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compositionComposition:DEFLAZACORT-6MG
prescription
Prescription Medicine
info
Defoliz-6 Tablet 10's

Defoliz-6 Tablet 10's is used to treat Duchenne muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which inhibits the production of chemicals called cytokines responsible for inflammation. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DEFLAZACORT-6MG

Manufacturer/Marketer :

Evagrace Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-29

Return Policy :

Not Returnable

About Defoliz-6 Tablet 10's

Defoliz-6 Tablet 10's is a corticosteroid medication prescribed to treat a wide variety of conditions characterised by swelling, inflammation, and an overactive immune system. It is commonly used to treat Duchenne muscular dystrophy, severe asthma, arthritis, and certain skin or kidney disorders. By reducing inflammation, this medicine helps manage symptoms and prevent further tissue damage.

To get the best results, you must take Defoliz-6 Tablet 10's regularly and exactly as prescribed by your doctor. It is typically taken once daily, with or without food. However, taking your dose with a meal or a glass of milk can help prevent stomach upset. Incorporating a low-sodium, potassium-rich diet can also help manage potential fluid retention and maintain healthy mineral levels during your treatment.

While Defoliz-6 Tablet 10's is highly effective, it can cause side effects. Some of the most common issues include increased appetite, weight gain, and mild mood shifts. If you experience serious side effects, such as changes in your vision, severe muscle weakness, or signs of an infection, you should consult your doctor immediately.

Before starting this medicine, it is important to tell your doctor about your complete medical history. Do not take this if you have a known allergy to any of its ingredients or if you currently have a widespread, untreated fungal infection. You should also talk to your doctor if you have diabetes, high blood pressure, heart problems, or bone thinning (osteoporosis), as this medicine can affect these conditions.

This medicine can interact with other substances, including certain pain relievers, vaccines, and alcohol. For example, drinking alcohol while taking this medicine may increase your risk of stomach ulcers. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor or pharmacist to ensure this medication is safe for your specific situation.
 

Uses of Defoliz-6 Tablet 10's

Defoliz-6 Tablet 10's may be prescribed for the following conditions: 

  • Duchenne Muscular Dystrophy: Defoliz-6 Tablet 10's helps maintain muscle strength and delay the progression of muscle weakness in patients with this genetic disorder.
  • Severe Inflammatory Conditions: It reduces swelling, redness, and pain associated with severe joint inflammation, skin diseases, and bowel disorders.
  • Autoimmune Disorders: It calms an overactive immune system to protect organs from being attacked by the body's own defence system.
  • Allergic Reactions: It controls severe allergic responses that do not respond to other standard treatments.
     

Key Benefits

Defoliz-6 Tablet 10's helps reduce inflammation and suppress overactive immune responses, providing relief from a variety of inflammatory, allergic, and autoimmune conditions. It can help improve physical comfort and support daily functioning.

  • Reduces Inflammation: Helps decrease swelling, redness, and inflammation associated with various medical conditions.
  • Relieves Pain and Discomfort: By controlling inflammation, it may help reduce pain, stiffness, and tenderness, improving physical comfort.
  • Suppresses Overactive Immune Responses: Helps manage autoimmune and allergic conditions by reducing excessive immune system activity.
  • Supports Muscle Function: In conditions such as Duchenne muscular dystrophy, it may help preserve muscle strength and physical function for longer periods.
  • Improves Daily Functioning: Better symptom control may help improve mobility, independence, and overall quality of life.
     

Directions for Use

  • Defoliz-6 Tablet 10's can be taken with or without food.
  • It is usually taken once daily at the same time each day or as prescribed by your doctor.
  • Swallow Defoliz-6 Tablet 10's as a whole with a glass of water.
  • Do not crush or chew this medication.
  • If you cannot swallow the tablet as a whole, you may break it in half and take both halves separately.

How Defoliz-6 Tablet 10's Works

Defoliz-6 Tablet 10's contains deflazacort, a corticosteroid that works by mimicking the effects of hormones naturally produced by the adrenal glands. It helps reduce inflammation by blocking the production of substances responsible for swelling, redness, and pain, thereby protecting tissues from damage. Deflazacort also helps regulate the body's immune response. In autoimmune conditions, where the immune system mistakenly attacks healthy tissues, it suppresses this overactive activity and helps prevent further damage to joints, muscles, and other organs. Through these actions, Defoliz-6 Tablet 10's helps control inflammation and improve symptoms associated with inflammatory and autoimmune disorders.
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Alcohol

Caution

The effect of taking both alcohol and Defoliz-6 Tablet 10's may lead to bleeding and ulcers in the stomach. A doctor's consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females. Defoliz-6 Tablet 10's crosses the placenta and increases the risk of fetal and neonatal damage.

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Breast Feeding

Consult your doctor

No adverse effect is reported, yet it is advised to have a doctor's consultation for breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feel tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Defoliz-6 Tablet 10's can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Defoliz-6 Tablet 10's.

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Kidney

Consult your doctor

Before using Defoliz-6 Tablet 10's, it is recommended to have a doctor's consultation. It may affect the kidneys in a few cases.

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Children

Unsafe

Defoliz-6 Tablet 10's is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Defoliz-6 Tablet 10's.

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Heart

Caution

Defoliz-6 Tablet 10's can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Unsafe

Defoliz-6 Tablet 10's should be avoided in geriatric patients, as it can cause adverse effects like stroke, falls, or death in some patients.

What if I have taken an overdose of Defoliz-6 Tablet 10's

If you suspect an overdose or have taken more than your prescribed dose, seek immediate medical attention or contact your local poison control centre right away.

Diet & Lifestyle Advise

  • Limit sodium intake: Reduce salt in your diet to help prevent fluid retention and swelling while taking this medicine.
  • Support your bones: Eat calcium-rich foods (like dairy products or leafy greens) and ensure adequate Vitamin D intake, as long-term steroid use can weaken bones.
  • Monitor blood sugar: If you have diabetes, check your blood sugar levels regularly, as this medicine can cause blood glucose levels to rise.
  • Practice good hygiene: Wash your hands frequently and avoid close contact with people who are sick, as this medicine can lower your resistance to infections.
     

Have a query?

How Soon It Starts Working

  • The time required for Defoliz-6 Tablet 10's to start to work: Defoliz-6 Tablet 10's ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of Defoliz-6 Tablet 10's last: The effect of Defoliz-6 Tablet 10's lasts for 9 hours.

What if you forget to take Defoliz-6 Tablet 10's

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular routine. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure.

Storage

•Store Defoliz-6 Tablet 10's tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Do Not Stop Treatment Suddenly: Defoliz-6 Tablet 10's should be discontinued gradually under medical supervision to allow your body to adjust safely.
  • Carry Medical Identification: Keep a medical alert card or wear a bracelet indicating that you are taking a corticosteroid medicine.
    Avoid Live Vaccines: Do not receive live vaccines while taking Defoliz-6 Tablet 10's unless specifically advised by your doctor.
  • Inform Healthcare Providers: Tell your doctor, dentist, surgeon, or other healthcare professionals that you are taking Defoliz-6 Tablet 10's before any medical or dental procedure.
  • Monitor Weight and Blood Pressure: Check your weight and blood pressure regularly during treatment and report any significant changes to your doctor.
     

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Defoliz-6 Tablet 10's:Inform your doctor if you are taking any of the following medicines, as they may interact with Defoliz-6 Tablet 10's:
 

  • Pain Relievers (NSAIDs): Taking these with Defoliz-6 Tablet 10's can increase your risk of stomach ulcers and bleeding.
  • Antifungals and Antibiotics: Certain medications (like ketoconazole or rifampin) can alter how your body processes this medicine, requiring a dose adjustment.
  • Live Vaccines: May not work effectively or could cause a severe reaction because your immune system is suppressed.
     

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verifiedApollotooltip

Certain foods and beverages may affect how Defoliz-6 Tablet 10's works or increase the risk of side effects: 

  • Grapefruit and Grapefruit Juice: Avoid these products, as they can raise the amount of the medicine in your body and increase the risk of side effects.
     

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- INFLAMMATORY AGENTS]

FAQs

Defoliz-6 Tablet 10's is used to treat Duchenne muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.
Not recommended for mild allergies. Defoliz-6 Tablet 10's is recommended only after consulting a doctor, as it is a strong medicine that produces considerable side effects, and is used only in moderate to severe cases.
No, it is not recommended to be used in seasonal allergy or mild cases. Only on a doctor's consultation, Defoliz-6 Tablet 10's may be used in extreme cases of seasonal allergy.
Yes, Defoliz-6 Tablet 10's is a steroid medication. It's a corticosteroid, also known as a glucocorticoid.
Defoliz-6 Tablet 10's is less potent than Prednisone and is usually administered proportionately in higher doses.
No, Defoliz-6 Tablet 10's is not a painkiller. It is a steroid medication.
Yes, it can be used to treat kidney stones.
Swallow it whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.
It may be unsafe for some to use. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.
Yes, it is safe to use Defoliz-6 Tablet 10's if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.
Inadequate data available on the use of this drug in pregnant women to inform a drug-related risk. So, it should be used during pregnancy only if the benefit outweighs the risk to the fetus.
Common side effects of Defoliz-6 Tablet 10's may include nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhea and fast heartbeats. Most of these side effects of Defoliz-6 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Store in a cool and dry place away from sunlight. Please keep it away from pets and children.
Yes, weight gain is a common side effect of this medicine. It can increase your appetite and cause your body to hold onto extra water. Managing your diet and limiting salt intake can help control this. Talk to your doctor if weight gain becomes a concern.
You can take Defoliz-6 Tablet 10's with or without food. However, if you experience stomach upset, taking your dose with a meal or a glass of milk is highly recommended to protect your stomach lining.
Defoliz-6 Tablet 10's calms your immune system to reduce inflammation. While this is helpful for treating your condition, it also means your body may have a harder time fighting off infections. Wash your hands frequently and avoid contact with sick individuals.
Regular, inactive flu shots are generally safe, but you must avoid "live" vaccines while taking this medication. Always inform the healthcare provider administering the vaccine that you are taking Defoliz-6 Tablet 10's. Talk to your doctor to confirm.
Long-term use of corticosteroids like Defoliz-6 Tablet 10's can weaken your bones over time, increasing the risk of osteoporosis. Your doctor may suggest taking calcium and Vitamin D supplements to help protect your bones. Talk to your doctor for advice.
It is best to avoid or limit alcohol while taking this medicine. Both alcohol and oral steroids can irritate the stomach lining, and combining them increases your risk of developing stomach ulcers or bleeding.
You must tell your surgeon, anesthesiologist, and dentist that you are taking Defoliz-6 Tablet 10's. Because steroids affect how your body handles physical stress, your dosage may need to be adjusted temporarily before and after the procedure. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Center for Biotechnology Information (NCBI). Deflazacort Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.6287 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. MIMS Drug Reference Compendium. Deflazacort Monograph. Singapore: MIMS; 2025. [Accessed on 02 Jun. 2026] Check here
  4. MedlinePlus. A617024 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  5. Deflazacort [Prescribing Information]. 2017. [Accessed on 20 Feb. 2024] Check here
  6. Laura C. McAdam, Amanda L. Mayo, Benjamin A. Alman, and W. Douglas Biggar. The Canadian experience with long term deflazacort treatment in Duchenne muscular dystrophy. [Revised in May 2012] [Accessed on 15th June 2022] Check here
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 03 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

501-502, Aditraj Arcade, Opp. Titanium City Center, 100 Feet Rd, Satellite, Ahmedabad, Gujarat 380015
Other Info - DEF0554

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