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compositionComposition:DICLOFENAC-50MG
prescription
Prescription Medicine
info
DICLONAC 50MG TABLET
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DICLOFENAC-50MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About DICLONAC 50MG TABLET

DICLONAC 50MG TABLET is a tablet primarily used to reduce pain, swelling, and joint stiffness caused by various inflammatory conditions. It helps manage symptoms of arthritis, muscle aches, and other painful bone or joint issues in adults. This medicine works by stopping the body from producing certain natural chemicals that cause inflammation.

To get the best results, you should take DICLONAC 50MG TABLET exactly as your doctor prescribes, often at regular intervals to maintain steady levels in your body. It is generally recommended to take this tablet with a glass of water, and taking it with food or milk can help protect your stomach from irritation. Alongside taking this medicine, incorporating gentle low-impact exercises and maintaining a healthy weight can significantly improve your joint mobility.

While taking DICLONAC 50MG TABLET, you may experience mild side effects like a mild upset stomach, nausea, or dizziness. However, you must contact your doctor immediately if you experience serious symptoms, such as severe stomach pain, black or tarry stools, or sudden shortness of breath.

Before starting DICLONAC 50MG TABLET, tell your doctor if you have a history of high blood pressure, heart problems, or kidney issues. Do not take this if you have an active stomach ulcer, severe heart failure, or if you have ever had an allergic reaction or asthma attack triggered by aspirin or other pain relievers.

This medicine can interact with blood thinners, blood pressure medications, and alcohol, which can increase your risk of stomach bleeding or kidney problems. If you are pregnant, planning a pregnancy, breastfeeding, or are an older adult, consult your doctor or pharmacist before taking DICLONAC 50MG TABLET. NSAID medicines such as DICLONAC 50MG TABLET may pose risks during pregnancy, particularly after 20 weeks of gestation. 

Uses of DICLONAC 50MG TABLET

DICLONAC 50MG TABLET is used to treat joint issues. The detailed uses of DICLONAC 50MG TABLET are as follows:

  • Osteoarthritis: DICLONAC 50MG TABLET relieves joint pain, swelling, and stiffness, making daily movements easier.
  • Rheumatoid arthritis: It targets chronic joint inflammation and helps reduce swelling and morning stiffness.
  • Ankylosing spondylitis: It helps manage painful inflammation in the spine, improving flexibility and comfort.
  • Acute muscle pain and gout flare-ups: It quickly reduces severe, short-term pain and inflammation in muscles and joints.
     

Key Benefits

DICLONAC 50MG TABLET provides targeted relief that helps you return to your normal daily activities. It delivers several key benefits:

  • Effective Pain Relief: It targets the source of discomfort, helping to significantly lower pain levels so you can go about your day comfortably.
  • Reduced Joint Swelling and Stiffness: By lowering inflammation, this medicine helps restore flexibility to your joints, allowing for smoother, pain-free movement and faster recovery after physical strain.
  • Improved Daily Functioning: Relief from chronic joint pain means you can participate more easily in physical therapy, work, and recreational activities, enhancing your overall quality of life.
     
Side effects of Diclonac 50mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost Vitamin K with leafy greens (spinach, kale), broccoli, cauliflower, and cabbage.
  • Include iron-rich foods like lean red meat, legumes, fortified cereals, and dark leafy greens.
  • Stay hydrated by drinking plenty of water.
  • Add Vitamin C-rich foods (citrus fruits, bell peppers) to enhance iron absorption.
  • Limit excessive alcohol and blood-thinning foods like garlic and certain herbs.
  • Engage in gentle exercise like walking, swimming, or yoga.
  • Monitor injuries and apply pressure to wounds promptly.
  • Schedule regular medical checkups for routine blood tests.

Directions for Use

To get the full benefit of DICLONAC 50MG TABLET and minimise side effects, follow these simple guidelines:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can destroy its protective coating and increase the risk of stomach irritation.
  • Take the tablet during or immediately after a meal to help prevent stomach upset.
  • Always take DICLONAC 50MG TABLET exactly as prescribed by your doctor. Do not change your dose or stop taking it without consulting them first.
     

How DICLONAC 50MG TABLET Works

DICLONAC 50MG TABLET contains diclofenac and belongs to a class of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). When your body experiences injury or joint damage, it produces natural chemicals called prostaglandins, which trigger pain, fever, and swelling. This medicine works by blocking the specific enzymes (known as COX enzymes) responsible for making these prostaglandins. By lowering the production of these chemicals in your body, DICLONAC 50MG TABLET effectively reduces both the painful sensations and the physical swelling in your joints and muscles.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with DICLONAC 50MG TABLET to avoid unpleasant side effects.

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Pregnancy

Consult your doctor

DICLONAC 50MG TABLET is not recommended during pregnancy. Please consult your doctor. Your doctor will prescribe an alternative medicine after overweighing the benefits over the risks.

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Breast Feeding

Caution

There is not enough evidence to establish the safety of DICLONAC 50MG TABLET in nursing mothers. So, it is advisable to take DICLONAC 50MG TABLET only if prescribed by your doctor.

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Driving

Unsafe

DICLONAC 50MG TABLET may cause dizziness. So avoid driving or drive only if you are alert.

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Liver

Consult your doctor

If u have or had a history of any liver-related diseases, please consult the doctor before taking DICLONAC 50MG TABLET.

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Kidney

Consult your doctor

If you have or had a history of kidney-related diseases, please consult a doctor before taking DICLONAC 50MG TABLET.

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Children

Unsafe

DICLONAC 50MG TABLET not recommended for children under 12 years of age.

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Heart

Consult your doctor

DICLONAC 50MG TABLET should be used with caution in heart patients, as it can cause an increase in the risk of side effects.

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Geriatrics

Caution

DICLONAC 50MG TABLET should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of DICLONAC 50MG TABLET

Do not take more than the prescribed dose of DICLONAC 50MG TABLET as it may cause overdose. The symptoms of overdose include stomach pain, nausea, vomiting, drowsiness, bloody/black/tarry stools, slow/shallow/irregular breathing, loss of consciousness and vomiting a substance that is bloody or looks like coffee grounds. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys filter the medication safely and efficiently.
  • Protect your stomach: Avoid consuming spicy or highly acidic foods if you experience stomach sensitivity while taking this medicine.
  • Maintain low-impact activity: Engage in gentle exercises like swimming, walking, or cycling to keep your joints flexible without putting excess stress on them.
  • Apply warm or cold compresses: Use ice packs to reduce acute joint swelling or warm compresses to soothe stiff muscles alongside your medication.
  • Watch your salt intake: If you have high blood pressure, limit your sodium intake, as NSAIDs can sometimes cause your body to retain fluids.
     

Have a query?

How Soon It Starts Working

  • The time required for DICLONAC 50MG TABLET to start to work: DICLONAC 50MG TABLET ideally shows its action within 10 to 30 minutes after administration.
  • The time for which the effects of DICLONAC 50MG TABLET last: The effect of DICLONAC 50MG TABLET lasts 8 hours.

What if you forget to take DICLONAC 50MG TABLET

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

Store DICLONAC 50MG TABLET tablets at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Always check the tablet before taking it; do not take any tablets that are cracked, chipped, or showing signs of dampness.
  • Take DICLONAC 50MG TABLET with food, milk, or an antacid if it causes mild stomach discomfort.
  • Avoid taking this medicine with other over-the-counter pain relievers (like ibuprofen or naproxen) to prevent serious stomach irritation or kidney strain.
  • Monitor your blood pressure regularly while using this medicine, as it can sometimes cause a slight increase.
  • Limit or avoid alcohol consumption while taking DICLONAC 50MG TABLET, as the combination significantly increases your risk of stomach ulcers or bleeding.
  • Use the lowest effective dose for the shortest duration needed. Long-term or high-dose use of NSAIDs such as DICLONAC 50MG TABLET may increase the risk of serious cardiovascular events, including heart attack and stroke. 
     

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Blood thinners (like warfarin): Taking these together can greatly increase the risk of serious stomach bleeding.
  • Other NSAIDs (like aspirin or ibuprofen): Combining these increases the likelihood of stomach ulcers and kidney damage.
  • Blood pressure medications (like ACE inhibitors or diuretics): DICLONAC 50MG TABLET may decrease the effectiveness of these medicines and increase the risk of kidney strain.

 

Drug-Food Interactions

  • Alcohol: Consuming alcohol while taking this medicine increases your risk of developing stomach bleeding or ulcers.

 

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking DICLONAC 50MG TABLET, as it may worsen your condition or cause complications.

  • Stomach Ulcers or Bleeding: This medication can worsen active stomach ulcers or increase the risk of recurrent gastrointestinal bleedings.
  • Kidney or Liver Disease: DICLONAC 50MG TABLET can put extra strain on these organs, potentially worsening their function.
  • Asthma: Some people with asthma may experience breathing difficulties or allergic attacks when taking this class of medication.
  • Heart Disease or High Blood Pressure: This medicine may cause fluid retention, worsen blood pressure control, and increase the risk of serious cardiovascular events such as heart attack or stroke, particularly with prolonged use or higher doses. 
     
DiclofenacMeloxicam
Critical
DiclofenacPrasugrel
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Diclonac 50mg Tablet:
Co-administration of Diclonac 50mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Diclonac 50mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacPrasugrel
Severe
How does the drug interact with Diclonac 50mg Tablet:
Taking prasugrel together with Diclonac 50mg Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Diclonac 50mg Tablet and Prasugrel can lead to an interaction; it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacVorapaxar
Severe
How does the drug interact with Diclonac 50mg Tablet:
Taking Diclonac 50mg Tablet with Vorapaxar can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Diclonac 50mg Tablet and Vorapaxar, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacTenofovir alafenamide
Severe
How does the drug interact with Diclonac 50mg Tablet:
Co-administration of Diclonac 50mg Tablet and tenofovir alafenamide may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between Diclonac 50mg Tablet and Tenofovir alafenamide but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
DiclofenacLomitapide
Severe
How does the drug interact with Diclonac 50mg Tablet:
Taking Diclonac 50mg Tablet with Lomitapide will have an additive effect and may cause liver problems.

How to manage the interaction:
There may be a possible interaction between Diclonac 50mg Tablet and Lomitapide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
DiclofenacAmiloride
Severe
How does the drug interact with Diclonac 50mg Tablet:
Taking amiloride with Diclonac 50mg Tablet can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Diclonac 50mg Tablet and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacRivaroxaban
Severe
How does the drug interact with Diclonac 50mg Tablet:
Co-administration of Rivaroxaban together with Diclonac 50mg Tablet may increase the risk of unsual bleeding.

How to manage the interaction:
Co-administration of Diclonac 50mg Tablet and Rivaroxaban can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacKetorolac
Severe
How does the drug interact with Diclonac 50mg Tablet:
Coadministration of Diclonac 50mg Tablet and Ketorolac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Co-administration of Diclonac 50mg Tablet and Ketorolac can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacKetoconazole
Severe
How does the drug interact with Diclonac 50mg Tablet:
Coadministration of Diclonac 50mg Tablet with Ketoconazole may increase the risk of liver problems.

How to manage the interaction:
There may be a possible interaction between Diclonac 50mg Tablet and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DiclofenacMipomersen
Severe
How does the drug interact with Diclonac 50mg Tablet:
Co-administration of Diclonac 50mg Tablet with Mipomersen may cause liver problems.

How to manage the interaction:
Co-administration of Diclonac 50mg Tablet and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

DICLONAC 50MG TABLET is used to relieve pain and inflammation associated with migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, gout, strain, and sprain.

DICLONAC 50MG TABLET works by blocking the effect of an enzyme called cyclo-oxygenase (COX) that produces prostaglandins responsible for the sense of pain and inflammation. Thus, it provides relief from pain and inflammation.

DICLONAC 50MG TABLET can be stopped if it is prescribed for short-term pain relief. If it has been prescribed for long-term usage, it is advised to continue as advised by your doctor.

DICLONAC 50MG TABLET may cause dizziness in some patients. Drive only if you are alert after taking DICLONAC 50MG TABLET and omit driving if you feel dizzy.

No, DICLONAC 50MG TABLET is not indicated for stomach pain. If you have symptoms of stomach pain, contact your doctor.

You may begin to feel pain relief within a few hours of taking your first dose. However, for chronic conditions like arthritis, it may take a couple of weeks of consistent use to experience the full anti-inflammatory benefits. Talk to your doctor if your symptoms do not improve.

It is best to avoid or strictly limit alcohol while taking DICLONAC 50MG TABLET. Alcohol increases the risk of stomach irritation, bleeding, and ulcers when combined with this type of pain reliever. Talk to your doctor for personalised advice.

You should avoid taking DICLONAC 50MG TABLET during pregnancy unless specifically advised by your doctor. From around 20 weeks of pregnancy onward, NSAIDs may affect the baby's kidney function and reduce amniotic fluid levels. From around 30 weeks onward (the third trimester), DICLONAC 50MG TABLET should generally be avoided because it may cause premature closure of the fetal ductus arteriosus and other serious complications. Always consult your doctor before taking this medicine during

You should not take DICLONAC 50MG TABLET with other nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, as this significantly increases the risk of stomach ulcers and kidney damage. Talk to your doctor or pharmacist before combining any pain medications.

Do not increase your dose of DICLONAC 50MG TABLET on your own. If your pain does not improve, talk to your doctor so they can evaluate your treatment plan and explore other options safely.

Yes, DICLONAC 50MG TABLET can sometimes cause fluid retention, which can lead to an increase in blood pressure. It is important to monitor your blood pressure regularly while taking this medication. Talk to your doctor if you notice any unusual readings.

Disclaimer

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Reference

  1. Drugs.com Clinical Review Team. Diclofenac Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. MedlinePlus. A689002 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  3. Diclofenac Diclofenac. 1998. [Accessed on 02 Apr. 2019] Check here
  4. Diclofenac sodium [Prescribing Information]. 2021. [Accessed on 06 Apr. 2024] Check here
  5. Cipla Limited. REACTIN® 100 SR Tablets – Product Information [Internet]. Mumbai: Cipla Limited; [Accessed on 2025 Sep 17] Check here
  6. Dexcel Pharma Ltd. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 29th July 2024] Check here
  7. Carlsbad Tech. Diclofenac sodium DR (75 mg tablets). Dailymed. [Revised in May 2016] [Accessed on 29th July 2024]Check here

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - DIC0036

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