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compositionComposition:DESOXIMETASONE-0.25%W/W
prescription
Prescription Medicine
info
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DEXOMET CREAM is used to treat redness, swelling and itching associated with various skin conditions. It contains Desoximetasone which works by inhibiting the release of certain chemical messengers that cause redness, itching, and swelling. In some cases, this medicine may cause side effects such as dryness, itching, irritation, or a burning sensation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DESOXIMETASONE-0.25%W/W

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About DEXOMET CREAM

DEXOMET CREAM is a high-potency topical medication prescribed to treat various inflammatory skin conditions. It works directly on the skin to reduce swelling, redness, and severe itching caused by plaque psoriasis, eczema, and other forms of dermatitis. By calming the overactive immune response in the skin cells, it helps restore comfort and healthier-looking skin.

This topical treatment is typically applied to the affected areas of the skin once or twice daily, or exactly as directed by your healthcare provider. For the best results, it should be applied consistently at the same times each day until the inflammation clears. Pairing this treatment with a gentle, fragrance-free moisturising routine and avoiding personal skin triggers can significantly improve your recovery.

While using DEXOMET CREAM, you may notice mild local reactions such as dry skin, mild burning, or temporary itching at the application site. However, if you experience more severe side effects, such as thinning skin, visible stretch marks, or signs that the medicine is being absorbed into your bloodstream—like unusual fatigue or extreme thirst—you must contact your doctor immediately.

Before starting this medication, talk to your doctor if you have a skin infection, diabetes, or a history of thinning skin. Do not use this product if you have a known allergy to any of its ingredients or if you are dealing with an untreated viral, bacterial, or fungal skin infection.

Using multiple topical steroid products at the same time can increase your risk of skin damage and systemic absorption, so always disclose your current medications to your pharmacist. It is also important to consult your healthcare provider before using this medicine if you are pregnant, planning to breastfeed, or caring for an elderly individual who may have more fragile skin.

Uses of DEXOMET CREAM

Here are the main skin conditions where DEXOMET CREAM is used to reduce inflammation, itching, and redness:

  • Psoriasis: This treatment helps flatten thick, scaly plaques on the skin and reduces the rapid buildup of skin cells.
  • Eczema (Atopic Dermatitis): It quickly targets intense itching and calms the red, irritated flare-ups characteristic of this condition.
  • Allergic Contact Dermatitis: It relieves the swelling, itching, and redness that occur when your skin reacts to an irritating substance or allergen.

Key Benefits

Using DEXOMET CREAM brings targeted relief exactly where your skin needs it most. By rapidly reducing skin inflammation, it helps you enjoy itch-free days and more restful nights, free from the discomfort of constant scratching. This allows the skin barrier to heal and recover its natural strength.

Key benefits include:

  • Rapid Itch Relief: It provides fast-acting relief from severe itching and burning sensations, helping you stay comfortable throughout the day and night.
  • Reduced Inflammation: It visibly reduces skin redness, swelling, and rough, scaly patches by calming the underlying inflammation.
  • Skin Barrier Recovery: It supports the healing of the skin barrier, helping restore a calmer and healthier skin surface.
  • Lower Risk of Secondary Infection: By reducing the urge to scratch, it helps minimise skin damage and lowers the risk of secondary skin infections.

Directions for Use

  • It is advised to take DEXOMET CREAM exactly as prescribed by your doctor, following the recommended dosage and duration to get optimal results.
  • Take a small amount of DEXOMET CREAM on the fingertip and apply it as a thin layer on the clean and dry affected area of the skin as prescribed by your doctor.
  • DEXOMET CREAM is only for external use.
  • Wash your hands before and after applying DEXOMET CREAM.
  • Please avoid contact with your eyes as it may irritate them. In case DEXOMET CREAM comes in contact with the eyes accidentally, rinse with water thoroughly.

How DEXOMET CREAM Works

DEXOMET CREAM contains desoximetasone, a topical corticosteroid that helps reduce inflammation and relieve symptoms associated with various inflammatory skin conditions. DEXOMET CREAM works by entering the skin cells and reducing the release of substances that cause inflammation. This helps decrease redness, swelling, itching, and irritation while also narrowing small blood vessels in the affected area. By calming the skin's immune response, it helps interrupt the inflammatory process and allows the skin to heal. Together, these actions help relieve itching, redness, swelling, and discomfort while promoting the healing of inflamed skin.
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Alcohol

Caution

The interaction of DEXOMET CREAM with alcohol is unknown. Please consult a doctor before consuming alcohol with DEXOMET CREAM.

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Pregnancy

Caution

DEXOMET CREAM is Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant before using DEXOMET CREAM.

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Breast Feeding

Caution

The excretion of DEXOMET CREAM in human milk is unknown and is given to a breastfeeding mother only if the doctor thinks benefits outweigh risks. However, if prescribed by a doctor, do not apply DEXOMET CREAM on breasts to prevent the baby's accidental ingestion of DEXOMET CREAM.

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Driving

Safe if prescribed

DEXOMET CREAM usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Please consult a doctor if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Please consult a doctor if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

DEXOMET CREAM should not be used in children below 18 years until and unless prescribed by a doctor as it may affect child growth and development.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using DEXOMET CREAM. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of DEXOMET CREAM in elderly patients. Please consult your doctor.

What if I have taken an overdose of DEXOMET CREAM

While an overdose from typical topical application is rare, swallowing the medication or absorbing large amounts over time can be harmful. If the medication is swallowed or if severe symptoms of systemic absorption occur, seek immediate medical attention or contact your local poison control centre.

Diet & Lifestyle Advise

  • Moisturise daily: Apply a thick, fragrance-free emollient cream or ointment within three minutes after bathing to lock in moisture and protect your skin barrier.
  • Avoid harsh soaps: Switch to mild, soap-free body washes that do not strip natural oils from your skin.
  • Identify and track triggers: Keep a daily journal of foods, fabrics, environmental factors, or stress levels that seem to provoke your skin flares.
  • Keep showers short and lukewarm: Hot water can dry out your skin and make itching worse, so opt for short, warm baths instead.
  • Wear loose, cotton clothing: Avoid tight synthetic fabrics or rough wool, which can trap 
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How Soon It Starts Working

The time required for DEXOMET CREAM to start to work: DEXOMET CREAM ideally shows its action within 1 to 3 hours after application. The time for which the effects of DEXOMET CREAM last: The effect of DEXOMET CREAM lasts for 12 to 24 hours.

What if you forget to take DEXOMET CREAM

If you forget to apply your dose, apply it as soon as you remember. If it is almost time for your next scheduled application, skip the missed dose and resume your regular routine. Do not apply double the amount to make up for a missed dose.

Storage

•Store DEXOMET CREAM at controlled room temperature, typically between 20°C and 25°C (68°F to 77° •Keep the tube or container tightly closed when not in use.

Drug Warnings

  • Only to Prescribed Areas: Only apply this medicine to the specific areas of skin prescribed by your doctor. Do not use it on your face, underarms, or groin unless explicitly directed.
  • Avoid Open or Infected Skin: Do not apply this medicine to open wounds, deep cuts, or infected skin.
  • Do Not Cover the Treated Area: Avoid using airtight dressings, plastic wraps, or tight-fitting diapers over the treated area, as this can greatly increase how much medicine your body absorbs and lead to serious side effects.
  • Do Not Share Your MedicaApply tion: Do not share this medication with anyone else, even if they have similar skin symptoms.
  • Use for the Prescribed Duration Only: Limit your use of this medicine to the exact duration prescribed by your doctor, which is typically no longer than 2 to 4 consecutive weeks.

Drug-Drug Interactions

verifiedApollotooltip

Here are the medicines and skin products that may interact with DEXOMET CREAM and increase the risk of side effects:

  • Other Corticosteroids: Combining DEXOMET CREAM with other topical corticosteroid creams or oral steroids may increase the risk of systemic absorption and side effects.
  • Irritating Skin Products: Using skin products that contain irritating or drying agents, such as alcohol, astringents, or strong peeling agents, can worsen skin irritation when used alongside this treatment.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with DEXOMET CREAM when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CORTICOSTEROIDS]

FAQs

DEXOMET CREAM is used to treat swelling, itching, and redness associated with psoriasis (scales and itchy, dry patches), dermatitis (itchy, swelling of the skin), and eczema (itchy, cracked, swollen or rough skin).
DEXOMET CREAM contains Desoximetasone, a steroid that works by inhibiting the release of certain chemical messengers (like histamine) in the body that cause redness, itching and swelling.
DEXOMET CREAM may cause a burning sensation of the skin at the application site as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor.
DEXOMET CREAM is flammable (catches fire and burns easily). Therefore, avoid smoking or going near naked flames after applying DEXOMET CREAM and avoid using DEXOMET CREAM near open flame or high heat.
You are recommended to use DEXOMET CREAM for as long as your doctor has prescribed it. However, if the symptoms persist or worsen after using DEXOMET CREAM for 2 weeks, please consult a doctor.
You are not recommended to use DEXOMET CREAM on face, groin area or underarms. However, please consult a doctor before using DEXOMET CREAM.
You are not recommended to stop using DEXOMET CREAM without consulting your doctor to worsen the condition. Therefore, use DEXOMET CREAM for as long as your doctor has prescribed it, and if you experience any difficulty while using DEXOMET CREAM, please consult your doctor.
DEXOMET CREAM may cause side effects like dryness, itching, irritation, or a burning sensation. Most of these side effects of DEXOMET CREAM do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Take a small amount of the medicine on the fingertip and apply it as a thin layer on the clean and dry affected area of the skin as prescribed by your doctor.
No, DEXOMET CREAM is not good for burns. It is used to treat redness, swelling, itching, and discomfort associated with various skin conditions.
DEXOMET CREAM starts working within a few days and you may notice an improvement in 4 weeks. Continue using DEXOMET CREAM for the prescribed duration to get the full benefits of the medicine.
DEXOMET CREAM is only for external use; do not swallow it. Avoid contact with eyes as it may irritate them. In case DEXOMET CREAM comes in contact with eyes accidentally, rinse with water thoroughly.
No, do not cover, bandage, or wrap the treated area unless your doctor has explicitly told you to do so, as covering the skin can increase the absorption of the medicine and raise your risk of side effects. Talk to your doctor.
If your skin symptoms worsen, or if you notice signs of a new infection like pus, increased pain, or warmth, stop using the medication and seek medical advice immediately. Talk to your doctor.
Topical steroids should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus, and they should not be used in large amounts or for long periods. Talk to your doctor.
No, DEXOMET CREAM is a high-potency steroid and is generally not recommended for diaper rash or for use on infants without direct specialist guidance, as diapers can act as an airtight cover and increase steroid absorption. Talk to your doctor.
Skin thinning is a recognised risk of high-potency topical steroids, especially if used for prolonged periods, on large areas, or under dressings. Talk to your doctor.
Skin thinning is a recognised risk of high-potency topical steroids, especially if used for prolonged periods, on large areas, or under dressings. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 018594S007Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Desoximetasone Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Desoximetasone Desoximetasone. 1977. [Accessed on 17 Jul. 2019]Check here
  5. Sarah Gabros, Trevor A. Nessel; Patrick M. Zito. Topical Corticosteroids. NIH National Library of Medicine, National center for biotechnology information. November 2021 [Accessed on 30th May 2022]Check here
  6. Padagis Israel Pharmaceuticals Ltd . Desoximetasone cream. DailyMed; National Library of Medicine; National Institute of Health. August 2021[Accessed on 30th May 2022] precautions id precCheck here

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - DEX0262
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