apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:DARBEPOETIN ALFA-100MCG
prescription
Prescription Medicine
info
image icons

Cresp+100 PFS Injection 0.5 ml is used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). It helps to reverse anaemia and reduce the need for blood transfusion. It contains Darbepoetin alfa, which works by providing signals to the bone marrow to make more red blood cells. In chronic kidney disease, when the kidney fails to produce sufficient erythropoietin protein that aids in the formation of red blood cells, this medicine stimulates the production of this protein in the bone marrow. It may cause common side effects such as shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain.

Read more
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
Get Extra 18% Off with Coupons
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

DARBEPOETIN ALFA-100MCG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Cresp+100 PFS Injection 0.5 ml

Cresp+100 PFS Injection 0.5 ml is an injectable medicine prescribed to treat anaemia, which is a condition characterised by a low red blood cell count. It is commonly used for patients with long-term kidney disease or those receiving chemotherapy for certain types of cancer. By helping your body produce more red blood cells, this treatment reduces the severe tiredness and weakness associated with anaemia.

This medicine is injected either under the skin or directly into a vein, and it must be used consistently as scheduled by your healthcare provider. Your food intake does not affect how this medicine works, but eating a balanced diet rich in iron can support your body's red blood cell production. Regularly monitoring your nutritional intake helps achieve the best results from your treatment.

While using Cresp+100 PFS Injection 0.5 ml, some people may experience common side effects like headaches or mild discomfort at the injection site. However, if you develop serious symptoms such as sudden shortness of breath, chest pain, or a severe headache, you must contact your doctor immediately. Do not delay seeking medical care if you experience these issues.

Before starting Cresp+100 PFS Injection 0.5 ml, tell your doctor if you have a history of high blood pressure, heart disease, stroke, or seizures. Do not take this if you have uncontrolled high blood pressure or if you have ever developed a condition called pure red cell aplasia (a severe stop in red blood cell production) after using similar medicines.

Certain medications, such as those that suppress your immune system, can interact with this injection, so provide your doctor with a complete list of your current medicines. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, talk to your doctor or pharmacist to ensure this treatment is safe for your specific situation.

Uses of Cresp+100 PFS Injection 0.5 ml

Cresp+100 PFS Injection 0.5 ml is used to treat anaemia. The detailed uses of Cresp+100 PFS Injection 0.5 ml are as follows:

  • Anaemia due to chronic kidney disease: Cresp+100 PFS Injection 0.5 ml helps by stimulating your body to produce more red blood cells, which prevents severe fatigue and weakness caused by failing kidneys.
  • Anaemia due to chemotherapy: For patients undergoing cancer treatments, this injection helps rebuild red blood cell levels that have been lowered by chemotherapy drugs.
     

Key Benefits

Cresp+100 PFS Injection 0.5 ml helps treat anaemia by stimulating your body to produce more red blood cells, improving oxygen delivery to your tissues. With regular treatment, it helps restore energy levels, reduces the need for blood transfusions, and makes everyday activities easier by easing symptoms of low red blood cell counts.

  • Improves energy and reduces fatigue: By increasing the oxygen-carrying red blood cells in your body, this medicine helps reduce the constant tiredness and weakness associated with anaemia.
  • Reduces the need for blood transfusions: By encouraging your body to naturally make its own red blood cells, it lowers the frequency of requiring external blood transfusions.
  • Supports daily activities: Improved red blood cell counts mean your muscles and organs get the oxygen they need, helping you manage your daily routine with less physical strain.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Cresp+100 PFS Injection 0.5 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Cresp+100 PFS Injection 0.5 ml Works

Cresp+100 PFS Injection 0.5 ml contains darbepoetin alfa. It works by mimicking the action of a natural hormone in your body called erythropoietin, which is produced by healthy kidneys. This hormone sends a signal to your bone marrow, the soft tissue inside your bones, to produce more red blood cells. When kidneys are damaged or when chemotherapy suppresses bone marrow function, your body cannot produce enough of this hormone, leading to anaemia. When you inject Cresp+100 PFS Injection 0.5 ml, it binds to specific receptors in the bone marrow, triggering the division and growth of red blood cells. This safely and gradually increases your red blood cell count, helping your body transport oxygen more efficiently.
bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking Cresp+100 PFS Injection 0.5 ml as it may increase dizziness and sleepiness.

bannner image

Pregnancy

Caution

Avoid taking Cresp+100 PFS Injection 0.5 ml if you are pregnant unless prescribed by a doctor as Cresp+100 PFS Injection 0.5 ml is a pregnancy category C drug. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Consult your doctor before taking Cresp+100 PFS Injection 0.5 ml; your doctor will decide whether Cresp+100 PFS Injection 0.5 ml can be taken by breastfeeding mothers or not.

bannner image

Driving

Unsafe

Cresp+100 PFS Injection 0.5 ml causes convulsions (seizures), especially during the initial months of treatment. So, it is better not to drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Cresp+100 PFS Injection 0.5 ml should not be given to children as the safety and efficacy have not been established.

bannner image

Heart

Unsafe

Cresp+100 PFS Injection 0.5 ml is not recommended for use in cardiac patients due to the cardiovascular effects.

bannner image

Geriatrics

Consult your doctor

Cresp+100 PFS Injection 0.5 ml can be given in geriatric patients if prescribed by the physician.

What if I have taken an overdose of Cresp+100 PFS Injection 0.5 ml

If you suspect an overdose or have injected too much of this medicine, seek immediate medical attention or call an emergency helpline. An overdose can cause your red blood cell count to rise too quickly, which can lead to serious heart or blood vessel complications.

Diet & Lifestyle Advise

  • Eat iron-rich foods: To make red blood cells, your body needs plenty of iron. Include foods like red meat, beans, lentils, spinach, and iron-fortified cereals in your meals.
  • Check your iron levels: Your doctor may recommend taking an iron supplement. Ensure you take it exactly as prescribed, as Cresp+100 PFS Injection 0.5 ml cannot work effectively if your body's iron stores are low.
  • Monitor your blood pressure: Because this medicine can raise your blood pressure, check it regularly at home and keep a log for your doctor.
  • Avoid dehydration: Drink plenty of water throughout the day to support healthy blood circulation.
health query

Have a query?

How Soon It Starts Working

The time required for Cresp+100 PFS Injection 0.5 ml to start to work: The time required for Cresp+100 PFS Injection 0.5 ml to show its action is unknown. The time for which the effects of Cresp+100 PFS Injection 0.5 ml last: The duration of action for Cresp+100 PFS Injection 0.5 ml is unknown.

What if you forget to take Cresp+100 PFS Injection 0.5 ml

If you miss a dose, contact your doctor or pharmacist immediately to get a rescheduled timing. Do not inject a double dose to make up for a missed one.

Storage

• Store Cresp+100 PFS Injection 0.5 ml in a refrigerator between 2°C and 8°C. • Do not freeze the medicine, and do not use it if it has been frozen.

Drug Warnings

  • Never shake the vial or syringe, as vigorous shaking can damage the medicine and make it ineffective.
  • Do not use the medicine if you notice any cloudiness, discolouration, or floating particles in the liquid.
  • Always change the location where you inject the medicine each time to prevent skin irritation or thickening.
  • Keep all appointments for blood tests, as your doctor needs to check your haemoglobin levels regularly to ensure your dose is safe and effective.
  • Avoid driving or operating machinery if you feel dizzy or experience headaches after your injection.

verifiedApollotooltip
  • Cyclosporine: This medicine binds to red blood cells. When used together, your doctor may need to monitor your blood levels of cyclosporine and adjust the dose if necessary.
  • Other medicines that stimulate red blood cell production: Combining these can cause your blood counts to rise too rapidly, increasing the risk of serious side effects.
     

Login/Sign Up

verifiedApollotooltip

No clinically significant food interactions are known with Cresp+100 PFS Injection 0.5 ml when used as directed.

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ERYTHROPOIESIS STIMULATING AGENTS (ESAs)]

FAQs

Cresp+100 PFS Injection 0.5 ml is used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). Cresp+100 PFS Injection 0.5 ml helps to reverse anaemia and reduce the need for blood transfusion.
It is suggested to store the Cresp+100 PFS Injection 0.5 ml in the refrigerator and protect it from light. However, a person should not freeze it.
It is advised to tell your doctor about your medical conditions like heart disease, high blood pressure, kidney disease, a stroke, heart attack, or blood clot, a seizure, a latex allergy to avoid any type of medical condition.
A person who is allergic to any chemical compound present in Cresp+100 PFS Injection 0.5 ml or have uncontrolled/untreated high blood pressure, or ever had pure red cell aplasia (a type of anaemia) caused by using darbepoetin alfa, or epoetin alfa is not allowed to take a name.
Consult your doctor before taking Cresp+100 PFS Injection 0.5 ml if you are pregnant or planning for pregnancy. Your doctor will prescribe Cresp+100 PFS Injection 0.5 ml only if the benefits outweigh the risks.
Cresp+100 PFS Injection 0.5 ml contains a protein "Darbepoetin alfa", which works by providing signals to the bone marrow to make more red blood cells. As in chronic kidney disease, the kidney gets damaged and doesn't filter the blood in the way it should be leading to anemia.
Cresp+100 PFS Injection 0.5 ml may cause side effects such as injection site pain, cough, low blood pressure, headache, diarrhoea, body pains, shortness of breath or stomach pain. If these side effects persist or worsen, please consult your doctor.
After beginning treatment with Cresp+100 PFS Injection 0.5 ml, it takes around 2 to 6 weeks for increase in haemoglobin level in blood.
Cresp+100 PFS Injection 0.5 ml is used only if anaemia is due to chronic (long term) kidney disease and chemotherapy for some types of cancer (except for bone marrow and blood cells).
Cresp+100 PFS Injection 0.5 ml may cause high blood pressure particularly in patients with long term kidney disease due to the rapid increase of red blood cells in the initial 3 months after starting Cresp+100 PFS Injection 0.5 ml.
Cresp+100 PFS Injection 0.5 ml is not used in the treatment of cancer. It is used in treatment of anemia (low levels of healthy red blood cells) in patients receiving chemotherapy for some types of cancer (except for bone marrow or blood cells cancer).
Cresp+100 PFS Injection 0.5 ml should be used with extreme caution as it can cause serious side effects and can even be life-threatening. The patient should follow doctor’s recommendations strictly.
If you have deficiencies of folic acid, vitamin B12 or iron, you may not respond to Cresp+100 PFS Injection 0.5 ml. It is important that you take measures to correct these deficiencies. Other reasons may be infections, bleeding, inflammation and bone marrow fibrosis. If you have any concerns, consult your doctor.
Cresp+100 PFS Injection 0.5 ml is usually not recommended for children as the safety and effectiveness were not established. However, if you have any concerns regarding the use of Cresp+100 PFS Injection 0.5 ml for children, please consult your doctor.
Yes, you can inject it at home once a healthcare provider has trained you on how to prepare and inject it safely. Do not attempt to self-inject until you are confident in the process. Talk to your doctor or pharmacist if you need a demonstration.
This injection prompts your body to build new red blood cells, which requires a large amount of iron. If your iron levels are low, the medicine will not work as effectively. Talk to your doctor or pharmacist about the right iron supplement for you.
If the injection has been frozen, do not use it, even if it has thawed out. Freezing destroys the active components of the medicine, making it unsafe and ineffective. Dispose of it safely and use a new syringe. Talk to your doctor or pharmacist if you need assistance with replacement.
Your doctor will likely order blood tests weekly or bi-weekly when you start treatment and then monthly once your red blood cell levels stabilise. These tests help ensure you are receiving the correct dose. Talk to your doctor about your blood test schedule.
A sudden, severe headache can be a warning sign of a dangerous rise in blood pressure. You should seek immediate medical help or contact your doctor right away if this occurs. Talk to your doctor about how to manage blood pressure spikes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). Darbamg071902Lb [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Darbepoetin Alfa Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Darbepoetin alfa. 2001. [Accessed on 23 Jan. 2019]Check here
  4. Darbepoetin alfa. 2001. [Accessed on 07 Apr. 2019]Check here
  5. Drugs and Lactation Database (LactMed®) [Internet]. 2006. [Accessed on 17 Jun. 2023]Check here
  6. John Powell and Cheryle Gurk-Turner. Darbepoetin alfa (Aranesp). NIH National Library of Medicine, National center for biotechnology information. PubMed Central. July 2002. [Accessed on 4th June 2022]Check here
  7. Amgen Technology (Ireland) Unlimited Company. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 4th June 2022] ,Check here

Country of origin

India

Manufacturer/Marketer address

8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, India.
Other Info - CRE0458

Buy best Hematopoietic System products by

whatsapp Floating Button
Buy Now
Add to Cart