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  3. Dabixxa-110 Capsule 10's

Dabixxa-110 Capsule 10's, Pack of 10 CapsuleS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dabixxa-110 Capsule is an anticoagulant medicine used to prevent blood clot formation. This medicine prevents/treat conditions like deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), heart attack, and stroke. This medicine works by inhibiting the production of clotting factor Xa, also called thrombin. thereby preventing the conversion of fibrinogen to fibrin, a protein that helps prevent blood clot formation. Common side effects include bleeding, anaemia, nausea, stomach pain, and vomiting.
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Composition :

DABIGATRAN ETEXILATE-110MG

Manufacturer/Marketer :

Precia Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dabixxa-110 Capsule

Dabixxa-110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), and to reduce the risk of clots in people who have undergone knee or hip replacement surgeries. 

Dabixxa-110 Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Dabixxa-110 Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Take Dabixxa-110 Capsule as prescribed by your doctor. You are advised to take Dabixxa-110 Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects of Dabixxa-110 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Dabixxa-110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabixxa-110 Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabixxa-110 Capsule . Try not to stop taking this medicine on your own. Discontinuing Dabixxa-110 Capsule may worsen your condition and increase the risk of heart attack, and stroke.

Uses of Dabixxa-110 Capsule

Prevention of blood clot formation, deep vein thrombosis, and pulmonary embolism

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Medicinal Benefits

Dabixxa-110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Dabixxa-110 Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Dabixxa-110 Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

How Dabixxa-110 Capsule Works

Dabixxa-110 Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Dabixxa-110 Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dabixxa-110 Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • You can take your medicine with meals to lower the chances of getting stomach pain.
  • Avoid foods that are acidic, spicy, sugary, or greasy.
  • Eat foods that are easily digestible such as rice, toast, and bananas.
  • Eat your meals in smaller amounts throughout the day to prevent strain on your stomach and digestion.
  • Drink water or fluids to stay hydrated and prevent stomach upset.
  • Use a heating pad or massage your stomach area.
  • Engage in mild physical activities such as yoga and walking.

What if I have taken an overdose of Dabixxa-110 Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Dabixxa-110 Capsule may include an increase in the risk of bleeding. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are known to be allergic to Dabixxa-110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabixxa-110 Capsule . Dabixxa-110 Capsule is not recommended for children less than 18 years of age as the Safety and effectiveness have not been established. If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabixxa-110 Capsule . You should inform the doctor that you are taking Dabixxa-110 Capsule if you are due to undergo surgery. Avoid consumption of alcohol while taking Dabixxa-110 Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilatePhenobarbital
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Dabixxa-110 Capsule:
When Mifepristone is taken with Dabixxa-110 Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Dabixxa-110 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilatePhenobarbital
Severe
How does the drug interact with Dabixxa-110 Capsule:
Phenobarbital can drastically lower Dabixxa-110 Capsule blood levels, making the medicine less effective in treating and preventing blood clots.

How to manage the interaction:
Although taking phenobarbital with Dabixxa-110 Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateFenoprofen
Severe
How does the drug interact with Dabixxa-110 Capsule:
Taking Dabixxa-110 Capsule with Fenoprofen can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabixxa-110 Capsule with Fenoprofen together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateFosphenytoin
Severe
How does the drug interact with Dabixxa-110 Capsule:
When Dabixxa-110 Capsule is taken with Fosphenytoin, it can lower the rate at which the body breaks down Dabixxa-110 Capsule. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Fosphenytoin with Dabixxa-110 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms like sudden breathlessness, sharp chest pain, throbbing, cramping pain, swelling, redness or warmth in legs or arms, it's important to let your doctor know right away. They can recommend other options that won't cause any problems with your current medications. Do not discontinue any medications without first consulting your doctor.
Dabigatran etexilateReteplase
Severe
How does the drug interact with Dabixxa-110 Capsule:
Taking Dabixxa-110 Capsule with Reteplase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabixxa-110 Capsule with Reteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateTinzaparin
Severe
How does the drug interact with Dabixxa-110 Capsule:
Taking Dabixxa-110 Capsule with Tinzaparin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabixxa-110 Capsule with Tinzaparin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateTicagrelor
Severe
How does the drug interact with Dabixxa-110 Capsule:
Taking ticagrelor with Dabixxa-110 Capsule may increase the risk of bleeding.

How to manage the interaction:
Although taking Dabixxa-110 Capsule with Ticagrelor together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact your doctor immediately. Do not stop using any medications without consulting your doctor.
Dabigatran etexilateCarbamazepine
Severe
How does the drug interact with Dabixxa-110 Capsule:
Taking Dabixxa-110 Capsule with carbamazepine may significantly reduce the blood levels of dabigatran, which may make the medication less effective.

How to manage the interaction:
Although taking carbamazepine and Dabixxa-110 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Dabigatran etexilatePhenytoin
Severe
How does the drug interact with Dabixxa-110 Capsule:
Coadministration of Phenytoin and Dabixxa-110 Capsule may decrease the blood levels of Dabixxa-110 Capsule, which may make Dabixxa-110 Capsule less effective.

How to manage the interaction:
Although taking Phenytoin and Dabixxa-110 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
Dabigatran etexilateVerapamil
Severe
How does the drug interact with Dabixxa-110 Capsule:
Taking Verapamil with Dabixxa-110 Capsule may increase the blood levels and effects of dabigatran. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Dabixxa-110 Capsule and Verapamil together may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience paleness of skin, fatigue, dizziness, fainting, unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, or weakness. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Dabixxa-110 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Dabixxa-110 Capsule treatment.

Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Dabixxa-110 Capsule Substitute

Substitutes safety advice

  • Pradaxa 110 mg Capsule 10's

    by Others

    ₹32.04per tablet

  • Dabiclot 110 Capsule 10's

    by AYUR

    ₹30.47per tablet

  • Dabigat 110 Capsule 10's

    by AYUR

    ₹29.34per tablet

  • Goodflo 110 Capsule 10's

    by AYUR

    ₹28.71per tablet

  • Dabilong 110 mg Capsule 10's

    by AYUR

    ₹32.04per tablet

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Dabixxa-110 Capsule as it may increase the risk of bleeding.

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Pregnancy

Caution

Please consult your doctor if you are planning to become pregnant or already pregnant before starting Dabixxa-110 Capsule . Your doctor will prescribe Dabixxa-110 Capsule only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Dabixxa-110 Capsule . Consult your doctor if you have nay concerns.

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Driving

Safe if prescribed

Dabixxa-110 Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dabixxa-110 Capsule . However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Dabixxa-110 Capsule . However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Dabixxa-110 Capsule is not recommended for children below the age of 18 years as the safety and efficacy of Dabixxa-110 Capsule have not been established in children.

FAQs

Dabixxa-110 Capsule is used to prevent blood clot formation, deep vein thrombosis (blood clots in deep veins), and pulmonary embolism (blood clots in the lungs).

Dabixxa-110 Capsule is a thrombin inhibitor. The inhibition of thrombin, reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.

Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Dabixxa-110 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Taking Dabixxa-110 Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Dabixxa-110 Capsule .

Dabixxa-110 Capsule may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.

No, you are not recommended to stop taking Dabixxa-110 Capsule without consulting your doctor as it may worsen the condition. Therefore, take Dabixxa-110 Capsule for as long as your doctor has prescribed it.

Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.

You can take Dabixxa-110 Capsule with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.

Take Dabixxa-110 Capsule as prescribed by your doctor. Depending on your medical conditions, you are advised to take Dabixxa-110 Capsule as long as your doctor has prescribed it for you.

You are recommended to avoid consumption of alcohol with Dabixxa-110 Capsule as it may increase the risk of bleeding.

Hair loss is not a known side effect of Dabixxa-110 Capsule . However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor guide you on how to cope with this situation.

It varies from person to person and depends on the conditions that we treat.

Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dabixxa-110 Capsule . However, it is not recommended in patients with severe liver diseases.

Store in a cool and dry place away from sunlight. Keep Dabixxa-110 Capsule out of the sight and reach of children.

Yes, bleeding is the main risk associated with Dabixxa-110 Capsule treatment; patients should be monitored for signs of bleeding.

Dabixxa-110 Capsule is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Dabixxa-110 Capsule .

Common side effects of Dabixxa-110 Capsule may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Country of origin

India

Manufacturer/Marketer address

D-502, Laxmi Narayan, Thane (W), Thane - 400610, Maharashtra India
Other Info - DAB0425

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Author Details

Doctor imageDoctor badge

Written By

Veda Maddala

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:46 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/mtm/dabigatran.html
  2. https://www.nhs.uk/medicines/dabigatran/
  3. https://www.medicines.org.uk/emc/files/pil.6229.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022512s007lbl.pdf
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