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  3. Dauneon 20mg Injection 1 ml

Dauneon 20mg Injection 1 ml, Pack of 1 INJECTION
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dauneon 20mg Injection 1 ml is an antineoplastic medicine used in the treatment of cancer. It contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying DNA and RNA synthesis. Thus, Dauneon 20mg Injection 1 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way, and causes cancer cell death.

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Synonym :

DAUNORUBICIN HYDROCHLORIDE

Composition :

DAUNORUBICIN-20MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Dauneon 20mg Injection 1 ml

Dauneon 20mg Injection 1 ml is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Dauneon 20mg Injection 1 ml helps to induce remission of nonlymphocytic leukemia (myelogenous, monocytic, erythroid) and acute lymphocytic leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

Dauneon 20mg Injection 1 ml contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Dauneon 20mg Injection 1 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Dauneon 20mg Injection 1 ml may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, fever, chills, and pain at the site of injection. Most of these side effects of Dauneon 20mg Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dauneon 20mg Injection 1 ml is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

Dauneon 20mg Injection 1 ml should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Dauneon 20mg Injection 1 ml. Dauneon 20mg Injection 1 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Dauneon 20mg Injection 1 ml as it may increase the risk of liver damage. This medicine may be recommended for use in children only if the benefits outweigh the risks.

Uses of Dauneon 20mg Injection 1 ml

Dauneon 20mg Injection 1 ml is used to treat certain types of blood cancers. The detailed uses of Dauneon 20mg Injection 1 ml are as follows:<br/>• Treats acute myeloid leukaemia (AML): Dauneon 20mg Injection 1 ml is used in combination with other chemotherapy drugs to manage AML, a cancer of the white blood cells.<br/>• Used for acute lymphocytic leukaemia (ALL): Dauneon 20mg Injection 1 ml is given with other chemotherapy agents to treat ALL, another type of white blood cell cancer.<br/>• Helps slow cancer growth: Dauneon 20mg Injection 1 ml works by inhibiting the growth and spread of cancer cells in the body.<br/>

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Dauneon 20mg Injection 1 ml will be administered by a trained healthcare professional.• Do not self-administer.

Medicinal Benefits

Dauneon 20mg Injection 1 ml contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Dauneon 20mg Injection 1 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

How Dauneon 20mg Injection 1 ml Works

Dauneon 20mg Injection 1 ml contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Dauneon 20mg Injection 1 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dauneon 20mg Injection 1 ml out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Dauneon 20mg Injection 1 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Exercise regularly and maintain a healthy weight.
  • Manage cholesterol and blood pressure.
  • Limit intake of caffeine and alcohol.
  • Avoid vaping and tobacco smoke.
  • Get enough sleep.
  • Talk to your doctor about antiarrhythmic drugs or other medications to treat your condition.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Dauneon 20mg Injection 1 ml

Dauneon 20mg Injection 1 ml is administered in a hospital setting under the supervision of your doctor or medical personnel. Thus, an overdose is quite improbable. While in the hospital, you will be constantly monitored to ensure that any unpleasant side effects are handled.

Drug Warnings

Dauneon 20mg Injection 1 ml should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Dauneon 20mg Injection 1 ml. Dauneon 20mg Injection 1 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Dauneon 20mg Injection 1 ml as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Dauneon 20mg Injection 1 ml may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Dauneon 20mg Injection 1 ml as it may cause infections.

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
DaunorubicinThalidomide
Severe

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
How does the drug interact with Dauneon 20mg Injection 1 ml:
Taking Dauneon 20mg Injection 1 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Dauneon 20mg Injection 1 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DaunorubicinThalidomide
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Taking thalidomide together with Dauneon 20mg Injection 1 ml may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Dauneon 20mg Injection 1 ml together can possibly result in an interaction, but it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
DaunorubicinBaricitinib
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Using baricitinib together with Dauneon 20mg Injection 1 ml may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Dauneon 20mg Injection 1 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
DaunorubicinEfavirenz
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Taking Efavirenz with Dauneon 20mg Injection 1 ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz with Dauneon 20mg Injection 1 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DaunorubicinTofacitinib
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
When Tofacitinib is taken with Dauneon 20mg Injection 1 ml, it may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Dauneon 20mg Injection 1 ml, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
DaunorubicinDisopyramide
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
The combined use of Dauneon 20mg Injection 1 ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Dauneon 20mg Injection 1 ml and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DaunorubicinNilotinib
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Coadministration of Dauneon 20mg Injection 1 ml and Nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dauneon 20mg Injection 1 ml and Nilotinib together can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like sudden dizziness, shortness of breath, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
DaunorubicinSotalol
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Using Dauneon 20mg Injection 1 ml together with sotalol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Dauneon 20mg Injection 1 ml, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
DaunorubicinCladribine
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
The combined use of cladribine with Dauneon 20mg Injection 1 ml can increase the risk of serious infections.

How to manage the interaction:
Taking Dauneon 20mg Injection 1 ml with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without talking to a doctor.
DaunorubicinHaloperidol
Severe
How does the drug interact with Dauneon 20mg Injection 1 ml:
Co-administration of Dauneon 20mg Injection 1 ml with Haloperidol can increase the risk of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dauneon 20mg Injection 1 ml with Haloperidol together can possibly result in an interaction, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Dauneon 20mg Injection 1 ml as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Dauneon 20mg Injection 1 ml Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol with Dauneon 20mg Injection 1 ml as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. If you are pregnant or planning pregnancy, inform your doctor before receiving Dauneon 20mg Injection 1 ml.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Dauneon 20mg Injection 1 ml. Your doctor may suggest you stop feeding while on treatment with this medicine.

bannner image

Driving

Unsafe

Dauneon 20mg Injection 1 ml causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving Dauneon 20mg Injection 1 ml.

bannner image

Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Dauneon 20mg Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Dauneon 20mg Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Safe if prescribed

Dauneon 20mg Injection 1 ml can be recommended for acute lymphocytic leukemia in children. Please consult your doctor. Your child's doctor may prescribe a suitable dose based on the condition and age of your child. If this medicine is given, the child should be observed carefully for any unwanted effects.

FAQs

Dauneon 20mg Injection 1 ml is used to treat lymphocytic leukemia, and Acute non-lymphocytic leukemia.

Dauneon 20mg Injection 1 ml contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

Dauneon 20mg Injection 1 ml may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Dauneon 20mg Injection 1 ml if you are planning to become a parent.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Dauneon 20mg Injection 1 ml as it may cause infections.

Yes, Dauneon 20mg Injection 1 ml is a vesicant (irritant) which means, it can cause severe tissue damage if it leaks into the surrounding tissues during injection (extravasation).

Dauneon 20mg Injection 1 ml should be administered by the doctor or nurse through an intravenous route (into a vein). Do not self-administer.

The frequency and duration of treatment may vary depending on your medical condition being treated. Always follow the doctor's instructions regarding the dosing schedule to get full benefits.

The side effects of Dauneon 20mg Injection 1 ml include mouth ulcers, diarrhoea, vomiting, nausea, loss of appetite, dizziness, weakness, fever, chills, and pain at the site of injection. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - DAU0010

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:04 AM IST

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Reference

  1. https://go.drugbank.com/drugs/DB00694
  2. https://www.drugs.com/pro/daunorubicin.html#s-34084-4
  3. https://medlineplus.gov/druginfo/meds/a682289.html
  4. https://reference.medscape.com/drug/daunorubicin-342118

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