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About Denu 60 mg Injection 1 ml
Denu 60 mg Injection 1 ml belongs to a group of medicines called RANK ligand inhibitors used to treat osteoporosis in postmenopausal women and men who have an increased risk of fracture. Denu 60 mg Injection 1 ml is also used to treat bone loss due to reduced testosterone level caused by surgery, due to the treatment with medicines such as glucocorticoids and in patients with prostate cancer. Denu 60 mg Injection 1 ml may also be used to reduce the risk of fractures in people with multiple myeloma, giant cell tumour of the bone, and to treat high calcium levels caused by cancer.
Denu 60 mg Injection 1 ml contains Denosumab, which works by blocking a receptor in the body that causes bone loss, thereby treating bone loss. Denu 60 mg Injection 1 ml treats giant cell tumour of bone (GCTB) by blocking certain receptors in the tumour cells, thereby slowing the growth of the tumour. Denu 60 mg Injection 1 ml helps treat high calcium levels by decreasing bone breakdown, as a breakdown of the bones releases calcium. Denu 60 mg Injection 1 ml makes the bones stronger and less likely to break.
Denu 60 mg Injection 1 ml will be administered by a healthcare professional; do not self-administer. Sometimes, you may experience common side effects such as bone/joint/muscle pain, arm/leg pain, abdominal discomfort, constipation, and painful/frequent urination. You should talk to your doctor if the side effects persist or worsen.
Denu 60 mg Injection 1 ml might cause jaw osteonecrosis; therefore, maintain good dental hygiene and receive regular dental check-ups whilst on treatment with Denu 60 mg Injection 1 ml. Avoid taking Denu 60 mg Injection 1 ml if you are pregnant. Consult your doctor before taking Denu 60 mg Injection 1 ml if you are breastfeeding. Denu 60 mg Injection 1 ml is not recommended for children below 18 years as safety and effectiveness have not been established. To rule out any interactions, keep your doctor informed about your health condition and medicines.
Uses of Denu 60 mg Injection 1 ml
Denu 60 mg Injection 1 ml used to treat osteoporosis, bone loss, giant cell tumour of the bone, and high calcium levels. The detailed uses of Denu 60 mg Injection 1 ml are as follows:

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Medicinal Benefits
Denu 60 mg Injection 1 ml belongs to a group of medicines called RANK ligand inhibitors used to treat osteoporosis in postmenopausal women and men who have an increased risk of fracture. Denu 60 mg Injection 1 ml is also used to treat bone loss due to reduced hormone levels caused by surgery or due to treatment with medicines in patients with prostate cancer. It is also used to treat bone loss occurring due to long-term treatment with glucocorticoids in patients who are at an increased risk of fractures. Denu 60 mg Injection 1 ml may also be used to reduce the risk of fractures in people with multiple myeloma, giant cell tumours of the bone and to treat high calcium levels caused by cancer. Denu 60 mg Injection 1 ml binds to a protein on RANK ligand on osteoclast (cells that cause bone breakdown) and inhibits their formation, functioning and survival. It decreases bone breakdown, increases bone density, and strengthens the bone. Denu 60 mg Injection 1 ml treats giant cell tumour of bone (GCTB) by blocking certain receptors in the tumour cells, thereby slowing the growth of the tumour. Denu 60 mg Injection 1 ml helps treat high calcium levels by decreasing bone breakdown, as the breakdown of the bones releases calcium. Denu 60 mg Injection 1 ml makes the bones stronger and less likely to break.
How Denu 60 mg Injection 1 ml Works
Storage
What if I have taken an overdose of Denu 60 mg Injection 1 ml
Drug Warnings
Do not take Denu 60 mg Injection 1 ml if you are allergic to any of its components or have hypocalcaemia (low levels of calcium in the blood). Inform your doctor if you have low levels of calcium, kidney dysfunction, liver problems, poor dental health, gum problems, weak immune system, hypoparathyroidism (decreased function of the parathyroid gland), malabsorption, latex allergy, undergone thyroid surgery, planned dental procedure, if you are taking glucocorticoids, or cannot take calcium and vitamin D supplements. Avoid taking Denu 60 mg Injection 1 ml if you are pregnant. Consult your doctor if you are breastfeeding. Denu 60 mg Injection 1 ml is not recommended for children below 18 years as safety and effectiveness have not been established.
Drug-Drug Interactions
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Alcohol
Caution
It is not known if alcohol interacts with Denu 60 mg Injection 1 ml, so please consult a doctor.
Pregnancy
Unsafe
Denu 60 mg Injection 1 ml is not recommended during pregnancy as it might cause foetal harm. If you are a woman of child-bearing potential, use effective contraception during the treatment with Denu 60 mg Injection 1 ml and for 5 months after discontinuation. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.
Breast Feeding
Caution
Consult your doctor if you are breastfeeding; your doctor will decide if breastfeeding mothers can take Denu 60 mg Injection 1 ml or not.
Driving
Safe if prescribed
Denu 60 mg Injection 1 ml generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.
Liver
Caution
Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Caution
Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Unsafe
Denu 60 mg Injection 1 ml is not recommended for children below 18 years as safety and effectiveness were not established.
Heart
Denu 60 mg Injection 1 ml should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving Denu 60 mg Injection 1 ml.
Geriatrics
Caution
Denu 60 mg Injection 1 ml should be administered with caution in older adults. Always seek medical advice before receiving it.
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