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  3. Dabixxa-110 Capsule 10's

Dabixxa-110 Capsule 10's, Pack of 10 CapsuleS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dabixxa-110 Capsule is an anticoagulant medicine used to prevent blood clot formation. This medicine prevents/treat conditions like deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), heart attack, and stroke. This medicine works by inhibiting the production of clotting factor Xa, also called thrombin. thereby preventing the conversion of fibrinogen to fibrin, a protein that helps prevent blood clot formation. Common side effects include bleeding, anaemia, nausea, stomach pain, and vomiting.
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Composition :

DABIGATRAN ETEXILATE-110MG

Manufacturer/Marketer :

Precia Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dabixxa-110 Capsule

Dabixxa-110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), and to reduce the risk of clots in people who have undergone knee or hip replacement surgeries. 

Dabixxa-110 Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Dabixxa-110 Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Take Dabixxa-110 Capsule as prescribed by your doctor. You are advised to take Dabixxa-110 Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects of Dabixxa-110 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Dabixxa-110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabixxa-110 Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabixxa-110 Capsule . Try not to stop taking this medicine on your own. Discontinuing Dabixxa-110 Capsule may worsen your condition and increase the risk of heart attack, and stroke.

Uses of Dabixxa-110 Capsule

Dabixxa-110 Capsule is used in the prevention of blood clot formation, deep vein thrombosis, and pulmonary embolism. The detailed uses of Dabixxa-110 Capsule are as follows:<br/>• Stroke Prevention: Dabixxa-110 Capsule is used especially in patients with non-valvular atrial fibrillation.<br/>• Deep Vein Thrombosis (DVT): Dabixxa-110 Capsule treats and prevents clots in the legs.<br/>• Pulmonary Embolism (PE): Dabixxa-110 Capsule prevents clots from traveling to the lungs.<br/>• Post-Surgical Clot Prevention: Dabixxa-110 Capsule is used in clot prevention after hip or knee replacement surgery.<br/>• Recurrent Clot Prevention: Dabixxa-110 Capsule reduces risk of DVT/PE recurrence.<br/>

Have a query?

Directions for Use

• Dabixxa-110 Capsule can be taken with or without food.• It is usually taken twice daily, or as prescribed by your doctor.• Swallow the whole Dabixxa-110 Capsule with a glass of water.• Do not break, chew, or open it.

Medicinal Benefits

Dabixxa-110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Dabixxa-110 Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Dabixxa-110 Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

How Dabixxa-110 Capsule Works

Dabixxa-110 Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Dabixxa-110 Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Storage

Keep Dabixxa-110 Capsule out of the sight and reach of children.
Side effects of Dabixxa-110 Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid other medicines that increase the risk of bleeding.
  • Use an electric razor and a soft-bristled toothbrush.
  • Monitor for signs of bleeding like bleeding gums, unusual bruising, blood in stool, nosebleeds, or heavy menstrual bleeding.
  • If you experience severe bleeding, apply direct pressure on the wound and consult a doctor promptly.
  • If the risk of bleeding is high, discuss with your doctor about possibility of switching to different medicine with a lower bleeding risk.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Dabixxa-110 Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Dabixxa-110 Capsule may include an increase in the risk of bleeding. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are known to be allergic to Dabixxa-110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabixxa-110 Capsule . Dabixxa-110 Capsule is not recommended for children less than 18 years of age as the Safety and effectiveness have not been established. If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabixxa-110 Capsule . You should inform the doctor that you are taking Dabixxa-110 Capsule if you are due to undergo surgery. Avoid consumption of alcohol while taking Dabixxa-110 Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilateDeferasirox
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Dabixxa-110 Capsule:
When Mifepristone is taken with Dabixxa-110 Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Dabixxa-110 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateDeferasirox
Severe
How does the drug interact with Dabixxa-110 Capsule:
Combining Dabixxa-110 Capsule with Deferasirox can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Dabixxa-110 Capsule with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateAspirin
Severe
How does the drug interact with Dabixxa-110 Capsule:
Using dabigatran with aspirin, may enhance the risk of bleeding problems.

How to manage the interaction:
Although there is a possible interaction between aspirin and Dabixxa-110 Capsule, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, inform a doctor immediately. Do not stop using any medications without consulting doctor.
Dabigatran etexilateFosphenytoin
Severe
How does the drug interact with Dabixxa-110 Capsule:
When Dabixxa-110 Capsule is taken with Fosphenytoin, it can lower the rate at which the body breaks down Dabixxa-110 Capsule. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Fosphenytoin with Dabixxa-110 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms like sudden breathlessness, sharp chest pain, throbbing, cramping pain, swelling, redness or warmth in legs or arms, it's important to let your doctor know right away. They can recommend other options that won't cause any problems with your current medications. Do not discontinue any medications without first consulting your doctor.
Dabigatran etexilateAcalabrutinib
Severe
How does the drug interact with Dabixxa-110 Capsule:
Taking Dabixxa-110 Capsule with Acalabrutinib can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabixxa-110 Capsule with Acalabrutinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateDiclofenac
Severe
How does the drug interact with Dabixxa-110 Capsule:
Concomitant use of diclofenac with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking diclofenac with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
Dabigatran etexilateAlteplase
Severe
How does the drug interact with Dabixxa-110 Capsule:
Taking Dabixxa-110 Capsule with Alteplase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabixxa-110 Capsule with Alteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateAbciximab
Severe
How does the drug interact with Dabixxa-110 Capsule:
Taking Dabixxa-110 Capsule with Abciximab can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabixxa-110 Capsule with Abciximab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateDasatinib
Severe
How does the drug interact with Dabixxa-110 Capsule:
Coadministration of Dasatinib with Dabixxa-110 Capsule can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Dasatinib with Alteplase can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - like dizziness; red or black, tarry stools; severe headache; and weakness contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Dabigatran etexilateCarbamazepine
Severe
How does the drug interact with Dabixxa-110 Capsule:
Taking Dabixxa-110 Capsule with carbamazepine may significantly reduce the blood levels of dabigatran, which may make the medication less effective.

How to manage the interaction:
Although taking carbamazepine and Dabixxa-110 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Dabixxa-110 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Dabixxa-110 Capsule treatment.

Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Dabixxa-110 Capsule Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Dabixxa-110 Capsule as it may increase the risk of bleeding.

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Pregnancy

Caution

Please consult your doctor if you are planning to become pregnant or already pregnant before starting Dabixxa-110 Capsule . Your doctor will prescribe Dabixxa-110 Capsule only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Dabixxa-110 Capsule . Consult your doctor if you have nay concerns.

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Driving

Safe if prescribed

Dabixxa-110 Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dabixxa-110 Capsule . However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Dabixxa-110 Capsule . However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Dabixxa-110 Capsule is not recommended for children below the age of 18 years as the safety and efficacy of Dabixxa-110 Capsule have not been established in children.

FAQs

Dabixxa-110 Capsule is used to prevent blood clot formation, deep vein thrombosis (blood clots in deep veins), and pulmonary embolism (blood clots in the lungs).

Dabixxa-110 Capsule is a thrombin inhibitor. The inhibition of thrombin, reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.

Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Dabixxa-110 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Taking Dabixxa-110 Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Dabixxa-110 Capsule .

Dabixxa-110 Capsule may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.

No, you are not recommended to stop taking Dabixxa-110 Capsule without consulting your doctor as it may worsen the condition. Therefore, take Dabixxa-110 Capsule for as long as your doctor has prescribed it.

Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.

You can take Dabixxa-110 Capsule with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.

Take Dabixxa-110 Capsule as prescribed by your doctor. Depending on your medical conditions, you are advised to take Dabixxa-110 Capsule as long as your doctor has prescribed it for you.

You are recommended to avoid consumption of alcohol with Dabixxa-110 Capsule as it may increase the risk of bleeding.

Hair loss is not a known side effect of Dabixxa-110 Capsule . However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor guide you on how to cope with this situation.

It varies from person to person and depends on the conditions that we treat.

Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dabixxa-110 Capsule . However, it is not recommended in patients with severe liver diseases.

Store in a cool and dry place away from sunlight. Keep Dabixxa-110 Capsule out of the sight and reach of children.

Yes, bleeding is the main risk associated with Dabixxa-110 Capsule treatment; patients should be monitored for signs of bleeding.

Dabixxa-110 Capsule is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Dabixxa-110 Capsule .

Common side effects of Dabixxa-110 Capsule may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Country of origin

India

Manufacturer/Marketer address

D-502, Laxmi Narayan, Thane (W), Thane - 400610, Maharashtra India
Other Info - DAB0425

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:55 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/mtm/dabigatran.html
  2. https://www.nhs.uk/medicines/dabigatran/
  3. https://www.medicines.org.uk/emc/files/pil.6229.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022512s007lbl.pdf

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