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Daparyl-V 10/100 Tablet is used to treat type-2 diabetes mellitus. It contains Dapagliflozin and Sitagliptin. Dapagliflozin lowers blood glucose levels and increases glucose excretion in the urine. By improving insulin levels and lowering glucagon levels (the hormone that raises blood glucose levels), sitagliptin decreases the amount of glucose the liver produces. Thus, it helps control blood sugar levels. Common side effects of this medicine include diarrhoea, hypoglycaemia, headache, nausea, and vomiting.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Daparyl-V 10/100 Tablet

Daparyl-V 10/100 Tablet is an oral prescription tablet used to lower blood sugar levels in adults with type 2 diabetes. This medication contains a combination of two active therapies that work together to help control blood glucose. It is prescribed as an addition to diet and exercise to help manage diabetes.

To achieve the best results, you must take Daparyl-V 10/100 Tablet consistently every day at the same time, exactly as your doctor instructs. You can take this tablet with or without food, though taking it with a meal may prevent an upset stomach. Incorporating a balanced, low-sugar diet and a regular exercise routine is essential to help the medication work effectively.

While taking this medication, you may experience common, mild side effects like a runny nose, sore throat, or mild urinary tract infections. However, you must contact your doctor immediately if you experience serious side effects, such as severe, persistent stomach pain or signs of dehydration.

Before starting Daparyl-V 10/100 Tablet , talk to your doctor if you have a history of kidney disease, pancreas problems, or heart failure. Do not take this if you have type 1 diabetes, diabetic ketoacidosis, or severe kidney impairment, as it is not designed to treat these conditions.

This medicine can interact with certain blood pressure pills or other diabetes medications, which can increase the risk of low blood sugar or dehydration. You should avoid heavy alcohol consumption because it can increase your risk of severe pancreas irritation or blood sugar fluctuations. Pregnant women, breastfeeding mothers, and elderly individuals should consult their doctor before starting Daparyl-V 10/100 Tablet to ensure it is safe for them.

Uses of Daparyl-V 10/100 Tablet

Daparyl-V 10/100 Tablet is used in the treatment of type-2 diabetes mellitus. The detailed uses of Daparyl-V 10/100 Tablet are as follows:

  • Type 2 Diabetes Mellitus: Daparyl-V 10/100 Tablet helps lower daily blood sugar levels by aiding the kidneys in removing excess sugar through urine, helping the pancreas release more insulin, and reducing the amount of sugar the liver produces.

Key Benefits

Daparyl-V 10/100 Tablet helps improve blood sugar control in adults with type 2 diabetes when used alongside a healthy diet and regular exercise.
Benefits may include:

  • It helps keep blood sugar within your target range and can help improve day-to-day well-being and reduce the risk of diabetes-related complications over time.
  • By keeping your blood sugar stable throughout the day, Daparyl-V 10/100 Tablet plays a vital role in protecting your long-term health.
  • Maintaining consistent control over your blood glucose levels helps prevent serious diabetes-related complications, such as nerve damage, kidney issues, and vision loss.
  • Additionally, this medication simplifies your treatment plan. Because it combines two active therapies into a single daily tablet, it reduces the number of pills you need to take, making it easier to stick to your daily routine.

Directions for Use

  • Take Daparyl-V 10/100 Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Daparyl-V 10/100 Tablet Works

Daparyl-V 10/100 Tablet combines two different active mechanisms to manage blood sugar. Dapagliflozin: It targets your kidneys. It stops your kidneys from absorbing sugar back into your blood, which allows your body to filter out excess sugar and release it when you urinate. Sitagliptin: It works on your digestive system and pancreas. It helps your pancreas release more insulin after you eat, which allows your cells to use sugar more effectively. At the same time, it tells your liver to make less sugar, helping to keep your fasting blood sugar in check.
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Alcohol

Unsafe

Avoid consumption of alcohol during treatment with Daparyl-V 10/100 Tablet as it may cause serious side effects.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before starting treatment with Daparyl-V 10/100 Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Daparyl-V 10/100 Tablet on breastfeeding. Hence, if you are a nursing mother, inform your doctor before taking Daparyl-V 10/100 Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Daparyl-V 10/100 Tablet may occasionally cause dizziness. Hence, drive only if you are alert after taking this medicine.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Daparyl-V 10/100 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Daparyl-V 10/100 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Daparyl-V 10/100 Tablet is not recommended for use in children below 12 years of age as the safety and efficacy are not established.

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Heart

Safe

Daparyl-V 10/100 Tablet is safe to be used in heart conditions. This medicine shows potential benefits in patients with heart failure and other associated conditions.

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Geriatrics

Safe

Daparyl-V 10/100 Tablet is not generally contraindicated in elderly patients, but caution is advised, and it should be used with careful consideration of potential risks and benefits.

What if I have taken an overdose of Daparyl-V 10/100 Tablet

If you suspect an overdose, seek immediate medical attention or contact a poison control center right away. Symptoms of an overdose may include extreme weakness, shakiness, sweating, or severe dizziness.

Diet & Lifestyle Advise

  • Monitor your carbohydrate intake: Focus on eating complex carbohydrates, like whole grains and non-starchy vegetables, to prevent sudden spikes in your blood sugar.
  • Stay well-hydrated: Because this medication helps your body remove sugar through your urine, you may lose more fluids than usual. Drink plenty of water throughout the day to prevent dehydration.
  • Engage in regular physical activity: Aim for at least 150 minutes of moderate exercise, like brisk walking, per week to help your body use insulin more effectively.
  • Check your feet daily: People with diabetes are prone to foot issues. Wash your feet daily, dry them thoroughly, and inspect them for any cuts, sores, or red spots.
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How Soon It Starts Working

The time required for Daparyl-V 10/100 Tablet to start to work: Daparyl-V 10/100 Tablet ideally shows its action within few hours after administration. The time for which the effects of Daparyl-V 10/100 Tablet last: The effect of Daparyl-V 10/100 Tablet lasts for 24 hours.

What if you forget to take Daparyl-V 10/100 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular routine. Do not take a double dose to make up for a missed one.

Storage

•Store Daparyl-V 10/100 Tablet at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Observe your breathing and energy levels: Report any rapid breathing, deep fatigue, or sudden confusion immediately, as these can be warning signs of a serious condition called diabetic ketoacidosis.
  • Practice good daily hygiene: Because this medication increases sugar in your urine, maintaining clean, dry skin in genital areas is vital to prevent fungal infections.
  • Check your kidney function regularly: Ensure you attend all scheduled blood and urine tests so your doctor can monitor how well your kidneys are filtering this medication.
  • Carry a fast-acting sugar source: Always keep fruit juice, honey, or glucose tablets with you in case you experience sudden symptoms of low blood sugar when taking this with other diabetes medicines.

Drug-Drug Interactions

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  • Insulin and sulfonylureas: Taking Daparyl-V 10/100 Tablet with these medications can increase the risk of low blood sugar (hypoglycemia). Your doctor may need to adjust your doses.
  • Diuretics (water pills): These can increase your risk of dehydration and low blood pressure when taken alongside Daparyl-V 10/100 Tablet .
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Alcohol: Avoid heavy alcohol consumption, as it can increase the risk of low blood sugar and raise the risk of a dangerous condition called ketoacidosis or pancreatitis.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Daparyl-V 10/100 Tablet is used to treat type-2 diabetes mellitus. Type-2 diabetes mellitus (also known as non-insulin-dependent diabetes or adult-onset diabetes) is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.
Low-fibre diets, high-fat diets, sugary diets, obesity, smoking, stress, lack of exercise, age, genetic factors, and certain medical conditions are the common causes of diabetes.
Daparyl-V 10/100 Tablet is a combination medicine containing Sitagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin lowers blood glucose levels and increases the excretion of glucose in the urine. By increasing insulin levels and lowering glucagon levels (the hormone that raises blood glucose levels), sitagliptin decreases the amount of glucose the liver produces.
You should not take Daparyl-V 10/100 Tablet during pregnancy, especially during the second and third trimesters, as it may harm an unborn baby. If you are planning a pregnancy or become pregnant, talk to your doctor immediately to discuss alternative treatments.
Some people may experience mild weight loss when taking Daparyl-V 10/100 Tablet because one of its components helps release excess sugar and calories through urine. However, this medication is not a weight-loss drug. Talk to your doctor to understand what to expect.
While Daparyl-V 10/100 Tablet is unlikely to cause low blood sugar on its own, it can happen if you take it with other diabetes medications. If you feel shaky, sweaty, or dizzy, consume a fast-acting sugar source like fruit juice or hard candy, and talk to your doctor.
It is best to avoid or strictly limit alcohol while taking Daparyl-V 10/100 Tablet because alcohol can increase the risk of severe complications like low blood sugar or pancreas inflammation. Talk to your doctor about safe alcohol consumption limits.
One of the active ingredients in Daparyl-V 10/100 Tablet works by filtering excess sugar out of your blood and removing it through your urine, which naturally increases the amount and frequency of urination. Talk to your doctor if this becomes problematic.
Yes, because Daparyl-V 10/100 Tablet increases the amount of sugar in your urine, it creates an environment where yeast can grow more easily, potentially leading to genital yeast infections. Talk to your doctor if you experience redness, itching, or discharge.
Yes, Daparyl-V 10/100 Tablet is designed to work alongside a healthy diet and regular exercise, not replace them. Following your dietary plan is essential for successfully managing your blood sugar levels. Talk to your doctor or a dietitian for personalised advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad – 380054. Gujarat. India
Other Info - DAP0508
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