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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is used to treat and prevent respiratory disorders, such as asthma attacks and chronic obstructive pulmonary disease (COPD). It contains Salmeterol and Fluticasone, which relax the muscles in the airways and increase airflow to the lungs. It makes breathing easier by widening the airways. Also, it acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways. It may cause common side effects such as nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Combitide 25/125 mcg Starhaler Inhaler 120 mdi

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is a respiratory medication used to treat and prevent respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD). Asthma is a breathing disorder characterised by airway narrowing, swelling, and excessive mucus production, resulting in difficulty breathing. COPD is a group of lung diseases that includes emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of the bronchial tubes).

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is a combination of two medicines: Salmeterol and Fluticasone. Salmeterol is a long-acting bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone belongs to the class of corticosteroids. It acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.

Your doctor will advise on how often you take Combitide 25/125 mcg Starhaler Inhaler 120 mdi based on your medical condition. The common side effects of Combitide 25/125 mcg Starhaler Inhaler 120 mdi include nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Most of these side effects of Combitide 25/125 mcg Starhaler Inhaler 120 mdi do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own. Brief your medical history to the doctor if you have heart, liver, kidney diseases, hypokalaemia (low potassium levels in the blood), hyperadrenocorticism (high levels of cortisol), eye disorders like cataract and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes before taking Combitide 25/125 mcg Starhaler Inhaler 120 mdi. Therapy with nasal or inhaled corticosteroids like Fluticasone should be cautiously administered in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis, since there is a chance of developing a secondary infection. Please check with your doctor if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines.

Uses of Combitide 25/125 mcg Starhaler Inhaler 120 mdi

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is used to treat and prevent breathing problems associated with asthma and chronic obstructive pulmonary disease (COPD). The detailed uses of Combitide 25/125 mcg Starhaler Inhaler 120 mdi are as follows:
• Treatment of asthma: Used to relieve and prevent difficulty breathing, wheezing, shortness of breath, coughing, and chest tightness in people with asthma.
• Management of chronic obstructive pulmonary disease (COPD): Combitide 25/125 mcg Starhaler Inhaler 120 mdi controls and minimises symptoms such as wheezing, dyspnea, coughing, and chest tightness in patients with COPD, including chronic bronchitis and emphysema.
• Control of COPD flare-ups: Reduces the frequency and severity of COPD exacerbations while improving overall lung function.
• Anti-inflammatory effect: Fluticasone reduces airway irritation, which makes breathing easier.
• Long-acting bronchodilation: Salmeterol relaxes the airway muscles, helping breathing become easier over time.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Please read the instruction leaflet and use it as suggested by your doctor.
  • Rinse your mouth with water and spit it out after using Combitide 25/125 mcg Starhaler Inhaler 120 mdi to avoid fungal infections in the mouth and throat.

Medicinal Benefits

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is used to treat and prevent respiratory disorders, such as asthma attacks and chronic obstructive pulmonary disease (COPD). Combitide 25/125 mcg Starhaler Inhaler 120 mdi improves pulmonary function and effectively treats and prevents the worsening of emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Combitide 25/125 mcg Starhaler Inhaler 120 mdi is a combination of Salmeterol (bronchodilator) and Fluticasone (corticosteroid). Salmeterol relaxes the muscles in the airways, increasing airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways. Fluticasone has potent vasoconstrictive (narrowing of the blood vessels) and anti-inflammatory activity.

How Combitide 25/125 mcg Starhaler Inhaler 120 mdi Works

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is a combination of two medicines: Salmeterol (bronchodilator) and Fluticasone. Salmeterol is a long-acting bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone belongs to the class of corticosteroids. It acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Combitide 25/125 mcg Starhaler Inhaler 120 mdi

Do not use Combitide 25/125 mcg Starhaler Inhaler 120 mdi in more doses or more often than prescribed, as it may cause an overdose. The symptoms of overdose include chest pain, dry mouth, confusion, decreased urine output, loss of appetite, high blood pressure, nervousness or mood changes. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not stop taking this medicine on your own unless advised by your doctor. Before taking Combitide 25/125 mcg Starhaler Inhaler 120 mdi, let your doctor know if you have a history of heart, liver, kidney diseases, hyperadrenocorticism (high levels of cortisol), eye disorders like cataracts and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes. Combitide 25/125 mcg Starhaler Inhaler 120 mdi may cause hypokalemia (low potassium levels in the blood); therefore, it should be used with caution in patients with hypokalaemia to prevent any cardiovascular effects. Special precautions should be taken in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis, since nasal or inhaled corticosteroids like Fluticasone can cause secondary infections. Combitide 25/125 mcg Starhaler Inhaler 120 mdi can cause a rise in blood glucose levels. Hence, monitor your blood glucose levels regularly if you are diabetic. Please let your doctor know if you plan to become pregnant or are already pregnant and a lactating mother. Do not drive or operate machinery if you experience drowsiness and increased/uneven heart rate while using Combitide 25/125 mcg Starhaler Inhaler 120 mdi. Avoid drinking alcohol while taking this medicine, as it can worsen your side effects.

Drug-Drug Interactions

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SalmeterolCarteolol
Severe

Drug-Drug Interactions

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How does the drug interact with Combitide 25/125 mcg Starhaler Inhaler 120 mdi:
Co-administration of Combitide 25/125 mcg Starhaler Inhaler 120 mdi with Mifepristone may make Combitide 25/125 mcg Starhaler Inhaler 120 mdi less effective as a therapy.

How to manage the interaction:
Taking Combitide 25/125 mcg Starhaler Inhaler 120 mdi with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
SalmeterolCarteolol
Severe
How does the drug interact with Combitide 25/125 mcg Starhaler Inhaler 120 mdi:
The combined use of Carteolol and Combitide 25/125 mcg Starhaler Inhaler 120 mdi can reduce the effect of Combitide 25/125 mcg Starhaler Inhaler 120 mdi.

How to manage the interaction:
Taking Combitide 25/125 mcg Starhaler Inhaler 120 mdi with Carteolol together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Combitide 25/125 mcg Starhaler Inhaler 120 mdi:
Using sotalol together with Combitide 25/125 mcg Starhaler Inhaler 120 mdi may reduce the effects of both medications, which can lead to low treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between sotalol and Combitide 25/125 mcg Starhaler Inhaler 120 mdi, but it can be taken if prescribed by a doctor. If you experience any symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Combitide 25/125 mcg Starhaler Inhaler 120 mdi:
Taking Combitide 25/125 mcg Starhaler Inhaler 120 mdi with ritonavir can significantly increase the blood levels of Combitide 25/125 mcg Starhaler Inhaler 120 mdi.

How to manage the interaction:
There may be a possibility of interaction between Combitide 25/125 mcg Starhaler Inhaler 120 mdi and Ritonavir, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without talking to a doctor.
SalmeterolPenbutolol
Severe
How does the drug interact with Combitide 25/125 mcg Starhaler Inhaler 120 mdi:
The combined use of Penbutolol and Combitide 25/125 mcg Starhaler Inhaler 120 mdi can decrease the effect of both Combitide 25/125 mcg Starhaler Inhaler 120 mdi and Penbutolol. It may also increase the risk of severe asthma attacks or breathing problems.

How to manage the interaction:
Co-administration of Combitide 25/125 mcg Starhaler Inhaler 120 mdi with Penbutolol can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
SalmeterolIdelalisib
Severe
How does the drug interact with Combitide 25/125 mcg Starhaler Inhaler 120 mdi:
The combined use of Idelalisib and Combitide 25/125 mcg Starhaler Inhaler 120 mdi can increase the risk of irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Combitide 25/125 mcg Starhaler Inhaler 120 mdi and Idelalisib, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
How does the drug interact with Combitide 25/125 mcg Starhaler Inhaler 120 mdi:
Co-administration of Labetalol and Combitide 25/125 mcg Starhaler Inhaler 120 mdi together can decrease the medical benefits of both medications.

How to manage the interaction:
Although taking Labetalol and Combitide 25/125 mcg Starhaler Inhaler 120 mdi together can result in an interaction, it can be taken if a doctor has prescribed it. Do not forget to inform the doctor if you have severe chronic obstructive pulmonary disease (COPD) or a history of asthma, as labetalol is often not advised in these conditions. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Combitide 25/125 mcg Starhaler Inhaler 120 mdi:
When Ribociclib is taken with Combitide 25/125 mcg Starhaler Inhaler 120 mdi, it can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
There may be a possibility of interaction between Combitide 25/125 mcg Starhaler Inhaler 120 mdi and Ribociclib, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Combitide 25/125 mcg Starhaler Inhaler 120 mdi:
Taking Voriconazole may significantly increase the blood levels of Combitide 25/125 mcg Starhaler Inhaler 120 mdi. High blood levels of Combitide 25/125 mcg Starhaler Inhaler 120 mdi can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Voriconazole and Combitide 25/125 mcg Starhaler Inhaler 120 mdi together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, shortness of breath, or heart palpitations (irregular heartbeat), contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Combitide 25/125 mcg Starhaler Inhaler 120 mdi:
Taking Ketoconazole and Combitide 25/125 mcg Starhaler Inhaler 120 mdi (oral inhalation) together can increase the blood levels and effects of Combitide 25/125 mcg Starhaler Inhaler 120 mdi which may lead to a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ketoconazole and Combitide 25/125 mcg Starhaler Inhaler 120 mdi together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Combitide 25/125 mcg Starhaler Inhaler 120 mdi.
  • Know your triggers, such as allergens, such as pollen, dust, and food items, that make your asthma severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS
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Alcohol

Caution

Avoid drinking alcohol while taking this medicine as it can worsen your side effects.

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Pregnancy

Caution

Please consult your doctor if you are planning to conceive or are already pregnant before starting Combitide 25/125 mcg Starhaler Inhaler 120 mdi.

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Breast Feeding

Caution

There is limited data on how Combitide 25/125 mcg Starhaler Inhaler 120 mdi affects breastfeeding. Please consult your doctor before starting Combitide 25/125 mcg Starhaler Inhaler 120 mdi.

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Driving

Caution

Do not drive or operate machinery if you experience drowsiness and an increased or uneven heart rate while using Combitide 25/125 mcg Starhaler Inhaler 120 mdi. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Combitide 25/125 mcg Starhaler Inhaler 120 mdi should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Combitide 25/125 mcg Starhaler Inhaler 120 mdi.

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Kidney

Caution

Combitide 25/125 mcg Starhaler Inhaler 120 mdi should be used with caution in patients with kidney diseases. Inform your doctor if you have a history of kidney disease. Your doctor will weigh the benefits and potential risks before prescribing Combitide 25/125 mcg Starhaler Inhaler 120 mdi.

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Children

Caution

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is not recommended for use for children less than four years of age. The dose may have to be adjusted by your doctor depending upon the condition of the child's disease and age.

Have a query?

FAQs

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is used to treat and prevent respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD).

Combitide 25/125 mcg Starhaler Inhaler 120 mdi consists of Salmeterol (bronchodilator) and Fluticasone (Fluticasone). Salmeterol relaxes the muscles in the airways, increasing airflow to the lungs. Fluticasone acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways.

Combitide 25/125 mcg Starhaler Inhaler 120 mdi should be cautiously administered under the doctor's guidance in seizures since bronchodilators like Salmeterol can cause central nervous system stimulation that can lead to other adverse conditions. Please consult your doctor before using Combitide 25/125 mcg Starhaler Inhaler 120 mdi if you have seizures.

Combitide 25/125 mcg Starhaler Inhaler 120 mdi contains bronchodilator (Fluticasone), which can cause a rise in blood glucose levels. Hence, therapy with Combitide 25/125 mcg Starhaler Inhaler 120 mdi is cautiously administered in patients with diabetes. Please monitor your blood glucose levels regularly and inform your doctor so that the dose can be adjusted accordingly.

Bronchodilator (Salmeterol) in Combitide 25/125 mcg Starhaler Inhaler 120 mdi may decrease the potassium levels in your body; therefore, it should be used with caution. Please consult your doctor before taking Combitide 25/125 mcg Starhaler Inhaler 120 mdi since low potassium levels can lead to other cardiovascular problems in patients with hypokalaemia.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is a combination medication used to treat and prevent respiratory disorders, such as asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients: Salmeterol and Fluticasone Propionate.

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is a controller medication. It manages and prevents symptoms of asthma and chronic obstructive pulmonary disease (COPD) by keeping the airways open and reducing inflammation. It should be used regularly to be effective, and not to relieve sudden asthma attacks immediately.

Combitide 25/125 mcg Starhaler Inhaler 120 mdi contains a Fluticasone Propionate, which belongs to the family of medicines known as corticosteroids or steroids (cortisone-like medicines), which helps reduce inflammation in the airways.

Yes, Combitide 25/125 mcg Starhaler Inhaler 120 mdi may increase heart rate due to the Salmeterol component, which is a long-acting beta2-adrenergic receptor agonist (LABA). This can lead to palpitations, tremors, and increased heart rate in some individuals. Try deep breathing exercises, relaxation techniques, staying hydrated, and avoiding caffeine and nicotine to manage an increased heart rate. If the increased heart rate persists or worsens, consult your healthcare provider for guidance.

Combitide 25/125 mcg Starhaler Inhaler 120 mdi may cause some common side effects, including nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle, or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Most of these side effects of Combitide 25/125 mcg Starhaler Inhaler 120 mdi do not require medical attention and typically resolve on their own over time. However, if the side effects persist, contact your doctor.

Combitide 25/125 mcg Starhaler Inhaler 120 mdi is not addictive. It is a very effective and useful medication for people suffering from breathing difficulties due to asthma and COPD.

Taking Combitide 25/125 mcg Starhaler Inhaler 120 mdi more frequently than prescribed will not make it more effective and can increase the risk of side effects. It is essential to use this medication exactly as directed by your doctor to manage your asthma or COPD effectively.

When using Combitide 25/125 mcg Starhaler Inhaler 120 mdi, following certain precautions is essential to ensure safe and effective use. Follow your doctor's instructions, and do not use it for sudden asthma attacks. Instead, use a rescue inhaler as your doctor advises. Additionally, rinse your mouth with water after inhaling to prevent fungal infections. Avoid asthma triggers, such as dust, pollen, or smoke, and store the inhaler correctly, out of the reach of children, pets, and extreme temperatures. Inform your doctor about other medications, supplements, or vitamins you're taking, and regularly monitor for side effects, such as increased heart rate, tremors, or mood changes.

Combitide 25/125 mcg Starhaler Inhaler 120 mdi should be stored below 30°C and kept away from moisture. Keep out of the reach of children. Always follow the storage instructions provided on the packaging or by your healthcare provider.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001.
Other Info - COM0346

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