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compositionComposition:DEXAMETHASONE-4MG
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Prescription Medicine
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Dexalab Injection contains dexamethasone, which is used to treat severe allergic conditions, collagen diseases, pulmonary disorders, blood disorders, rheumatic diseases, skin diseases, gastrointestinal disorders, etc. This medicine belongs to the corticosteroid class, which works by inhibiting the production of certain chemical messengers in the body that cause inflammation. Thus, it helps reduce swelling, redness, and itching.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DEXAMETHASONE-4MG

Manufacturer/Marketer :

Laborate Pharmaceuticals India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Dexalab Injection

Dexalab Injection is a sterile steroid injection used to treat severe swelling, intense allergic reactions, and active immune system disorders. It helps manage sudden flare-ups of arthritis, severe skin conditions, and breathing difficulties like acute asthma. Your doctor may also inject this medicine to treat certain cancers or hormone imbalances.

Because this is an injection, a healthcare provider will usually give it on a strict schedule, but you must receive it consistently to keep your symptoms under control. While food does not affect how this injection works, eating a low-salt diet and getting regular low-impact exercise can help reduce the fluid retention and joint pressure caused by the treatment.

Common side effects include mild pain at the injection site, trouble sleeping, and an increased appetite. However, you must talk to your doctor immediately if you experience serious side effects, such as a fever, blurred vision, severe muscle weakness, or sudden swelling in your ankles.

Tell your doctor about your health history before starting this treatment, especially if you have high blood pressure, diabetes, or a history of stomach ulcers. Do not take this if you have a widespread fungal infection or are allergic to any ingredients in the injection.

This medicine can interact with blood thinners and water pills, which increases your risk of bleeding or dangerous drops in potassium. You should also talk to your doctor before using this medicine if you are pregnant, breastfeeding, smoking, or are an older adult, as these factors can increase your risk of complications.

Uses of Dexalab Injection

Dexalab Injection may be used to help manage the following conditions:

  • Severe allergic reactions: It rapidly reduces swelling, hives, and airway blockage during life-threatening allergic emergencies.
  • Inflammatory joint conditions: It is injected directly into joints to relieve intense pain, swelling, and stiffness caused by arthritis or gout.
  • Asthma and breathing disorders: It helps open up inflamed airways during severe flare-ups, making it easier to breathe.
  • Skin and eye inflammation: It controls severe swelling and redness caused by autoimmune diseases affecting the skin, eyes, or kidneys.
  • Swelling of the brain: It helps lower dangerous pressure in the skull caused by brain tumors or head injuries.

Key Benefits

Dexalab Injection injection is a corticosteroid used to treat severe inflammation, allergic reactions, autoimmune disorders, and certain medical emergencies. It works by reducing inflammation and suppressing an overactive immune response, helping relieve symptoms and prevent complications.

  • Rapidly Reduces Inflammation: Helps relieve swelling, redness, pain, and inflammation associated with various inflammatory and autoimmune conditions.
  • Provides Fast Relief in Severe Allergic Reactions: Helps reduce severe allergic symptoms and is often used as part of emergency treatment for serious allergic reactions.
  • Supports Breathing in Respiratory Conditions: Helps reduce airway inflammation in conditions such as severe asthma or croup, improving breathing when prescribed.
  • Helps Manage Autoimmune Disorders: Suppresses excessive immune activity, helping control symptoms in conditions where the immune system attacks healthy tissues.
  • Improves Recovery and Physical Function: By reducing inflammation and swelling, it helps relieve discomfort, improve mobility, and support recovery from acute illness or injury.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Dexalab Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Dexalab Injection Works

Dexalab Injection contains dexamethasone. It belongs to a class of medicines known as corticosteroids, which act like the natural hormones produced by your adrenal glands. When injected, it works by blocking the release of specific chemicals in your body that trigger swelling, redness, and pain. Additionally, Dexalab Injection calms an overactive immune system. In autoimmune conditions, the body's defence system mistakenly attacks healthy tissues; this medicine helps suppress this abnormal immune response, protecting your organs and tissues from further damage.
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Alcohol

Caution

It is unknown whether alcohol interacts with Dexalab Injection. Please consult your doctor.

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Pregnancy

Caution

If you are pregnant, inform your doctor. Your doctor will then decide if the Dexalab Injection is suitable for you. Your doctor may prescribe this medicine only if the benefits outweigh the risks.

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Breast Feeding

Caution

Inform your doctor if you are a nursing mother. The doctor will then decide if the injection is suitable for you. Your doctor may prescribe this medicine only if the benefits outweigh the risks.

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Driving

Caution

Dexalab Injection may cause a reduction in mental awareness; thus, avoid operating machinery or driving.

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Liver

Caution

Inform your doctor before receiving the Dexalab Injection if you have a history of or ongoing liver disease. Your doctor will adjust the dose of this medicine if required based on your condition.

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Kidney

Caution

Inform your doctor before receiving the Dexalab Injection if you have a history of or ongoing kidney disease. Your doctor may carry out extra checks while you are taking this medicine.

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Children

Caution

Dexalab Injection may affect children's growth. Therefore, your doctor may check the child's growth regularly while using the Dexalab Injection.

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Heart

Caution

Dexalab Injection may be used in heart patients, but it requires caution due to potential risks like fluid retention, arrhythmias, and elevated blood pressure. Always consult your doctor, as benefits and risks vary based on your specific cardiac condition.

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Geriatrics

Caution

Geriatric patients can receive Dexalab Injection, but it may be more prone to side effects like fluid retention, high blood pressure, or mood changes. Close monitoring and dose adjustments are advised during treatment.

What if I have taken an overdose of Dexalab Injection

Because this medicine is typically injected by a healthcare provider, an overdose is highly unlikely. However, if you receive too much of this medicine or experience severe symptoms after an injection, seek immediate medical attention or call a poison control centre right away.

Diet & Lifestyle Advise

  • Limit your salt intake: This medication can cause your body to hold onto sodium and water, leading to swelling. Avoid processed foods and do not add extra salt to your meals.
  • Eat potassium-rich foods: Steroid treatments can lower your potassium levels. Incorporate foods like bananas, spinach, and sweet potatoes into your diet.
  • Focus on calcium and vitamin D: Long-term steroid use can weaken bones. Ensure you get enough calcium and vitamin D through dairy products, leafy greens, or supplements recommended by your doctor.
  • Monitor your blood sugar: If you have diabetes, keep a close watch on your blood sugar levels, as this injection can cause them to rise.
  • Protect your joints: If you received an injection directly into a joint, rest that joint for at least 24 to 48 hours to allow the medicine to work and prevent injury.
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Have a query?

How Soon It Starts Working

The time required for Dexalab Injection to start to work: The onset time of Dexalab Injection has not been clinically established. The time for which the effects of Dexalab Injection last: The duration of Dexalab Injection’s effect is clinically not established.

What if you forget to take Dexalab Injection

If you miss an appointment for your injection, contact your doctor or clinic right away to reschedule. If you are injecting this medicine at home and forget a dose, inject it as soon as you remember. However, if it is almost time for your next scheduled injection, skip the missed dose and return to your regular schedule. Do not inject a double dose to make up for a missed one.

Storage

• Store Dexalab Injection injection vials at room temperature, between 20°C and 25°C (68°F and 77°F).

Drug Warnings

  • Inspect the liquid before use: Always check the vial before injecting. The liquid should be clear and colourless; do not use it if it is cloudy, discoloured, or contains visible particles.
  • Rotate your injection sites: If you require multiple injections, change the location of the injection each time to reduce the risk of skin thinning, scarring, or pain.
  • Never reuse needles: Use a sterile needle and syringe for every single injection to prevent serious infections.
  • Avoid live vaccines: Talk to your doctor before getting any immunisations, as this medicine suppresses your immune system and makes live vaccines unsafe.
  • Do not stop suddenly: Stopping this medication abruptly after long-term use can cause severe fatigue, dizziness, and low blood pressure. Your doctor will help you by gradually adjusting dose levels down safely.
  • Watch for signs of infection: Since this medicine dampens your immune response, you may catch infections more easily or experience delayed healing. Avoid contact with people who are sick.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (like warfarin): Dexalab Injection can change how these medicines work, increasing your risk of bleeding or blood clots.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs like ibuprofen): Combining these with this injection can significantly increase your risk of stomach ulcers and bleeding.
  • Diabetes medicines: This injection can raise your blood sugar, reducing the effectiveness of insulin or oral diabetes drugs.
  • Water pills (diuretics): Taking these together can cause your potassium levels to drop dangerously low, affecting your heart rhythm.
DexamethasoneRilpivirine
Critical

Drug-Drug Interactions

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DexamethasoneRilpivirine
Critical
How does the drug interact with Dexalab Injection 30 ml:
When Rilpivirine is taken with Dexalab Injection 30 ml, may significantly reduce the blood levels of Rilpivirine.

How to manage the interaction:
Co-administration of Rilpivirine and Dexalab Injection 30 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexalab Injection 30 ml:
When Regorafenib is taken with Dexalab Injection 30 ml, may significantly reduce the blood levels of Regorafenib.

How to manage the interaction:
Co-administration of Regorafenib and Dexalab Injection 30 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexalab Injection 30 ml:
Co-administration of Desmopressin with Dexalab Injection 30 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Dexalab Injection 30 ml and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexalab Injection 30 ml:
When Dexalab Injection 30 ml is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine and Dexalab Injection 30 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexalab Injection 30 ml:
Taking Dexalab Injection 30 ml with Leflunomide may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Dexalab Injection 30 ml can be taken with Leflunomide if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dexalab Injection 30 ml:
Taking Cladribine with Dexalab Injection 30 ml can increase the chances of serious infections.

How to manage the interaction:
Although there is a possible interaction between Cladribine and Dexalab Injection 30 ml, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexalab Injection 30 ml:
Taking Dexalab Injection 30 ml may reduce the blood levels of Axitinib, making the medication less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction, Dexalab Injection 30 ml can be taken with axitinib if prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dexalab Injection 30 ml:
Taking Dexalab Injection 30 ml may reduce the blood levels of Dasatinib, making the medication less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction, Dexalab Injection 30 ml can be taken with Dasatinib if prescribed by the doctor. In case of any unusual side effects, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dexalab Injection 30 ml:
Taking fentanyl with Dexalab Injection 30 ml may reduce the blood levels of fentanyl, which may make the medication less effective in treating your pain.

How to manage the interaction:
Although there is an interaction between diphenhydramine and ketamine, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience watery eyes, excessive sweating, body aches, abdominal cramping, vomiting, diarrhea. Do not discontinue using any medications without consulting a doctor.
DexamethasoneToremifene
Severe
How does the drug interact with Dexalab Injection 30 ml:
When Toremifene is taken with Dexalab Injection 30 ml, may reduce the effectiveness of Toremifene.

How to manage the interaction:
There may be a possibility of interaction between Dexalab Injection 30 ml and Toremifene, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Salt and sodium: Eating high-sodium foods can worsen fluid retention, swelling, and high blood pressure caused by the injection.
DEXAMETHASONE-4MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEXAMETHASONE-4MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking Dexalab Injection 30 ml with Caffeine may increase the side effects of Dexalab Injection 30 ml. Avoid consuming Caffeine while taking Dexalab Injection 30 ml.

Habit Forming

No

Therapeutic Class

[CORTICOSTEROIDS]

FAQs

Dexalab Injection is used in conditions like severe allergy, collagen, pulmonary, blood, rheumatic, skin, gastrointestinal, oedema, eye, neoplastic, and endocrine disorders.
Dexalab Injection contains dexamethasone, a steroid with both anti-inflammatory and immunosuppressant activity. Anti-inflammatory activity relieves the symptoms of inflammatory conditions such as redness, swelling, and tenderness caused by various medical conditions. On the other side, immunosuppressant activity helps to calm your immune system. As a result, it can aid in autoimmune diseases such as rheumatoid arthritis, in which your immune system erroneously destroys your tissues.
If you are about to be vaccinated, especially if it is a live vaccine, inform your doctor that you are taking Dexalab Injection because it is not recommended to take Dexalab Injection and get immunised simultaneously.
Dexalab Injection is not recommended for use in fungal infections. If you have any concerns, please discuss them with your doctor.
Dexalab Injection may increase the risk of Infections and infestations. Therefore, it is advised that people with chickenpox (herpes simplex), shingles (herpes zoster), or measles avoid contact.
Dexalab Injection is approved for treating coronavirus disease 2019 (COVID-19) in adults and adolescents (aged 12 years and older with a body weight of at least 40 kg) who require supplemental oxygen therapy.
Caution is advised if you are taking anticoagulants while on Dexalab Injection treatment. Checking your blood clotting time is recommended to lessen the risk of bleeding.
Dexalab Injection should not be used in patients with systemic fungal infections, allergies to dexamethasone or any other medicine ingredients, or patients who have recently received live vaccines.
Dexalab Injection may cause side effects such as depression, muscle weakness, increased sweating, increased appetite, weight gain, joint pain, irregular menstrual periods, mental health problems, impaired vision, headache, nausea, high blood pressure, heartburns, peptic ulcers, and blood clots in veins. If these side effects persist or worsen, please consult your doctor.
Dexalab Injection may interact with other medicines such as phenytoin (anticonvulsants), aspirin (nonsteroidal anti-inflammatory drugs), rifampicin (antibiotic), warfarin (anticoagulant), ritonavir (antiretroviral drugs), and aminoglutethimide (anticancer). Therefore, consult your doctor before taking other medicines while on treatment with Dexalab Injection.
Store Dexalab Injection at room temperature. Protect from light. Keep it out of reach of children.
It is essential to regularly monitor your blood sugar levels, electrolytes, blood pressure, and bone density if you are using Dexalab Injection for long-term. Discuss with doctor for any further information.
Yes, this medicine can cause fluid retention and a temporary increase in appetite, which may lead to weight gain with repeated or long-term use. Talk to your doctor if you are concerned about weight changes.
This medicine is generally only prescribed during pregnancy if the potential benefits outweigh the risks to the unborn baby. Talk to your doctor to discuss the safety of this treatment during pregnancy.
It is best to avoid alcohol, as combining it with this steroid injection can increase your risk of stomach irritation and bleeding. Talk to your doctor for personalised advice.
Stopping this medicine abruptly after regular use can cause your body's natural hormone production to crash, leading to severe fatigue, dizziness, and low blood pressure. Your doctor will guide you in gradually adjusting dose levels down safely. Talk to your doctor before making any changes.
Yes, this corticosteroid medicine can cause your blood sugar levels to rise, which is especially important to monitor if you have diabetes. Talk to your doctor about how to manage your blood sugar during treatment.
Mild pain or redness at the injection site is common and usually fades. However, if the pain worsens, or if you notice swelling, warmth, or pus, it could be a sign of infection. Talk to your doctor right away.

Disclaimer

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Country of origin

INDIA

Manufacturer/Marketer address

E-11, Industrial Area, Panipat, Haryana-132103
Other Info - DEX0116
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