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compositionComposition:DAPTOMYCIN-350MG
prescription
Prescription Medicine
info
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Daptocin 350 mg Injection 1's is used to treat bacterial infections. It contains Daptomycin, which belongs to the cyclic lipopeptide class of antibiotics, which works by inhibiting the process of bacterial cell wall synthesis that is required for its survival. Thus, it kills bacteria and prevents the growth of bacterial infection. Common side effects of Daptocin 350 mg Injection 1's may include injection site reactions, rash, vomiting, allergic reaction, chest pain, hypotension, increased sweating, difficulty sleeping, dizziness, sore throat, nausea, and diarrhoea.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DAPTOMYCIN-350MG

Manufacturer/Marketer :

Lyka Labs Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-29

Return Policy :

Not Returnable

About Daptocin 350 mg Injection 1's

Daptocin 350 mg Injection 1's is an injectable antibiotic used to treat serious bacterial infections affecting the skin and deeper tissues, as well as infections in the bloodstream. It belongs to a class of medicines that specifically target and eliminate complex bacterial pathogens, preventing severe infections from spreading. By delivering the medication directly into the body, it provides a fast-acting defence against hard-to-treat bacteria.

Because this medicine is given directly into a vein, it is typically injected once daily at the same time each day to maintain a steady level in your system. It does not depend on food intake because it bypasses your digestive system entirely. To support your body's recovery during treatment, it is highly recommended to stay well-hydrated, eat a balanced diet, and get plenty of rest.

Before starting your treatment, talk to your doctor if you have kidney disease; your doctor may check your kidney function and adjust your dose or how often you receive this medicine if needed or a history of muscle disorders or are currently taking other prescription drugs. Do not take this if you have had a severe allergic reaction to this medication in the past. Your healthcare team will evaluate your health history to ensure this is the safest option for you.

This medication can interact with other substances, including cholesterol-lowering statins, which can increase the risk of muscle damage when taken together. It is also important to talk to your doctor if you are pregnant, breastfeeding, or are an older adult, as your dosing schedule may need to be carefully adjusted and monitored. This medicine may be used in children when prescribed by a specialist. The dose is based on the child's age, weight, and the type of infection, and treatment should be given under close medical supervision. 

Uses of Daptocin 350 mg Injection 1's

Your doctor may recommend this medicine to help manage the following conditions:

  • Complicated skin and skin structure infections: It helps clear deep, severe bacterial infections in the skin and underlying soft tissues, allowing the skin to heal properly.
  • Bloodstream infections: It targets and eliminates bacteria circulating in the blood, preventing the infection from spreading to other vital organs.
  • Right-sided infective endocarditis: It assists in treating serious bacterial infections that affect the valves on the right side of the heart.

Key Benefits

When taken consistently as directed, this medicine may provide the following physiological benefits:

  • Treats serious bacterial infections: This medicine helps treat severe bacterial infections by killing or stopping the growth of bacteria. Given directly into a vein, it reaches the bloodstream quickly, helping control the infection faster and relieve symptoms such as fever, pain, and swelling.
  • Helps prevent complications: By controlling the infection early, this medicine helps reduce the risk of the infection spreading to other parts of the body. This supports recovery, may shorten hospital stays, and helps improve overall treatment outcomes.
Side effects of Daptocin 350mg Inj
  • Eat fatty fish rich in omega-3 fatty acids to reduce inflammation.
  • Add whole grains such as brown rice, quinoa, and whole wheat bread to your diet for a nutritional boost.
  • Add nuts and seeds like almonds, walnuts, chia seeds for anti-inflammatory benefits.
  • Eat dark leafy greens like spinach, kale, collard greens for antioxidants.
  • Include berries like blueberries, strawberries, raspberries for anti-inflammatory properties.
  • Rest and take a break from usual activities.
  • Apply ice for 15-20 minutes, 3 times a day to reduce pain and inflammation.
  • Use compression with a stretchable bandage or wrap to lessen swelling and provide support.
  • Avoid strenuous activities and rest the affected area.
  • Try light stretching with gentle exercises to maintain flexibility.
  • Consider OTC pain medications like ibuprofen or acetaminophen but consult a doctor before taking any medication.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Daptocin 350 mg Injection 1's will be administered in the hospital setting by a trained healthcare professional.
  • Do not self-administer.

How Daptocin 350 mg Injection 1's Works

This medicine contains Daptocin 350 mg Injection 1's as an active ingredient. It works by binding directly to the outer membrane of certain Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Once attached, it disrupts the electrical balance of the bacterial cell membrane, causing essential substances to leak out. This prevents the bacteria from making vital components such as DNA, RNA, and proteins, so they can no longer grow or survive and eventually die. Because it targets bacteria that may not respond to some commonly used antibiotics, it is often used to treat serious bacterial infections. This rapid action helps your body's natural immune system clear the infection more effectively.
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Alcohol

Unsafe

Avoid consumption of alcohol while receiving treatment with Daptocin 350 mg Injection 1's as it may worsen your condition.

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Pregnancy

Caution

Limited data are available for the use of Daptocin 350 mg Injection 1's in pregnancy. Hence, this medicine should not be used in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or planning a pregnancy before receiving Daptocin 350 mg Injection 1's.

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Breast Feeding

Caution

Limited data are available for the use of Daptocin 350 mg Injection 1's in breastfeeding. Hence, this medicine should not be used in breastfeeding mothers unless clearly necessary. So, inform your doctor if you are breastfeeding your child before receiving Daptocin 350 mg Injection 1's.

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Driving

Unsafe

Avoid driving vehicles or operating machines as Daptocin 350 mg Injection 1's causes dizziness and makes you feel sleepy or dizzy.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Daptocin 350 mg Injection 1's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Daptocin 350 mg Injection 1's should be used under caution in patients with kidney disease. Inform your doctor if you have kidney problems. Your doctor will prescribe only if the benefits outweigh the risks. If prescribed, your doctor may adjust the dose based on your health condition.

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Children

Unsafe

Daptocin 350 mg Injection 1's is not recommended for use in children below 12 years of age as the safety and efficacy is not established

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Heart

Caution

If you have a pre-existing or a history of heart disease, inform your doctor before receiving Daptocin 350 mg Injection 1's. Your doctor will weigh the benefits and potential risks before prescribing this medicine.

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Geriatrics

Caution

Daptocin 350 mg Injection 1's should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Daptocin 350 mg Injection 1's

An overdose of this medication is highly unlikely when managed by healthcare professionals. If you are administering this medicine at home and suspect an overdose, or if you experience severe symptoms, seek immediate medical attention.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water throughout the day to help your kidneys efficiently process and clear the medication from your body.
  • Support your gut health: Consider eating yoghurt with active cultures or taking a probiotic supplement a few hours after your injection to help maintain healthy gut bacteria and prevent diarrhoea.
  • Rest your muscles: Avoid strenuous physical exercise or heavy lifting during your treatment, as this medication can occasionally cause muscle irritation.
  • Avoid alcohol: Limit or avoid alcohol to reduce extra strain on your liver and kidneys while they are working hard to clear the infection and the medicine.
health query

Have a query?

How Soon It Starts Working

The time required for Daptocin 350 mg Injection 1's to start to work: The exact onset time of Daptocin 350 mg Injection 1's has not been clinically established. The time for which the effects of Daptocin 350 mg Injection 1's last: The duration of Daptocin 350 mg Injection 1's effect is unknown.

What if you forget to take Daptocin 350 mg Injection 1's

Since this medication is usually given by a healthcare provider, a missed dose is rare. However, if you are receiving this treatment at home and miss a scheduled injection, contact your doctor or nurse immediately for guidance. Do not inject a double dose to make up for a missed one.

Storage

• Unopened vials of medicine must be stored in a refrigerator at 2°C to 8°C (36°F to 46°F).
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Inspect the solution: Always check the mixed liquid before injecting it. It should be clear and free of particles. Do not use the vial if the liquid is cloudy, discoloured, or contains visible floating specks.
  • Monitor your muscles: Your doctor will likely order weekly blood tests to check your muscle enzymes (CPK levels). Let them know immediately if you notice any sudden muscle pain.
  • Rotate injection sites: If you are receiving this medication through an IV line, ensure the injection site is checked regularly and rotated to prevent vein irritation.
  • Keep items sterile: If injecting at home, wash your hands thoroughly and use a fresh alcohol swab to clean all connection points to prevent introducing new bacteria.
  • Finish the full course: Complete your entire prescribed course of treatment, even if you feel completely recovered, to ensure the infection is entirely gone.

Drug-Drug Interactions

verifiedApollotooltip
  • Cholesterol-lowering medicines (Statins): Taking these with medicine can significantly increase the risk of muscle damage and weakness. Your doctor may temporarily stop your statin while you are treated with this injection.
  • Oral anticoagulants (Warfarin): This medication may affect blood clotting times when combined with certain blood thinners, requiring closer blood monitoring.
DaptomycinCholera, live attenuated
Severe
DaptomycinBCG vaccine
Severe

Drug-Drug Interactions

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DaptomycinCholera, live attenuated
Severe
How does the drug interact with Daptocin 350mg Inj:
Combining Daptocin 350mg Inj with Cholera, live attenuated vaccine may reduce the activity of the Cholera, live attenuated vaccine.

How to manage the interaction:
Although there is a possible interaction between Daptocin 350mg Inj and Cholera, live attenuated vaccine, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual side effects, contact a doctor. Let your doctor know about the antibiotic course you used since 14 days before taking the vaccine. Do not stop using any medications without first consulting a doctor.
DaptomycinBCG vaccine
Severe
How does the drug interact with Daptocin 350mg Inj:
Combining Daptocin 350mg Inj with BCG vaccine may reduce the activity of the BCG vaccine.

How to manage the interaction:
Although there is a possible interaction between Daptocin 350mg Inj and BCG vaccine, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual side effects, contact a doctor. Do not stop using any medications without first consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Daptocin 350 mg Injection 1's when used as directed.     
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Daptocin 350 mg Injection 1's is used to treat Bacterial infections.
Daptocin 350 mg Injection 1's contains daptomycin, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria.
Do not use anti-diarrhoeal medication until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhea as it may help in increasing the number of good bacteria in the intestine, which aids in digestion.
No, Daptocin 350 mg Injection 1's is not used to treat lung infections such as pneumonia caused by bacteria.
Daptocin 350 mg Injection 1's does not work against viral infection. So, it should not be taken to treat the common cold or cough. Consult your doctor if you have these symptoms.
As Daptocin 350 mg Injection 1's is injectable, it can start working soon after administration. However, Daptocin 350 mg Injection 1's may take a few days to kill the bacteria and prevent further spread of infection.
Daptocin 350 mg Injection 1's belongs to the cyclic lipopeptide class of antibiotics. It targets various types of bacteria by treating bacterial infections, including complicated skin and skin structure infections, blood infections such as bacteraemia (bacteria in the bloodstream), and right-sided infective endocarditis (inflammation of the inner lining of the heart caused by bacteria). The medication works by inhibiting bacterial cell wall synthesis, a process essential for bacterial survival. This action effectively kills bacteria and prevents the spread of the infection.
Daptocin 350 mg Injection 1's should be administered by the doctor or nurse through an intravenous route (into the vein) over 2 minutes. Do not self-administer.
Daptocin 350 mg Injection 1's is generally considered safe when used as prescribed by a doctor and do not skip the schedule of receiving Daptocin 350 mg Injection 1's. However, it may cause side effects in some individuals, so consult the doctor for personalized advice.
The side effects of Daptocin 350 mg Injection 1's include rash, injection site reactions, vomiting, allergic reaction, chest pain, hypotension, increased sweating, difficulty sleeping, dizziness, sore throat, nausea, and diarrhoea. Most of these side effects are mild and typically go away on their own over time. However, if any symptoms persist or worsen, consult the doctor immediately.
If you experience dizziness while taking Daptocin 350 mg Injection 1's, lie down for a while and then get up slowly. Moving cautiously can also help manage dizziness. Avoid coffee, cigarettes, and alcohol. Consult the doctor, if the dizziness persists or worsens.
There is limited information on the safety of using this medicine during pregnancy. It should only be used if the potential benefits outweigh the risks. Talk to your doctor if you are pregnant or planning to become pregnant.
Your doctor will check your blood weekly to monitor a muscle enzyme called creatine phosphokinase (CPK). This is done to ensure the medicine is not causing muscle irritation or damage. Talk to your doctor if you have questions about these tests.
If you develop unexplained muscle pain, tenderness, or weakness, stop activities and contact your doctor or pharmacist right away, as this could be a sign of a muscle-related side effect.
It is best to avoid alcohol during your treatment. Alcohol can strain your liver and kidneys and make it harder for your body to fight off the infection. Talk to your doctor for personalised advice.
Yes, mild diarrhoea can occur during treatment. However, if you experience severe, watery diarrhoea or stomach cramps, it could be a sign of a more serious gut infection. Contact your doctor immediately and do not take anti-diarrhoea medicines without asking them first.
Yes, but older adults may have reduced kidney function, which can affect how the body processes this medication. Doctors may monitor kidney function closely and adjust the treatment schedule if necessary. Talk to your doctor for more information.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 208385S005Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. National Center for Biotechnology Information (NCBI). Nbk470407 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  3. DrugBank Online. Db00080 Clinical & Chemical Summary. Edmonton, AB: DrugBank; 2026. [Accessed on 02 Jun. 2026]Check here
  4. MedlinePlus. A608045 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  5. Daptomycin Daptomycin. 2018Check here
  6. Merck & Co., Inc. Cubicin® 500 mg powder for solution for injection or infusion daptomycin. Electronic Medicines Compendium (EMC) [Revised in June 2022] [Accessed on 10th February 2023]Check here

Country of origin

India

Manufacturer/Marketer address

Spencer Building, ( Block B & C ),30, Forjett Street, Near Bhatia Hospital,Grant Road (West), Mumbai - 400007 India
Other Info - DAP1275
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