine affects you. Talk to your doctor if you experience extreme sleepiness.
You should contact your doctor immediately if you notice unusual mood swings, increased anxiety, or intense urges like compulsive gambling or spending. These are recognised side effects that require medical evaluation.
Your doctor will schedule regular blood tests to check your prolactin levels. They may also perform heart scans (echocardiograms) or lung function tests periodically to ensure the medicine is safe for you long-term. Talk to your doctor to learn more.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can worsen side effects such as severe dizziness, drowsiness, and lightheadedness, increasing your risk of falls or fainting. Talk to your doctor if you have questions about alcohol use.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - CO26024
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