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compositionComposition:SERTRALINE-50MG
prescription
Prescription Medicine
info
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Deptralin 50 mg Tablet 14's is used in the treatment of depression, post-traumatic stress disorder (PTSD), social anxiety disorder, panic disorder and obsessive-compulsive disorder (OCD). It contains Sertraline, which increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic. Some people may experience side effects such as drowsiness, dizziness, insomnia (difficulty in sleeping), dry mouth, nausea, headache, diarrhoea, tiredness or ejaculation failure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SERTRALINE-50MG

Manufacturer/Marketer :

BMP Life Science

Consume Type :

Oral

Return Policy :

Not Returnable

About Deptralin 50 mg Tablet 14's

Deptralin 50 mg Tablet 14's is an oral prescription medication primarily used to treat depression, panic attacks, obsessive-compulsive disorder, and post-traumatic stress disorder. It helps restore the natural chemical balance in your brain to improve your mood, sleep, appetite, and energy levels. This medicine belongs to a class of drugs widely prescribed by mental health professionals to help manage ongoing emotional distress.

To achieve the best results, you should take Deptralin 50 mg Tablet 14's consistently at the same time every day, either with or without food. Establishing a regular daily routine helps maintain a steady level of the medication in your body. Combining this treatment with healthy daily habits, such as regular light exercise and structured sleep routines, can significantly support your progress.

While taking Deptralin 50 mg Tablet 14's, some people may experience mild, temporary side effects like nausea, dry mouth, or trouble sleeping, which usually fade within a few weeks. However, you must contact your doctor immediately if you notice any severe changes in your mood, severe dizziness, or signs of an allergic reaction. Your healthcare provider is your best resource for managing any unexpected physical or emotional changes.

Talk to your doctor before starting Deptralin 50 mg Tablet 14's if you have a history of seizures, liver damage, heart problems, or bipolar disorder. Do not take this if you are currently taking monoamine oxidase inhibitors (MAOIs) or pimozide, as combining these can lead to dangerous, life-threatening reactions. Only a qualified healthcare professional can determine if this medication is safe for your specific medical history.

This medicine can interact with alcohol, which can significantly worsen drowsiness and coordination, so it is highly recommended to avoid alcoholic drinks during treatment. You should also consult your doctor if you are pregnant, planning to become pregnant, breastfeeding, or if you are an older adult, as these situations require specialized medical guidance.

Uses of Deptralin 50 mg Tablet 14's

Deptralin 50 mg Tablet 14's is used in the treatment of depression, anxiety, and certain mood-related disorders. The detailed uses of Deptralin 50 mg Tablet 14's are as follows:

  • Major Depressive Disorder: It helps relieve persistent feelings of sadness, restores interest in daily activities, and improves overall energy levels.
  • Obsessive-Compulsive Disorder (OCD): It assists in reducing persistent, unwanted thoughts and the urge to perform repetitive, compulsive actions.
  • Panic Disorder: It helps decrease the frequency and intensity of sudden, unexpected panic attacks and reduces the constant fear of future attacks.
  • Post-Traumatic Stress Disorder (PTSD): It helps alleviate severe anxiety, intrusive memories, and hyper-awareness triggered by traumatic events.
  • Social Anxiety Disorder: It reduces extreme self-consciousness, fear, and avoidance of social situations, helping you feel more comfortable around others.
  • Premenstrual Dysphoric Disorder (PMDD): It helps stabilize severe mood swings, irritability, and physical discomfort associated with the premenstrual cycle.

Key Benefits

Deptralin 50 mg Tablet 14's helps improve emotional well-being by reducing symptoms of depression, anxiety, and related mental health conditions. By supporting a more balanced mood, it can help you feel more in control of your thoughts, emotions, and daily activities. Benefits may include:

  • Helps reduce feelings of depression, sadness, and hopelessness.
  • Relieves anxiety, excessive worry, and nervousness.
  • Helps manage panic symptoms and improves confidence in social situations.
  • Reduces repetitive thoughts and compulsive behaviours associated with certain anxiety disorders.
  • Supports healthier sleep patterns, appetite, and overall emotional balance.
  • Improves daily functioning, relationships, and overall quality of life.

Directions for Use

  •  Swallow the tablet whole with a full glass of water. Do not chew, crush, or break the tablet, as this can affect how the medicine is absorbed into your system.
  • You may take this medication with or without food.
  • Take your dose at the same time every day to maintain a consistent amount of the medicine in your body.
  • Always follow your doctor's exact instructions regarding your dose and schedule. Never stop taking this medication suddenly without consulting your healthcare provider first.

How Deptralin 50 mg Tablet 14's Works

Deptralin 50 mg Tablet 14's works by targeting specific chemical messengers in the brain, with a primary focus on a chemical called serotonin. Serotonin plays a critical role in regulating your mood, sleep, emotions, and overall sense of well-being. In individuals experiencing depression or anxiety, active serotonin levels in the brain may be lower than normal. This medication acts as a selective serotonin reuptake inhibitor (SSRI). It works by blocking brain cells from reabsorbing serotonin after it is released. By preventing this reabsorption, more serotonin remains active in the gaps between brain cells, which strengthens communication between nerves and helps restore emotional balance.
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Alcohol

Unsafe

Avoid consumption of alcohol with Deptralin 50 mg Tablet 14's as it may increase the risk of drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Deptralin 50 mg Tablet 14's is a Category C pregnancy drug and is not recommended for use during pregnancy especially in the last 3 months as it may cause a serious condition in the baby such as persistent pulmonary hypertension of the newborn (PPHN) which causes the baby to appear bluish and makes breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Deptralin 50 mg Tablet 14's may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Deptralin 50 mg Tablet 14's is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Unsafe

Deptralin 50 mg Tablet 14's may cause dizziness, drowsiness or impair thinking. Therefore, avoid driving if you experience any of these symptoms after taking Deptralin 50 mg Tablet 14's.

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Liver

Caution

Take Deptralin 50 mg Tablet 14's with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Deptralin 50 mg Tablet 14's in patients with kidney problems, please consult a doctor.

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Children

Consult your doctor

Deptralin 50 mg Tablet 14's may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years. Deptralin 50 mg Tablet 14's is not recommended to treat any other disorders in children below 18 years of age.

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Heart

Safe if prescribed

Deptralin 50 mg Tablet 14's is safe for use in heart patients if prescribed by the physician.

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Geriatrics

Safe if prescribed

Deptralin 50 mg Tablet 14's can be safely given in elderly patients if recommended by the physician.

What if I have taken an overdose of Deptralin 50 mg Tablet 14's

If you or someone else takes more than the prescribed dose of this medicine, seek immediate medical attention or contact a poison control center right away. Symptoms of an overdose can include extreme sleepiness, severe nausea, vomiting, a rapid heart rate, or shaking.

Diet & Lifestyle Advise

  • Limit or avoid alcohol: Drinking alcohol while taking this medicine can severely increase drowsiness, impair your coordination, and reduce the effectiveness of your treatment.
  • Stay well-hydrated: Drink plenty of water throughout the day, as some medications in this class can cause mild dehydration or lower sodium levels, particularly in older adults.
  • Maintain a consistent sleep routine: Go to bed and wake up at the same times every day, and limit caffeine intake in the afternoon and evening to support better sleep quality.
  • Incorporate regular light exercise: Activities like walking, swimming, or gentle yoga can help boost natural endorphins and work alongside your medication to improve mood.
  • Eat balanced meals: Eating small, regular meals can help manage initial, mild side effects such as nausea or changes in appetite.
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Have a query?

How Soon It Starts Working

  • The time required for Deptralin 50 mg Tablet 14's to start to work: The time required for Deptralin 50 mg Tablet 14's to show its action is unknown.
  • The time for which the effects of Deptralin 50 mg Tablet 14's last: The duration of action for Deptralin 50 mg Tablet 14's is unknown.

What if you forget to take Deptralin 50 mg Tablet 14's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular timing. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid driving if you feel dizzy: Do not drive, operate machinery, or perform tasks requiring sharp mental focus until you know how this medication affects you.
  • Check liquid clarity: If using the liquid concentrate form, make sure the solution is clear and colorless before mixing and taking it. Do not use it if it is cloudy or changed in color.
  • Monitor for mood and behavior changes: Deptralin 50 mg Tablet 14's may increase the risk of suicidal thoughts, self-harming behavior, or unusual changes in mood, particularly in children, adolescents, and young adults during the first few weeks of treatment or after a dose adjustment.
  • Ensure close supervision in younger patients: Children and adolescents taking Deptralin 50 mg Tablet 14's should be monitored regularly by a specialist to assess treatment response and watch for any behavioral or emotional changes.
  • Do not stop treatment abruptly: Do not stop taking Deptralin 50 mg Tablet 14's suddenly, as this may cause withdrawal symptoms such as dizziness, headache, nausea, anxiety, sleep disturbances, or tingling sensations. Your doctor may gradually reduce the dose before stopping treatment.
  • Contact your doctor if symptoms persist or worsen: Speak with your healthcare provider if your symptoms do not improve, become worse, or if side effects interfere with your daily activities.
  • Seek urgent medical attention for serious reactions: Get immediate medical help if you experience thoughts of self-harm, symptoms of serotonin syndrome, severe allergic reactions, unusual bleeding, seizures, or loss of consciousness.

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Drug-Drug Interactions

  • Monoamine Oxidase Inhibitors (MAOIs): Taking these together can cause a dangerous, life-threatening condition called serotonin syndrome. Do not take Deptralin 50 mg Tablet 14's within 14 days of using an MAOI.
  • Blood thinners (e.g., warfarin): Taking these medicines alongside Deptralin 50 mg Tablet 14's may increase the risk of bruising, bleeding, or internal bleeding.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., aspirin, ibuprofen, naproxen): Combining these with Deptralin 50 mg Tablet 14's may increase the risk of stomach bleeding, ulcers, and other bleeding-related complications.
  • Triptans and other SSRIs: Taking this with other medicines that raise serotonin levels (like certain migraine drugs or other antidepressants) increases the risk of severe serotonin-related side effects.

Drug-Food Interactions

  • Grapefruit juice: Avoid consuming large quantities of grapefruit juice, as it can interfere with how your body breaks down this medication, potentially raising drug levels in your blood.
  • Alcohol: Avoid alcoholic beverages completely, as alcohol can dangerously increase the sedative effects of this medicine.

Drug-Disease Interactions

  • Liver damage: If you have liver problems, your body may process this medicine more slowly, which may require your doctor to adjust your dose.
  • Seizure disorders: This medicine should be used with extreme caution if you have a history of epilepsy, as it may increase the risk of seizures.
  • Bipolar disorder: This medication can sometimes trigger manic episodes in individuals who have undiagnosed bipolar disorder.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

Deptralin 50 mg Tablet 14's used in the treatment of Depression, Post-traumatic stress disorder (PTSD), Social anxiety disorder, Panic disorder, and Obsessive-compulsive disorder (OCD).
Yes, Deptralin 50 mg Tablet 14's may be used to treat a panic disorder by reducing fear. However, please consult a doctor before using the Deptralin 50 mg Tablet 14's.
No, you are not recommended to take Deptralin 50 mg Tablet 14's with opioids as co-administration of these medicines may cause adverse effects such as hallucinations, increased muscle tension, excessive sweating, fever, anxiety, involuntary, rhythmic contractions of muscles, including the muscles that control eye movement, tremor or even coma. However, before using Deptralin 50 mg Tablet 14's with any other medicines, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.
Yes, Deptralin 50 mg Tablet 14's may cause self-harming or suicidal thoughts, especially in patients aged less than 25 years or who have a history of self-harming thoughts. Therefore, please consult a doctor immediately if you experience any such thoughts while taking Deptralin 50 mg Tablet 14's.
The duration of treatment varies from person to person. Many individuals continue treatment for at least 6 to 12 months after their symptoms improve. Some people may require longer treatment to prevent symptoms from returning. Your doctor will determine the most appropriate treatment duration based on your condition and progress.
Deptralin 50 mg Tablet 14's may affect male fertility as it may reduce sperm quality. Therefore, please consult a doctor if you are planning to father a child.
Deptralin 50 mg Tablet 14's should be used with caution in diabetic patients as it may alter blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Deptralin 50 mg Tablet 14's, especially if you have diabetes, and the dose of diabetic medicines may be adjusted appropriately by your doctor.
Deptralin 50 mg Tablet 14's contains Sertraline, which inhibits the reabsorption of released serotonin back into the nerve cells. Thus, it increases the serotonin (chemical messenger) activity in the brain that regulates mood, behaviour and emotions. Thereby, Deptralin 50 mg Tablet 14's helps in relieving depression, lightening the mood and relieving anxiety symptoms such as fear and panic.
The side effects of Deptralin 50 mg Tablet 14's include nausea, headache, diarrhoea, tiredness, drowsiness, dizziness and insomnia (difficulty sleeping). If these side effects persist or worsen, please consult your doctor.
You are recommended to take Deptralin 50 mg Tablet 14's for as long as it is prescribed by your doctor, which may be for several months. Do not stop taking Deptralin 50 mg Tablet 14's before the advised time as it may cause depression to recur.
Take Deptralin 50 mg Tablet 14's as advised by your doctor. It can be taken with or without food at any time of the day and is usually taken once a day. Take it as per your convenience but preferably at the same time every day. Some people should take it in the morning who have sleep difficulty after taking Deptralin 50 mg Tablet 14's. Whereas, some take it at night to minimize the side effects of vomiting and nausea.
Yes, mild drowsiness or fatigue is a common side effect, especially during the first few weeks of starting the medication. If it makes you feel sleepy during the day, your doctor may suggest taking your daily dose in the evening. Talk to your doctor to find the best dosing schedule.
Deptralin 50 mg Tablet 14's increases the serotonin levels which is an important chemical and a neurotransmitter. This helps to improve and regulate mood, resulting in an improvement in the anxiety symptoms.
No, you should not stop taking this medication on your own, even if you feel fine. Stopping suddenly can cause withdrawal symptoms like dizziness, irritability, and headache. Your doctor will help you gradually decrease your dose when it is safe to stop. Talk to your doctor before making any changes.
The withdrawal symptoms of Deptralin 50 mg Tablet 14's include numbness or tingling in the hands or feet, dizziness, nausea, trouble sleeping, headaches, feeling agitated or anxious, and shaking. However, these symptoms are usually mild to moderate and disappear 1-2 weeks after stopping Deptralin 50 mg Tablet 14's.
The symptoms of Deptralin 50 mg Tablet 14's overdose include fever, nausea, vomiting, dizziness, confusion, shakiness, and a rapid heartbeat. Whereas, serious side effects include heart problems, fainting, delirium, and changes in blood pressure. If you experience such symptoms, contact your doctor immediately.
Weight changes can vary; some people experience a mild decrease in appetite or temporary weight loss when starting the medicine due to mild nausea, while others may experience weight gain over long-term use. Talk to your doctor if you have concerns about weight changes during your treatment.
The decision to use Deptralin 50 mg Tablet 14's during pregnancy requires careful consideration of both the benefits and potential risks. Untreated depression, anxiety, and other mental health conditions can also affect the health of both the mother and baby. Your doctor will carefully assess your individual situation and discuss the most appropriate treatment approach. If you are pregnant, planning a pregnancy, or become pregnant while taking Deptralin 50 mg Tablet 14's, contact your doctor as soon as possible.
Moderate caffeine intake is generally safe, but because caffeine can worsen anxiety symptoms and disrupt sleep, it is best to limit your intake, especially in the afternoon. Talk to your doctor if you experience increased jitteriness or trouble sleeping.
You should use caution when taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, as they can increase the risk of stomach bleeding when combined with this medicine. Acetaminophen is generally a safer option for pain relief. Talk to your doctor or pharmacist for advice.
Sexual side effects, such as a decreased sex drive or difficulty reaching orgasm, are recognized side effects of this class of medication. These symptoms often persist during treatment but can be managed by adjusting your dose or exploring other treatment options. Talk to your doctor to find a comfortable solution.
Stopping Deptralin 50 mg Tablet 14's abruptly can cause discontinuation symptoms such as dizziness, nausea, headache, anxiety, sleep disturbances, vivid dreams, irritability, and tingling sensations. Your doctor will usually recommend gradually reducing the dose over time to help minimize these effects.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.10586 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Sertraline Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Sertraline - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Singh HK, Saadabadi A Sertraline. [Updated 2023 Feb 13]. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023Check here
  5. Kornstein SG, Pearlstein TB, Fayyad R, Farfel GM, Gillespie JA Kornstein SG, Pearlstein TB, Fayyad R, Farfel GM, Gillespie JA. 2006. [Accessed on 06 Aug. 2023]Check here
  6. Sertraline Hydrochloride [Prescribing Information]. 2023. [Accessed on 06 Aug. 2023]Check here
  7. emc Sertraline. [[Accessed on 26.Aug].2019]Check here

Country of origin

India

Manufacturer/Marketer address

Shop No. 37 Csc - 7, Dda Market, Sector - 16, Rohini, New Delhi - 110089
Other Info - DEP0392
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