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compositionComposition:DARIFENACIN-7.5MG
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Prescription Medicine
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Darif Tablet is used in the treatment of overactive bladder (OAB) symptoms. It contains Darifenacin, which relaxes the urinary bladder muscles which in turn decreases the activity of the overactive bladder. It stops these sudden contractions of urinary bladder muscles thereby enabling control over urination. Thus, it increases the amount and volume of urination that can be held by your bladder. It may cause side effects such as dryness in the mouth, constipation, nausea, blurred vision, indigestion, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DARIFENACIN-7.5MG

Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Darif Tablet

Darif Tablet is an oral prescription medication used to treat the symptoms of an overactive bladder. It helps manage sudden, uncontrollable urges to urinate, frequent trips to the bathroom, and accidental urine leakage.

To get the best results, you should take Darif Tablet consistently once daily at the same time each day. You can take this tablet with or without food, swallowing it whole with a glass of water. Combining this medication with bladder training exercises and limiting caffeine can significantly improve your results.

While taking Darif Tablet , you may experience common, mild side effects like dry mouth or constipation. If you experience serious side effects, such as severe stomach pain or difficulty passing urine, you should stop taking the medicine and consult your doctor immediately.

Before starting this medication, talk to your doctor if you have liver problems, narrow-angle glaucoma, or severe stomach issues. Do not take this medicine if you experience urinary retention (inability to empty your bladder) or gastric retention (slow stomach emptying).

This medication can interact with certain anti-fungal medicines or heart drugs, which can raise the levels of Darif Tablet in your body and cause more side effects. If you are pregnant, planning to become pregnant, breastfeeding, or an older adult, talk to your doctor before using this medicine.

Uses of Darif Tablet

Darif Tablet is used to treat the symptoms of an overactive bladder. The detailed uses of Darif Tablet are as follows:

  • Overactive bladder (OAB): Darif Tablet relaxes the bladder muscles, helping to control the sudden, involuntary contractions that cause an urgent need to urinate.
  • Urge urinary incontinence: By calming bladder spasms, Darif Tablet helps prevent accidental leaking of urine before you can reach a restroom.
  • Urinary frequency and urgency: This medicine reduces the constant feeling of needing to urinate and decreases the overall number of times you must visit the bathroom during the day and night.
     

Key Benefits

Darif Tablet helps manage symptoms of an overactive bladder by improving bladder control and reducing urinary urgency. By supporting normal bladder function, it helps improve daily comfort and quality of life.

  • Helps Improve Bladder Control: By reducing involuntary bladder contractions, Darif Tablet helps decrease sudden urges to urinate, urinary frequency, and urge incontinence, allowing greater confidence during daily activities.
  • Reduces Night-Time Urination: Darif Tablet helps reduce the need to wake up frequently to urinate during the night, promoting more restful and uninterrupted sleep.
  • Supports Better Quality of Life: By improving bladder control and reducing urinary symptoms, Darif Tablet helps you participate more comfortably in work, travel, social activities, and other everyday routines.
     
Side effects of Darif Tablet
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Eat vitamin A-rich foods like fish liver, chicken, eggs, carrots, lemons, and mangoes in your diet.
  • Eat green leafy vegetables, meat, and dairy products, and increase the consumption of omega-3 fatty acids found in salmon and walnuts.
  • Examine your eyes regularly to detect any underlying issues.
  • Stay hydrated by drinking plenty of water.
  • Eat a well-balanced diet that includes more vegetables, fruits, fish, whole grains, nuts, legumes, and olive oil, and less dairy, meat, and saturated fats.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • Darif Tablet can be taken with food, or as advised by your doctor.
  • It is usually taken once a day or as directed by the doctor.
  • Swallow Darif Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Darif Tablet Works

Darif Tablet contains darifenacin. It belongs to a class of medications called anticholinergics. It works by blocking specific chemical receptors (M3 muscarinic receptors) located on the muscles of your bladder wall. Normally, when these receptors receive chemical signals from your nervous system, they tell the bladder muscles to contract, creating the urge to urinate. By blocking these signals, Darif Tablet prevents the bladder muscle from contracting too early or too often. This allows your bladder to hold more urine comfortably, reducing sudden and frequent urges.
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Alcohol

Caution

Avoid taking alcohol as it may increase the risk of dizziness.

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Pregnancy

Unsafe

Darif Tablet is a category C medicine. It should be used in pregnant women if the benefits outweigh the risks.

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Breast Feeding

Caution

Darif Tablet should be used in breastfeeding mothers only if clinically needed.

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Driving

Caution

Darif Tablet may cause dizziness and blurred vision and sleepiness. So, avoid driving or operating heavy machinery after using Darif Tablet .

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Liver

Caution

Darif Tablet should be used with caution in patients with liver diseases

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Kidney

Caution

Darif Tablet should be used with caution in patients with kidney diseases.

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Children

Unsafe

Not recommended for use in children below 18 years of age due to a lack of data on safety and efficacy.

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Heart

Caution

Patients with cardiac conditions should exercise caution when taking Darif Tablet .

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Geriatrics

Consult your doctor

Limited information available for use of Darif Tablet in elderly patients. Please consult your doctor.

What if I have taken an overdose of Darif Tablet

If you accidentally take too much, Darif Tablet , seek immediate medical attention or contact a poison control centre. Symptoms of an overdose may include severe dry mouth, extreme constipation, severe dizziness, or difficulty urinating.

Diet & Lifestyle Advise

  • Stay hydrated wisely: Avoid cutting back too much on water, as highly concentrated urine can irritate your bladder and worsen urgency. Drink moderate amounts of water throughout the day, but limit fluid intake a few hours before bedtime.
  • Avoid bladder irritants: Limit your consumption of caffeine, alcohol, artificial sweeteners, carbonated drinks, and spicy or highly acidic foods, which can trigger bladder spasms.
  • Manage constipation: Because Darif Tablet can cause constipation, eat a diet rich in fibre (fruits, vegetables, and whole grains) and stay physically active to keep your digestive system regular.
  • Practice pelvic floor exercises: Regularly performing Kegel exercises can strengthen the muscles supporting your bladder, giving you physical support to suppress sudden urges.
     

Health Queries

I have had diabetes for many years and am on insulin, but for the past 2 days, I have been passing urine very frequently during the day despite taking medicine at night. What could be the reason, and what should I do?

Vikas Singh

Vikas Singh

M Pharmacy

Frequent urination in diabetes despite insulin can be due to high sugar levels, infection, or a change in control over the last few days. Check your blood sugar regularly, stay hydrated, avoid excessive sugary foods, and note any burning, fever, or increased thirst. Keep your insulin routine consistent and do not change doses on your own. Consult a doctor to check blood sugar levels and perform a urine test to identify and manage the cause properly.

I have had diabetes for many years and am on insulin, but for the past 2 days, I have been passing urine very frequently during the day despite taking medicine at night. What could be the reason, and what should I do?

Vikas Singh

Vikas Singh

M Pharmacy

Frequent urination in diabetes despite insulin can be due to high sugar levels, infection, or a change in control over the last few days. Check your blood sugar regularly, stay hydrated, avoid excessive sugary foods, and note any burning, fever, or increased thirst. Keep your insulin routine consistent and do not change doses on your own. Consult a doctor to check blood sugar levels and perform a urine test to identify and manage the cause properly.
health query

Have a query?

How Soon It Starts Working

The time required for Darif Tablet to start to work: The time required for Darif Tablet to show its action is unknown. The time for which the effects of Darif Tablet last: The effect of Darif Tablet lasts for 24hours.

What if you forget to take Darif Tablet

If you miss a dose of Darif Tablet , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular routine. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Darif Tablet at room temperature, between 20°C to 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from direct light and moisture.

Drug Warnings

  • Watch out for heat stroke: Darif Tablet can reduce your body's ability to sweat, making it harder for you to cool down. Avoid becoming overheated during exercise, in hot weather, or when using hot tubs and saunas.
  • Check your vision: This medication may cause dry eyes or blurry vision. Be very cautious when driving, operating machinery, or performing tasks that require clear sight, especially at night.
  • Monitor your bowel habits: If you develop severe constipation that does not improve with diet changes, contact your doctor to prevent more serious bowel issues.
  • Inform your eye doctor: Let your eye specialist know you are taking Darif Tablet , especially if you are being treated or monitored for increased pressure in your eyes.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Other anticholinergic medications: Taking Darif Tablet with other medicines that have similar effects (like certain allergy drugs, muscle relaxants, or antidepressants) can increase your risk of severe dry mouth, constipation, and drowsiness.
  • Strong CYP3A4 inhibitors: Medications such as ketoconazole, itraconazole, or ritonavir can slow down how your body processes Darif Tablet , raising the drug's levels in your blood and increasing side effects.
     
DarifenacinThioridazine
Critical
DarifenacinEliglustat
Critical

Drug-Drug Interactions

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DarifenacinThioridazine
Critical
How does the drug interact with Darif Tablet:
Using thioridazine together with Darif Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm.

How to manage the interaction:
Taking Darif Tablet with Thioridazine is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medications without doctor's advise.
DarifenacinEliglustat
Critical
How does the drug interact with Darif Tablet:
Darif Tablet can significantly increase the blood levels of eliglustat. This may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Darif Tablet with Eliglustat is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not stop any medications without doctor's advise.
DarifenacinPotassium citrate
Critical
How does the drug interact with Darif Tablet:
Taking Darif Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Darif Tablet with Potassium citrate is not recommended, as it may lead to an interaction but can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DarifenacinPotassium chloride
Critical
How does the drug interact with Darif Tablet:
Taking Darif Tablet with Potassium chloride(oral capsule or tablet) can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Darif Tablet with Potassium chloride(oral capsule or tablet) is not recommended, as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop taking any medications without doctor's advise.
DarifenacinKetoconazole
Severe
How does the drug interact with Darif Tablet:
Coadministration of Ketoconazole and Darif Tablet may increase the blood levels of Darif Tablet.

How to manage the interaction:
Taking Ketoconazole with Darif Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, nausea, dry mouth, diarrhea, irritation, confusion, edema, fatigue, palpitations, heartburn, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
DarifenacinTelaprevir
Severe
How does the drug interact with Darif Tablet:
Combining Darif Tablet with Telaprevir may significantly increase the blood levels of Darif Tablet.

How to manage the interaction:
Although taking Darif Tablet and Telaprevir together can cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms like nausea, dry mouth, abdominal pain, constipation, and heartburn, contact a doctor. Do not stop using any medications without a doctor's advice.
DarifenacinDronedarone
Severe
How does the drug interact with Darif Tablet:
Combining Darif Tablet with Dronedarone may increase the blood levels of Darif Tablet.

How to manage the interaction:
Although taking Darif Tablet and Dronedarone together can cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms like nausea, dry mouth, abdominal pain, constipation, and heartburn, contact a doctor. Do not stop using any medications without a doctor's advice.
DarifenacinIdelalisib
Severe
How does the drug interact with Darif Tablet:
Combining Darif Tablet with Idelalisib may significantly increase the blood levels of Darif Tablet.

How to manage the interaction:
Although taking Darif Tablet and Idelalisib together can cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms like nausea, dry mouth, abdominal pain, constipation, and heartburn, contact a doctor. Do not stop using any medications without a doctor's advice.
DarifenacinAtazanavir
Severe
How does the drug interact with Darif Tablet:
Combining Darif Tablet with Atazanavir may significantly increase the blood levels of Darif Tablet.

How to manage the interaction:
Although taking Darif Tablet and Atazanavir together can cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms like nausea, dry mouth, abdominal pain, constipation, and heartburn, contact a doctor. Do not stop using any medications without a doctor's advice.
DarifenacinVoriconazole
Severe
How does the drug interact with Darif Tablet:
Taking Darif Tablet with Voriconazole may significantly increase the blood levels of Darif Tablet, which increases the risk of side effects.

How to manage the interaction:
Although taking Darif Tablet and Voriconazole together may result in an interaction, they can be taken together if a doctor prescribes it. However, if you experience nausea, abdominal pain, and heartburn, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit juice: Grapefruit and grapefruit juice can interfere with how your liver processes this medication, which can raise the levels of Darif Tablet in your system and make side effects more likely.
     
DARIFENACIN-7.5MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DARIFENACIN-7.5MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
The consumption of grapefruit juice with Darif Tablet may increase blood levels of Darif Tablet. Avoid consumption of Darif Tablet with grapefruit juice.

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FAQs

Darif Tablet is used in the treatment of overactive bladder (OAB) symptoms such as strong urge to urinate, frequent urination, and reduced urine flow.
Darif Tablet contains Darifenacin, which prevents the sudden bladder muscle contractions and increases the volume and amount of urine that the bladder can hold. Thus, Darif Tablet helps to control the release of urine and helps reduce symptoms of OAB like a strong need to urinate, frequent urination, and reduced urine flow.
Darif Tablet may cause blurred vision in some cases and may harm your thinking or reactions. Consult your doctor immediately if this condition persists or worsens while using this Darif Tablet .
Antifungal medicine may interact with Darif Tablet . So, inform your doctor about all the prescription and non-prescription medicines before taking Darif Tablet to avoid unwanted effects.
Dry mouth is the most common side effects of Darif Tablet , so you can drink plenty of fluids or water, suck hard candy or ice chips, chew (sugarless) gum, or use a saliva substitute. However, if you are a kidney patient before taking any fluid or electrolytes, it is better to consult a doctor.
The common side effect of the Darif Tablet is Diarrhea (a condition where you have loose, watery stools or bowel movements). Please do not panic about it. Usually, it vanishes over time as the body adjusts to the medication. If your loose motions persist longer, consult a doctor for personalized advice and management.
Edema is not a common side effect of the Darif Tablet . In rare instances, it may be experienced by some individuals. If you experience any unusual symptoms or side effects, it's important to consult your doctor for personalized advice and management.
The most common side effects of the Darif Tablet include dry mouth, constipation, nausea, blurred vision, indigestion, and headache. These side effects are usually mild and temporary and resolve as your body adjusts to the medication. However, if any side effects persist or worsen, it's essential to consult your doctor for proper guidance and care.
No, you should not crush, chew, or split Darif Tablet tablets. These are extended-release tablets designed to release the medication slowly into your body over 24 hours. Damaging the tablet can cause too much medicine to be released at once. Talk to your doctor or pharmacist if you have trouble swallowing tablets.
Yes, dry mouth is a common side effect of Darif Tablet because it blocks chemical signals that also control saliva production. Sucking on sugar-free hard candies, chewing sugarless gum, or sipping water frequently can help ease this symptom. Talk to your doctor if dry mouth becomes severe.
It is best to limit or avoid alcohol while taking Darif Tablet . Alcohol can irritate your bladder, worsening symptoms like urgency and frequency, and it can also increase any dizziness or sleepiness caused by the medication. Talk to your doctor for personalised advice.
If you have uncontrolled narrow-angle glaucoma, you must not take Darif Tablet . If you have controlled glaucoma, you may be able to take it under close monitoring. Talk to your doctor or eye specialist before starting this medication.
Constipation is a common side effect of Darif Tablet . You can manage this by eating more fibre-rich foods, staying physically active, and drinking plenty of water. If the constipation is severe, painful, or persistent, talk to your doctor or pharmacist.
There is limited information on the safety of Darif Tablet during pregnancy or breastfeeding. It should only be used if the potential benefit justifies the risk. Talk to your doctor to evaluate your options and determine what is safest for you.
No, Darif Tablet does not cure an overactive bladder, but it helps control and manage your symptoms as long as you continue to take it. Your symptoms may return if you stop taking the medication. Talk to your doctor before stopping treatment.

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Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Other Info - DAR0021
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