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compositionComposition:FOSFOMYCIN-4000MG
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Critifos 4 gm Injection 1's is an antibiotic medicine, used in the treatment of bacterial infections of bones and joints, heart, lungs, central nervous system, stomach, blood, skin, and tissues below the skin, bacterial meningitis, complicated urinary tract infections. This medicine works by stopping the growth of bacteria and thereby helps reduce various bacterial infections. It will be administered by the doctor in hospital.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FOSFOMYCIN-4000MG

Manufacturer/Marketer :

Aequitas Healthcare Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Critifos 4 gm Injection 1's

Critifos 4 gm Injection 1's is a sterile, injectable antibiotic used to treat severe and complicated bacterial infections throughout the body. It is typically prescribed for deep-seated infections in the urinary tract, lungs, bones, and brain when other standard antibiotics may not be effective. This medicine helps eliminate harmful bacteria and stops the spread of infection.

This medicine is injected on a regular schedule determined by your doctor to keep a steady level of the drug in your body. Because it is given directly into a vein, you do not need to worry about taking it with or without food. Drinking plenty of water and getting extra rest during your treatment can help your body recover much faster.

While using Critifos 4 gm Injection 1's, you might experience mild side effects like headache, dizziness, or slight irritation at the injection site. However, you must contact your doctor immediately if you develop serious symptoms, such as severe watery diarrhoea, stomach cramps, or a sudden skin rash.

Before starting this treatment, tell your doctor if you have kidney problems, heart failure, or are on a low-salt diet, as this injection contains high amounts of sodium. Do not take this if you have ever had a severe allergic reaction to this medicine or its ingredients in the past.

Certain medications, such as water pills, can interact with this medicine by affecting how your kidneys remove it from your body. You should also consult your doctor before using Critifos 4 gm Injection 1's if you are pregnant, breastfeeding, or are an older adult, as your dosing may need special monitoring.

Uses of Critifos 4 gm Injection 1's

Critifos 4 gm Injection 1's is used to treat severe and complicated bacterial infections throughout the body. The detailed uses of Critifos 4 gm Injection 1's are as follows:

  • Severe Urinary Tract Infections: Helps clear deep-seated, complicated bacterial infections in the bladder or kidneys when standard oral antibiotics are not suitable.
  • Bone and Joint Infections (Osteomyelitis): Penetrates deep bone tissues to eliminate bacteria causing painful and destructive bone infections.
  • Severe Lower Respiratory Tract Infections: Targets and destroys bacteria in the lungs to treat severe, hospital-acquired pneumonia.
  • Bacterial Meningitis: Crosses into the brain and spinal fluid to fight dangerous, life-threatening meningeal infections.
  • Bloodstream Infections (Sepsis): Works rapidly through the blood circulation to stop widespread bacterial growth and protect vital organs.

Key Benefits

Critifos 4 gm Injection 1's provides fast and effective treatment for serious bacterial infections through intravenous administration. By delivering the medicine directly into the bloodstream, it rapidly targets infection-causing bacteria and offers an effective option for treating difficult-to-manage infections.

  • Rapid Action Against Severe Infections: Because this medicine is administered directly into a vein, it reaches the bloodstream immediately, helping it begin fighting serious bacterial infections without delay.
  • Effective Against Resistant Bacteria: This medicine works through a unique antibacterial mechanism, making it effective against certain drug-resistant bacteria when other antibiotics may not be suitable.
  • Supports Faster Recovery: By reducing the growth of infection-causing bacteria, this medicine helps relieve symptoms such as fever, pain, and inflammation while supporting the body's recovery from severe infections.

Directions for Use

  • Critifos 4 gm Injection 1's is administered only by qualified healthcare professionals, usually through intravenous infusion in a hospital or clinic setting.
  • This medication must not be self-administered, as it requires careful dosing, preparation, and monitoring.
  • It is important to complete the full course of treatment as prescribed, even if symptoms improve, to prevent recurrence or resistance.

How Critifos 4 gm Injection 1's Works

Critifos 4 gm Injection 1's contains a single active medicine, fosfomycin, that stops bacterial growth in a highly specific way. It works by blocking a key step in how bacteria build their protective outer walls. Without a strong, fully formed outer wall, the bacteria cannot survive, grow, or multiply in your body. Your immune system can then easily clear the remaining bacteria, leading to a complete recovery from the infection.
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Alcohol

Caution

The interaction of alcohol with Critifos 4 gm Injection 1's is unknown. Hence, avoid or limit alcohol consumption while on treatment with Critifos 4 gm Injection 1's.

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Pregnancy

Safe if prescribed

Critifos 4 gm Injection 1's is considered safe to be used in pregnancy. However, if you are pregnant, inform your doctor before receiving Critifos 4 gm Injection 1's. Your doctor prescribes this medicine if the benefits outweigh the risks.

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Breast Feeding

Safe if prescribed

Small amounts of Critifos 4 gm Injection 1's are excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Critifos 4 gm Injection 1's may cause weakness or confusion in some people. Therefore, avoid driving if you notice any of these symptoms after taking Critifos 4 gm Injection 1's.

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Liver

Caution

Please consult a doctor if you have a history of liver diseases/conditions.

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Kidney

Caution

Take Critifos 4 gm Injection 1's with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Critifos 4 gm Injection 1's may be used with caution in children if prescribed by a doctor, and the dose depends on the child’s age and weight.

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Heart

Consult your doctor

Please consult your doctor if you have any concerns regarding the usage of Critifos 4 gm Injection 1's in heart patients.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Critifos 4 gm Injection 1's to geriatric patients. Your doctor will prescribe Critifos 4 gm Injection 1's if the benefits outweigh the risks.

What if I have taken an overdose of Critifos 4 gm Injection 1's

In case of an accidental overdose, seek immediate medical attention or contact an emergency helpline. Signs of an overdose may include convulsions, hearing problems, or a persistent metallic taste in the mouth.

Diet & Lifestyle Advise

  • Stay Well-Hydrated: Drink plenty of water and clear fluids (unless advised otherwise by your doctor) to help your kidneys flush the medicine and infection waste products out of your body.
  • Monitor Sodium Intake: This injection contains a significant amount of sodium. Talk to your doctor about limiting dietary salt, especially if you have high blood pressure or heart problems.
  • Support Gut Health: Antibiotics can disrupt your natural gut flora. Consider eating probiotic-rich foods, like unsweetened yoghurt, a few hours after your injection to support healthy digestion.
  • Get Plenty of Rest: Ensure you get adequate sleep and avoid heavy physical exertion so your body can dedicate its energy to healing.
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How Soon It Starts Working

The time required for Critifos 4 gm Injection 1's to start to work: The onset time of Critifos 4 gm Injection 1's has not been clinically established. The time for which the effects of Critifos 4 gm Injection 1's last: The duration of Critifos 4 gm Injection 1's’s effect is clinically not established.

What if you forget to take Critifos 4 gm Injection 1's

Because this medicine is typically injected by a healthcare professional, a missed dose is unlikely. If you are managing your treatment at home and miss a scheduled dose, contact your doctor or nurse immediately for instructions. Do not inject a double dose to make up for a missed one.

Storage

•Store the dry powder vials of Critifos 4 gm Injection 1's at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Always inspect the liquid solution vial before use; do not inject it if you see any floating particles, cloudiness, or discolouration.
  • If you are injecting this medicine at home, rotate your injection sites daily to prevent vein irritation, soreness, or bruising.
  • Complete the entire course of treatment exactly as prescribed, even if your symptoms disappear. Stopping too early can cause the infection to return and make the bacteria resistant to future treatment.
  • Keep a close eye on your injection site and report any signs of localised infection, such as worsening redness, warmth, throbbing pain, or pus, to your healthcare provider.
  • Monitor your body for sudden swelling in your ankles, feet, or hands, which can occur due to the sodium content in this medicine.

verifiedApollotooltip

  • Water pills (loop diuretics): May alter how your kidneys process and clear this medicine from your system.
  • Other kidney-straining medicines: Combining this injection with other drugs that impact the kidneys may increase the risk of kidney strain.

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verifiedApollotooltip
  • There are no known direct interactions with food, as this medication is injected directly into a vein and bypasses the digestive tract.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Critifos 4 gm Injection 1's belongs to a class of drugs called antibiotics used in the treatment of bacterial infections. Critifos 4 gm Injection 1's is used to treat bacterial meningitis (infection of membranes protecting the brain and spinal cord), complicated urinary tract infections, bacterial infections of bones and joints, heart, lungs, central nervous system, stomach, blood, skin, and tissues below the skin.
Critifos 4 gm Injection 1's contains Fosfomycin, which inhibits the formation of the bacterial cell wall (a protective covering) necessary for survival. Thereby killing bacteria. Also, Critifos 4 gm Injection 1's decreases the attachment of bacteria to cells lining the urinary bladder.
Critifos 4 gm Injection 1's may cause taste disturbances as a temporary side effect. However, if the condition persists or worsens, please inform your doctor.
If you are undergoing dialysis or have kidney problems, inform your doctor before receiving Critifos 4 gm Injection 1's so that the dose may be adjusted.
Critifos 4 gm Injection 1's may cause diarrhoea as a rare side effect. However, if the condition persists or worsens with fever or severe stomach pain, please consult a doctor immediately, as these might be signs of large intestine infection.
You are not recommended to take blood thinner while receiving Critifos 4 gm Injection 1's as co-administration of these two medicines may alter the blood thinner's ability to prevent blood from clotting. However, please consult your doctor before taking other medicines while receiving Critifos 4 gm Injection 1's.
The side effects of Critifos 4 gm Injection 1's include injection site reactions, taste disturbances and gastrointestinal disturbances. If these side effects persist or worsen, please consult your doctor.
The dosing schedule is decided by your doctor and the dose depends on bacteria causing the infection, site and severity of the infection. Your doctor will consider your body weight, age, and status of kidney function while deciding the dose and duration.
As Critifos 4 gm Injection 1's is eliminated by the kidneys, the time for which Critifos 4 gm Injection 1's stays in the body depends upon how well kidney functions. In healthy adults, about 80-90% of the total medication injected is excreted by kidneys within 10 hours following a single injection into the veins. The medicine may remain for a longer time in the body if the patient has kidney dysfunction.
Critifos 4 gm Injection 1's is given as an injection or a slow drip (infusion) directly into a vein. This is typically done by a trained healthcare professional in a hospital or clinic. Talk to your doctor if you have questions about your administration schedule.
You should only inject this medicine at home if you have received complete, formal training from a healthcare provider on how to prepare the solution and perform the injection safely. Talk to your doctor to see if home administration is right for you.
Mild soreness or redness at the injection site is common. However, if you notice worsening redness, swelling, warmth, severe pain, or pus, contact your doctor or nurse right away, as these could be signs of a localised infection.
Sodium is part of the formulation that helps the dry antibiotic powder dissolve completely and safely into a sterile liquid solution for your veins. Talk to your doctor if you are on a restricted-salt diet.
It is highly recommended to avoid alcohol while being treated for a severe bacterial infection. Alcohol can dehydrate your body and interfere with your recovery process. Talk to your doctor for specific advice.
This medicine is only prescribed during pregnancy if the potential benefits outweigh the risks to the developing baby. If you are pregnant or planning to become pregnant, talk to your doctor before starting treatment.
No, this medicine is an antibiotic designed specifically to fight bacterial infections. It will not work against viral infections like colds, the flu, or COVID-19. Talk to your doctor for a proper diagnosis.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Unit No. 207, Neelkanth Commercial Centre, 122, Sahar Road, Andheri (East), Mumbai - 400099
Other Info - CRI0230
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