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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cregnex 7.5K Injection is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Cregnex 7.5K Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Whats That

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Synonym :

POLYMYXIN B SULPHATE

Manufacturer/Marketer :

Converge Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Cregnex 7.5K Injection

Cregnex 7.5K Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Cregnex 7.5K Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Cregnex 7.5K Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Cregnex 7.5K Injection. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Cregnex 7.5K Injection

Treatment of Bacterial infections

Directions for Use

Cregnex 7.5K Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Cregnex 7.5K Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Cregnex 7.5K Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

How Cregnex 7.5K Injection Works

Cregnex 7.5K Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Cregnex 7.5K Injection

As Cregnex 7.5K Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Cregnex 7.5K Injection if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Cregnex 7.5K Inj:
Taking Kanamycin with Cregnex 7.5K Inj can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Cregnex 7.5K Inj and Kanamycin, but it can be taken if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Cregnex 7.5K Inj:
Co-administration of Cregnex 7.5K Inj may increase the effects of Suxamethonium when taken in combination.

How to manage the interaction:
Co-administration of Suxamethonium with Cregnex 7.5K Inj can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cregnex 7.5K Inj:
Coadministration of Amikacin with Cregnex 7.5K Inj may increase the risk of severe side effects.

How to manage the interaction:
Although taking Amikacin and Polymyxin- b together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience ringing in the ears, difficulty breathing, vomiting, irregular urination, swelling, muscle pain, dizziness, or palpitation. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cregnex 7.5K Inj:
Taking Tenofovir alafenamide with Cregnex 7.5K Inj can increase the chance of side effects.

How to manage the interaction:
Taking Tenofovir alafenamide with Cregnex 7.5K Inj together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Cregnex 7.5K Inj:
Coadministration of Tenofovir disoproxil with Cregnex 7.5K Inj can increase the risk of side effects.

How to manage the interaction:
Taking Tenofovir disoproxil with Cregnex 7.5K Inj together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Cregnex 7.5K Inj:
Co-administration of Cregnex 7.5K Inj and Vecuronium together may cause serious breathing problems.

How to manage the interaction:
Taking Cregnex 7.5K Inj with Vecuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing difficulty, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bBacitracin
Severe
How does the drug interact with Cregnex 7.5K Inj:
Taking Cregnex 7.5K Inj and Bacitracin together can increase the risk of kidney and inner ear damage

How to manage the interaction:
Although taking Cregnex 7.5K Inj and Bacitracin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience ringing in the ears, hearing loss, vertigo, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Cregnex 7.5K Inj:
Co-administration of Sirolimus and Cregnex 7.5K Inj together may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Sirolimus and Cregnex 7.5K Inj, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Cregnex 7.5K Inj:
Co-administration of Deferasirox and Cregnex 7.5K Inj may increase the risk of kidney problems.

How to manage the interaction:
Although taking Cregnex 7.5K Inj and Deferasirox together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, swelling, breathing difficulty, bone pain, muscle pain, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
Polymyxin bCholera, live attenuated
Severe
How does the drug interact with Cregnex 7.5K Inj:
Taking Cregnex 7.5K Inj and Cholera together may lead to a decrease in the effectiveness of the vaccine.

How to manage the interaction:
There may be a possibility of interaction between Cregnex 7.5K Inj and Cholera, live attenuated, but it can be taken if prescribed by a doctor. It is advised not to receive the cholera vaccination until at least 14 days after finishing your Cregnex 7.5K Inj therapy in order to ensure an appropriate immune response. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Cregnex 7.5K Injection. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Cregnex 7.5K Injection.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Cregnex 7.5K Injection. Caution is advised while administering Cregnex 7.5K Injection to lactating women.

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Driving

Consult your doctor

It is unknown if Cregnex 7.5K Injection affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Cregnex 7.5K Injection.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Cregnex 7.5K Injection.

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Children

Safe if prescribed

Cregnex 7.5K Injection may be safe for use in children if prescribed by the doctor.

Have a query?

FAQs

Cregnex 7.5K Injection is used to treat Bacterial infections.

Cregnex 7.5K Injection works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Diarrhoea might be a side effect of Cregnex 7.5K Injection. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.

Cregnex 7.5K Injection may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.

Cregnex 7.5K Injection will be administered by a healthcare professional. Do not self-administer.

Yes, Cregnex 7.5K Injection is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.

The common side effects of Cregnex 7.5K Injection may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

7-2-1813,/5/A/1, Vasavi'S Central Court, Unit-Ii , 3Rd Floor, Czech Colony, Sanath Nagar, Hyderabad - 500018., Telangana State, India.
Other Info - CRE0250

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