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ORAL

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Not Returnable

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About Dabitor 150 Capsule 10's

Dabitor 150 Capsule 10's is used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. It is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung).

Dabitor 150 Capsule 10's contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots.

You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

If you are known to be allergic to Dabitor 150 Capsule 10's or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabitor 150 Capsule 10's. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabitor 150 Capsule 10's.

Uses of Dabitor 150 Capsule 10's

Dabitor 150 Capsule 10's is used in the prevention of blood clot formation, deep vein thrombosis, and pulmonary embolism. The detailed uses of Dabitor 150 Capsule 10's are as follows:

  • Stroke Prevention: Dabitor 150 Capsule 10's is used especially in patients with non-valvular atrial fibrillation.
  • Deep Vein Thrombosis (DVT): Dabitor 150 Capsule 10's treats and prevents clots in the legs.
  • Pulmonary Embolism (PE): Dabitor 150 Capsule 10's prevents clots from traveling to the lungs.
  • Post-Surgical Clot Prevention: Dabitor 150 Capsule 10's is used in clot prevention after hip or knee replacement surgery.
  • Recurrent Clot Prevention: Dabitor 150 Capsule 10's reduces risk of DVT/PE recurrence.

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Directions for Use

  • Dabitor 150 Capsule 10's can be taken with or without food.
  • It is usually taken twice daily, or as prescribed by your doctor.
  • Swallow the whole Dabitor 150 Capsule 10's with a glass of water.
  • Do not break, chew, or open it.

Medicinal Benefits

  • Dabitor 150 Capsule 10's is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation.
  • It makes the blood flow easily through the veins, making it less likely to form a serious blood clot. Thus, Dabitor 150 Capsule 10's helps prevent blood clots, thereby reducing the risk of heart attack/stroke.
  • It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Dabitor 150 Capsule 10's works by stopping the action of the clotting factor (thrombin).
  • Dabitor 150 Capsule 10's prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots.
  • Reduces the risk of stroke in persons with atrial fibrillation (irregular heartbeat).

How Dabitor 150 Capsule 10's Works

Dabitor 150 Capsule 10's contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (a soluble protein) to fibrin (an insoluble protein), thereby preventing blood clots. It facilitates the smooth flow of blood through the veins, reducing the likelihood of forming a serious blood clot. Thus, Dabitor 150 Capsule 10's helps prevent blood clots, thereby reducing the risk of heart attacks and strokes.

Storage

• Store in a cool and dry place away from sunlight. • Keep Dabitor 150 Capsule 10's out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Dabitor 150 Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid other medicines that increase the risk of bleeding.
  • Use an electric razor and a soft-bristled toothbrush.
  • Monitor for signs of bleeding like bleeding gums, unusual bruising, blood in stool, nosebleeds, or heavy menstrual bleeding.
  • If you experience severe bleeding, apply direct pressure on the wound and consult a doctor promptly.
  • If the risk of bleeding is high, discuss with your doctor about possibility of switching to different medicine with a lower bleeding risk.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Dabitor 150 Capsule 10's

Please do not exceed the recommended dose, as it might cause serious side effects. Signs and symptoms of an overdose of Dabitor 150 Capsule 10's may include an increased risk of bleeding. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are known to be allergic to Dabitor 150 Capsule 10's or any other medicines, please tell your doctor.
  • Do not stop taking this medicine on your own. Discontinuing Dabitor 150 Capsule 10's may worsen your condition and increase the risk of heart attack and stroke.
  • Dabitor 150 Capsule 10's is not recommended for children less than 18 years of age, as the Safety and effectiveness have not been established.
  • If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabitor 150 Capsule 10's.
  • Avoid consumption of alcohol while taking Dabitor 150 Capsule 10's as it may increase the risk of stomach bleeding.
  • If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabitor 150 Capsule 10's.
  • You should inform the doctor that you are taking Dabitor 150 Capsule 10's if you are due to undergo surgery.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dabitor 150 Capsule:
When Mifepristone is taken with Dabitor 150 Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Dabitor 150 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dabitor 150 Capsule:
Taking Dabitor 150 Capsule with Ramucirumab can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabitor 150 Capsule with Ramucirumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabitor 150 Capsule:
Combining Dabitor 150 Capsule with Deferasirox can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Dabitor 150 Capsule with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabitor 150 Capsule:
Taking Dabitor 150 Capsule with Eptifibatide can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabitor 150 Capsule with Eptifibatide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabitor 150 Capsule:
Using dabigatran together with ketorolac may increase the risk of bleeding.

How to manage the interaction:
Although taking Ketorolac and Dabitor 150 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor.
How does the drug interact with Dabitor 150 Capsule:
Taking Dabitor 150 Capsule with carbamazepine may significantly reduce the blood levels of dabigatran, which may make the medication less effective.

How to manage the interaction:
Although taking carbamazepine and Dabitor 150 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Dabitor 150 Capsule:
Phenobarbital can drastically lower Dabitor 150 Capsule blood levels, making the medicine less effective in treating and preventing blood clots.

How to manage the interaction:
Although taking phenobarbital with Dabitor 150 Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dabitor 150 Capsule:
Taking Dabitor 150 Capsule with Acalabrutinib can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabitor 150 Capsule with Acalabrutinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabitor 150 Capsule:
Taking Dabitor 150 Capsule with Urokinase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabitor 150 Capsule with Urokinase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabitor 150 Capsule:
Taking Dabitor 150 Capsule with Ticlopidine can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabitor 150 Capsule with Ticlopidine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DABIGATRAN ETEXILATE-150MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE-150MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Dabitor 150 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Dabitor 150 Capsule treatment.

Diet & Lifestyle Advise

  • Maintain healthy cholesterol and triglyceride levels.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Monitor your weight and exercise regularly to maintain a healthy heart.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Dabitor 150 Capsule 10's as it may increase the risk of bleeding.

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Pregnancy

Consult your doctor

Please consult your doctor if you are planning to become pregnant or are already pregnant before starting Dabitor 150 Capsule 10's. Your doctor will prescribe Dabitor 150 Capsule 10's only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Dabitor 150 Capsule 10's. Consult your doctor if you have any concerns.

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Driving

Consult your doctor

Dabitor 150 Capsule 10's usually does not affect your ability to drive or operate machinery. Consult your doctor if you have any concerns.

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Liver

Caution

Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dabitor 150 Capsule 10's. However, it is not recommended for patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Dabitor 150 Capsule 10's. However, it is not recommended for patients with severe kidney diseases.

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Children

Unsafe

Dabitor 150 Capsule 10's is not recommended for children below the age of 18 years, as the safety and efficacy of Dabitor 150 Capsule 10's have not been established in children.

FAQs

Dabitor 150 Capsule 10's is used to prevent blood clot formation, deep vein thrombosis (blood clots in deep veins), and pulmonary embolism (blood clots in the lungs).

Dabitor 150 Capsule 10's is a thrombin inhibitor. The inhibition of thrombin reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.

Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Dabitor 150 Capsule 10's a few days before surgery since it can cause an increased risk of bleeding during surgery.

Taking Dabitor 150 Capsule 10's during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Dabitor 150 Capsule 10's.

Dabitor 150 Capsule 10's may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.

No, you are not recommended to stop taking Dabitor 150 Capsule 10's without consulting your doctor as it may worsen the condition. Therefore, take Dabitor 150 Capsule 10's for as long as your doctor has prescribed it.

Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.

You can take Dabitor 150 Capsule 10's with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.

Take Dabitor 150 Capsule 10's as prescribed by your doctor. Depending on your medical conditions, you are advised to take Dabitor 150 Capsule 10's as long as your doctor has prescribed it for you.

You are recommended to avoid consumption of alcohol with Dabitor 150 Capsule 10's as it may increase the risk of bleeding.

Hair loss is not a known side effect of Dabitor 150 Capsule 10's. However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor will guide you on how to cope with this situation.

It varies from person to person and depends on the conditions that we treat.

Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dabitor 150 Capsule 10's. However, it is not recommended in patients with severe liver diseases.

Store in a cool and dry place away from sunlight. Keep Dabitor 150 Capsule 10's out of the sight and reach of children.

Yes, bleeding is the main risk associated with Dabitor 150 Capsule 10's treatment; patients should be monitored for signs of bleeding.

Dabitor 150 Capsule 10's is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Dabitor 150 Capsule 10's.

Common side effects of Dabitor 150 Capsule 10's may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Country of origin

India

Manufacturer/Marketer address

4-6, Bora Bazar St, Borabazar Precinct, Ballard Estate, Fort, Mumbai, Maharashtra 400001
Other Info - DAB0575

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