apollo
logo
0Login
Introducing Our Latest Arrival!
Combunex 800 Tablet 10's

Combunex 800 Tablet 10's

Not for online sale
Prescription drug
 Trailing icon
Consult Doctor

Manufacturer/Marketer

Lupin Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Combunex 800 Tablet

Combunex 800 Tablet belongs to the group of medications called ‘antituberculosis agents’ primarily used in the treatment of tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine and bone marrow. Combunex 800 Tablet does not work against infections caused by the virus.

Combunex 800 Tablet contains Isoniazid and Ethambutol. They are bacteriostatic agents (stop the growth of bacteria) and have a similar mode of action. They work by preventing mycolic acid production (an enzyme produced by bacteria) essential for cell wall formation (protective coating). Thereby, bacteria get killed without a cell wall and burst due to disruption in their metabolism.

Take Combunex 800 Tablet exactly as prescribed by the doctor. Combunex 800 Tablet may cause side effects such as weakness, malaise (general discomfort), fatigue (feeling tired), loss of appetite, nausea or vomiting, dark urine, pale stools, jaundice (yellowing of the skin or whites of the eyes) and vision problems. Inform your doctor immediately if any of these side effects persist or get worse.

It is not recommended to take Combunex 800 Tablet if you are allergic to any contents of it. Combunex 800 Tablet is not recommended for patients with severe liver problems and sight problems. Before taking Combunex 800 Tablet , inform your doctor if you have kidney problems, epilepsy (fits), diabetes, alcohol abuse, psychosis, malnourishment, HIV infection, and extra-pulmonary TB (TB infection outside the lungs). Combunex 800 Tablet should be used with caution in pregnant and breastfeeding women. Dose adjustments may be required in children and elderly people. Combunex 800 Tablet may interact with alcohol and increase the risk of liver damage. Combunex 800 Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Combunex 800 Tablet

Treatment of Tuberculosis

Medicinal Benefits

Combunex 800 Tablet contains Isoniazid and Ethambutol, which is a fixed-dose combination used to treat tuberculosis (TB). Combination therapy reduces the development of drug resistance (reduction in the effectiveness of medication) as the bacteria causing TB develops drug resistance easily when monotherapy is given even for shorter periods. Combunex 800 Tablet helps to reduce the symptoms and control the disease effectively.

Directions for Use

Take Combunex 800 Tablet on an empty stomach preferably at least one hour before breakfast or snack or after two hours of a meal. or take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Combunex 800 Tablet

  • Weakness
  • Malaise (general discomfort)
  • Fatigue (feeling tired)
  • Loss of appetite
  • Nausea or vomiting
  • Dark urine
  • Pale stools
  • Jaundice (yellowing of the skin or whites of the eyes)
  • Vision problems

Drug Warnings

It is advised to get your eyesight checked before taking Combunex 800 Tablet . If you notice any changes in your vision while using this medicine, stop taking this medicine and immediately inform your doctor. In most cases, the vision change is temporary and sight returns to normal. However, it might take a longer time for eyesight to recover in some cases or the change might be permanent. If you develop jaundice (yellowing of the skin and whites of the eyes), loss of appetite, nausea, vomiting, or malaise, inform your doctor immediately, as these effects may be a sign of hepatitis (liver disease). In these cases, the doctor may advise you to undergo liver function tests and provide the necessary treatment.

Drug Interactions

Drug-Drug Interactions: Combunex 800 Tablet may interact with antacid (aluminium hydroxide), anti-HIV drug (stavudine), medicines used to treat fits (carbamazepine, phenytoin, and primidone), a medicine used to treat alcoholism (disulfiram), other antitubercular drugs (rifampicin and para-aminosalicylic acid), an anti-anxiety medication (diazepam), a medicine used to treat Parkinson’s disease (levodopa), and antifungal drugs (itraconazole and ketoconazole).

Drug-Food Interactions: Avoid alcohol consumption with Combunex 800 Tablet as it may increase the risk of liver damage. Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, fish such as tuna, salmon, mackerel, wine and beer while taking Combunex 800 Tablet . The interaction of Combunex 800 Tablet with these foods may result in dizziness, headache, uneven heartbeat and flushing (reddening of the skin).

Drug-Disease Interactions: Combunex 800 Tablet is not recommended for use in patients with severe liver problems and eyesight problems. It should be used with caution in patients with kidney problems, epilepsy (fits), diabetes, alcohol abuse, psychosis, malnourishment, HIV infection and extra-pulmonary TB (TB infection outside the lungs).

Drug-Drug Interactions Checker List

  • ALUMINIUM HYDROXIDE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PRIMIDONE
  • DISULFIRAM
  • RIFAMPICIN
  • PARA-AMINOSALICYLIC ACID
  • DIAZEPAM
  • LEVODOPA
  • ITRACONAZOLE
  • KETOCONAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help improve the immune system.
  • Avoid processed and fried foods.
  • Stay hydrated. Drink plenty of fluids.
  • Warm ginger tea or warm soup can help in providing relief from cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, and fish such as tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

Special Advise

  • Patients with kidney problems should undergo kidney function tests before taking Combunex 800 Tablet .
  • Your doctor may monitor liver function and eyesight during the treatment with Combunex 800 Tablet .
  • Please do not stop taking this medicine abruptly as it may lead to withdrawal reactions such as headache, difficulty sleeping, irritability and nervousness.
  • Complete the full course of therapy even if you feel better or your symptoms improve.

Disease/Condition Glossary

Tuberculosis (TB): It is an infectious bacterial disease that affects the lungs, but it could also spread to other body parts such as kidneys, brain, spine, and bone marrow. Tuberculosis is caused by bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, and loss of appetite, and weight. People who smoke or consume alcohol, and people diagnosed with HIV and immune system problems are more likely at risk of developing active TB.

bannner image

Alcohol

Caution

Consumption of alcohol may increase the risk of side-effects and worsen the condition.

bannner image

Pregnancy

Caution

Combunex 800 Tablet should be used with caution in pregnant women. It is given to pregnant women only if clinically needed when the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Combunex 800 Tablet should be used with caution in breastfeeding mothers. It is given to breastfeeding mothers only when the benefits outweigh the risks.

bannner image

Driving

Caution

Combunex 800 Tablet may cause dizziness in some people. So, do not drive or operate heavy machinery if you are not fully alert.

bannner image

Liver

Caution

Combunex 800 Tablet is not recommended for patients with severe liver problems. In mild to moderate liver diseases, the dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Combunex 800 Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

bannner image

Children

Caution

Combunex 800 Tablet should be used with caution in children. The dose may have to be adjusted based on age, body weight and healthy history of the child.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info -

FAQs

Combunex 800 Tablet is used in the treatment of tuberculosis (TB).
Combunex 800 Tablet contains Isoniazid and Ethambutol. They are bacteriostatic agents (stop the growth of bacteria) and have a similar mode of action. They work by preventing mycolic acid production (an enzyme produced by bacteria) essential for cell wall formation (protective coating, which is necessary for bacteria's survival).
It is advised to take Combunex 800 Tablet on an empty stomach. So, you should take this medicine at least 30 minutes before a meal or after 2 hours of taking a meal for better absorption.
You are recommended to avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, fish such as tuna, salmon and mackerel, wine and beer as they may interact with Combunex 800 Tablet and cause adverse effects such as sweating, headache, dizziness, flushing (reddening of the skin) and uneven heartbeat.
Combunex 800 Tablet may cause side-effects such as weakness, malaise (general discomfort), fatigue (feeling tired), loss of appetite, nausea or vomiting, dark urine, pale stools, jaundice (yellowing of the skin or whites of the eyes) and vision problems. Inform your doctor immediately if any of these side-effects persist or get worse.
Combunex 800 Tablet may affect liver function, so it is not prescribed in patients with severe liver problems and alcohol abuse unless clinically needed. Also, do not consume excessive amounts of alcohol while using Combunex 800 Tablet as it may increase the risk of liver damage.
Yes, ethambutol in Combunex 800 Tablet may rarely cause vision problems like blurred/decreased vision, color blindness. Consult your doctor immediately if there is a problem in vision.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.