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  3. DAXOTEL 20MG INJECTION 0.5ML

DAXOTEL 20MG INJECTION 0.5ML, Pack of 1 INJECTION
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Veda Maddala , M Pharmacy
DAXOTEL 20MG INJECTION is an anti-cancer medicine used in the treatment of breast, lung, prostate, stomach, head/neck cancers. It works by slowing down cell growth, thus preventing the cancer cells from rapidly dividing and spreading. Common side effects include injection site reactions, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, etc.
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Composition :

DOCETAXEL-20MG

Manufacturer/Marketer :

Fresenius Kabi India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About DAXOTEL 20MG INJECTION

DAXOTEL 20MG INJECTION belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

DAXOTEL 20MG INJECTION contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

DAXOTEL 20MG INJECTION will be administered by a healthcare professional. Your doctor will decide the dosage depending on your medical condition. The common side effects of DAXOTEL 20MG INJECTION include pain/swelling at the injection site, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, insomnia (sleeplessness), fever (please inform your doctor if you have fever), muscle aches, and breathlessness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not use or stop this medicine if the doctor did not advise you. Before starting DAXOTEL 20MG INJECTION , let your doctor know if you have any allergic reactions, medical history of liver or kidney diseases, heart diseases, blood pressure problems, fits, lung disorders, weak immune system, anemia, low white blood cell count, vision problems, and are receiving chemotherapy. DAXOTEL 20MG INJECTION is not indicated for use in pregnant and breastfeeding women. DAXOTEL 20MG INJECTION may make you feel dizzy and drowsy, hence do not drive or operate machinery. It is not recommended to consume alcohol along with DAXOTEL 20MG INJECTION . DAXOTEL 20MG INJECTION is not recommended for children below two years of age.

Uses of DAXOTEL 20MG INJECTION

Treatment of Cancer

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

DAXOTEL 20MG INJECTION contains Docetaxel that belongs to the family of anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent and prevents cancer cells from rapidly dividing and spreading. Docetaxel may be used alone or in combination with other chemotherapy drugs to treat breast cancer that has spread to the tissues and lymph nodes (locally advanced breast cancer) and other parts (secondary breast cancer). It is also used in prostate cancer that does not respond to hormone treatment. It is further being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers.

How DAXOTEL 20MG INJECTION Works

DAXOTEL 20MG INJECTION contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

Storage

Store in a cool and dry place away from sunlight
Side effects of Daxotel 20mg Injection 0.5ml
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Include fruits, vegetables, and whole grains in your diet.
  • Exercise regularly.
  • Quit smoking as it may increase the risk of neuropathy.
  • Getting massage therapy and acupuncture might help with pain.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.

What if I have taken an overdose of DAXOTEL 20MG INJECTION

The overdose of DAXOTEL 20MG INJECTION is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with DAXOTEL 20MG INJECTION , please inform your doctor immediately.

Drug Warnings

Inform your doctor if you have any allergic reactions to DAXOTEL 20MG INJECTION or other medications. Before starting DAXOTEL 20MG INJECTION , let your doctor know if you have any medical history of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. DAXOTEL 20MG INJECTION can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, DAXOTEL 20MG INJECTION is not indicated in pregnancy and breastfeeding women. If you are using DAXOTEL 20MG INJECTION , use reliable contraception forms to prevent pregnancy during the course. DAXOTEL 20MG INJECTION can make you feel dizzy and drowsy, thus affecting your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Avoid alcohol consumption while being treated with DAXOTEL 20MG INJECTION . DAXOTEL 20MG INJECTION is not recommended for patients younger than 18 years of age.

Drug-Drug Interactions

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DocetaxelDiltiazem
Severe
DocetaxelKetoconazole
Severe

Drug-Drug Interactions

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DocetaxelDiltiazem
Severe
How does the drug interact with Daxotel 20mg Injection 0.5ml:
When Diltiazem is taken with Daxotel 20mg Injection 0.5ml, it can slow down the breakdown of Daxotel 20mg Injection 0.5ml in the body.

How to manage the interaction:
Taking Diltiazem with Daxotel 20mg Injection 0.5ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like feeling sick, throwing up, having diarrhea, mouth sores, swelling, nerve pain, or weakness, it's important to let your doctor know. They might have other options for you that won't cause these problems. Other symptoms like feeling tired, dizzy, or having trouble breathing, losing weight, or pain when you pee should also be reported to your doctor right away. Do not stop using any medications without first talking to your doctor.
DocetaxelKetoconazole
Severe
How does the drug interact with Daxotel 20mg Injection 0.5ml:
Coadministration of Ketoconazole and Daxotel 20mg Injection 0.5ml may significantly increase the blood levels of Daxotel 20mg Injection 0.5ml. This may increase risk of side effects.

How to manage the interaction:
Although taking Ketoconazole and Daxotel 20mg Injection 0.5ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in your coughing, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, you should consult a doctor immediately. do not discontinue any medication without consulting a doctor.
DocetaxelCeritinib
Severe
How does the drug interact with Daxotel 20mg Injection 0.5ml:
Taking ceritinib and may significantly increase the blood levels of Daxotel 20mg Injection 0.5ml.

How to manage the interaction:
Taking Daxotel 20mg Injection 0.5ml with Ceritinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like nausea, vomiting, diarrhea, mouth sores, fluid retention, nerve pain, numbness, tingling, muscle pain or weakness, paleness, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to a doctor.
DocetaxelBaricitinib
Severe
How does the drug interact with Daxotel 20mg Injection 0.5ml:
Coadministration of baricitinib and Daxotel 20mg Injection 0.5ml can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Daxotel 20mg Injection 0.5ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
DocetaxelCladribine
Severe
How does the drug interact with Daxotel 20mg Injection 0.5ml:
The combined use of cladribine with Daxotel 20mg Injection 0.5ml can increase the risk of serious infections.

How to manage the interaction:
Taking Daxotel 20mg Injection 0.5ml with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
DocetaxelPosaconazole
Severe
How does the drug interact with Daxotel 20mg Injection 0.5ml:
Taking Daxotel 20mg Injection 0.5ml with posaconazole can increase the blood levels of Daxotel 20mg Injection 0.5ml. This may increase the risk of side effects.

How to manage the interaction:
Although using Posaconazole and Daxotel 20mg Injection 0.5ml together can result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience vomiting, diarrhea, mouth sores, nerve pain, numbness, tingling, muscle pain or weakness. Do not stop taking any medications without consulting a doctor.
DocetaxelRitonavir
Severe
How does the drug interact with Daxotel 20mg Injection 0.5ml:
Taking Ritonavir and Daxotel 20mg Injection 0.5ml may significantly increase the blood levels of Daxotel 20mg Injection 0.5ml.

How to manage the interaction:
Taking Daxotel 20mg Injection 0.5ml with Ritonavir together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms feeling sick, having diarrhea, sores in your mouth, retaining fluids, experiencing nerve pain, numbness or tingling, muscle pain or weakness, feeling tired, dizzy or faint, having trouble with bleeding or bruising, having a fever or chills, a sore throat, muscle aches, difficulty breathing, feeling pain or burning when you pee, or bleeding contact a doctor. Do not stop using any medications without a doctor's advice.
DocetaxelClozapine
Severe
How does the drug interact with Daxotel 20mg Injection 0.5ml:
Taking Daxotel 20mg Injection 0.5ml and clozapine can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Daxotel 20mg Injection 0.5ml and Clozapine, but it can be taken if prescribed by a doctor. If you're taking clozapine and also taking medications that can affect your bone marrow or cause agranulocytosis, be careful and get regular check-ups. If you notice any symptoms like infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain while urinating, call your doctor right away. Do not discontinue any medications without first consulting your doctor.
DocetaxelTofacitinib
Severe
How does the drug interact with Daxotel 20mg Injection 0.5ml:
Taking Tofacitinib with Daxotel 20mg Injection 0.5ml may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Daxotel 20mg Injection 0.5ml, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
DocetaxelThalidomide
Severe
How does the drug interact with Daxotel 20mg Injection 0.5ml:
Taking thalidomide together with Daxotel 20mg Injection 0.5ml may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Daxotel 20mg Injection 0.5ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Include whole grains, legumes, and follow a plant-based diet. Limiting dietary fats is advised during the breast cancer phase. Instead, include healthy fats, such as olive oil, avocado, nuts, seeds, and fatty fish
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk, and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

DAXOTEL 20MG INJECTION Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

It is unsafe to consume alcohol while using DAXOTEL 20MG INJECTION since it may cause increased dizziness and drowsiness. Please consult your doctor for more information.

bannner image

Pregnancy

Unsafe

It is unsafe to use DAXOTEL 20MG INJECTION in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using DAXOTEL 20MG INJECTION .

bannner image

Breast Feeding

Unsafe

DAXOTEL 20MG INJECTION is not recommended during breastfeeding since it may be unsafe for the breastfed infant. Please seek medical advice if you are a nursing mother before starting DAXOTEL 20MG INJECTION .

bannner image

Driving

Unsafe

DAXOTEL 20MG INJECTION causes dizziness and drowsiness that may affect your ability to drive. Do not drive or operate machinery if you experience unmanageable side effects with DAXOTEL 20MG INJECTION .

bannner image

Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment. Before being treated with DAXOTEL 20MG INJECTION , your doctor may advise you of blood tests to check your liver functioning.

bannner image

Kidney

Caution

Please let your doctor know if you have any history of kidney diseases before starting DAXOTEL 20MG INJECTION .

bannner image

Children

Unsafe

Safety and efficacy of DAXOTEL 20MG INJECTION have not been established in patients younger than 18 years.

Have a query?

FAQs

DAXOTEL 20MG INJECTION belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers.

DAXOTEL 20MG INJECTION contains Docetaxel, an anti-neoplastic agent. It prevents the cancer cells from rapidly dividing and spreading, thus slowing down their growth.

DAXOTEL 20MG INJECTION should be used with caution and under doctor's supervision only if you have any medical history of any allergic reactions, liver or kidney diseases, non-small cell lung cancer, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions (excess fluid around lungs), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Let your doctor know if you have any other medical concerns before using DAXOTEL 20MG INJECTION .

During treatment with DAXOTEL 20MG INJECTION , it is essential to look for any signs of swelling (fluid retention/oedema), dizziness/fainting, difficulty in breathing, irregular heartbeat, swelling, pain and tenderness in the abdomen region, blood in stools, skin rashes, easy bleeding or bruising, sores in the mouth or throat or symptoms of infection like fever and sore throat. If you further notice any symptoms that are not manageable or unusual, please seek prompt medical attention.

It is advised to consult your doctor before undergoing any vaccination and take advice accordingly. Also, please avoid contact with people who have recently been vaccinated with the oral polio vaccine.

DAXOTEL 20MG INJECTION might cause serious allergic reactions and fluid retention if you had previously experienced allergic reactions with paclitaxel and cabazitaxel. These medicines contain polysorbate 80, an excipient. If you had any allergic reactions with medicines containing polysorbate 80, DAXOTEL 20MG INJECTION is not recommended. Please consult your doctor for more information.

DAXOTEL 20MG INJECTION is administered through an intravenous (IV) infusion. A healthcare professional usually gives it in a medical facility.

DAXOTEL 20MG INJECTION may cause weight loss due to common side effects such as loss of appetite, nausea, vomiting, diarrhoea, and fatigue. But, in rare cases, some patients may experience fluid retention or increased hunger, which can lead to weight gain. Consult your doctor or pharmacist for personalized guidance if you have concerns about weight changes.

The duration of DAXOTEL 20MG INJECTION treatment varies depending on the type of your cancer, dose of DAXOTEL 20MG INJECTION , and your response to therapy. Typically, it is administered once every 3 weeks. Your doctor will determine the total length of treatment for you based on your specific situation.

No, it is advisable not to drink alcohol while taking DAXOTEL 20MG INJECTION . Drinking alcohol during treatment may cause increased dizziness and drowsiness.

No, DAXOTEL 20MG INJECTION is not available in pill form. It is available in two primary dosage forms: injection and powder for injection.

Before administering DAXOTEL 20MG INJECTION , certain blood tests are required to ensure safe administration. These tests include a Complete Blood Count (CBC) to check blood cell counts, blood urea nitrogen (BUN) and creatinine levels to assess kidney function, liver function tests (LFTs) to evaluate liver health, and electrolyte level checks. Additionally, other tests may be required depending on individual patient needs and medical history. These blood tests help healthcare providers assess kidney and liver function and other vital parameters to ensure that DAXOTEL 20MG INJECTION can be administered safely and effectively. Your healthcare provider will determine the necessary blood tests and monitoring requirements.

Hair loss caused by DAXOTEL 20MG INJECTION is often reversible. While DAXOTEL 20MG INJECTION can cause hair thinning or loss, hair growth returns once treatment is stopped. However, in some cases, hair loss may be permanent. Consult your healthcare provider for guidance and support if you're concerned about hair loss.

Dexamethasone is used with DAXOTEL 20MG INJECTION to avoid toxicities.

DAXOTEL 20MG INJECTION is a chemotherapy medication that belongs to the class of drugs known as anti-neoplastic/anticancer drugs. It is a cytotoxic agent that prevents the cancer cells from rapidly dividing and spreading.

DAXOTEL 20MG INJECTION causes dizziness and drowsiness that may affect your ability to drive. So, do not drive or operate machinery if you experience these.

The common side effects of DAXOTEL 20MG INJECTION may include vomiting, constipation, changes in taste, extreme tiredness, muscle, joint, or bone pain, hair loss, nail changes, increased eye tearing, sores in the mouth and throat, and redness, dryness, or swelling at the injection site. However, these symptoms usually diminish as your body adjusts to the medication. If these symptoms worsen, please consult a doctor for relief.

DAXOTEL 20MG INJECTION is generally considered safe when following your doctor's advice. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.

DAXOTEL 20MG INJECTION contains Docetaxel, which belongs to the anticancer drugs.

Safety and efficacy of DAXOTEL 20MG INJECTION have not been established in patients younger than 18 years.

Country of origin

India

Manufacturer/Marketer address

Fresenius Kabi AG? , Else-Kröner-Straße 1 ? , 61352 Bad Homburg , Germany
Other Info - DAX0002

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Author Details

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jan 1, 2025 | 2:46 PM IST

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Reference

  1. https://www.drugs.com/mtm/docetaxel.html#dosage
  2. https://www.medicines.org.uk/emc/files/pil.2464.pdf
  3. https://www.webmd.com/drugs/2/drug-4890/docetaxel-intravenous/details
  4. https://breastcancernow.org/information-support/facing-breast-cancer/going-through-treatment-breast-cancer/chemotherapy/docetaxel-taxotere
  5. https://chemocare.com/chemotherapy/drug-info/docetaxel.aspx
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