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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Difumate-240 mg Capsule 60's is used in the treatment of multiple sclerosis, people with clinically isolated syndrome, and relapsing-remitting forms. This medicine works by stopping the body's defence system from damaging the brain and spinal cord, thereby reducing inflammation and avoiding nerve damage. Common side effects include flushing, redness, itching, rash, nausea, vomiting, diarrhoea, stomach pain, and indigestion

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Manufacturer/Marketer :

Amneal Healthcare Pvt Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Difumate-240 mg Capsule 60's

Difumate-240 mg Capsule 60's is used to treat people with clinically isolated syndrome, relapsing-remitting forms, and secondary progressive types of multiple sclerosis. Multiple sclerosis is a condition in which the immune system attacks the protective covering of the nerves (myelin) and causes disrupted communication between the brain and body.

Difumate-240 mg Capsule 60's contains Dimethyl fumarate that stops the body's defence system from damaging the brain and spinal cord. Thus, it delays the worsening of multiple sclerosis.

Difumate-240 mg Capsule 60's may cause common side effects, including flushing, redness, itching, rash, nausea, vomiting, diarrhoea, stomach pain, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

If you are allergic or sensitive to any of the components of Difumate-240 mg Capsule 60's, you should notify your doctor. Inform your doctor before taking Difumate-240 mg Capsule 60's if you have a history of a lowered immune response, severe active infection, low white blood cell counts, or liver disorders. Avoid taking Difumate-240 mg Capsule 60's if you are pregnant or breastfeeding.

Uses of Difumate-240 mg Capsule 60's

Difumate-240 mg Capsule 60's is used in the treatment of Multiple sclerosis. The detailed uses of Difumate-240 mg Capsule 60's are as follows:

  • Manage relapsing forms of multiple sclerosis: Difumate-240 mg Capsule 60's is primarily used to treat relapsing-remitting MS (RRMS) and active secondary progressive MS (SPMS). It helps reduce the frequency of relapses and slows the progression of neurological damage.
  • Modulate immune response and reduce inflammation: Difumate-240 mg Capsule 60's alters immune cell activity to decrease inflammation in the central nervous system, contributing to improved neurological function and symptom control.
  • Protect nerve cells against oxidative stress: Difumate-240 mg Capsule 60's activates the Nrf2 pathway, enhancing cellular resistance to oxidative damage and supporting long-term neural protection in MS patients.

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Directions for Use

  • Difumate-240 mg Capsule 60's can be taken with or without food, but taking it with food may help reduce side effects like flushing or stomach upset.
  • Take Difumate-240 mg Capsule 60's twice a day, preferably at the same time each day, such as morning with breakfast and evening with dinner. However, follow the dosage and timing advised by the doctor.
  • Swallow Difumate-240 mg Capsule 60's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

  • Difumate-240 mg Capsule 60's belongs to the group of medications called neuroprotective and anti-inflammatory agents.
  • This medicine is used to treat people with various forms of multiple sclerosis (MS).
  • Difumate-240 mg Capsule 60's contains Dimethyl fumarate as an active ingredient.
  • It works by reducing inflammation and preventing nerve damage, thereby effectively alleviating the symptoms of multiple sclerosis.
  • It stops the body's defence system from damaging the brain and spinal cord.

How Difumate-240 mg Capsule 60's Works

Difumate-240 mg Capsule 60's contains Dimethyl fumarate that stops the body's defence system from damaging the brain and spinal cord. Thus, it delays the worsening of multiple sclerosis. It also reduces inflammation and avoids nerve damage, thus helping treat the symptoms of multiple sclerosis.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Difumate-240 mg Capsule 60's

Do not take more than the prescribed dose of Difumate-240 mg Capsule 60's, as it may cause adverse effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • To treat your condition effectually, continue using Difumate-240 mg Capsule 60's for as long as your doctor has prescribed it.
  • It is advisable to inform the doctor if you are allergic or sensitive to its components.
  • Inform your doctor before taking Difumate-240 mg Capsule 60's if you have a history of lowered immune response, severe active infection, low white blood cell counts, and liver disorders.
  • Avoid taking Difumate-240 mg Capsule 60's if you are pregnant or breastfeeding. 
  • You must use effective contraception during treatment and for two months after stopping treatment.
  • Keep your doctor informed about your health condition and all the medicines you are taking, including vaccinations to avoid drug interactions and side effects.
  • Do not stop taking Difumate-240 mg Capsule 60's or adjust your dose without doctor notice.

Diet & Lifestyle Advise

  • Follow a well-balanced diet.
  • Exercising regularly helps in improving overall health.
  • Meditation, music and yoga have also proven very effective in helping mental health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Avoid processed and fried food.
  • Include leafy vegetables, poultry, seafood, beans, nuts, seeds, meat and fortified food in your diet.

Habit Forming

No

Therapeutic Class

[ANTI- INFLAMMATORY AGENTS]

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Alcohol

Safe if prescribed

It is unknown whether it is safe to consume alcohol with Difumate-240 mg Capsule 60's. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Consult your doctor

Do not take Difumate-240 mg Capsule 60's if you are pregnant unless prescribed by the doctor.

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Breast Feeding

Consult your doctor

Difumate-240 mg Capsule 60's is not recommended during lactation. Consult your doctor if you are breastfeeding.

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Driving

Safe if prescribed

Difumate-240 mg Capsule 60's is unlikely to influence your ability to drive and use machines. However, do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

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Liver

Consult your doctor

Difumate-240 mg Capsule 60's to be taken with caution, especially if you have a history of liver diseases/conditions. Please consult your doctor to address any concerns.

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Kidney

Consult your doctor

Difumate-240 mg Capsule 60's to be taken with caution, especially if you have a history of kidney diseases/conditions. Please consult your doctor if you have any concerns.

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Children

Safe if prescribed

Difumate-240 mg Capsule 60's should not be given to children as safety and effectiveness have not been established.

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Heart

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information is available regarding the use of Difumate-240 mg Capsule 60's in elderly patients. If you have any concerns about the usage of Difumate-240 mg Capsule 60's in geriatrics, please consult your doctor.

FAQs

Difumate-240 mg Capsule 60's is used to treat people with clinically isolated syndrome, relapsing-remitting forms, and secondary progressive types of multiple sclerosis.

Difumate-240 mg Capsule 60's stops the body's defence system from damaging the brain and spinal cord. Thereby delaying the worsening of multiple sclerosis. It also reduces inflammation and avoids nerve damage, thus helping treat the symptoms of multiple sclerosis.

Even if you feel better, keep taking Difumate-240 mg Capsule 60's for as long as your doctor has prescribed it. Do not discontinue Difumate-240 mg Capsule 60's without first consulting your doctor.

There is currently no cure for multiple sclerosis, but several treatments can help control the condition. Difumate-240 mg Capsule 60's helps lower the number of relapses and slows down the progression of physical disabilities due to multiple sclerosis.

No, Difumate-240 mg Capsule 60's is a medication prescribed by a doctor to treat specific medical conditions such as multiple sclerosis. Taking it on your own can result in adverse effects.

Elevation of liver enzymes may occur in patients receiving Difumate-240 mg Capsule 60's. Your doctor may monitor transaminase and bilirubin levels while on treatment with Difumate-240 mg Capsule 60's.

Difumate-240 mg Capsule 60's may increase the risk of infections. It is advisable to obtain a complete blood count (CBC) before initiating treatment and monitor for infection during treatment and two months after discontinuation.

Difumate-240 mg Capsule 60's may cause common side effects, including flushing, redness, itching, rash, nausea, vomiting, diarrhoea, stomach pain, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

While taking Difumate-240 mg Capsule 60's, it is important to monitor parameters like white blood cell count, liver function, kidney function, and signs of infection.

Difumate-240 mg Capsule 60's is generally not recommended for use during pregnancy and breastfeeding unless necessary. Before taking this medication, the risks and benefits should be discussed with your doctor.

There is no specific information indicating that Difumate-240 mg Capsule 60's directly affects thyroid function. However, while taking this medication, it's important to monitor your overall health and report any unusual symptoms to your healthcare provider.

Country of origin

India

Manufacturer/Marketer address

9th FLOOR, 901 To 905, ISCON ELEGANCE CIRCLE P, S.G.HIGHWAY Ahmedabad GJ 380015 IN
Other Info - DIF0072

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