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COMBANTRIN A 400MG TABLET

COMBANTRIN A 400MG TABLET

Prescription drug
 Trailing icon
Consult Doctor

Manufacturer/Marketer

Pfizer Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About COMBANTRIN A 400MG TABLET

COMBANTRIN A 400MG TABLET belongs to a group of antiparasitic drugs called 'anthelmintic' used to treat parasites worm infections like neurocysticercosis (infection caused by pork tapeworm) and cystic hydatid disease (infection caused by dog tapeworm). Additionally, COMBANTRIN A 400MG TABLET is also used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites. 

COMBANTRIN A 400MG TABLET contains ‘Albendazole’, which works by inhibiting tubulin polymerisation. This causes metabolic disruption and energy depletion in the parasite, which leads to its immobilisation. Thereby, COMBANTRIN A 400MG TABLET kills the susceptible helminth and treats the infection. 

Take COMBANTRIN A 400MG TABLET as prescribed. You are advised to take COMBANTRIN A 400MG TABLET for as long as your doctor has prescribed it for you, depending on your medical condition. You may experience certain common side effects, such as stomach pain, nausea, vomiting, headache, and dizziness in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

COMBANTRIN A 400MG TABLET might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu or colds. Consult your doctor if you notice unusual bleeding or bruising, as you may bleed or bruise easily while taking COMBANTRIN A 400MG TABLET. Do not take COMBANTRIN A 400MG TABLET if you are pregnant or planning for pregnancy as it may cause foetal harm. Do not breastfeed during and for a minimum of 5 days after treatment with COMBANTRIN A 400MG TABLET. COMBANTRIN A 400MG TABLET may cause dizziness, so be cautious while driving. COMBANTRIN A 400MG TABLET can be given to children if prescribed by the doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of COMBANTRIN A 400MG TABLET

Treatment of Parasitic worm infections

Medicinal Benefits

COMBANTRIN A 400MG TABLET belongs to a group of medicines called anthelmintic used to treat worm infections such as neurocysticercosis (infection caused by pork tapeworm) and cystic hydatid disease (infection caused by dog tapeworm). COMBANTRIN A 400MG TABLET is also used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites. COMBANTRIN A 400MG TABLET is a broad-spectrum anthelmintic drug which is highly effective against a wide range of intestinal helminths, including cestodes, nematodes, and trematodes. It is also effective against tissue helminth infections like cutaneous larva migrans (parasitic skin infections). COMBANTRIN A 400MG TABLET exhibits ovicidal, larvicidal and vermicidal activity. COMBANTRIN A 400MG TABLET inhibits tubulin polymerisation, which causes metabolic disruption and energy depletion in the parasite. This leads to the immobilisation of the parasite. Thereby, COMBANTRIN A 400MG TABLET kills the susceptible helminth and treats the infection.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use.Chewable tablet: Chew the tablet completely and swallow. Do not swallow it as a whole.

Storage

Store in a cool and dry place away from sunlight

Side Effects of COMBANTRIN A 400MG TABLET

  • Stomach pain
  • Nausea
  • Vomiting
  • Headache
  • Dizziness

Drug Warnings

Do not take COMBANTRIN A 400MG TABLET if you are allergic to any of its contents. COMBANTRIN A 400MG TABLET may cause bone marrow suppression, aplastic anaemia, and agranulocytosis. Inform your doctor if you have/had liver disease; if you have any surgery, including dental surgery. Consult your doctor immediately if you experience seizures, vomiting, headache, extreme tiredness, or behaviour changes while taking COMBANTRIN A 400MG TABLET. Regular blood cell count and liver function monitoring is advised during treatment with COMBANTRIN A 400MG TABLET. COMBANTRIN A 400MG TABLET might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu or cold. Consult your doctor if you notice unusual bleeding or bruising, as you may bleed or bruise easily while taking COMBANTRIN A 400MG TABLET. Do not take COMBANTRIN A 400MG TABLET if you are pregnant or planning for pregnancy as it may cause foetal harm. Do not breastfeed during and for minimum of 5 days after treatment with COMBANTRIN A 400MG TABLET. COMBANTRIN A 400MG TABLET may cause dizziness, so be cautious while driving. COMBANTRIN A 400MG TABLET can be given to children if prescribed by the doctor.

Drug Interactions

Drug-Drug Interactions: COMBANTRIN A 400MG TABLET may have interaction with anthelmintic (praziquantel), corticosteroid (dexamethasone), antacid (cimetidine), anti-asthma (theophylline).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions:  Inform your doctor if you have myelosuppression (bone marrow suppression), hepatobiliary dysfunction (liver and biliary disease), neurological disorder, and kidney dysfunction.

Drug-Drug Interactions Checker List

  • DEXAMETHASONE
  • CIMETIDINE
  • THEOPHYLLINE
  • PRAZIQUANTEL

Habit Forming

No

Diet & Lifestyle Advise

  • Regularly wash your hands with soap and water, especially after using the toilet and while eating.
  • Avoid eating raw fish and meat.
  • Thoroughly cook meat before eating.
  • Wash all fruits and vegetables properly before consuming.
  • Wash or reheat food that has been around for a long time.
  • Avoid contact with soil that may be contaminated with faeces.
  • Avoid foods that have been kept open in the markets as they can be contaminated.
  • Drink boiled and purified water.

Special Advise

  • Regular monitoring of blood cell count and liver function is advised during treatment with COMBANTRIN A 400MG TABLET.

  • COMBANTRIN A 400MG TABLET might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu or cold.

  • Consult your doctor if you notice unusual bleeding or bruising as you may bleed or bruise easily while taking COMBANTRIN A 400MG TABLET.

  • COMBANTRIN A 400MG TABLET will not treat a viral infection such as the flu or a common cold.

Disease/Condition Glossary

Parasitic worm infections: Parasitic worms are also called intestinal worms or helminths. They live in and feed on the hosts leading to weakness and diseases. Common types of intestinal worms are roundworms and flatworms, such as tapeworms and flukes. Worm infections could occur due to consumption of contaminated water, food or soil, contact with contaminated faeces, poor sanitisation and poor hygiene. Symptoms of worm infections include abdominal pain, diarrhoea, nausea, vomiting, gas, bloating, fatigue, unexplained weight loss, and dysentery (bloody stools).

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Alcohol

Caution

It is unknown whether alcohol interacts with COMBANTRIN A 400MG TABLET. Please consult your doctor.

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Pregnancy

Unsafe

COMBANTRIN A 400MG TABLET belongs to pregnancy category C. Do not take COMBANTRIN A 400MG TABLET if you are pregnant or planning for pregnancy as it may cause foetal harm. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Unsafe

Do not breastfeed during and for minimum 5 days after treatment with COMBANTRIN A 400MG TABLET. Please consult your doctor if you have any concerns regarding this.

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Driving

Caution

COMBANTRIN A 400MG TABLET may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

COMBANTRIN A 400MG TABLET can be given to children if prescribed by the doctor. Please consult your doctor. Your doctor will prescribe the dose of this medicine based on the age and body weight of your child.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - COM0069

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

COMBANTRIN A 400MG TABLET is used to treat parasite worm infections like neurocysticercosis (infection caused by pork tapeworm) and cystic hydatid disease (infection caused by dog tapeworm). Additionally, it is also used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites.
COMBANTRIN A 400MG TABLET causes metabolic disruption and energy depletion in the parasite, which leads to its immobilisation. Thereby, COMBANTRIN A 400MG TABLET kills the susceptible helminth and treats the infection.
For neurocysticercosis, COMBANTRIN A 400MG TABLET is usually prescribed for 8-30 days. For cystic hydatid disease, COMBANTRIN A 400MG TABLET is usually prescribed for 28 days, followed by a 14 day break, and repeated for a total of 3 cycles.
Do not discontinue COMBANTRIN A 400MG TABLET without consulting your doctor. To treat your condition effectually continue taking COMBANTRIN A 400MG TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking COMBANTRIN A 400MG TABLET.
You are recommended to avoid planning for pregnancy while taking COMBANTRIN A 400MG TABLET as it may cause foetal harm. A pregnancy test should be done before starting the treatment with COMBANTRIN A 400MG TABLET, and women must use effective birth-control while taking COMBANTRIN A 400MG TABLET and for at least 1month after cessation of treatment.
Regular monitoring of blood count at the beginning of each cycle therapy and for every 2weeks while taking COMBANTRIN A 400MG TABLET is advised for all patients. Treatment with COMBANTRIN A 400MG TABLET should be discontinued if a significant decrease in blood cell count is observed.
Treatment with COMBANTRIN A 400MG TABLET has been associated with mild to moderate elevations of liver enzymes. These elevations generally return to normal upon discontinuation of COMBANTRIN A 400MG TABLET. Liver function tests should be performed before each treatment cycle and for every 2weeks during the treatment. Treatment with COMBANTRIN A 400MG TABLET should be discontinued if the liver enzymes exceed twice the upper limit of normal.
COMBANTRIN A 400MG TABLET might increase the chances of getting an infection. Maintain proper hygiene and try to stay away from people with infections, flu or cold.
You may bleed or bruise easily while taking COMBANTRIN A 400MG TABLET. Be cautious while using sharp objects and try to avoid injuries. Consult your doctor if you notice unusual bleeding or bruising.
You are recommended to avoid taking COMBANTRIN A 400MG TABLET if you allergic to COMBANTRIN A 400MG TABLET or any of its ingredients, if you are pregnant or planning pregnancy as it may cause foetal harm.
COMBANTRIN A 400MG TABLET should be used only under doctor’s supervision. Do not self-medicate as it can cause some severe side effects. Therefore, if you suspect worm infections in your kid, please consult a doctor.
Yes, COMBANTRIN A 400MG TABLET can cause diarrhea as a side effect. In such cases, drink lots of water or other fluids to stay hydrated. However, if diarrhea persists and you notice any signs of dehydration, such as reduced urination with strong-smelling and dark colored urine, consult your doctor. Do not take any other medications without your doctor’s advice.
No, taking COMBANTRIN A 400MG TABLET in more than the recommended dose will not make it more effective, rather it can increase the risk of severe side effects and toxicity. If the symptoms are not relieved by the recommended doses, please consult your doctor.
Store COMBANTRIN A 400MG TABLET at room temperature in a cool, dry and dark place. Protect from light. Keep it out of reach of children.
Yes, COMBANTRIN A 400MG TABLET can be taken with or without food or as advised by your doctor. Follow your doctor’s instructions.
The side effects of COMBANTRIN A 400MG TABLET include stomach pain, nausea, vomiting, headache and dizziness. If these side effects persist or worsen, please consult your doctor.
Yes, COMBANTRIN A 400MG TABLET may interact with praziquantel (anthelmintic), dexamethasone (corticosteroid), cimetidine (antacid), and theophylline (anti-asthma). Therefore, inform your doctor before taking COMBANTRIN A 400MG TABLET with other medicines to avoid possible interactions.

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