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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Comcapsy 400 mg/20 mg Tablet

Comcapsy 400 mg/20 mg Tablet belongs to a group of medications called 'antineoplastic agents,' primarily used to treat metastatic breast cancer. Cancer occurs when cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissues and may sometimes spread to other areas of the body (known as metastasis).

Comcapsy 400 mg/20 mg Tablet contains two anticancer medications: Capecitabine (an antimetabolite) and Cyclophosphamide (an alkylating agent). Both drugs exhibit potential synergistic effects; Cyclophosphamide boosts the activity of an enzyme (thymidine phosphorylase) that helps convert Capecitabine into its active form, 5-fluorouracil. They work by damaging the genetic material of cancer cells to stop their growth and multiplication. Thus, Comcapsy 400 mg/20 mg Tablet helps treat cancer by killing cancer cells.

You are advised to take Comcapsy 400 mg/20 mg Tablet for as long as your doctor has prescribed it, depending on your medical condition. In some cases, you may experience common side effects, such as nausea, vomiting, loss of appetite, diarrhoea, stomach pain, skin rash, weakness, tiredness, mouth sores, hair loss, fever, low blood cell count, and hand-foot syndrome (swelling, redness, and peeling on palms and soles). If you experience any of these side effects, do not hesitate to report them clearly to your doctor.

Do not use Comcapsy 400 mg/20 mg Tablet if you are allergic to any of its ingredients, fluorouracil, other cancer medicines, or have severe kidney disease or bladder obstruction. Inform your doctor before taking Comcapsy 400 mg/20 mg Tablet if you had treatment with chemotherapy and radiation or have certain medical conditions, including metabolic disorders, chronic infection, a weakened immune system, urination problems, or heart, lung, liver, or kidney diseases. Tell your doctor if you are taking any blood thinners (warfarin) before using Comcapsy 400 mg/20 mg Tablet , as it may increase the risk of severe bleeding. Avoid taking Comcapsy 400 mg/20 mg Tablet if you are pregnant or breastfeeding, as it may cause harmful effects on the baby. Comcapsy 400 mg/20 mg Tablet may cause dizziness or vision problems, so avoid driving and operating machines until you are fully alert.

Uses of Comcapsy 400 mg/20 mg Tablet

Comcapsy 400 mg/20 mg Tablet is used to treat metastatic breast cancer. The detailed uses of Comcapsy 400 mg/20 mg Tablet are as follows:<br/>• Manages advanced breast cancer: Comcapsy 400 mg/20 mg Tablet helps slow the growth and spread of cancer that has metastasized beyond the breast.<br/>• Reduces tumor size: Comcapsy 400 mg/20 mg Tablet works by interfering with cancer cell division, helping shrink tumors.<br/>• Supports combination therapy: Comcapsy 400 mg/20 mg Tablet is often used along with other anticancer treatments to improve overall effectiveness.<br/>

Directions for Use

• Take Comcapsy 400 mg/20 mg Tablet within 30 minutes after meals or as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Swallow Comcapsy 400 mg/20 mg Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Comcapsy 400 mg/20 mg Tablet is an anticancer medication primarily used to treat metastatic breast cancer. It is also used in combination with other medicines to treat various types of cancer, as advised by a doctor, including colorectal, colon, stomach, pancreatic, and ovarian cancer. It contains Capecitabine (an antimetabolite) and Cyclophosphamide (an alkylating agent). Both work by damaging the genetic material of cancer cells to stop their growth and multiplication. Thus, Comcapsy 400 mg/20 mg Tablet effectively treats cancer by killing cancer cells.

How Comcapsy 400 mg/20 mg Tablet Works

Comcapsy 400 mg/20 mg Tablet contains two anticancer medications: Capecitabine (an antimetabolite) and Cyclophosphamide (an alkylating agent). Both drugs exhibit potential synergistic effects; Cyclophosphamide boosts the activity of an enzyme (thymidine phosphorylase) that helps convert Capecitabine into its active form, 5-fluorouracil. They work by damaging the genetic material of cancer cells to stop their growth and multiplication. Thus, Comcapsy 400 mg/20 mg Tablet helps treat cancer by killing cancer cells.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Comcapsy 400 mg/20 mg Tablet

Avoid exceeding the recommended dose of Comcapsy 400 mg/20 mg Tablet , as it may lead to an overdose. Symptoms of an overdose may include nausea, vomiting, diarrhoea, stomach pain, unusual bleeding or bruising, weakness, tiredness, red-coloured urine, tarry stools, and signs of infection (fever, sore throat, cough). If you experience any of these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Comcapsy 400 mg/20 mg Tablet if you are allergic to any of its ingredients, fluorouracil, other cancer medicines, or have severe kidney disease or bladder obstruction. Tell your doctor if you are taking prescription or non-prescription medications, vitamins, or herbal supplements to rule out any side effects and interactions. Additionally, inform your doctor before taking Comcapsy 400 mg/20 mg Tablet if you had treatment with chemotherapy and radiation or have certain medical conditions, including metabolic disorders (such as dihydropyrimidine dehydrogenase deficiency), chronic infection, a weakened immune system, decreased bone marrow function (such as leukopenia, anaemia, thrombocytopenia), dehydration, urination problems, or heart, lung, liver, or kidney diseases. Tell your doctor if you are taking any blood thinners (warfarin) before using Comcapsy 400 mg/20 mg Tablet , as it may increase the risk of severe bleeding. Exercise caution when using sharp objects like nail cutters and razors to minimize the risk of injury or bruising. Avoid taking Comcapsy 400 mg/20 mg Tablet if you are pregnant or breastfeeding, as it may cause harmful effects on the baby. Use birth control pills while taking Comcapsy 400 mg/20 mg Tablet and for 6 months after your last dose to prevent pregnancy. Comcapsy 400 mg/20 mg Tablet should be used with caution in elderly patients over 60 years. Comcapsy 400 mg/20 mg Tablet may cause dizziness or vision problems, so avoid driving and operating machines until you are fully alert.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Comcapsy 400 mg/20 mg Tablet:
Co-administration of Nalidixic acid with Comcapsy 400 mg/20 mg Tablet may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of Comcapsy 400 mg/20 mg Tablet and Nalidixic acid can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Comcapsy 400 mg/20 mg Tablet:
Co-administration of Comcapsy 400 mg/20 mg Tablet and Cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclophosphamine with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor
How does the drug interact with Comcapsy 400 mg/20 mg Tablet:
Coadministration of Tenofovir disoproxil with Comcapsy 400 mg/20 mg Tablet may increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction, Comcapsy 400 mg/20 mg Tablet can be taken with Tenofovir disoproxil if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medication without consulting a doctor.
How does the drug interact with Comcapsy 400 mg/20 mg Tablet:
Taking Comcapsy 400 mg/20 mg Tablet with Tofacitinib may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Comcapsy 400 mg/20 mg Tablet can be taken with Tofacitinib if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Comcapsy 400 mg/20 mg Tablet:
Using baricitinib together with Comcapsy 400 mg/20 mg Tablet may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, Baricitinib can be taken with Comcapsy 400 mg/20 mg Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Comcapsy 400 mg/20 mg Tablet:
Taking Comcapsy 400 mg/20 mg Tablet with Thalidomide may increase the risk of blood clots.

How to manage the interaction:
Although there is a possible interaction, Comcapsy 400 mg/20 mg Tablet can be taken with Thalidomide if prescribed by the doctor. However, consult the doctor if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness, or swelling in an arm or leg. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Comcapsy 400 mg/20 mg Tablet:
Co-administration of Golimumab with Comcapsy 400 mg/20 mg Tablet may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Comcapsy 400 mg/20 mg Tablet with Golimumab can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination. Do not stop using any medications without a doctor's advice.
CyclophosphamideRopivacaine
Severe
How does the drug interact with Comcapsy 400 mg/20 mg Tablet:
Co-administration of Ropivacaine with Comcapsy 400 mg/20 mg Tablet can cause methemoglobinemia (low levels of oxygen in the blood).

How to manage the interaction:
Although there is a possible interaction between Ropivacaine and Comcapsy 400 mg/20 mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
CyclophosphamideCertolizumab
Severe
How does the drug interact with Comcapsy 400 mg/20 mg Tablet:
When Comcapsy 400 mg/20 mg Tablet is taken with Certolizumab, may increase the risk or severity of infections.

How to manage the interaction:
There may be a possibility of interaction between Comcapsy 400 mg/20 mg Tablet and Certolizumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Comcapsy 400 mg/20 mg Tablet:
Co-administration of Comcapsy 400 mg/20 mg Tablet and Deferiprone may increase the risk of serious and potential infections.

How to manage the interaction:
Co-administration of Comcapsy 400 mg/20 mg Tablet with Deferiprone can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Incorporate leafy vegetables, fatty fish, citrus fruits, yogurt, berries, apples, cauliflower, peaches, cabbage, broccoli, beans, herbs, and spices into your diet.
  • Avoid fast foods, fried foods, processed meats, refined carbs, and added sugar.
  • Avoid smoking and excessive alcohol consumption.
  • Exercise at least 30 minutes on most days of the week.
  • Maintain a healthy weight and seek professional advice for weight loss.
  • Get enough sleep and rest for effective recovery.
  • Ask your doctor about when to start breast cancer screening and perform breast self-exams to notice any changes or lumps.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Comcapsy 400 mg/20 mg Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

It is unknown whether alcohol interacts with Comcapsy 400 mg/20 mg Tablet . However, it is advisable not to consume alcohol as a precautionary measure.

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Pregnancy

Unsafe

Comcapsy 400 mg/20 mg Tablet should not be used during pregnancy, as it may cause harmful effects on the baby. You are advised to avoid pregnancy by using birth control pills during treatment with Comcapsy 400 mg/20 mg Tablet and for 6 months after your last dose.

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Breast Feeding

Unsafe

Comcapsy 400 mg/20 mg Tablet should not be taken during breastfeeding, as it passes into the breast milk and may harm the baby. You are advised to stop breastfeeding during treatment with Comcapsy 400 mg/20 mg Tablet and for 2 weeks after your last dose.

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Driving

Caution

Comcapsy 400 mg/20 mg Tablet may cause dizziness and vision problems. Therefore, avoid driving and operating machines until you are fully alert.

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Liver

Caution

Comcapsy 400 mg/20 mg Tablet may sometimes cause harm to the liver or increase bilirubin levels in the blood. If you have a history of liver disease, please inform your doctor before taking Comcapsy 400 mg/20 mg Tablet . Your doctor may need to adjust the dose of Comcapsy 400 mg/20 mg Tablet .

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Kidney

Caution

Comcapsy 400 mg/20 mg Tablet may sometimes cause harm to the kidney. If you have a history of kidney disease, please inform your doctor before taking Comcapsy 400 mg/20 mg Tablet . Your doctor may need to adjust the dose of Comcapsy 400 mg/20 mg Tablet .

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Children

Unsafe

Comcapsy 400 mg/20 mg Tablet should not be used by children under 12 years, as its safety and effectiveness have not been established in this age group.

Have a query?

FAQs

Comcapsy 400 mg/20 mg Tablet is an anticancer medication primarily used to treat metastatic breast cancer. It is also used in combination with other medicines to treat various types of cancer, as advised by a doctor, including colorectal, colon, stomach, pancreatic, and ovarian cancer.

Comcapsy 400 mg/20 mg Tablet contains two anticancer medications: Capecitabine (an antimetabolite) and Cyclophosphamide (an alkylating agent). Both drugs exhibit potential synergistic effects; Cyclophosphamide boosts the activity of an enzyme (thymidine phosphorylase) that helps convert Capecitabine into its active form, 5-fluorouracil. They work by damaging the genetic material of cancer cells to stop their growth and multiplication. Thus, Comcapsy 400 mg/20 mg Tablet helps treat cancer by killing cancer cells.

Comcapsy 400 mg/20 mg Tablet may cause common side effects such as nausea, vomiting, loss of appetite, diarrhoea, stomach pain, skin rash, weakness, tiredness, mouth sores, hair loss, fever, low blood cell count, and hand-foot syndrome (swelling, redness, and peeling on palms and soles). If you experience any of these side effects, do not hesitate to report them clearly to your doctor. Your doctor may suggest lifestyle changes, medications, and supportive therapies to help reduce discomfort and improve your quality of life.

Do not stop taking Comcapsy 400 mg/20 mg Tablet on your own without consulting your doctor, as it can affect your treatment and recovery. You are advised to take Comcapsy 400 mg/20 mg Tablet for as long as your doctor has prescribed it, depending on your medical condition, for effective treatment of cancer.

Yes, Comcapsy 400 mg/20 mg Tablet may impair fertility by temporarily stopping sperm production in men and disrupting normal menstrual periods in women. Therefore, consult your doctor for advice before taking Comcapsy 400 mg/20 mg Tablet if you are planning to have a child. Also, it is important to use birth control pills while taking Comcapsy 400 mg/20 mg Tablet and for 6 months after your last dose to prevent pregnancy.

Comcapsy 400 mg/20 mg Tablet might cause myelosuppression (reduced bone marrow function) leading to a decrease in white blood cells. This could lead to an increased risk of infections. You are advised to get regular blood tests while taking Comcapsy 400 mg/20 mg Tablet .

Yes, Comcapsy 400 mg/20 mg Tablet contains two chemotherapy medicines: Capecitabine, which is an antimetabolite, and Cyclophosphamide, which is an alkylating agent. They work by destroying cancer cells.

Comcapsy 400 mg/20 mg Tablet may cause weight loss due to decreased appetite and may also be a result of the underlying cancer. Please consult your doctor if you experience significant weight loss while using Comcapsy 400 mg/20 mg Tablet .

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - COM0667

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