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  3. CPZ-100 Tablet 10's

CPZ-100 Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

CPZ-100 Tablet is used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Besides this, it is also used to treat nausea and vomiting, anxiety before surgery, and chronic hiccups (involuntary spasms of the diaphragm). It contains Chlorpromazine, which acts by blocking dopamine, a neurotransmitter present in the brain responsible for developing schizophrenia and bipolar disorder symptoms. It rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substances receptors in the brain, such as histamine and muscarinic receptors, thereby preventing nausea and vomiting. In some cases, you may experience certain common side effects such as sleepiness, orthostatic hypotension (sudden lowering of blood pressure on standing), dry mouth, abnormality of voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor.

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Composition :

CHLORPROMAZINE-100MG

Manufacturer/Marketer :

A N Pharmacia Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About CPZ-100 Tablet

CPZ-100 Tablet is used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Besides this, it is also used to treat nausea and vomiting, anxiety before surgery, and chronic hiccups (involuntary spasms of the diaphragm). Schizophrenia is characterised by hallucination symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). Manic episodes of excitement or depression characterise bipolar disorder. CPZ-100 Tablet prevents the occurrence of these symptoms. 

CPZ-100 Tablet contains ‘Chlorpromazine’, which is an antipsychotic drug. It acts by blocking dopamine, a neurotransmitter present in the brain responsible for developing schizophrenia and bipolar disorder symptoms. CPZ-100 Tablet  rebalances dopamine to improve thinking, mood, and behaviour. It also blocks the other natural substances receptors in the brain, such as histamine and muscarinic receptors, thereby preventing nausea and vomiting.

Take CPZ-100 Tablet as prescribed by your doctor. You are advised to take CPZ-100 Tablet as prescribed by your doctor, depending on your medical condition. In some cases, you may experience certain common side effects, such as sleepiness, orthostatic hypotension (sudden lowering of blood pressure upon standing), dry mouth, abnormality of voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremors. Most of these side effects of CPZ-100 Tablet do not require medical attention and typically resolve on their own over time. However, if these side effects persist longer, please consult your doctor.

Do not take CPZ-100 Tablet if you are allergic to Chlorpromazine or any other ingredients present in it. Before taking CPZ-100 Tablet , talk to your doctor if you or your family have a history of blood clots, stroke, or heart disease, or if you are above 65 years and have a history of dementia (memory loss). CPZ-100 Tablet is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking CPZ-100 Tablet . It is not recommended for use in children under 1 year of age. Please do not stop taking CPZ-100 Tablet without your doctor’s advice, as it may lead to withdrawal symptoms.

Uses of CPZ-100 Tablet

CPZ-100 Tablet is used in the treatment of schizophrenia and other psychotic disorders. The detailed uses of CPZ-100 Tablet are as follows:<br/> • Psychotic Disorders: CPZ-100 Tablet is used to treat acute and chronic psychoses, including schizophrenia, paranoia (feelings of distrust and suspicion), and mania or hypomania in bipolar disorder (manic depression). It helps reduce symptoms such as increased energy, decreased need for sleep, and hyperexcitability.<br/> • Behavioural disturbances: CPZ-100 Tablet is used in the short-term management of agitation and anxiety. It also helps calm down aggressive or impulsive behaviour.<br/> • Chronic (Intractable) Hiccups: CPZ-100 Tablet may be prescribed for the relief of persistent or severe hiccups that last more than 48 hours.<br/> • Nausea and Vomiting: CPZ-100 Tablet is effective in controlling nausea (feeling sick) or vomiting (being sick), especially in terminal illness when other medications have failed.<br/> • Pre-operative Anxiety: CPZ-100 Tablet helps relieve restlessness and nervousness before surgery.<br/> • Acute Intermittent Porphyria (AIP): CPZ-100 Tablet helps manage symptoms associated with AIP, such as abdominal pain, anxiety, and mood changes.<br/> • Tetanus: CPZ-100 Tablet is used in conjunction with other medications to manage the symptoms of tetanus, including spasms and muscle rigidity.<br/> • Hypothermia Induction: In rare cases, CPZ-100 Tablet is used to lower body temperature during specific medical or surgical procedures intentionally.<br/> • Use in Paediatric Patients: CPZ-100 Tablet is used under strict medical supervision to treat schizophrenia, autism (difficulties in learning and social communication), and attention-deficit hyperactivity disorder (a condition marked by hyperactivity, inattention, and impulsivity) in children.<br/>

Directions for Use

  • CPZ-100 Tablet can be taken with or without food, as advised by your doctor.
  • Your doctor will determine the dosage and timing of this medication based on your medical condition.
  • Swallow CPZ-100 Tablet as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Medicinal Benefits

CPZ-100 Tablet works by helping to restore the balance of certain natural substances in the brain. The key action of CPZ-100 Tablet is to block the dopamine receptors (D2) in the brain and correct dopamine's overactivity. Altogether, CPZ-100 Tablet may help decrease hallucinations and help you think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. On the other hand, it also blocks histamine H1 and muscarinic M1 receptors in the vomiting centre, thereby preventing nausea and vomiting.

How CPZ-100 Tablet Works

CPZ-100 Tablet contains Chlorpromazine, which is an antipsychotic drug. It acts by blocking dopamine, a neurotransmitter present in the brain responsible for developing schizophrenia and bipolar disorder symptoms. CPZ-100 Tablet  rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substances receptors in the brain, such as histamine and muscarinic receptors, thereby preventing nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of CPZ-100 Tablet
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Maintain good hygiene by washing with lukewarm water regularly.
  • Moisturize your skin to keep it hydrated.
  • Practice wearing loose-fitting clothes made from breathable fabrics.
  • Apply cool compresses by using a damp cloth on the rashes for few minutes.
  • Avoid scratching on rashes to prevent infections.
  • Consider covering the rashes by using a gauge.
  • Take cool baths and add baking soda or oatmeal bath products to ease itching.
  • Tell your doctor if you notice any unusual symptoms after taking the medication, such as flat purple, or red spots on your skin.
  • Your doctor may change your medication, lower the dose, or stop the treatment to help manage the symptoms.
  • Avoid heavy physical activity and get plenty of rest to prevent further worsening of the symptoms.
  • Apply cold packs to the affected areas for relief.
  • Drink plenty of fluids to stay hydrated, and eat fruits and vegetables or take supplements to get enough vitamins.
  • Over-the-counter pain relievers can help with discomfort.
  • Regularly wash your hands with alcohol-based sanitizer or soap and water.
  • Also, avoid sharing personal items like glasses or utensils with other individuals.
  • If you experience significant changes in body temperature or symptoms like fever, altered mental status, excessive sweating, or feeling unusually cold or hot, while taking a medicine, consult your doctor and discuss about discontinuing the suspected medicine.
  • Remove excess clothing and apply cool compresses to the groin, armpits and neck.
  • Make use of cool air blowing devices or misting fans.
  • In severe cases, consider ice water immersion or a cooling blanket.
  • Avoid using antipyretics (fever reducers) as they are not effective in managing drug-induced hyperthermia (body temperature is higher than normal).
  • Consult your doctor if temperature is not lowered by cooling measures.

What if I have taken an overdose of CPZ-100 Tablet

Do not take more than the prescribed dose of CPZ-100 Tablet , as it may cause an overdose. The symptoms of an overdose include low body temperature, drowsiness, low blood pressure, stiffness, shaking, twisting of your limbs, unusual heartbeats, and coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take CPZ-100 Tablet if you are allergic (hypersensitive) to any ingredients present in it. Please consult your doctor before taking CPZ-100 Tablet if you are pregnant, planning to conceive, or breastfeeding. The use of CPZ-100 Tablet should be avoided in children and adolescents whose signs and symptoms suggest Reye’s syndrome (confusion, swelling in the brain, and liver damage). Elderly patients (above 65 years) with dementia-related psychosis (memory loss) treated with antipsychotic drugs increased the risk of death. Do not abruptly stop taking the medication, as it may cause withdrawal symptoms, especially suicidal thoughts in young adults. Before taking CPZ-100 Tablet , talk to your doctor if you have a history of blood clots, alcohol or drug abuse, fits (seizures), Parkinson's disease, hypothyroidism (reduced activity of the thyroid gland), stroke or heart diseases, myasthenia gravis (a condition where muscles become easily tired and weak leading to difficulty breathing) and glaucoma (increased pressure in the eye).

Drug-Drug Interactions

verifiedApollotooltip
ChlorpromazineCisapride
Critical
ChlorpromazineSparfloxacin
Critical

Drug-Drug Interactions

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ChlorpromazineCisapride
Critical
How does the drug interact with CPZ-100 Tablet:
Taking CPZ-100 Tablet with Cisapride can increase the risk of a abnormal heart rhythm.

How to manage the interaction:
Taking CPZ-100 Tablet with Cisapride is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlorpromazineSparfloxacin
Critical
How does the drug interact with CPZ-100 Tablet:
Using CPZ-100 Tablet together with sparfloxacin can increase the risk of side effects.

How to manage the interaction:
Taking Sparfloxacin with CPZ-100 Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChlorpromazineThioridazine
Critical
How does the drug interact with CPZ-100 Tablet:
Taking Thioridazine and CPZ-100 Tablet can increase the effects of serious side effects.

How to manage the interaction:
Taking CPZ-100 Tablet with Thioridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience extreme drowsiness, confusion, irritation, vomiting, vision problem, feeling hot or cold, sweating, muscle stiffness, fainting, seizure, uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs, fever, muscle rigidity, irregular heart beat, consult the doctor. Do not discontinue any medications without consulting a doctor.
ChlorpromazinePhenobarbital
Critical
How does the drug interact with CPZ-100 Tablet:
When CPZ-100 Tablet is taken with Phenobarbital, can change the drug levels and effects of both medications.

How to manage the interaction:
Taking CPZ-100 Tablet with Phenobarbital is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual symptoms, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlorpromazineZiprasidone
Critical
How does the drug interact with CPZ-100 Tablet:
Taking CPZ-100 Tablet with Ziprasidone can increase the risk of a serious abnormal heart rhythm.

How to manage the interaction:
Taking CPZ-100 Tablet with Ziprasidone is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChlorpromazineDronedarone
Critical
How does the drug interact with CPZ-100 Tablet:
Taking CPZ-100 Tablet with Dronedarone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking CPZ-100 Tablet with Dronedarone is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlorpromazineMesoridazine
Critical
How does the drug interact with CPZ-100 Tablet:
Taking CPZ-100 Tablet with Mesoridazine together can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking CPZ-100 Tablet with Mesoridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChlorpromazineEliglustat
Critical
How does the drug interact with CPZ-100 Tablet:
When CPZ-100 Tablet and Eliglustat are taken together, the effect of CPZ-100 Tablet is reduced.

How to manage the interaction:
Taking CPZ-100 Tablet with Eliglustat is not recommended, as it can possibly result in an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChlorpromazineCitalopram
Severe
How does the drug interact with CPZ-100 Tablet:
Taking CPZ-100 Tablet and citalopram together can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking CPZ-100 Tablet and citalopram together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor. Do not discontinue any medications without first consulting your doctor.
ChlorpromazineSotalol
Severe
How does the drug interact with CPZ-100 Tablet:
Using CPZ-100 Tablet together with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking CPZ-100 Tablet and Sotalol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Monitor your mood. Regularly track your mood, including factors such as sleep, medication, and activities that can affect it.
  • Exercise daily to avoid the weight gain that can be a side effect of bipolar medication.
  • Practice calming techniques such as meditation and deep breathing exercises.
  • Get enough sleep to help stabilise your mood.
  • Eat a healthy diet. Certain foods may have a greater impact on your mood than others. Consider keeping a food log to track what you eat and how specific foods affect your well-being. Consult with your doctor or a nutritionist about foods that may help stabilise your mood.
  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.
  • Eating a healthy diet that includes plenty of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products can help maintain good health and reduce the risk of nausea and vomiting.
  • One should avoid taking greasy or oily foods, as this food triggers nausea and vomiting.
  • Eat cool foods instead of hot and spicy foods.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks to replenish the fluid that has been lost due to vomiting.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

CPZ-100 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Alcohol may worsen the condition and increase the risk of side effects while using CPZ-100 Tablet .

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Pregnancy

Caution

CPZ-100 Tablet is a category C pregnancy drug. It may affect the unborn baby. Please consult your doctor before taking CPZ-100 Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Caution

CPZ-100 Tablet is known to be passed through breast milk. So, it is recommended not to take CPZ-100 Tablet during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if the benefits outweigh the risks.

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Driving

Unsafe

CPZ-100 Tablet may cause drowsiness, dizziness, and light-headedness. If you are affected, do not drive or operate machinery after taking CPZ-100 Tablet .

bannner image

Liver

Consult your doctor

CPZ-100 Tablet should be used with caution in patients with liver diseases. Dose adjustment may be necessary.

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Kidney

Consult your doctor

CPZ-100 Tablet should be used with caution in patients with kidney diseases. Dose adjustment may be necessary.

bannner image

Children

Caution

CPZ-100 Tablet is not recommended for children below 1 year of age. However, please consult a doctor before giving CPZ-100 Tablet to children.

Have a query?

FAQs

CPZ-100 Tablet is used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Besides this, it may also be used to treat nausea and vomiting, anxiety before surgery, and chronic hiccups (involuntary spasms of the diaphragm).

CPZ-100 Tablet works by blocking dopamine receptors in the brain. By inhibiting the synthesis of the dopamine hormone, there will be a decrease in the occurrence of symptoms in patients with schizophrenia and bipolar depression.

You are not recommended to stop taking CPZ-100 Tablet without consulting your doctor. It may cause withdrawal symptoms such as palpitations (the sensation that the heart skipped a beat or an extra beat), anxiety, confusion, difficulty sleeping and tremors. Therefore, take CPZ-100 Tablet for as long as your doctor has prescribed it. If you experience any difficulty while taking CPZ-100 Tablet , please consult your doctor so that the dose can be gradually reduced.

CPZ-100 Tablet is not recommended for patients suffering from myasthenia gravis (severe muscle weakness) as it may worsen the condition. Therefore, inform your doctor if you have myasthenia gravis before taking CPZ-100 Tablet .

Long-term use of CPZ-100 Tablet may cause dyskinesia (a movement disorder) in some cases. However, your doctor will prescribe this medication if the benefits outweigh the risks.

CPZ-100 Tablet can decrease anxiety, irritability or agitation. However, you should consult a doctor before using CPZ-100 Tablet .

No, CPZ-100 Tablet is not a benzodiazepine or a sleeping tablet. It belongs to the class of medications called antipsychotics. However, consult your doctor if you have any concerns.

No, CPZ-100 Tablet is not a controlled substance/ narcotic. However, a doctor's prescription is required to purchase it.

No, CPZ-100 Tablet does not have a high potential for addiction. However, take CPZ-100 Tablet as prescribed by your doctor.

You are recommended to take the advice of your doctor because it is not the primary treatment for opiate withdrawal.

The common side effects of CPZ-100 Tablet are sleepiness, orthostatic hypotension (low blood pressure), dry mouth, abnormal voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremors. Most of these side effects of CPZ-100 Tablet do not require medical attention and typically resolve on their own over time. However, if these side effects persist longer, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - CPZ0001

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 21, 2025 | 1:43 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drreddys.com/media/109808/chlorpromazine-25-50-100-pil.pdf
  2. https://www.drugs.com/mtm/chlorpromazine.html
  3. https://www.medicines.org.uk/emc/files/pil.3476.pdf
  4. https://www.medicines.org.uk/emc/files/pil.957.pdf
  5. https://mhraproducts4853.blob.core.windows.net/docs/81137defce2bcb675b224a754346839a074d8fc7
  6. https://pdf.hres.ca/dpd_pm/00018580.PDF

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