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  3. Cyendiv 100Mg 60 Capsule

Cyendiv 100Mg 60 Capsule, Pack of 1 Capsule
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cyendiv 100Mg 60 Capsule is used to treat idiopathic pulmonary fibrosis (a disease that causes scarring of the lungs). It contains Nintedanib, which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. In some cases, this medicine may cause side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

NINTEDANIB-100MG

Manufacturer/Marketer :

Boehringer Ingelheim India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Cyendiv 100Mg 60 Capsule

Cyendiv 100Mg 60 Capsule is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, which makes it difficult to breathe deeply.

Cyendiv 100Mg 60 Capsule contains nintedanib, which helps reduce the scarring and swelling in the lungs by decreasing the release of naturally occurring growth factors in the body, allowing you to breathe better.

In some cases, you may experience common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to Cyendiv 100Mg 60 Capsule. Consult your doctor before taking Cyendiv 100Mg 60 Capsule if you are pregnant or breastfeeding. Cyendiv 100Mg 60 Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Consult your doctor if you are breastfeeding; your doctor will decide whether Cyendiv 100Mg 60 Capsule can be taken by breastfeeding mothers or not.

Uses of Cyendiv 100Mg 60 Capsule

Cyendiv 100Mg 60 Capsule is used in the treatment of Idiopathic pulmonary fibrosis. The detailed uses of Cyendiv 100Mg 60 Capsule are as follows: Treatment of Idiopathic pulmonary fibrosis

  • Idiopathic pulmonary fibrosis: Cyendiv 100Mg 60 Capsule aids in the breakdown and thinning of mucus in the airways, facilitating coughing and removal. It is especially beneficial in conditions like Idiopathic pulmonary fibrosis.

Directions for Use

  • Cyendiv 100Mg 60 Capsule should be taken with meals to enhance its effectiveness.
  • It is recommended to take Cyendiv 100Mg 60 Capsule twice daily or as advised by your doctor.
  • Swallow Cyendiv 100Mg 60 Capsule as a whole with a glass of water.
  • Do not crush, chew, or open it.

Medicinal Benefits

  • Cyendiv 100Mg 60 Capsule is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults.
  • Cyendiv 100Mg 60 Capsule can help effectively slow the rate of lung function decline by 50%.
  • Cyendiv 100Mg 60 Capsule helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better.
  • Cyendiv 100Mg 60 Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

How Cyendiv 100Mg 60 Capsule Works

Cyendiv 100Mg 60 Capsule contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Cyendiv 100Mg 60 Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

Storage

• Store in a cool and dry place away from sunlight.• Keep Cyendiv 100Mg 60 Capsule out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Cyendiv 100Mg 60 Capsule
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid other medicines that increase the risk of bleeding.
  • Use an electric razor and a soft-bristled toothbrush.
  • Monitor for signs of bleeding like bleeding gums, unusual bruising, blood in stool, nosebleeds, or heavy menstrual bleeding.
  • If you experience severe bleeding, apply direct pressure on the wound and consult a doctor promptly.
  • If the risk of bleeding is high, discuss with your doctor about possibility of switching to different medicine with a lower bleeding risk.

What if I have taken an overdose of Cyendiv 100Mg 60 Capsule

Take Cyendiv 100Mg 60 Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause serious adverse effects. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not use Cyendiv 100Mg 60 Capsule if you are allergic to any components present in Cyendiv 100Mg 60 Capsule.
  • Cyendiv 100Mg 60 Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Cyendiv 100Mg 60 Capsule.
  • Consult your doctor if you are breastfeeding; your doctor will decide whether the Cyendiv 100Mg 60 Capsule can be taken by breastfeeding mothers or not.
  • Keep your doctor informed about your health condition and medicines to rule out any side effects. 
  • Cyendiv 100Mg 60 Capsule may cause tiredness and dizziness, so drive with caution.
  • Avoid consuming alcohol with Cyendiv 100Mg 60 Capsule as it could lead to increased dizziness.
  • Cyendiv 100Mg 60 Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

verifiedApollotooltip
NintedanibRifampicin
Severe
NintedanibDexamethasone
Severe

Drug-Drug Interactions

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NintedanibRifampicin
Severe
How does the drug interact with Cyendiv 100Mg 60 Capsule:
Coadministration of Cyendiv 100Mg 60 Capsule with Rifampicin can decrease the blood levels of Cyendiv 100Mg 60 Capsule, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Cyendiv 100Mg 60 Capsule and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
NintedanibDexamethasone
Severe
How does the drug interact with Cyendiv 100Mg 60 Capsule:
Coadministration of Dexamethasone may lower the blood levels of Cyendiv 100Mg 60 Capsule, making the medication less effective in treating your condition.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Cyendiv 100Mg 60 Capsule if prescribed by the doctor. Contact a doctor if your symptoms do not improve. Do not discontinue any medications without consulting a doctor.
NintedanibPhenytoin
Severe
How does the drug interact with Cyendiv 100Mg 60 Capsule:
Coadministration of Phenytoin and Cyendiv 100Mg 60 Capsule may decrease the blood levels of Cyendiv 100Mg 60 Capsule, which may reduce Cyendiv 100Mg 60 Capsule's effectiveness.

How to manage the interaction:
Although taking Phenytoin and Cyendiv 100Mg 60 Capsule together can result in an interaction, it can be taken when your doctor has prescribed it. Contact a doctor if your symptoms do not improve. Do not stop taking any drugs without consulting a doctor.
NintedanibRifapentine
Severe
How does the drug interact with Cyendiv 100Mg 60 Capsule:
Coadministration of Cyendiv 100Mg 60 Capsule and Rifapentine can reduce the blood levels of Cyendiv 100Mg 60 Capsule.

How to manage the interaction:
There may be a possibility of interaction between Cyendiv 100Mg 60 Capsule and Rifapentine, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
NintedanibPhenobarbital
Severe
How does the drug interact with Cyendiv 100Mg 60 Capsule:
Taking Phenobarbital and Cyendiv 100Mg 60 Capsule can drastically lower Cyendiv 100Mg 60 Capsule levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Cyendiv 100Mg 60 Capsule can lead to interaction, they can be taken if recommended by a doctor. Contact a doctor if your symptoms do not improve. Do not stop using any medications without talking to a doctor.
NintedanibCarbamazepine
Severe
How does the drug interact with Cyendiv 100Mg 60 Capsule:
Coadministration of Cyendiv 100Mg 60 Capsule with Carbamazepine can reduce the levels and effects of Cyendiv 100Mg 60 Capsule.

How to manage the interaction:
Although taking carbamazepine and Cyendiv 100Mg 60 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not stop using any medications without first talking to your doctor.
NintedanibLeflunomide
Severe
How does the drug interact with Cyendiv 100Mg 60 Capsule:
Co-administration of Leflunomide and Cyendiv 100Mg 60 Capsule can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Cyendiv 100Mg 60 Capsule can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NintedanibTipranavir
Severe
How does the drug interact with Cyendiv 100Mg 60 Capsule:
Coadministration of Cyendiv 100Mg 60 Capsule and Tipranavir can reduce the blood levels of Cyendiv 100Mg 60 Capsule.

How to manage the interaction:
There may be a possibility of interaction between Cyendiv 100Mg 60 Capsule and Tipranavir, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without first consulting your doctor.
NintedanibTeriflunomide
Severe
How does the drug interact with Cyendiv 100Mg 60 Capsule:
Coadministration of Teriflunomide and Cyendiv 100Mg 60 Capsule can increase the risk of liver problems.

How to manage the interaction:
Coadministration of Teriflunomide and Cyendiv 100Mg 60 Capsule can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, loss of appetite, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately.
NintedanibFosphenytoin
Severe
How does the drug interact with Cyendiv 100Mg 60 Capsule:
Coadministration of Cyendiv 100Mg 60 Capsule with Fosphenytoin can reduce the levels of Cyendiv 100Mg 60 Capsule. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Cyendiv 100Mg 60 Capsule and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Cyendiv 100Mg 60 Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not known if alcohol interacts with Cyendiv 100Mg 60 Capsule. However, as a precautionary measure, you are recommended not to consume alcohol with the Cyendiv 100Mg 60 Capsule to avoid unpleasant side effects.

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Pregnancy

Unsafe

Cyendiv 100Mg 60 Capsule is listed as pregnancy category D. Because Cyendiv 100Mg 60 Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Cyendiv 100Mg 60 Capsule.

bannner image

Breast Feeding

Consult your doctor

Consult your doctor if you are breastfeeding; your doctor will decide whether Cyendiv 100Mg 60 Capsule can be taken by breastfeeding mothers or not.

bannner image

Driving

Unsafe

Cyendiv 100Mg 60 Capsule may significantly influence your ability to drive and use machines. You should not drive or operate machinery if you feel sick.

bannner image

Liver

Consult your doctor

Dose adjustment may be needed. Cyendiv 100Mg 60 Capsule is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns.

bannner image

Kidney

Consult your doctor

Dose adjustment may be needed. Cyendiv 100Mg 60 Capsule is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns.

bannner image

Children

Unsafe

Cyendiv 100Mg 60 Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

Have a query?

FAQs

Cyendiv 100Mg 60 Capsule is used to treat idiopathic pulmonary fibrosis (IPF), a disease marked by a progressive decline in lung function.

Cyendiv 100Mg 60 Capsule helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helping you breathe better.

Avoid smoking before starting the treatment while taking Cyendiv 100Mg 60 Capsule as smoking might alter the effectiveness of Cyendiv 100Mg 60 Capsule.

Cyendiv 100Mg 60 Capsule should be stopped when a person faces a serious side effect that affects life quality. Otherwise, it would be best to keep taking Cyendiv 100Mg 60 Capsule until your doctor asks you to stop it.

If you have any surgery, including dental surgery, please inform your doctor if you are taking Cyendiv 100Mg 60 Capsule as your doctor might stop Cyendiv 100Mg 60 Capsule before undergoing surgery.

In elderly patients, the risk of side effects is higher if you are taking Cyendiv 100Mg 60 Capsule. For the patients who are elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.

It is not recommended to discontinue the Cyendiv 100Mg 60 Capsule without consulting your healthcare provider. Abruptly stopping the medication can lead to disease progression or other complications. Consult your healthcare provider for personalised guidance if you have concerns or experience side effects.

If you forget to take a dose of Cyendiv 100Mg 60 Capsule, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for the missed one, as this can increase the risk of side effects.

Common side effects of Cyendiv 100Mg 60 Capsule may include nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity in some individuals. Most of these side effects do not require medical attention and will resolve gradually over time. However, if you experience these side effects persistently, inform your doctor.

Cyendiv 100Mg 60 Capsule is not recommended for use in patients with severe liver impairment. Please consult your doctor if you have a liver impairment or any concerns before Cyendiv 100Mg 60 Capsule.

Country of origin

Germany

Manufacturer/Marketer address

1102, Hallmark Business Plaza, 11th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
Other Info - CYE0001

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 12, 2025 | 4:43 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.nhs.uk/conditions/idiopathic-pulmonary-fibrosis/treatment/
  2. https://www.medicines.org.uk/emc/product/1786/smpc#gref
  3. https://www.medicines.org.uk/emc/files/pil.1786.pdf

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