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  3. Dapavel-M 10/500 Tablet 10's

Dapavel-M 10/500 Tablet 10's, Pack of 10 TabletS
Dapavel-M 10/500 Tablet 10's, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

DAPAVEL-M 10/500 TABLETS is used to treat type 2 diabetes mellitus. It contains Metformin and Dapagliflozin which work by eliminating excess sugars from the body through urine and restoring the body's response to insulin. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, headache, and dizziness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

DAPAGLIFLOZIN-10MG + METFORMIN-500MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About DAPAVEL-M 10/500 TABLETS

DAPAVEL-M 10/500 TABLETS is used to treat Type 2 diabetes. Type 2 diabetes is a common condition that causes the level of glucose (sugar) in the blood to become too high. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups to lead a normal life.

DAPAVEL-M 10/500 TABLETS is composed of dapagliflozin and metformin. This medicine works by blocking the sodium-glucose co-transporter-2 (SGLT-2) enzyme. This lowers renal reabsorption of glucose and increases urine excretion of glucose via inhibiting SGLT2.

In some cases, you may experience specific common side effects, such as frequent urination, mild skin rash or itchy skin, or diarrhoea, stomach ache, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. The dosage is based on your medical condition and response to treatment. To help you remember, take it at the same time each day. Tell your doctor if your condition does not improve or worsens (if your blood sugar is too high or too low).

Do not take DAPAVEL-M 10/500 TABLETS if you are allergic to any component present in DAPAVEL-M 10/500 TABLETS . If you are pregnant or breastfeeding, consult your doctor before taking DAPAVEL-M 10/500 TABLETS . Avoid drinking alcohol while taking DAPAVEL-M 10/500 TABLETS since it may produce unpleasant side effects. Before starting DAPAVEL-M 10/500 TABLETS , let your doctor know if you have any history of heart, kidney or liver disease; breathing problems; blood disorders; dehydration; alcohol use, low blood pressure; and yeast infection of the genitals. DAPAVEL-M 10/500 TABLETS should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease.

Uses of DAPAVEL-M 10/500 TABLETS

DAPAVEL-M 10/500 TABLETS is used to treat high blood sugar levels in individuals with type 2 diabetes mellitus. The detailed uses of DAPAVEL-M 10/500 TABLETS are as follows: 

  • Treatment of type 2 diabetes mellitus: DAPAVEL-M 10/500 TABLETS helps control high blood glucose levels in adults with type 2 diabetes by improving insulin sensitivity, decreasing glucose production in the liver, and promoting glucose excretion through urine.
  • Improvement of glycaemic control: DAPAVEL-M 10/500 TABLETS increases insulin sensitivity and reduces glucose production in the liver.
  • Diet and exercise: DAPAVEL-M 10/500 TABLETS is prescribed along with lifestyle modifications to improve blood sugar control.

Directions for Use

  • Take DAPAVEL-M 10/500 TABLETS with meals or as advised by your doctor.
  • It is advised to take DAPAVEL-M 10/500 TABLETS once daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

Medicinal Benefits

  • DAPAVEL-M 10/500 TABLETS treats type 2 diabetes mellitus and contains Metformin and Dapagliflozin.
  • Metformin is considered a unique antidiabetic drug since it does not cause hypoglycemia (lowered blood sugar levels). It lowers your blood sugar levels by improving how your body handles insulin.
  • Dapagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine. DAPAVEL-M 10/500 TABLETS also reduces the risk of heart failure in patients with type 2 diabetes and heart disease.
  • DAPAVEL-M 10/500 TABLETS may be advised with or without other medications along with diet and exercise to control blood sugar levels.
  • It reduces blood sugar levels in people with diabetes. It does this by helping remove excess sugar from your body through your pee.
  • DAPAVEL-M 10/500 TABLETS also helps to prevent serious complications of diabetes such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), loss of sensation in your hands and feet (Diabetic Neuropathy) or even loss of a foot.

How DAPAVEL-M 10/500 TABLETS Works

DAPAVEL-M 10/500 TABLETS is composed of two antidiabetic medicines, namely: Metformin and Dapagliflozin. Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients. It exhibits a nonpancreatic effect to reduce blood glucose levels without increasing insulin secretion. Dapagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Dapavel-M 10/500 Tablet
  • Vaginal yeast infections need immediate medical attention.
  • Eat healthy foods like whole grains, lean protein and probiotics.
  • Keep your blood sugar levels in the medium range, which can help reduce the risk of yeast infections.
  • Wash your vulva well to prevent contamination, and after using the toilet, wipe from the front to prevent the spread of infection.
  • Avoid tight-fitting clothes as they may increase moisture and heat in the affected area. Ensure to use cotton underwear only.
  • Frequently change pads or tampons and always keep the effects dry.
  • Avoid sprays, perfumes and deodorants in the vaginal area, as they can change the normal balance of organisms in the vagina.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of DAPAVEL-M 10/500 TABLETS

Take DAPAVEL-M 10/500 TABLETS only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Overdose may cause low blood sugar (extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Before taking this medication, tell your doctor or pharmacist if you are allergic to dapagliflozin and metformin or have other allergies.
  • This product may contain inactive ingredients that can cause allergic reactions or other adverse effects.
  • DAPAVEL-M 10/500 TABLETS should not be stopped even if you feel better, without consulting your doctor, as your sugar level keeps changing.
  • If you stop taking DAPAVEL-M 10/500 TABLETS abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy).
  • DAPAVEL-M 10/500 TABLETS should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease.
  • It's generally not recommended to take dapagliflozin during pregnancy/breastfeeding. Discuss the risks and benefits with your doctor.
  • DAPAVEL-M 10/500 TABLETS is only for adults (above 18 years). It is not recommended for anyone aged 85 years or older.
  • It may be harder to control your blood sugar when your body is stressed (such as when you have a fever, infection, injury, or surgery).
  • Also, if you eat less or cannot eat due to these conditions or any illness, this can lead to other side effects while taking this medication. 

Drug-Drug Interactions

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MetforminIomeprol
Critical
MetforminIobitridol
Critical

Drug-Drug Interactions

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MetforminIomeprol
Critical
How does the drug interact with Dapavel-M 10/500 Tablet:
Co-administration of Iomeprol with Dapavel-M 10/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dapavel-M 10/500 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIobitridol
Critical
How does the drug interact with Dapavel-M 10/500 Tablet:
Co-administration of Dapavel-M 10/500 Tablet and Iobitridol can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Dapavel-M 10/500 Tablet with Iobitridol is generally avoided as it can result in an interaction. Please consult your doctor before taking it.
MetforminIoglicic acid
Critical
How does the drug interact with Dapavel-M 10/500 Tablet:
Co-administration of Ioglicic acid with Dapavel-M 10/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dapavel-M 10/500 Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoversol
Critical
How does the drug interact with Dapavel-M 10/500 Tablet:
Co-administration of Ioversol with Dapavel-M 10/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dapavel-M 10/500 Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Dapavel-M 10/500 Tablet:
Co-administration of Iohexol with Dapavel-M 10/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dapavel-M 10/500 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Dapavel-M 10/500 Tablet:
Co-administration of Iopromide with Dapavel-M 10/500 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Dapavel-M 10/500 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIopanoic acid
Critical
How does the drug interact with Dapavel-M 10/500 Tablet:
Co-administration of Iopanoic acid with Dapavel-M 10/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dapavel-M 10/500 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminMetrizamide
Critical
How does the drug interact with Dapavel-M 10/500 Tablet:
Co-administration of Dapavel-M 10/500 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Dapavel-M 10/500 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIoglycamic acid
Critical
How does the drug interact with Dapavel-M 10/500 Tablet:
Co-administration of Ioglycamic acid with Dapavel-M 10/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dapavel-M 10/500 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Dapavel-M 10/500 Tablet:
Co-administration of Iopydol with Dapavel-M 10/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dapavel-M 10/500 Tablet with Iopydol is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take DAPAVEL-M 10/500 TABLETS for more than once per day. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take DAPAVEL-M 10/500 TABLETS .
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
  • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods, avoiding carbonated drinks and foods that cause gas. 

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

DAPAVEL-M 10/500 TABLETS Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

It is advised to avoid alcohol intake since it may worsen the side effects like lactic acidosis and increase the risk of developing low blood sugar levels.

bannner image

Pregnancy

Unsafe

Dapagliflozin in DAPAVEL-M 10/500 TABLETS is not recommended during the second or third trimester of pregnancy. Your doctor may suggest other medications to control your blood sugar levels. Please consult your doctor before starting DAPAVEL-M 10/500 TABLETS if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

DAPAVEL-M 10/500 TABLETS may be unsafe to use during breastfeeding since it is excreted into the breast milk. Please seek medical advice for further information.

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Driving

Unsafe

Your driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience blurred vision, dizziness or drowsiness due to extremely low or high blood sugar.

bannner image

Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases or hepatic impairment when prescribed DAPAVEL-M 10/500 TABLETS .

bannner image

Kidney

Unsafe

DAPAVEL-M 10/500 TABLETS is contraindicated in patients with severe renal impairment/kidney diseases. Let your doctor know if you have any history of kidney diseases when you are prescribed DAPAVEL-M 10/500 TABLETS .

bannner image

Children

Unsafe

DAPAVEL-M 10/500 TABLETS is not recommended for people younger than 18 years of age.

Have a query?

FAQs

DAPAVEL-M 10/500 TABLETS belongs to the class of antidiabetic drugs, primarily used to treat type 2 diabetes mellitus with a proper diet and exercise. DAPAVEL-M 10/500 TABLETS also lowers the risk of heart failure in type 2 diabetic patients with heart diseases.

DAPAVEL-M 10/500 TABLETS contains two antidiabetic medicines: Metformin and Dapagliflozin. These drugs lower the blood sugar levels in type 2 diabetes mellitus by eliminating excess sugars through urine and also by increasing the activity of insulin.

DAPAVEL-M 10/500 TABLETS may cause low blood sugar levels (hypoglycaemia) and can make you hungry, dizzy, irritable, confused, anxious, or shaky. Hence, it is advised to take DAPAVEL-M 10/500 TABLETS with a meal. To immediately treat hypoglycaemia, it is advised to eat or drink fast-acting sugar sources like fruit juices, hard candy, raisins or non-diet soda.

Your doctor may advise DAPAVEL-M 10/500 TABLETS with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to achieve the controlled blood sugar levels while using DAPAVEL-M 10/500 TABLETS with or without other antidiabetic drugs.

DAPAVEL-M 10/500 TABLETS should be used with caution in heart, kidney or liver diseases, breathing problems (asthma, obstructive lung disease), blood disorders (anaemia, vitamin B12 deficiency), dehydration, alcohol use, low blood pressure, pancreas problems/surgery, and yeast infection of genitals. DAPAVEL-M 10/500 TABLETS is contraindicated in patients with severe renal impairment and metabolic acidosis/diabetic ketoacidosis.

While using DAPAVEL-M 10/500 TABLETS , if you experience vomiting, stomach/abdominal pain, muscle cramps, sick feeling, severe tiredness, difficulty in breathing, or reduced body temperature and heartbeat, it is important to seek immediate medical help since these are the symptoms of lactic acidosis. Lactic acidosis is a rare but serious complication caused due to accumulation of metformin. It is a medical emergency and needs immediate treatment. Please consult your doctor for further information.

It is not recommended to use DAPAVEL-M 10/500 TABLETS along with water pills/diuretics. Simultaneous use of DAPAVEL-M 10/500 TABLETS and water pills causes dehydration and may increase the risk of lactic acidosis.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

The side effects of DAPAVEL-M 10/500 TABLETS include headache, nausea, vomiting, diarrhoea, runny or stuffy nose, sore throat and genital infections. If these side effects persist or worsen, please consult your doctor.

You are recommended to consult your doctor before taking DAPAVEL-M 10/500 TABLETS with insulin as it may increase the risk of hypoglycemia (low blood sugar). You may need a dose adjustment or regular monitoring of blood sugar to use these medicines safely.

No, avoid taking DAPAVEL-M 10/500 TABLETS if you have any kidney problems, as it works by excreting excess sugar through urine.

No, usually DAPAVEL-M 10/500 TABLETS does not cause loss of body weight. On the other hand, rapid loss of body weight is a sign of a Diabetic ketoacidosis, a serious medical condition.

No, DAPAVEL-M 10/500 TABLETS is only useful in type 2 diabetes mellitus, in which the body either produces less amount of insulin or cannot utilise it.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - DAP0097

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 1:54 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/mtm/dapagliflozin-and-metformin.html#uses
  2. https://www.medicines.org.uk/emc/files/pil.7612.pdf
  3. https://www.webmd.com/drugs/2/drug-167198/dapagliflozin-metformin-oral/details

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