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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Defcort TM Tablet is used to treat kidney stones. Besides this, it may also help provide relief from pain, swelling, and inflammation associated with kidney stones. It works by relaxing the muscles around the bladder, thereby easing the passage of kidney stones. It also reduces inflammation in the kidneys; this promotes the passage of stones via urine.

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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Defcort TM Tablet

Defcort TM Tablet is a combination medicine used to treat kidney stones. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. Defcort TM Tablet may also help provide relief from pain, swelling, and inflammation associated with kidney stones.
 
Defcort TM Tablet contains Tamsulosin and Deflazacort. Tamsulosin relaxes the muscles around the bladder, and prostate gland, thereby eases the passage of kidney stones. Deflazacort reduces inflammation in the kidneys; this promotes the passage of stones via urine. Together, Defcort TM Tablet helps treat kidney stones.
 
You are advised to take Defcort TM Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side effects such as headache, dizziness, nausea, diarrhoea, and cold symptoms. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant or breastfeeding. Limited information is available regarding the usage of Defcort TM Tablet in children; talk to a doctor if you have any concerns. It is unknown if alcohol interacts with Defcort TM Tablet , so please consult a doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Defcort TM Tablet

Defcort TM Tablet is used in the treatment of kidney stones. The detailed uses of Defcort TM Tablet are as follows:
• Treatment of kidney stones: Defcort TM Tablet helps to treat kidney stones by relaxing the muscles around the bladder and prostate gland, thereby facilitating kidney stone passage.
• Reduces pain and inflammation: Defcort TM Tablet is involved in relieving pain and discomfort associated with kidney stones.
• Improve Urine Flow: Defcort TM Tablet improves urine flow, which facilitates the passage of small stones, and helps prevent future kidney stone formation.

Directions for Use

Take Defcort TM Tablet with food. Swallow Defcort TM Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Defcort TM Tablet is a combination of two drugs, namely: Tamsulosin and Deflazacort. Defcort TM Tablet is used to treat kidney stones. Tamsulosin is an alpha-blocker that relaxes the muscles around the bladder and prostate gland, thereby eases the passage of kidney stones. Deflazacort is a corticosteroid that reduces inflammation in the kidneys; this promotes the passage of stones via urine. Together, Defcort TM Tablet helps treat kidney stones. Defcort TM Tablet helps provide relief from pain, swelling, and inflammation associated with kidney stones.

How Defcort TM Tablet Works

Defcort TM Tablet contains Tamsulosin and Deflazacort. Tamsulosin relaxes the muscles around the bladder, and prostate gland, thereby eases the passage of kidney stones. Deflazacort reduces inflammation in the kidneys; this promotes the passage of stones via urine. Together, Defcort TM Tablet helps treat kidney stones.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Defcort TM Tablet

Take Defcort TM Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Defcort TM Tablet if you are allergic to any of its contents. Inform your doctor if you have high blood pressure, heart problems, fluid retention, diabetes, stomach/intestinal disorder, glaucoma, low bone mineral density, thyroid, adrenal gland, pituitary gland, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Let your doctor know if you are taking any prescription/nonprescription medicines or herbal products before starting Defcort TM Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Defcort TM Tablet:
Co-administration of Defcort TM Tablet and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
How does the drug interact with Defcort TM Tablet:
Co-administration of Clarithromycin with Defcort TM Tablet can increase the levels of Defcort TM Tablet in the body.

How to manage the interaction:
Taking Clarithromycin with Defcort TM Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, or fainting contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Defcort TM Tablet:
Coadministration of Darunavir with Defcort TM Tablet can increase the levels of Defcort TM Tablet in the body. This increases the risk of side effects.

How to manage the interaction:
Taking Darunavir with Defcort TM Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortFosphenytoin
Severe
How does the drug interact with Defcort TM Tablet:
Taking Fosphenytoin with Defcort TM Tablet may significantly reduce the blood levels of Defcort TM Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Fosphenytoin and Defcort TM Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Defcort TM Tablet:
Taking Rifampicin with Defcort TM Tablet may reduce the blood levels of Defcort TM Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Defcort TM Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Defcort TM Tablet:
Co-administration of Bempedoic acid and Defcort TM Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bempedoic acid can be taken with Defcort TM Tablet if prescribed by the doctor. However, consult a doctor immediately if you experience pain or swelling in joints. Avoid exercise or use of the affected area. Do not stop using any medications without talking to a doctor.
How does the drug interact with Defcort TM Tablet:
Coadministration of Atazanavir with Defcort TM Tablet can increase the levels of Defcort TM Tablet in the body. This increases the risk of side effects.

How to manage the interaction:
Taking Atazanavir with Defcort TM Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Defcort TM Tablet:
Gatifloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Defcort TM Tablet.

How to manage the interaction:
Although there is an interaction, Gatifloxacin can be taken with Defcort TM Tablet if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
DeflazacortCertolizumab
Severe
How does the drug interact with Defcort TM Tablet:
Co-administration of Defcort TM Tablet with Certolizumab may increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Defcort TM Tablet and Certolizumab, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Defcort TM Tablet:
Co-administration of Infliximab with Certolizumab may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Defcort TM Tablet and Infliximab, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids as they help in flushing out excess minerals.

  • Limit salt intake. High amounts of salt can increase the risk of kidney stones.

  • Maintain a healthy weight by exercising regularly.

  • Avoid foods rich in oxalates, such as spinach, nuts, okra, dates, avocado, hot chocolate, cocoa, baked potato, french fries, and cereals, as they might increase the risk of oxalate stones.

  • Try maintaining optimum levels of calcium in the body as too little or high calcium can lead to kidney stones.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Caution

It is not known if alcohol interacts with Defcort TM Tablet . Please consult a doctor.

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Pregnancy

Caution

Limited information is available regarding the usage of Defcort TM Tablet during pregnancy. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Defcort TM Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

It is unknown if Defcort TM Tablet affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Limited information is available regarding the usage of Defcort TM Tablet in patients with hepatic impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Limited information is available regarding the usage of Defcort TM Tablet in patients with kidney problems. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Limited information is available regarding the usage of Defcort TM Tablet in children. Consult a doctor if you have any concerns.

Have a query?

FAQs

Defcort TM Tablet is used to treat kidney stones.

Defcort TM Tablet contains tamsulosin and deflazacort. Tamsulosin relaxes the muscles around the bladder and prostate gland, thereby eases the passage of stones. Deflazacort reduces inflammation in the kidneys; this promotes the passage of stones via urine. Together, Defcort TM Tablet helps treat kidney stones.

Do not discontinue Defcort TM Tablet without consulting your doctor. To treat your condition effectually, continue taking Defcort TM Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Defcort TM Tablet .

Diarrhoea might be a side-effect of Defcort TM Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

If you miss a dose, try to take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose instead. Avoid taking a double dose as it can cause overdose or unpleasant side effects.

Weight gain could be a side effect of Defcort TM Tablet . Maintain a healthy weight by exercising regularly and eating healthy food. Talk to your doctor if you notice severe weight gain.

Defcort TM Tablet contains deflazacort; therefore, consult your doctor before taking live vaccines, as you can develop a serious infection.

Yes, Defcort TM Tablet may cause a painful erection that may last for 2 or more hours. If you experience this symptom while using Defcort TM Tablet , it is important to consult your doctor immediately.

No, taking Defcort TM Tablet in higher than the recommended dose will not be effective, rather it may cause unpleasant side effects. Therefore, always take Defcort TM Tablet in the dose exactly as prescribed by the doctor for best results and to prevent adverse effects.

Defcort TM Tablet should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

Defcort TM Tablet should be taken orally with food. Swallow it as a whole with a glass of water. Do not chew, crush or break it.

The side effects of Defcort TM Tablet include diarrhoea, headache, dizziness, nausea, and cold symptoms. Consult the doctor if any of these side effects persist or worsen.

Yes, you can take Defcort TM Tablet with other medications if prescribed by the doctor. However, consult the doctor before taking Defcort TM Tablet with these medications such as anti-hypertensive (diltiazem, metoprolol), and anti-depressant (duloxetine) as these may cause drug interactions.

Do not take Defcort TM Tablet if you are allergic to any of its ingredients. Inform your doctor if you have high blood pressure, heart issues, fluid retention, diabetes, gastrointestinal disorders, glaucoma, low bone mineral density, or problems with the thyroid, adrenal gland, pituitary gland, kidneys, or liver. Consult the doctor if you are pregnant or breastfeeding. Make sure to inform your doctor about any prescription or over-the-counter medications, as well as herbal products, you are taking before taking Defcort TM Tablet . Avoid consumption of grapefruit or grapefruit juice while using this medication, as it may cause unwanted side effects.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - DEF0088

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