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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Combimist-L Respicap is used to treat or prevent chronic obstructive pulmonary disease (COPD). It contains Levosalbutamol and Ipratropium bromide, which work by relaxing muscles and widening the airways of the lungs. Some people may experience headaches, sore throat, dry mouth, tiredness, and vomiting. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Combimist-L Respicap

Combimist-L Respicap is used to treat or prevent symptoms of chronic obstructive pulmonary disease (COPD), like shortness of breath, coughing or wheezing (whistling sound while breathing).

Combimist-L Respicap contains Levosalbutamol and Ipratropium bromide, which work by relaxing muscles and widening the airways of the lungs. Thereby, it helps to breathe easily.

Combimist-L Respicap may cause headache, sore throat, dry mouth, runny or stuffy nose, pain, cough with mucus, dizziness, nervousness, tiredness, and vomiting. If the side effects persist or worsen, please consult your doctor.

Do not use Combimist-L Respicap if you are allergic to any of its components. If you are pregnant or breastfeeding, please consult a doctor. Keep your doctor informed about your health condition and medications to prevent any interactions.

Uses of Combimist-L Respicap

Combimist-L Respicap is used to treat chronic obstructive pulmonary disease (COPD). The detailed uses of Combimist-L Respicap are as follows:

  • Chronic Obstructive Pulmonary Disease (COPD): Combimist-L Respicap is used in the management of COPD, including chronic bronchitis and emphysema, to relieve breathing difficulty caused by airway narrowing.
  • Bronchospasm Relief: Provides quick and effective relief from bronchospasm (tightening of the muscles around the airways), helping reduce wheezing, coughing, and shortness of breath.
  • Add-on Therapy for Inadequate Response to Single Bronchodilator: Indicated for patients already using a regular bronchodilator but still experiencing symptoms, requiring a second bronchodilator for better control.
  • Improves Airflow in the Lungs: Helps to open up the airways, improving lung function and enhancing oxygen intake.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Hold the inhaler with the mouthpiece facing downwards. Form a tight seal by placing your lips around the mouthpiece. Start breathing slowly with your mouth and push down the inhaler once. Remove the inhaler and breathe normally.
  • Combimist-L Respicap is for inhalation purposes only.

Medicinal Benefits

  • Combimist-L Respicap helps open up the airways, making it easier to breathe for people with obstructive airway conditions.
  • It provides quick relief from wheezing, shortness of breath, chest tightness, and coughing caused by constricted airways.
  • It is effective in managing long-term lung diseases such as chronic bronchitis and emphysema.
  • Combimist-L Respicap contains Levosalbutamol (a beta-2 agonist) and Ipratropium Bromide (an anticholinergic), offering faster and more sustained bronchodilation than either drug alone.
  • It enhances oxygen intake and reduces airway resistance, improving overall respiratory performance.
  • Combimist-L Respicap helps reduce airway sensitivity to allergens, cold air, or exercise, preventing sudden respiratory distress.

How Combimist-L Respicap Works

Combimist-L Respicap is a combination of two bronchodilators: Levosalbutamol and Ipratropium bromide. It works by relaxing muscles and widening the airways of the lungs. Thereby, it allows us to breathe easily.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Combimist-L Respicap

An overdose of Combimist-L Respicap may cause high/low blood pressure, seizures, high heart rate, nervousness, headache, tremor, dry mouth, irregular heartbeat, nausea, dizziness, fatigue, malaise, and sleeplessness. If you have taken an overdose or notice these symptoms, please consult a doctor immediately.

Drug Warnings

  • Do not use Combimist-L Respicap if you are allergic to any of its components.
  • If you experience severe difficulty in breathing, please consult a doctor immediately.
  • Do not use Combimist-L Respicap in more than the prescribed doses, as it may lead to severe heart or lung problems.
  • Regular monitoring of potassium levels is recommended while taking Combimist-L Respicap , as it may cause low potassium levels in the blood.
  • If you experience irregular heartbeats, leg cramps, extreme thirst, constipation, increased urination, muscle weakness, numbness or tingling, please consult a doctor immediately, as these might be signs of low potassium.
  • If you have high blood pressure, diabetes, epilepsy (fits), enlarged prostate, glaucoma, thyroid or heart problems, bladder obstruction or other urinary problems, inform your doctor before starting Combimist-L Respicap .
  • Consult your doctor if you are pregnant or breastfeeding.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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SalbutamolPindolol
Severe

Drug-Drug Interactions

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SalbutamolPindolol
Severe
How does the drug interact with Combimist-L Respicap:
Using pindolol and Combimist-L Respicap together can increase the risk of narrowing of the airways.

How to manage the interaction:
The combined use of pindolol and Combimist-L Respicap can lead to an interaction, it can be taken if advised by your doctor. However, if you experience Coughing, wheezing, shortness of breath, and high-pitched breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Combimist-L Respicap:
Co-administration of Salbutaml with Labetalol, the effectiveness of Combimist-L Respicap might be reduced.

How to manage the interaction:
Although taking Labetalol and Combimist-L Respicap together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Combimist-L Respicap:
Coadministration of Carvedilol and Combimist-L Respicap may reduce the effects of both medications.

How to manage the interaction:
Although there is a possible interaction between Carvedilol and Combimist-L Respicap, they can be taken if your doctor advises. Consult your doctor if you experience shortness of breath, chest pain or any difficulties in breathing. Do not stop using any medications without a doctor's advice.
How does the drug interact with Combimist-L Respicap:
Co-administration of Combimist-L Respicap with timolol can increase the risk of narrowing of the airways.

How to manage the interaction:
Although taking Combimist-L Respicap and timolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience Coughing, wheezing, shortness of breath, and high-pitched breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
SalbutamolPenbutolol
Severe
How does the drug interact with Combimist-L Respicap:
Coadministration of Penbutolol and Combimist-L Respicap can reduce the effects of both medications and can cause narrowing of the airways.

How to manage the interaction:
Taking Penbutolol and Combimist-L Respicap can lead to an interaction, it can be taken if advised by your doctor. However, if you experience Coughing, wheezing, shortness of breath, and high-pitched breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Combimist-L Respicap:
The combined use of Papaverine and Combimist-L Respicap can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Papaverine and Combimist-L Respicap can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Combimist-L Respicap:
Using levobunolol and Combimist-L Respicap together can reduce the benefits of both drugs and can cause narrowing of the airways.

How to manage the interaction:
The combined use of levobunolol and Combimist-L Respicap can lead to an interaction, it can be taken if advised by your doctor. Don't forget to inform if you have any history of asthma, or severe chronic obstructive pulmonary disease (COPD), consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Combimist-L Respicap:
Using propranolol and Combimist-L Respicap together can reduce the effects or increase the risk of narrowing of the airways.

How to manage the interaction:
The combined use of propranolol and Combimist-L Respicap can lead to an interaction, but they can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Combimist-L Respicap:
Coadministration of mifepristone and Combimist-L Respicap can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Combimist-L Respicap with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in potassium, such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroots, as potassium is important for lung function and a potassium deficiency may cause breathing problems.
  • Drink plenty of fluids every day to thin mucus, which makes it easier to cough out.
  • Maintain a diet that includes complex carbohydrates such as lentils, beans, barley, oats, quinoa, bran, peas, and potatoes with skin.
  • Limit or avoid the intake of caffeinated drinks such as tea, coffee, soda, and energy drinks.
  • Eat protein-rich foods such as meat, fish (particularly salmon, sardines, and mackerel), eggs, and poultry.
  • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
  • Quit smoking as it may reduce the effectiveness of the Combimist-L Respicap and irritate the lungs, worsening breathing problems.

Habit Forming

No

Therapeutic Class

BRONCHODILATOR
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Alcohol

Caution

The interaction of Combimist-L Respicap with alcohol is unknown. Please consult a doctor before consuming alcohol with Combimist-L Respicap .

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Pregnancy

Caution

The safety of Combimist-L Respicap in pregnant women is unknown and is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Combimist-L Respicap is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Caution

Combimist-L Respicap may cause blurred vision or dizziness in some people. Therefore, avoid driving if you notice any changes in vision or feel dizzy after taking Combimist-L Respicap .

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Liver

Consult your doctor

If you have any concerns regarding the use of Combimist-L Respicap in patients with Liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Combimist-L Respicap in patients with Kidney problems, please consult a doctor.

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Children

Caution

Please consult a doctor before giving Combimist-L Respicap to children.

Have a query?

FAQs

Combimist-L Respicap is used to treat or prevent symptoms of chronic obstructive pulmonary disease (COPD), like shortness of breath, coughing or wheezing (whistling sound while breathing). It works by relaxing muscles and widening the airways of the lungs.

Combimist-L Respicap should be used with caution in diabetic patients if prescribed by a doctor. However, regular monitoring of blood sugar levels is recommended while taking Combimist-L Respicap as it may increase blood sugar levels.

Yes, Combimist-L Respicap may cause blurred vision in some patients. It is not necessary for everyone taking Combimist-L Respicap to experience this side effect. Therefore, avoid driving if you notice any changes in vision after taking Combimist-L Respicap .

Combimist-L Respicap should be used with caution in hyperthyroid (overactive thyroid) patients as it may worsen the condition. Inform your doctor if you have hyperthyroidism before taking Combimist-L Respicap so that the dose may be adjusted appropriately. However, regular monitoring of thyroid hormone levels is recommended while taking Combimist-L Respicap .

Yes, Combimist-L Respicap may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Combimist-L Respicap to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.

No, you are not recommended to stop taking Combimist-L Respicap without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Combimist-L Respicap for as long as your doctor has prescribed it, and if you experience any difficulty while taking Combimist-L Respicap , please consult your doctor.

No, Combimist-L Respicap does not relieve sudden symptoms such as shortness of breath. Therefore, it is advised to carry a rescue inhaler always to treat sudden symptoms.

No, Combimist-L Respicap is not a steroid. It is a combination medication that contains levosalbutamol and ipratropium bromide. These ingredients work together to help relax the air passages' muscles, making breathing easier. Combimist-L Respicap is commonly used to treat chronic obstructive pulmonary disease (COPD) and asthma.

Combimist-L Respicap may cause side effects such as headache, sore throat, dry mouth, and respiratory issues like cough, sneezing, and difficulty breathing. Other possible side effects include dizziness, nervousness, tiredness, irregular heartbeats, and vomiting. In most cases, these side effects are temporary and resolve on their own. However, if they persist or worsen, it's essential to consult your doctor for proper guidance.

Yes, Combimist-L Respicap nebulization is considered safe when used as prescribed by your doctor. It is commonly used to manage respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Combimist-L Respicap contains two active ingredients: ipratropium bromide and salbutamol, which work together to relax the airways' muscles, making breathing easier.

When taking Combimist-L Respicap , it's crucial to exercise caution with concomitant medications that may interact or exacerbate adverse effects. Certain medicines that stimulate the heart or increase blood pressure may potentiate the effects of Combimist-L Respicap , while others may counteract its therapeutic benefits. To ensure safe and effective treatment, consult your doctor for personalised guidance on potential medication interactions.

No, taking higher doses of Combimist-L Respicap will not necessarily make it more effective, and it can increase the risk of side effects like increased heart rate, tremors, and other complications. It is vital to use the medication exactly as prescribed by your doctor. If you feel that your current dosage is not providing adequate relief, consult your doctor for advice rather than adjusting the dose on your own.

No, Combimist-L Respicap is not typically known to cause sleepiness or drowsiness. However, individual reactions to medications can vary, and if you experience any unusual symptoms, it is essential to consult your doctor.

Store Combimist-L Respicap below 30°C. Please keep them in their original packaging to protect them from light and moisture. Do not freeze. Keep out of reach of children. Do not dispose of medications in household trash or wastewater. Follow local regulations for the disposal of medications.

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - COM0428

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