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compositionComposition:XANTINOL NICOTINATE-500MG
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Prescription Medicine
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Complamina Retard 500 Tablet is used to improve circulatory conditions like peripheral vascular diseases and cerebrovascular disorders. It contains Xantinol nicotinate which works by widening blood vessels and increasing blood flow. In some cases, this medicine may cause side effects such as headache, dizziness, stomach upset, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

XANTINOL NICOTINATE-500MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Complamina Retard 500 Tablet

Complamina Retard 500 Tablet is a medicine prescribed to improve blood circulation, especially in the limbs and brain. It helps treat conditions caused by narrowed or blocked blood vessels, which restrict proper blood flow to vital tissues. By relaxing and widening these vessels, it ensures your body's tissues receive an adequate supply of oxygen and essential nutrients.

To get the best results, you must take Complamina Retard 500 Tablet consistently at the same times every day as directed by your doctor. It is usually best to take this medicine right after a meal with a full glass of water to reduce stomach discomfort or sudden skin warmth. Making healthy lifestyle choices, such as staying physically active and avoiding cold drafts, can further enhance your circulation.

Many people experience mild, temporary warmth, flushing, or tingling shortly after taking a dose, which typically decreases as their body gets used to the medicine. However, you should contact your doctor immediately if you experience persistent dizziness, severe skin rashes, or a rapid, irregular heartbeat.

Before starting Complamina Retard 500 Tablet , talk to your doctor if you have a history of stomach ulcers, gout, gallbladder issues, or liver problems. Do not take this if you have active bleeding, a recent heart attack, or suffer from severe low blood pressure.

Certain medicines, alcohol, and tobacco can interfere with how this medicine works. For instance, drinking alcohol while taking this medicine can cause a sudden, sharp drop in blood pressure. If you are pregnant, breastfeeding, an older adult, have kidney disease, or are considering this medicine for a child, talk to your doctor or pharmacist before use. The safety of Complamina Retard 500 Tablet in children has not been established. 

Uses of Complamina Retard 500 Tablet

Complamina Retard 500 Tablet is used to help improve blood circulation in conditions caused by reduced blood flow. The detailed uses of Complamina Retard 500 Tablet are as follows:

  • Peripheral vascular disease: It helps widen narrowed blood vessels in the legs and arms, reducing painful cramps and coldness in the hands and feet.
  • Cerebral circulatory disorders: It improves blood flow to the brain, helping manage symptoms like dizziness or memory difficulties linked to poor circulation.
  • Diabetic vascular complications: It assists in maintaining healthy blood circulation to tissues that have been damaged by long-term high blood sugar levels.

Key Benefits

Taking Complamina Retard 500 Tablet as prescribed may provide the following benefits:

  • Relieves leg pain during walking: It helps relieve the painful, tight cramping in your calves and legs that often happens when you walk or exercise. By restoring healthy blood circulation, it allows you to walk longer distances without discomfort, helping you regain your physical independence and stay active.
  • Improves circulation to the hands and feet: For those who suffer from constantly cold, numb, or tingling fingers and toes, this medicine brings reassuring warmth and sensitivity back to your extremities. It helps protect your skin and delicate tissues from the long-term damage caused by chronically poor blood flow. 

Directions for Use

  • It is recommended to take Complamina Retard 500 Tablet with food to prevent stomach upset or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Complamina Retard 500 Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Complamina Retard 500 Tablet Works

Complamina Retard 500 Tablet works by relaxing the smooth muscles in the walls of your blood vessels, causing them to widen. This process allows blood to flow more freely and easily throughout your body. Additionally, Xantinol nicotinate helps reduce blood viscosity (the resistance of blood to flow) and improves the flexibility of red blood cells, allowing them to pass more easily through narrow or partially blocked blood vessels. These effects improve blood flow but are different from the action of anticoagulant (blood-thinning) medicines. This dual action significantly increases oxygen delivery to tissues that are starved of blood.
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Alcohol

Caution

It is advised to limit alcohol intake since alcohol consumption with Complamina Retard 500 Tablet may increase the risk of low blood pressure.

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Pregnancy

Caution

It is not known if Complamina Retard 500 Tablet affects pregnancy. Consult your doctor before taking Complamina Retard 500 Tablet if you plan to become pregnant or already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Complamina Retard 500 Tablet .

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Breast Feeding

Caution

There is no evidence on how Complamina Retard 500 Tablet affects breastfeeding. Please consult your doctor before taking Complamina Retard 500 Tablet if you are breastfeeding.

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Driving

Caution

Complamina Retard 500 Tablet may cause side effects like dizziness, headaches, nausea or tiredness, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Complamina Retard 500 Tablet . Dose adjustments may be required.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Complamina Retard 500 Tablet . Dose adjustments may be required.

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Children

Caution

Complamina Retard 500 Tablet should be used in children only when prescribed by a doctor.

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Heart

Unsafe

Complamina Retard 500 Tablet is generally not recommended for heart patients due to an increased risk of side effects.

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Geriatrics

Caution

Complamina Retard 500 Tablet should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform a healthcare professional before use.

What if I have taken an overdose of Complamina Retard 500 Tablet

If you suspect an overdose or experience severe dizziness, intense flushing, or fainting, seek immediate medical attention or call emergency services right away.

Diet & Lifestyle Advise

  • Avoid smoking and tobacco use: Nicotine constricts blood vessels, directly opposing the beneficial effects of Complamina Retard 500 Tablet .
  • Stay active with gentle exercise: Regular, moderate walking can train your muscles to use oxygen more efficiently and improve your overall circulation.
  • Keep your hands and feet warm: Wear warm socks and gloves in cold weather to protect your extremities from sudden blood vessel spasms.
  • Stay well-hydrated: Drink plenty of water throughout the day to support healthy blood volume and smooth circulation.
  • Inspect your feet daily: If you have poor circulation in your legs, check your feet daily for cuts, sores, or redness, as healing can be slower.
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How Soon It Starts Working

The time required for Complamina Retard 500 Tablet to start to work: Complamina Retard 500 Tablet ideally shows its action within 30 minutes to an hour after administration. The time for which the effects of Complamina Retard 500 Tablet last: The duration of action for Complamina Retard 500 Tablet is clinically unknown.

What if you forget to take Complamina Retard 500 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Complamina Retard 500 Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the medication in its original blister pack or bottle to protect it from direct light and moisture.

Drug Warnings

  • Anticipate the flushing effect: Expect a warm, tingling sensation shortly after taking the dose; this is normal, harmless, and usually decreases after a few days of consistent use.
  • Rise slowly from lying or sitting positions: To prevent sudden dizziness or lightheadedness, take your time when standing up.
  • Monitor your blood pressure regularly: Since this medicine widens blood vessels, it can lower your blood pressure, especially if you take other heart medications.
  • Limit heat exposure: Avoid very hot baths, saunas, or prolonged sun exposure, as heat can worsen flushing and dizziness.
  • Inform your surgeon: Tell your doctor or dentist that you take Complamina Retard 500 Tablet before any planned surgical or dental procedures, as it affects blood flow.

Drug-Drug Interactions

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nform your doctor if you are taking any of the following medicines, as they may interact.

  • Blood pressure-lowering medicines: Combining Complamina Retard 500 Tablet with drugs used to treat high blood pressure (such as beta-blockers or ACE inhibitors) may cause your blood pressure to drop too low, leading to dizziness.
  • Vasodilators (other blood vessel dilators): Taking this with other vasodilators can intensify side effects like flushing and lightheadedness.
  • Blood thinners: Use caution if you take medicines that prevent blood clots, as the combination may increase your risk of bleeding.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Alcohol: Avoid alcohol as it can cause sudden, severe widening of blood vessels, significantly increasing the risk of low blood pressure and extreme flushing.
  • Hot beverages: Avoid drinking very hot tea, coffee, or soups immediately after taking your dose, as heat can intensify the skin-flushing effect.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Complamina Retard 500 Tablet is used to improve peripheral vascular diseases (a circulatory disorder where blood flow to the limbs is decreased due to constricted blood vessels) and cerebrovascular disorders (a group of conditions that affect blood flow and the blood vessels in the brain).
Complamina Retard 500 Tablet consists of Xantinol Nicotinate, a vasodilator. It widens the blood vessels, improving the blood supply to the limbs and brain. Thus, Complamina Retard 500 Tablet helps improve peripheral vascular diseases and cerebrovascular disorders.
Complamina Retard 500 Tablet can make you feel dizzy. Dizziness usually occurs when you suddenly stand up from a lying or sitting position. Try rising slowly when you change your posture to relieve dizziness. If the side effect persists longer, please seek medical help.
Please inform your doctor if you are taking Complamina Retard 500 Tablet and need to undergo any surgery. Your doctor may ask you to stop using Complamina Retard 500 Tablet or prescribe any alternate medication because blood pressure may be further lowered if taken along with general anaesthesia.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage. Do not double the dose.
Do not stop using Complamina Retard 500 Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.
Complamina Retard 500 Tablet is safe when used as prescribed by a doctor. Follow your doctor's instructions and inform of any unusual symptoms or side effects you experience while taking Complamina Retard 500 Tablet .
The common side effects of Complamina Retard 500 Tablet include flushing, headache, dizziness, nausea, vomiting, diarrhea, abdominal pain, skin rash, and itching. These side effects may occur in some cases, but not all individuals will experience them. If any of these side effects persist or worsen, please consult your doctor.
This is a common and harmless reaction called flushing. It happens because the medicine widens the small blood vessels near your skin, increasing blood flow. This sensation usually fades within a few hours and decreases as your body gets used to the medicine. Talk to your doctor if it becomes unbearable.
It is highly recommended to take Complamina Retard 500 Tablet right after a meal. Taking it with food helps protect your stomach from irritation and can significantly reduce the intensity of the temporary skin flushing and warmth. Talk to your doctor or pharmacist if you have questions about how to take your dose.
You can drink coffee or tea, but it is best to avoid hot drinks immediately before or after taking your dose. Hot liquids can trigger or worsen the temporary warming and flushing side effect of this medicine. Talk to your doctor or pharmacist for personalised advice.
Complamina Retard 500 Tablet is a niacin (nicotinic acid) derivative and is generally well tolerated when used at prescribed doses. Although liver problems are more commonly associated with high-dose niacin therapy, your doctor may recommend periodic liver function tests during long-term treatment or if you have existing liver disease. If you notice yellowing of your skin or eyes, dark urine, or persistent abdominal pain, talk to your doctor immediately.
This medicine can sometimes cause temporary dizziness or lightheadedness, especially when you first start taking it. It is safest to see how your body reacts to the medication before driving or operating machinery. Talk to your doctor if you experience persistent dizziness.
For most people, the flushing effect gets milder over a few days or weeks. If the flushing remains intense, itchy, or highly uncomfortable, do not stop taking your medicine suddenly. Instead, talk to your doctor, who may suggest gradually increasing the dose schedules to help your body adapt.
The safety of this medicine during pregnancy has not been fully established. It should only be used if your doctor determines that the benefits outweigh the potential risks to the baby. Talk to your doctor or pharmacist before starting this medicine if you are pregnant or planning to become pregnant.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.
Other Info - COM0022
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