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More about the Product

Composition :

DOSULEPIN-50MG

Manufacturer/Marketer :

Mova Pharmaceutical Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Depnoc 50 mg Tablet

Depnoc 50 mg Tablet is a prescription medication primarily used to treat depression. It helps relieve persistent feelings of sadness, anxiety, and low mood by restoring the balance of certain natural chemicals in the brain. This medicine is also sometimes prescribed to help manage chronic nerve-related pain.

Dosulepin is a tricyclic antidepressant that is generally prescribed in selected situations, particularly when other antidepressant treatments are not suitable, have not provided adequate symptom relief, or are not well tolerated. Current treatment guidelines generally do not recommend dosulepin as a first-line treatment for depression because of its side-effect profile and increased risk in overdose. It is typically reserved for selected patients when other treatment options have not been effective or are not appropriate. 

To get the most benefit, you should take Depnoc 50 mg Tablet consistently at the same time every day, usually as a single dose before going to bed. You can take this medicine with or without food, but swallowing it with a glass of water is recommended. Incorporating positive lifestyle adjustments, such as maintaining a regular sleep schedule, eating a balanced diet, and engaging in light physical activity, can further support your recovery.

While taking Depnoc 50 mg Tablet , you may experience mild, common side effects such as dry mouth, drowsiness, or constipation. However, you must contact your doctor immediately if you experience serious symptoms like an irregular heartbeat, severe confusion, or any sudden changes in your mood, including thoughts of harming yourself.

Before starting this treatment, it is important to talk to your doctor if you have any pre-existing health conditions, particularly heart problems, glaucoma, epilepsy, or liver damage. Do not take this medicine if you have recently had a heart attack or if you suffer from severe heart block.

This medicine can interact with other substances, so you should avoid drinking alcohol, as it can dangerously increase sleepiness and dizziness. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor or pharmacist to discuss whether this treatment is safe for you.
 

Uses of Depnoc 50 mg Tablet

Depnoc 50 mg Tablet may be prescribed for the following conditions:

  • Depression: Depnoc 50 mg Tablet helps lift low mood, relieve feelings of worthlessness, and restore interest in daily activities by balancing brain chemicals.
  • Anxiety: This medicine may help reduce anxiety, tension, and nervousness that occur alongside depression by improving the balance of certain brain chemicals.
  • Chronic pain: In certain cases, Depnoc 50 mg Tablet is used to relieve ongoing nerve-related pain by altering how pain signals are transmitted to the brain.

Key Benefits

Depnoc 50 mg Tablet may provide the following benefits when used as prescribed:

  • Restores restful sleep: Because of its calming effects, Depnoc 50 mg Tablet is particularly beneficial for individuals whose depression or anxiety causes trouble sleeping, helping them get more restful night sleep.
  • Improves daily functioning: By gradually lifting your mood and reducing constant worry, this medicine helps you find the energy to resume your normal daily routines and hobbies.
  • Eases persistent pain: For those suffering from chronic discomfort, it provides physical relief by dampening constant pain signals, allowing for easier, more comfortable movement.
Side effects of Depnoc 50 mg Tablet
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
  • Maintain consistent habits, sleep patterns and food times to help maintain stability and reduce confusion.
  • Mindfulness techniques such as deep breathing or meditation help you stay focused and in the now.
  • Participate in cognitive therapy to enhance your ability to remember, focus and solve problems.
  • As directed by your physician, take your medications to help control underlying disorders like depression, anxiety or cognitive impairment.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

Directions for Use

Always take Depnoc 50 mg Tablet exactly as your doctor has instructed. Follow these steps for taking it safely:

  • Swallow the tablet or capsule whole with a full glass of water.
  • Do not crush, chew, or break the medicine, as this can affect how it is absorbed by your body.
  • Take this medicine at the same time every day, ideally in the evening or at bedtime, as it can make you feel sleepy.
  • You can take this medication with or without food.
  • Never change your dose or stop taking this medicine without first consulting your healthcare provider, even if you begin to feel better.

How Depnoc 50 mg Tablet Works

Dosulepin, the active ingredient in Depnoc 50 mg Tablet , belongs to a group of medicines known as tricyclic antidepressants. It primarily works by increasing the activity of norepinephrine and, to a lesser extent, serotonin, two natural chemical messengers involved in regulating mood, emotions, and pain perception. By preventing these chemical messengers from being reabsorbed too quickly by nerve cells, dosulepin keeps them active in the brain for longer periods. This helps improve communication between nerve cells, which may reduce symptoms of depression and alter the way pain signals are processed by the nervous system. Dosulepin also has antihistaminergic, anticholinergic, and alpha-adrenergic blocking effects. These actions contribute to its calming and sleep-promoting properties but may also cause side effects such as drowsiness, dry mouth, constipation, blurred vision, and dizziness.
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Alcohol

Unsafe

It is not recommended to take alcohol while taking Depnoc 50 mg Tablet to avoid unpleasant side effects.

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Pregnancy

Unsafe

It is advised not to take Depnoc 50 mg Tablet during pregnancy as it may pose a risk to the unborn baby. However, if you are already taking Depnoc 50 mg Tablet , please inform your doctor that you are pregnant.

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Breast Feeding

Caution

Depnoc 50 mg Tablet passes in very small amounts in breast milk. It has not been linked with any side effects. However, caution is advised while taking it. Please inform your doctor if you are breastfeeding.

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Driving

Unsafe

It is not recommended to drive after taking Depnoc 50 mg Tablet as it can make you feel drowsy.

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Liver

Caution

Caution is advised while taking Depnoc 50 mg Tablet if you suffer or have suffered from liver diseases.

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Kidney

Caution

Caution is advised while taking Depnoc 50 mg Tablet if you suffer or have suffered from kidney diseases.

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Children

Unsafe

Depnoc 50 mg Tablet is not recommended for children below 12 years of age.

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Heart

Unsafe

Depnoc 50 mg Tablet should be avoided in cardiac patients as it can lead to serious cardiavascular risks

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Geriatrics

Unsafe

Depnoc 50 mg Tablet should be avoided in geriatric patients as it can lead to serious side effects.

What if I have taken an overdose of Depnoc 50 mg Tablet

An overdose of Depnoc 50 mg Tablet may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Manage dry mouth: Drink water frequently throughout the day, chew sugar-free gum, or suck on sugar-free sweets to keep your mouth moist.
  • Prevent constipation: Eat a diet rich in dietary fibre, including plenty of fresh fruits, vegetables, and whole grains, and stay active with light daily exercise.
  • Avoid alcohol completely: Alcohol can severely interact with this medicine, causing extreme drowsiness, coordination issues, and a dangerous drop in blood pressure.
  • Stand up slowly: To prevent lightheadedness or fainting from a sudden drop in blood pressure, take your time when moving from a lying or sitting position to a standing position.

Have a query?

How Soon It Starts Working

The time required for Depnoc 50 mg Tablet to start to work: The time required for Depnoc 50 mg Tablet to show its action is unknown.

The time for which the effects of Depnoc 50 mg Tablet last: The duration of action for Depnoc 50 mg Tablet is unknown.

What if you forget to take Depnoc 50 mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Store Depnoc 50 mg Tablet in its original packaging to protect it from light and moisture. • Keep the medication at room temperature, ideally below 25°C

Drug Warnings

  • Do Not Stop Treatment Suddenly: Abruptly stopping Depnoc 50 mg Tablet may cause withdrawal symptoms such as nausea, headaches, anxiety, irritability, and sleep disturbances. Your doctor will advise you on gradually reducing the dose when treatment needs to be discontinued.
  • Be Careful When Driving or Operating Machinery: Depnoc 50 mg Tablet may cause drowsiness, dizziness, or blurred vision, particularly when treatment is first started. Avoid activities requiring alertness until you know how the medicine affects you.
  • Monitor Your Mental Health: Pay close attention to any sudden changes in mood, behaviour, or thoughts, especially during the first few weeks of treatment. Seek medical advice promptly if you experience worsening depression or thoughts of self-harm.
  • Inform Healthcare Professionals Before Procedures: Tell your dentist, surgeon, or anaesthesiologist that you are taking Depnoc 50 mg Tablet before undergoing any medical, surgical, or dental procedure.
  • Attend Regular Health Check-Ups: Your doctor may recommend monitoring of blood pressure, heart rate, and overall treatment response, particularly if you have a history of cardiovascular disease.
  • Take Overdose Risk Seriously: Depnoc 50 mg Tablet can be more dangerous in overdose than many newer antidepressants. Take the medicine exactly as prescribed and store it securely out of the reach of children and others.
  • Take Extra Care of Older Adults: Older adults may be more susceptible to dizziness, falls, confusion, drowsiness, and heart-related side effects while taking Depnoc 50 mg Tablet . Follow your doctor's instructions carefully and report any concerning symptoms promptly. 

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines:

  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine if you are taking, or have taken within the last 14 days, an MAOI antidepressant, as this can cause dangerously high blood pressure and body temperature.
  • Other antidepressants or pain medicines (like tramadol): Combining these can increase the risk of a rare but serious condition called serotonin syndrome, which causes muscle stiffness, sweating, and confusion.
  • Sleeping pills, sedatives, or strong painkillers: Taking these alongside this medicine can cause extreme sleepiness and slow down your breathing.
  • Medicines for irregular heartbeat: Taking these together may increase the risk of heart rhythm disturbances.


 

Drug-Food Interactions

  • Alcohol: Alcohol can significantly increase drowsiness, dizziness, impaired coordination, and the risk of accidents while taking Depnoc 50 mg Tablet . Avoid or limit alcohol consumption unless your doctor advises otherwise. 


Drug-Disease Interactions

Inform your doctor if you have any of the following conditions before taking Depnoc 50 mg Tablet :

  • Heart conditions: Avoid use if you have recently had a heart attack or have a known heart block, as this medicine can affect heart rhythms.
  • Epilepsy or history of seizures: This medicine can lower the seizure threshold, making fits more likely to occur.
  • Glaucoma (specifically narrow-angle glaucoma): This medicine can increase pressure inside the eye, potentially worsening your condition.
  • Enlarged prostate or urinary issues: Can make it more difficult to pass urine, worsening urinary retention.

Drug-Drug Interactions

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How does the drug interact with Depnoc 50 mg Tablet:
Coadministration of paroxetine and Depnoc 50 mg Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although taking Depnoc 50 mg Tablet and paroxetine together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, increased heart rate, fever, excessive sweating, blurred vision, muscle spasms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Depnoc 50 mg Tablet:
Coadministration of Amitriptyline and Depnoc 50 mg Tablet may increase the risk of irregular heartbeat. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although combining Amitriptyline with Depnoc 50 mg Tablet may result in an interaction, it can be used when a doctor recommends it. If you experience sudden dizziness or irregular heartbeats during therapy, contact your doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[PSYCHOTHERAPEUTICS]

FAQs

Depnoc 50 mg Tablet is used to treat depression and anxiety. It works by increasing the levels of chemical messengers which are responsible for stabilising and elevating mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety.

Depnoc 50 mg Tablet helps to elevate your mood levels. It helps you to get better sleep. It helps you to feel like yourself again.

It depends on your symptoms according to which your doctor will advise the dose and duration of Depnoc 50 mg Tablet . Please inform your doctor if you are planning to switch to any other antidepressant.

Depnoc 50 mg Tablet is not recommended to treat pain. Rarely, it is advised to treat nerve pain like fibromyalgia or to prevent migraine.

Some people may experience changes in appetite or weight while taking this medicine. Maintaining a balanced diet and staying active can help manage these effects. If you are concerned about weight gain or noticeable changes in your appetite, talk to your doctor.

Depnoc 50 mg Tablet may interact with several medications and impact their efficacy. So, taking any medications, including herbal or ayurvedic, other than those prescribed by the doctor, is not recommended.

No, it is not a muscle relaxant. Depnoc 50 mg Tablet is a tricyclic antidepressant medication used to treat depression.

Both Depnoc 50 mg Tablet and amitriptyline belong to the tricyclic antidepressant class used to treat symptoms of depression. However, do not replace the Depnoc 50 mg Tablet with amitriptyline unless recommended by the doctor.

Depnoc 50 mg Tablet and doxepin belong to tricyclic antidepressant class medications used to treat symptoms of depression. However, they may have different mechanisms of action. However, do not replace the Depnoc 50 mg Tablet with doxepin unless recommended by the doctor.

You may take several weeks or longer to experience the full effect of Depnoc 50 mg Tablet . Even if you are feeling good, continue to take Depnoc 50 mg Tablet . Do not discontinue taking Depnoc 50 mg Tablet without consulting your doctor. Before quitting, your doctor will most likely recommend that you gradually reduce your dose.

Depnoc 50 mg Tablet is associated with high mortality (death rate) in overdose. There is a low margin of safety between the maximum therapeutic dose and potentially fatal doses. So, you should strictly follow the dose and duration of Depnoc 50 mg Tablet as directed by the physician. Do not overdose at any cost. If you feel you or someone overdosed or experience any severe adverse events with Depnoc 50 mg Tablet , consult the doctor or go to the emergency room nearest hospital.

Caution should be exercised. The risk or severity of CNS depression can be increased when Diazepam is combined with Depnoc 50 mg Tablet .

No. Depnoc 50 mg Tablet is not intended to treat trigeminal neuralgia (sudden, severe facial pain. It's commonly described as a sudden shooting pain or as an electric shock to the jaw, teeth, or gums.).

No. $ name is not intended to treat burning mouth syndrome (a painful condition often described as a burning, scalding, or tingling feeling in the mouth that may occur every day for months).

Yes, Depnoc 50 mg Tablet is intended to treat depression. However, it is a prescription medication and should be taken only if the doctor prescribes it to you.

No. Depnoc 50 mg Tablet is not intended to treat IBS (irritable bowel syndrome). Depnoc 50 mg Tablet is a tricyclic antidepressant medication used to treat depression.

It is not intended for insomnia with depression alone. However, your doctor may suggest Depnoc 50 mg Tablet to treat insomnia with depression in some cases. Please consult your doctor for personalized guidance.

Depnoc 50 mg Tablet can change the way your nerves receive pain signals. This can help with some kinds of nerve pain, including fibromyalgia. However, it should only be taken as prescribed by the doctor.

Depnoc 50 mg Tablet is sometimes used to treat some types of nerve pain, such as fibromyalgia, or to prevent migraine. But it's not recommended or officially approved for pain relief.

Depnoc 50 mg Tablet works by increasing levels of a chemical called serotonin in the brain. This can improve your mood.

You may begin to notice some improvements in your sleep patterns within the first week or two. However, it usually takes between 4 to 6 weeks of consistent daily use to feel the full antidepressant effects. Do not stop taking it if you do not feel better immediately. Talk to your doctor if you do not notice any improvement after a few weeks.

No, Depnoc 50 mg Tablet is not recommended for everyone. It can be harmful to some people and is very dangerous if you take too much. Take personalized guidance from your doctor by letting them know your medical condition and the medications you are taking.

Depnoc 50 mg Tablet is not addictive, but you may get withdrawal symptoms when you stop taking it, especially if you stop taking it suddenly. Withdrawal symptoms of Depnoc 50 mg Tablet may include giddiness, headache, insomnia, irritability, increased sweating, nausea, panic-anxiety and restlessness.

Some people feel sleepy while they're taking Depnoc 50 mg Tablet . If this happens to you, do not drive, cycle or use machinery or tools until you feel better.

No, you should avoid drinking alcohol while taking this medicine. Alcohol significantly increases the drowsiness and dizziness caused by the medication, which can impair your coordination and increase the risk of accidents. Talk to your doctor if you find it difficult to avoid alcohol.

Limited research is available on Depnoc 50 mg Tablet in pregnant women. So, talk to your doctor if you are taking Depnoc 50 mg Tablet and are planning a pregnancy or becoming pregnant. The doctor will help you weigh the risks and benefits to decide on the best treatment for you and your baby. Your mental health must be well treated during pregnancy, as it can affect you and your baby's wellbeing.

No clear evidence suggests that taking Depnoc 50 mg Tablet will reduce fertility in either men or women. However, speak to a healthcare professional before taking it about its potential benefits and risks.

No, Depnoc 50 mg Tablet is not recommended for children below 12 years of age. Please seek medical attention if you observe any depression symptoms in your kid.

Symptoms of overdose may include cold body temperature, coma (loss of consciousness for a period of time), feeling agitated, confused, or drowsy, fever, hallucination (seeing things or hearing voices that do not exist), irregular heartbeat, increase in pupil size, muscle stiffness, seizures, trouble concentrating and vomiting.

Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Yes, drowsiness is a very common side effect of this medicine, especially when you first start taking it. Because of this, it is usually prescribed to be taken once daily at bedtime. Avoid driving or performing tasks that require focus if you feel drowsy during the day. Talk to your doctor if the sleepiness becomes unmanageable.

No, you should never stop taking this medicine suddenly, even if you feel completely better. Stopping abruptly can cause withdrawal symptoms like nausea, headache, and anxiety, and may cause your depression to return. Your doctor will guide you on how to stop safely by gradually decreasing the dose. Talk to your doctor before making any changes.

This medicine is generally not recommended during pregnancy or breastfeeding unless your doctor decides that the benefits outweigh the potential risks to the baby. If you plan to become pregnant or are currently breastfeeding, talk to your doctor or pharmacist to discuss safe treatment options.

Dry mouth is a common and usually harmless side effect. You can manage it by sipping cool water frequently, chewing sugar-free gum, or sucking on sugar-free hard sweets. If the dryness is severe, persists for a long time, or affects your dental health, talk to your doctor.

Yes, this medicine can affect your heart rate and rhythm, particularly if you have a pre-existing heart condition or take a high dose. Your doctor may perform heart checks before and during your treatment. If you experience a fast, irregular, or pounding heartbeat, seek medical help immediately and talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

F-11, 2nd Main Road, Anna Nagar East, Chennai - 600 102.
Other Info - DEP0047
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