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Composition

CYTARABINE-100MG

Manufacturer/Marketer

Fresenius Kabi India Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Cytarine 100 mg Injection 1 ml

Cytarine 100 mg Injection 1 ml is an anticancer medicine used in the treatment of leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. Cytarine 100 mg Injection 1 ml is used in the treatment of different types of leukemias, such as acute non-lymphocytic leukemia, acute lymphocytic leukemia, chronic myelocytic leukemia and meningeal leukemia.

Cytarine 100 mg Injection 1 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, Cytarine 100 mg Injection 1 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Cytarine 100 mg Injection 1 ml may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dark-coloured urine, stomach pain, hair loss, dizziness, weakness, and pain at the site of injection, prescribed by your doctor. Most of these side effects of Cytarine 100 mg Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer Cytarine 100 mg Injection 1 ml. Hence, do not self-administer.

If you are allergic to Cytarine 100 mg Injection 1 ml, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Cytarine 100 mg Injection 1 ml. Cytarine 100 mg Injection 1 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had kidney or liver disease. Avoid alcohol consumption with Cytarine 100 mg Injection 1 ml as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Cytarine 100 mg Injection 1 ml may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out.

Uses of Cytarine 100 mg Injection 1 ml

Treatment of Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia

Medicinal Benefits

Cytarine 100 mg Injection 1 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for cell growth, repair and multiplication. Thus, Cytarine 100 mg Injection 1 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Side Effects of Cytarine 100 mg Injection 1 ml

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dark-coloured urine
  • Dizziness
  • Confusion
  • Stomach pain
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

Directions for Use

Your oncology doctor will administer Cytarine 100 mg Injection 1 ml. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Cytarine 100 mg Injection 1 ml should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Cytarine 100 mg Injection 1 ml. Cytarine 100 mg Injection 1 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had any pre-existing liver or kidney disease. Avoid taking Cytarine 100 mg Injection 1 ml if you are pregnant, as it may harm the foetus. Avoid alcohol consumption with Cytarine 100 mg Injection 1 ml as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Cytarine 100 mg Injection 1 ml may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Cytarine 100 mg Injection 1 ml as it may cause infection.

Therapeutic Class

ANTINEOPLASTIC

Drug Interactions

Drug-Drug Interactions: Cytarine 100 mg Injection 1 ml may interact with medicines used to treat ulcerative colitis (mesalazine, olsalazine), anti-inflammatory drugs (sulfasalazine), aminoglycosides (gentamicin, amikacin, neomycin), cardiac glycoside, cholera vaccine, typhoid vaccine.

Drug-Food Interactions: Cytarine 100 mg Injection 1 ml may interact with alcohol. Therefore, avoid alcohol consumption with Cytarine 100 mg Injection 1 ml as it may increase the risk of liver damage.

Drug-Disease Interactions: Inform your doctor if you have liver or kidney disease before starting treatment with Cytarine 100 mg Injection 1 ml.

Drug-Drug Interactions Checker List

  • MESALAZINE
  • OLSALAZINE
  • SULFASALAZINE
  • GENTAMICIN
  • AMIKACIN
  • CHOLERA VACCINE
  • TYPHOID VACCINE

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Cytarine 100 mg Injection 1 ml as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Habit Forming

No

What if I have taken an overdose of Cytarine 100 mg Injection 1 ml

Since Cytarine 100 mg Injection 1 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Cytarine 100 mg Injection 1 ml may cause confusion, mental/mood changes.

Special Advise

  • Regular blood tests are recommended while taking Cytarine 100 mg Injection 1 ml to monitor the number and type of cells in the blood. 
  • Cytarine 100 mg Injection 1 ml, like other cytotoxic medicines, can cause hyperuricemia due to the fast lysis of neoplastic cells. Blood uric acid levels should be monitored and be ready to utilize any supportive or pharmacologic interventions that may be required to address this condition.

Disease/Condition Glossary

Chronic myeloid leukemia: It is a type of cancer that occurs in the bone marrow and blood. It abnormally increases the number of immature white blood cells. The symptoms include unexplained weight loss, excessive sweating, bone pain, frequent nosebleeds, heavier-than-normal periods in females, and shortness of breath. The risk factors include smoking and genetic or blood disorders.

Acute lymphocytic leukemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.

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Alcohol

Unsafe

Avoid consumption of alcohol with Cytarine 100 mg Injection 1 ml as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Cytarine 100 mg Injection 1 ml. You should not become pregnant while on treatment with Cytarine 100 mg Injection 1 ml.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving Cytarine 100 mg Injection 1 ml. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Cytarine 100 mg Injection 1 ml causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving Cytarine 100 mg Injection 1 ml.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Cytarine 100 mg Injection 1 ml. It may lead to CNS toxicity in high doses.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Cytarine 100 mg Injection 1 ml as it may lead to kidney failure. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Cytarine 100 mg Injection 1 ml, combined with other approved anti-cancer medications, is suggested for inducing remission in adults and children with acute non-lymphocytic leukemia. Consult your doctor for more information.

Country of origin

India

Manufacturer/Marketer address

Fresenius Kabi AG? , Else-Kr?ner-Stra?e 1 ? , 61352 Bad Homburg , Germany
Other Info - CYT0087

FAQs

Cytarine 100 mg Injection 1 ml is used to treat Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia.
Cytarine 100 mg Injection 1 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair.
If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Cytarine 100 mg Injection 1 ml as it may cause infections.
Cytarine 100 mg Injection 1 ml may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Cytarine 100 mg Injection 1 ml if you are planning to become pregnant.
Cytarine 100 mg Injection 1 ml contains cytarabine as its active component. It is an anticancer medicine which belongs to the class of anti-metabolites.
Cytarine 100 mg Injection 1 ml is not considered a vesicant (irritant), but it should be administered carefully to prevent any potential issues.
No, ototoxicity (hearing damage) has not been reported with Cytarine 100 mg Injection 1 ml use. However, if you experience any related symptoms, it is important to consult your doctor.
Yes, Cytarine 100 mg Injection 1 ml is a cytotoxic (cell-damaging).
Yes, Cytarine 100 mg Injection 1 ml may cause hair loss as this is one of its side effects. However, please, consult a doctor if this persists for longer durations.
Cytarine 100 mg Injection 1 ml causes side effects such as nausea, vomiting, mouth ulcers, loss of appetite, diarrhoea, dark-coloured urine, confusion, dizziness, stomach pain, weakness, and injection site reactions. These will gradually reduce over time. However, consult a doctor if any of these persists longer.

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