Cyclophil ME-25 Capsule 5's
MRP ₹149.5
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About Cyclophil ME-25 Capsule
Cyclophil ME-25 Capsule belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ rejection after a transplant. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.
Cyclophil ME-25 Capsule contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and lowers pain and inflammation in the joints.
Cyclophil ME-25 Capsule may cause side effects like headaches, vomiting, nausea, loss of appetite and diarrhoea. Most of these side effects do not require medical attention and resolve over time. However, consult your doctor if the side effects persist or worsen.
To treat your condition effectually, continue taking Cyclophil ME-25 Capsule for as long as your doctor has prescribed. Inform your doctor about your health condition and any medications you are taking to help rule out any potential/unpleasant side effects.
Uses of Cyclophil ME-25 Capsule
Cyclophil ME-25 Capsule is used to prevent organ rejection and treat psoriasis and rheumatoid arthritis. The detailed uses of Cyclophil ME-25 Capsule are as follows:
- Treatment of Organ Transplant Rejection: Cyclophil ME-25 Capsule is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants.
- Treatment of Psoriasis: Cyclophil ME-25 Capsule is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
- Treatment of Rheumatoid Arthritis: Cyclophil ME-25 Capsule is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.
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Directions for Use
- Cyclophil ME-25 Capsule can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Check the label for directions and use as advised by your doctor.
- Measure the prescribed dose of Cyclophil ME-25 Capsule using the dosing syringe. Mix it with apple or orange juice, stir well, and drink immediately.
- Do not store the prepared mixture for later use.
Key Benefits
- Cyclophil ME-25 Capsule suppresses the immune system to prevent the rejection of transplanted organs (e.g., kidney, liver, heart).
- It is also used in bone marrow and stem cell transplantation to prevent graft rejection.
- Cyclophil ME-25 Capsule helps control immune overactivity in various autoimmune conditions by blocking immune cells that attack the body’s own tissues.
- It reduces rapid skin cell growth and inflammation in severe psoriasis, leading to clearer skin and symptom relief.
- This medicine reduces joint pain, inflammation, and slows down joint damage in patients with active rheumatoid arthritis unresponsive to other therapies.
- It may also be used to treat severe atopic dermatitis, especially in patients who do not respond adequately to topical treatments.
- Helps manage severe inflammatory eye diseases that can threaten vision by reducing immune-mediated damage.
- It is used in certain cases of nephrotic syndrome (a kidney disorder causing excess protein loss in urine), especially when other treatments fail.
How Cyclophil ME-25 Capsule Works
Storage
- Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
- Avoid foods with label “partially hydrogenated oils”.
- Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
- Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
- Limit consumption of egg yolks.
- Exercise for at least 30 minutes 5 days a week.
- Aim for weight loss and maintain healthy weight.
- Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
- Limit alcohol consumption as excessive drinking may raise cholesterol levels.
- Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
- Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
- Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
- Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
- Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
- Monitor UTI symptoms and report any changes to your doctor.
- If antibiotics are prescribed, take them as directed and complete the full course.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Inform your doctor immediately if you experience a fever after starting a new medication.
- Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
- Monitor your body temperature to monitor fever progression.
- Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
- Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
- Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
- If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
- Limit processed foods and eat more vegetables and fruits.
- Exercise at least 30 minutes every day.
- Maintain a healthy weight.
- Quit smoking as it can worsen kidney damage.
- Control your blood pressure and blood glucose.
- Limit salt intake and alcohol consumption.
- Increased creatinine levels must be corrected immediately with the help of a doctor.
- Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
- Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
- Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
- Avoid smoking and drinking alcohol.
- Regular cleansing will help get rid of dead skin cells and stop ingrown hairs.
- Keep your hormones in balance by managing your stress, eating well and exercising regularly.
- Shaving, waxing, and bleaching are ways to get rid of extra hair.
What if I have taken an overdose of Cyclophil ME-25 Capsule
Drug Warnings
- Do not take Cyclophil ME-25 Capsule if you are allergic to any of the components.
- Let your doctor know before using Cyclophil ME-25 Capsule if you have/had liver or kidney problems, epilepsy, high blood pressure, low levels of magnesium, high levels of potassium, cancer, or infection.
- Cyclophil ME-25 Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
- Before taking Cyclophil ME-25 Capsule, inform your doctor if you have any type of cancer.
- Consult your doctor before taking Cyclophil ME-25 Capsule if you are pregnant or planning for pregnancy.
- Cyclophil ME-25 Capsule should not be taken by breastfeeding mothers as it passes into breast milk.
- Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.
How to manage the interaction:
Taking Cyclophil ME-25 Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Taking cyclosporine with cidofovir can increase the risk of kidney problems.
How to manage the interaction:
Taking Cyclophil ME-25 Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.
How to manage the interaction:
Taking Cyclophil ME-25 Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Combining Cyclophil ME-25 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Cyclophil ME-25 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Coadministration of pitavastatin with Cyclophil ME-25 Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Pitavastatin with Cyclophil ME-25 Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
Taking indinavir with ciclosporine may increase the blood levels and effects of Cyclophil ME-25 Capsule.
How to manage the interaction:
Co-administration of cyclosporine and indinavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, diarrhea, abdominal pain, dizziness, weakness, headache, shaking, fits, and increased or decreased urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Cyclophil ME-25 Capsule with ritonavir may significantly increases the blood levels of Cyclophil ME-25 Capsule.
How to manage the interaction:
Taking ritonavir with Cyclophil ME-25 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loose stools, abdominal pain, dizziness, weakness, headache, fits, shaking, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination, contact a doctor. Do not stop using any medications without talking to a doctor.
Coadministration of cisapride with cyclosporine may significantly increase the blood levels of cisapride which may increase the risk of an irregular heart rhythm.
How to manage the interaction:
There may be a possibility of interaction between cisapride and Cyclophil ME-25 Capsule, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
Using lercanidipine can make cyclosporine more effective at suppressing the immune system.
How to manage the interaction:
Co-administration of Cyclophil ME-25 Capsule with lercanidipine can possibly result in an interaction, but it can be taken if your doctor has advised it. Avoid taking cyclosporine along with other medications that suppress your immune system. It is important to watch out for any signs of infection and contact your doctor immediately if you experience symptoms such as serious infection, anemia, bleeding problems, paleness, fatigue, dizziness, bruising, fever, chills, diarrhea, sore throat, muscle aches, weight loss, or pain during urination. Do not stop using any medications without first talking to your doctor.
Using leflunomide together with Cyclophil ME-25 Capsule can increase the risk of side effects
How to manage the interaction:
Co-administration of Cyclophil ME-25 Capsule with leflunomide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience contact a doctor immediately if you experience symptoms such as serious infection, anemia, bleeding problems, paleness, fatigue, dizziness, bruising, fever, chills, diarrhea, sore throat, muscle aches, or pain during urination. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
- Consuming food rich in probiotics helps in developing the immune system against allergies.
- Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
- Avoid consumption of foods with excess sugar to prevent flare-up inflammation.
- Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
- Reducing stress and maintaining a regular sleep pattern would be helpful.
- Avoid getting in contact with harsh soaps, detergents, and rough fabrics.
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Alcohol
Safe if prescribed
You are recommended to avoid alcohol consumption while taking Cyclophil ME-25 Capsule. It could lead to increased dizziness.
Pregnancy
Consult your doctor
Cyclophil ME-25 Capsule belongs to pregnancy category C. Consult your doctor before taking Cyclophil ME-25 Capsule if you are pregnant or planning for pregnancy.
Breast Feeding
Consult your doctor
Cyclophil ME-25 Capsule passes into breast milk. Avoid breastfeeding while taking Cyclophil ME-25 Capsule.
Driving
Safe if prescribed
Cyclophil ME-25 Capsule may cause dizziness. Drive or operate machinery only if you are alert.
Liver
Consult your doctor
Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Consult your doctor
Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Safe if prescribed
Cyclophil ME-25 Capsule is not recommended for children as efficacy and safety have not been established.
Heart
Please inform your doctor if you have any pre-existing heart problems
Geriatrics
Consult your doctor
Cyclophil ME-25 Capsule should be given to elderly patients only if prescribed by a doctor. If you have any concerns, please consult your doctor.
FAQs
Cyclophil ME-25 Capsule is used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis.
Cyclophil ME-25 Capsule acts as an immunosuppressant, which helps in reducing inflammation and preventing joint stiffness, thereby providing relief from rheumatoid arthritis.
If you miss a dose of Cyclophil ME-25 Capsule, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose instead.
Diarrhoea might be a side effect of Cyclophil ME-25 Capsule. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Yes, the use of Cyclophil ME-25 Capsule may cause abnormal facial and body hair growth as a common side effect. Please consult your doctor if you have any concerns.
Cyclophil ME-25 Capsule is known to suppress the immune system. As a result, it increases the risk of infections and developing cancers, especially of the skin. Therefore, avoid prolonged exposure to sunlight by wearing suitable protective clothing and using sunscreen regularly.
Cyclophil ME-25 Capsule may cause high blood pressure. Therefore, consult the doctor before taking Cyclophil ME-25 Capsule if you have high blood pressure.
No, Cyclophil ME-25 Capsule is not a steroid. It is an immunosuppressant.
Cyclophil ME-25 Capsule may cause weight gain. Follow a healthy diet and exercise regularly to maintain proper weight. Consult your doctor if you have any concerns.
Cyclophil ME-25 Capsule may cause fatigue. Eat a healthy diet, get regular exercise, manage stress, improve sleep habits, and quit smoking. Doing these may help cope with fatigue.
Yes, your doctor will recommend certain tests to check your body’s response to Cyclophil ME-25 Capsule.
Cyclophil ME-25 Capsule may cause side effects like headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Talk to your doctor if you experience these side effects persistently.
Use the measuring cup/dosing syringe provided with the pack to measure the prescribed dose of Cyclophil ME-25 Capsule. Mix the solution/suspension in a glass of milk or orange juice, stir well, and consume immediately. Do not store the prepared mixture for later use.
You are advised to take Cyclophil ME-25 Capsule for the duration prescribed by the doctor. The duration of treatment will depend upon your condition and response to the treatment.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050715s035,050716s038lbl.pdf
- https://www.drugs.com/disease-interactions/cyclosporine.html
- https://www.medicines.org.uk/emc/files/pil.5300.pdf
- https://www.medicines.org.uk/emc/files/pil.1034.pdf
- https://www.webmd.com/drugs/2/drug-5645-9108/cyclosporine-oral/cyclosporine-oral/details
