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Defnalone 24 mg Tablet is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. It makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Defnalone 24 mg Tablet
Defnalone 24 mg Tablet is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally and is unable to distinguish between foreign cells and native cells. This condition results in an immune system that starts to attack native cells and organs, leading to medical problems like Duchenne muscular dystrophy.
Defnalone 24 mg Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Defnalone 24 mg Tablet binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation. Thus, Defnalone 24 mg Tablet is beneficial in autoimmune diseases and inflammation that cause harm to various organs, especially in joints with arthritis and the skin in psoriasis. Defnalone 24 mg Tablet makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy.
Defnalone 24 mg Tablet is available in both oral tablet and suspension dosage forms. The tablet form of Defnalone 24 mg Tablet can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Defnalone 24 mg Tablet can be taken as directed by your doctor, using a measuring cup. Your doctor will recommend how often you take Defnalone 24 mg Tablet based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headaches, dizziness, skin rashes, tremors, nervousness, diarrhoea, and fast heartbeats. Most of the side effects of Defnalone 24 mg Tablet do not require medical attention and usually resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, stomach upset, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may occur when the medication is stopped suddenly.
Before starting Defnalone 24 mg Tablet, please inform your doctor that you are allergic or hypersensitive to Defnalone 24 mg Tablet. Extra care is needed when a patient has an existing infection being treated (systemic infection) or has recently received live virus vaccines. A doctor's consultation is required as Defnalone 24 mg Tablet is not safe to use during pregnancy.
Uses of Defnalone 24 mg Tablet
Directions for Use
Medicinal Benefits
Defnalone 24 mg Tablet is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Defnalone 24 mg Tablet is a steroid that interacts with overactive immune cells, slows their activity, and decreases the damaging effects they cause in the body.
How Defnalone 24 mg Tablet Works
Storage
What if I have taken an overdose of Defnalone 24 mg Tablet
Drug Warnings
Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney and liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Defnalone 24 mg Tablet. This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Defnalone 24 mg Tablet. Before taking Defnalone 24 mg Tablet for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions.
Drug-Drug Interactions
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Drug-Food Interactions
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Diet & Lifestyle Advise
A patient needs to take extra care of their hygiene and stay away from places or people believed to be a cause of infection, as this drug affects the immune system. Therefore, proper care is necessary.
Habit Forming
Therapeutic Class
Product Substitutes
Alcohol
Caution
The effect of taking both alcohol and Defnalone 24 mg Tablet may lead to bleeding and ulcers in the stomach. A doctor's consultation is recommended.
Pregnancy
Unsafe
Not recommended in pregnant females.Defnalone 24 mg Tablet crosses the placenta and doses equivalent to >40 mg prednisolone daily increase the risk of fetal and neonatal damage.
Breast Feeding
Caution
No adverse effect is reported yet it is advised to have doctors' consultation by breastfeeding mothers.
Driving
Unsafe
A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.
Liver
Caution
If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Defnalone 24 mg Tablet can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Defnalone 24 mg Tablet.
Kidney
Caution
Before using Defnalone 24 mg Tablet by a kidney patient it is recommended to have a doctors consultation. It may affect the kidney in a few cases.
Children
Unsafe
Defnalone 24 mg Tablet is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Defnalone 24 mg Tablet.
Have a query?
Defnalone 24 mg Tablet is used to treat Duchene muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.
Not recommended in mild allergies. Defnalone 24 mg Tablet is recommended only after consulting a doctor, as it is a strong medicine that produces considerable side effects, and is used only in moderate to severe cases.
It is not recommended to stop by a patient himself/herself, especially by a patient undergoing organ transplantation as it may worsen the situation.
It is not recommended to be taken Defnalone 24 mg Tablet with alcohol as it may cause stomach bleeding.
No its is not recommended to be used in seasonal allergy or mild cases. Only on doctors consultation, Defnalone 24 mg Tablet may be used in extreme cases of seasonal allergy.
You should not use Defnalone 24 mg Tablet if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Defnalone 24 mg Tablet if you have a compromised immune system, eye problems or weak bones.
Yes, Defnalone 24 mg Tablet is a steroid medication. It's a corticosteroid, also known as a glucocorticoid.
Defnalone 24 mg Tablet is less potent than Prednisone and is usually administered proportionately in higher doses.
No, Defnalone 24 mg Tablet is not a painkiller. It is a steroid medication.
Yes, it can be used to treat kidney stones.
Swallow it whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.
It may be unsafe for some to use. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.
Yes, it is safe to use Defnalone 24 mg Tablet if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.
Inadequate data available on the use of this drug in pregnant women to inform a drug-related risk. So, it should be used during pregnancy only if the benefit outweighs the risk to the fetus.
Common side effects of Defnalone 24 mg Tablet may include nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Defnalone 24 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Store in a cool and dry place away from sunlight. Please keep it away from pets and children.
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