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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Coversyl-AM 4/10 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure and stable coronary artery disease. It also helps reduce the chances of heart problems such as heart attack and stroke. It is a combination medicine which suppress the contraction of blood vessels and promote smooth blood flow. It also alters the response to nerve impulses in the heart thereby making the heart pump blood easier. Common side effects include oedema, headache, dizziness, nausea, and abdominal pain.
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Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Coversyl-AM 4/10 Tablet

Coversyl-AM 4/10 Tablet is used to treat high blood pressure (hypertension). Additionally, it is also used to treat stable coronary artery disease. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Stable coronary artery disease is a condition in which the blood supply to the heart is blocked or reduced.
 
Coversyl-AM 4/10 Tablet is a combination of two drugs: Amlodipine and Perindopril erbumine. Amlodipine relaxes the blood vessels, thereby improving blood flow. Perindopril erbumine widens the blood vessels, making it easier for the heart to pump blood through them. Together, Coversyl-AM 4/10 Tablet helps lower the blood pressure, thereby reduces the chances of heart problems such as heart attack and stroke.  
 
You are advised to take Coversyl-AM 4/10 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as oedema, headache, dizziness, nausea, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Coversyl-AM 4/10 Tablet is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Coversyl-AM 4/10 Tablet is not recommended for breastfeeding mothers and children. Coversyl-AM 4/10 Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Coversyl-AM 4/10 Tablet

Treatment of Hypertension (high blood pressure), stable coronary artery disease

Directions for Use

Take Coversyl-AM 4/10 Tablet before a meal. Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Coversyl-AM 4/10 Tablet is a combination of two drugs: Amlodipine and Perindopril erbumine. Coversyl-AM 4/10 Tablet belongs to the group of anti-hypertensive medicines used to treat high blood pressure (hypertension) and/or stable coronary artery disease. Amlodipine is a calcium channel blocker that relaxes the blood vessels, thereby improving blood flow. Perindopril erbumine is an angiotensin-converting enzyme inhibitor that widens the blood vessels; this makes it easier for the heart to pump blood through them. Together, Coversyl-AM 4/10 Tablet helps treat hypertension, thereby reducing the chances of heart problems such as heart attack and stroke.

How Coversyl-AM 4/10 Tablet Works

Coversyl-AM 4/10 Tablet is a combination of two drugs: Amlodipine and Perindopril erbumine. Amlodipine relaxes the blood vessels, thereby improving blood flow. Perindopril erbumine widens the blood vessels, making it easier for the heart to pump blood through them. Together, Coversyl-AM 4/10 Tablet helps lower the blood pressure, thereby reduces the chances of heart problems such as heart attack and stroke.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Coversyl-AM 4/10 Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include fast/slow heartbeat, severe dizziness, and fainting. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Coversyl-AM 4/10 Tablet if you are allergic to any of its contents; if you have angioedema, severe water retention, low blood pressure, or low blood potassium. Inform your doctor if you have diabetes, heart problems, gout, parathyroid gland problems, heart failure, collagen disease, atherosclerosis (hardening of arteries), excess acid in the blood, liver/kidney problems, if you are on a low-salt diet, if you are taking lithium/potassium-sparing diuretics, or if you are taking any other blood pressure-lowering medicines. Coversyl-AM 4/10 Tablet is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Coversyl-AM 4/10 Tablet is not recommended for breastfeeding mothers and children. Coversyl-AM 4/10 Tablet may cause dizziness, so drive with caution. Keep your doctor informed about your health condition and medications to rule out any interactions.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Coversyl-AM 4/10 Tablet:
Using Coversyl-AM 4/10 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Coversyl-AM 4/10 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Coversyl-AM 4/10 Tablet:
Combining Aliskiren with Coversyl-AM 4/10 Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Coversyl-AM 4/10 Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coversyl-AM 4/10 Tablet:
Using Coversyl-AM 4/10 Tablet and phenytoin together may drastically lower Coversyl-AM 4/10 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Coversyl-AM 4/10 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coversyl-AM 4/10 Tablet:
Using phenobarbital and Coversyl-AM 4/10 Tablet may drastically lower Coversyl-AM 4/10 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Coversyl-AM 4/10 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Coversyl-AM 4/10 Tablet:
Coadministration of Coversyl-AM 4/10 Tablet and Rifapentine may significantly reduce the blood levels of Coversyl-AM 4/10 Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Coversyl-AM 4/10 Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Coversyl-AM 4/10 Tablet:
Coadministration of Ceritinib together with Coversyl-AM 4/10 Tablet can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Coversyl-AM 4/10 Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Coversyl-AM 4/10 Tablet:
Using a combination of Coversyl-AM 4/10 Tablet and enzalutamide may drastically lower Coversyl-AM 4/10 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Coversyl-AM 4/10 Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coversyl-AM 4/10 Tablet:
Coadministration of Coversyl-AM 4/10 Tablet and rifampicin together may lower Coversyl-AM 4/10 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Coversyl-AM 4/10 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coversyl-AM 4/10 Tablet:
Coadministration of Coversyl-AM 4/10 Tablet and carbamazepine together may significantly reduce Coversyl-AM 4/10 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Coversyl-AM 4/10 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Coversyl-AM 4/10 Tablet:
Coadministration of lemborexant and Coversyl-AM 4/10 Tablet may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Coversyl-AM 4/10 Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-10MG+PERINDOPRIL ERBUMINE-4MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-10MG+PERINDOPRIL ERBUMINE-4MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Coversyl-AM 4/10 Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Coversyl-AM 4/10 Tablet.

Diet & Lifestyle Advise

  • You are advised to consume low salt and low-fat diet. 

  • Regular exercise is also recommended.

  • Eat a diet rich in whole grains, vegetables, and fruits.

  • Avoid smoking and alcohol consumption.

  • Maintain a healthy weight with proper diet and exercise.

  • Practice meditation or yoga as it helps in managing stress.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Caution

Avoid consuming alcohol as it might cause increased dizziness.

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Pregnancy

Unsafe

Coversyl-AM 4/10 Tablet is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Please consult your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Coversyl-AM 4/10 Tablet is not recommended for breastfeeding mothers. Talk to your doctor if you have any concerns.

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Driving

Caution

Coversyl-AM 4/10 Tablet may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver problems or any concerns regarding this. Avoid taking Coversyl-AM 4/10 Tablet if you have severe liver disease or hepatic encephalopathy.

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Kidney

Caution

Dose adjustment may be needed. Avoid taking Coversyl-AM 4/10 Tablet if you have severe kidney problems. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Coversyl-AM 4/10 Tablet is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

Coversyl-AM 4/10 Tablet is used to treat high blood pressure (hypertension). Additionally, it is also used to treat stable coronary artery disease.

Coversyl-AM 4/10 Tablet contains Amlodipine and Perindopril erbumine. Amlodipine relaxes the blood vessels, thereby improving blood flow. Perindopril erbumine widens the blood vessels; this makes it easier for the heart to pump blood through them. Together, Coversyl-AM 4/10 Tablet helps treat high blood pressure.

Coversyl-AM 4/10 Tablet may cause palpitations, a sensation that the heart is racing, pounding, or fluttering. A minor fluctuation should not be a worry; however, if palpitations continue or you begin to feel unwell, speak with your doctor.

High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, and kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Coversyl-AM 4/10 Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.

Do not stop taking Coversyl-AM 4/10 Tablet without consulting your doctor, as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Coversyl-AM 4/10 Tablet for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Coversyl-AM 4/10 Tablet .

Light-headedness could be a side-effect of Coversyl-AM 4/10 Tablet . It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Coversyl-AM 4/10 Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

Avoid consuming grapefruit and grapefruit juice whilst taking Coversyl-AM 4/10 Tablet as it might increase the blood levels of amlodipine; this can lead to an unpredictable increase in the blood pressure-lowering effect of Coversyl-AM 4/10 Tablet . Inform your doctor if you are on a salt-restricted diet, use salt substitutes or if you are taking potassium supplements.

Country of origin

India

Manufacturer/Marketer address

Serdia House, Off Dr. S S Rao Road, Behind M G Hospital Parel, Mumbai 400012
Other Info - COV0050

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