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compositionComposition:NAPROXEN-500MG+SUMATRIPTAN-85MG
prescription
Prescription Medicine
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Dioset Tablet is used to prevent migraine symptoms uch as headache, nausea, and vomiting. It contains two medicines, namely Sumatriptan and Naproxen. It may cause common side effects, such as dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeats, and heartburn.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NAPROXEN-500MG+SUMATRIPTAN-85MG

Manufacturer/Marketer :

Diosma Lifesciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Dioset Tablet

Dioset Tablet is a combination prescription medicine designed to treat acute migraine attacks with or without aura in adults. It works by targeting different pathways in the body to relieve throbbing headache pain and associated symptoms like sensitivity to light and sound. This medication is not used to prevent migraines or reduce the number of attacks you have; it only treats an active migraine that has already started.

This medication is taken only when needed at the first sign of a migraine, rather than on a regular daily basis. You can take it with or without food, but taking it with food or milk may help prevent stomach upset. Managing your environment by resting in a dark, quiet room and staying hydrated can significantly improve your treatment results.

While Dioset Tablet is generally well-tolerated, some people may experience mild side effects such as dizziness, sleepiness, dry mouth, or a temporary feeling of warmth. However, you must seek medical attention immediately if you experience serious side effects like chest pressure, shortness of breath, or severe stomach pain. Always talk to your doctor or pharmacist if you notice any unusual symptoms.

Do not take this if you have a history of heart disease, uncontrolled high blood pressure, a history of stroke, or severe liver or kidney problems. It is also important to talk to your doctor or pharmacist if you have a history of stomach ulcers, bleeding disorders, or asthma before starting this medication, as it may not be safe for you.

This medicine can interact with certain antidepressants, other migraine medications, blood thinners, and alcohol, which may increase the risk of serious complications like stomach bleeding or high blood pressure. Always consult your doctor if you are pregnant, breastfeeding, or an older adult, as specific safety precautions must be taken for these groups.
 

Uses of Dioset Tablet

Dioset Tablet is used to treat acute migraine attacks with or without aura in adults. The detailed uses of Dioset Tablet are as follows:

  • Migraine headaches: Dioset Tablet is prescribed to treat active, acute migraine attacks in adults. It helps relieve severe head pain, throbbing sensations, and associated symptoms like nausea and extreme sensitivity to light and sound.

Key Benefits

Dioset Tablet helps provide effective relief from migraine attacks by targeting multiple processes involved in migraine pain. By reducing headache severity and associated symptoms, it helps you recover more quickly and return to your daily activities.

  • Helps Relieve Migraine Pain: By acting through complementary mechanisms, Dioset Tablet helps reduce the intensity of migraine headaches and associated symptoms, providing effective relief during an attack.
  • Supports Faster Recovery: By controlling migraine symptoms promptly, Dioset Tablet helps shorten the duration of an attack, allowing you to resume your normal daily routine sooner.
  • Provides Longer-Lasting Migraine Relief: By helping maintain symptom control after treatment, Dioset Tablet reduces the likelihood of headache recurrence and supports sustained relief throughout the day.
Side effects of Dioset Tablet
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • Dioset Tablet can be taken with or without food or as advised by a doctor.
  • It is advised to take Dioset Tablet exactly as prescribed by your doctor, following the recommended dosage and duration to get optimal results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Dioset Tablet Works

Dioset Tablet contains two active components that work together to stop a migraine. The first component, sumatriptan, targets specific receptors in the brain to narrow widened blood vessels and block pain pathways from sending signals to the brain. The second component, naproxen, works by stopping the production of natural inflammatory substances in the body that cause swelling, throbbing, and pain. By combining these two actions, the medication addresses both the nerve-related and inflammatory aspects of a migraine attack.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Dioset Tablet as it may cause increased drowsiness.

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Pregnancy

Caution

Dioset Tablet should be used during the first and second trimesters of pregnancy only if the benefits outweigh the risks. Dioset Tablet should not be taken during the third trimester of pregnancy.

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Breast Feeding

Caution

Dioset Tablet may pass into breastmilk and harm the baby. Please consult your doctor before taking Dioset Tablet; your doctor will decide whether Dioset Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Dioset Tablet may cause dizziness, weakness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Dioset Tablet should not be given to children as the safety and effectiveness were not established.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Unsafe

Dioset Tablet is not safe for use in elderly patients due to its serious side effects.

What if I have taken an overdose of Dioset Tablet

If you suspect an overdose or have taken more than the maximum daily limit prescribed by your doctor, seek emergency medical care immediately. Overdose symptoms may include severe stomach pain, extreme drowsiness, nausea, vomiting, or shallow breathing.

Diet & Lifestyle Advise

  • Keep a detailed migraine diary to identify and avoid food triggers, such as aged cheeses, artificial sweeteners, chocolate, processed meats, and caffeine.
  • Establish a regular sleep routine by going to bed and waking up at the same time every day, as irregular sleep cycles can trigger attacks.
  • Eat balanced meals at regular times throughout the day; skipped meals can cause blood sugar drops that trigger migraines.
  • Stay well-hydrated by drinking plenty of water daily to prevent dehydration-induced headaches.
  • Limit your intake of alcoholic beverages, which can trigger migraines and increase your risk of stomach irritation and bleeding while using this medicine.
health query

Have a query?

How Soon It Starts Working

The time required for Dioset Tablet to start to work: Dioset Tablet ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Dioset Tablet last: The duration of action for Dioset Tablet is clinically not established.

What if you forget to take Dioset Tablet

Because Dioset Tablet is taken only when needed during an active migraine attack, there is no regular daily dosing schedule to miss. If you experience an attack and have forgotten to take your medication at the start, take it as soon as you remember. Do not take a double dose if your first dose did not relieve your headache; talk to your doctor or pharmacist instead.

Storage

•Store Dioset Tablet tablets at controlled room temperature, between 20°C to 25°C (68°F to 77°F). •Keep the medicine in its original blister pack or container to protect it from moisture and direct light.

Drug Warnings

  • Take Dioset Tablet at the very first sign of a migraine to ensure the medicine works as effectively as possible.
  • Do not take any other migraine medications or daily pain relievers (like ibuprofen) within 24 hours of taking Dioset Tablet unless specifically advised by your doctor.
  • Do not use this medicine for more than 10 days in a month to avoid developing medication-overuse or rebound headaches.
  • Avoid driving or operating machinery immediately after taking this medicine, as it can cause drowsiness or dizziness.
  • Sit or lie down in a dark, quiet room after taking your dose to help speed up your recovery from the migraine.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Other migraine drugs: Taking this medicine within 24 hours of other triptan-class or ergotamine-containing migraine remedies can cause severe narrowing of blood vessels.
  • Antidepressants: Combining this medicine with certain antidepressants (like SSRIs or SNRIs) can increase the risk of a rare but serious condition called serotonin syndrome.
  • Blood thinners and other pain relievers: Combining this with aspirin, warfarin, or other daily pain relievers can significantly increase the risk of stomach ulcers and bleeding.
  • Blood pressure medicines: This medicine may make certain blood pressure drugs or water pills less effective.
     
Sumatriptan + NaproxenDihydroergotamine
Critical
Sumatriptan + NaproxenMeloxicam
Critical

Drug-Drug Interactions

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Sumatriptan + NaproxenDihydroergotamine
Critical
How does the drug interact with Dioset Tablet:
Co-administration of Dihydroergotamine with Dioset Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure.

How to manage the interaction:
Taking Dihydroergotamine with Dioset Tablet is not recommended, please consult a doctor before taking it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
Sumatriptan + NaproxenMeloxicam
Critical
How does the drug interact with Dioset Tablet:
Co-administration of Dioset Tablet with Meloxicam can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Naproxen is not advised as it can possibly result in an interaction, it can be taken if a doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not discontinue the medication without consulting a doctor.
Sumatriptan + NaproxenKetorolac
Critical
How does the drug interact with Dioset Tablet:
Co-administration of Ketorolac with Dioset Tablet can increase the risk or severity of gastric bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac with Dioset Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you notice dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Sumatriptan + NaproxenCidofovir
Critical
How does the drug interact with Dioset Tablet:
Taking Cidofovir with Dioset Tablet may increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Dioset Tablet with Cidofovir is generally avoided as it can possibly result in an interaction. You should seek immediate medical attention if you develop signs and symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
Sumatriptan + NaproxenMethylergometrine
Critical
How does the drug interact with Dioset Tablet:
Co-administration of Dioset Tablet with Methylergometrine can reduce the blood flow and increase the risk of side effects.

How to manage the interaction:
Taking Dioset Tablet with Methylergometrine together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms like severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sumatriptan + NaproxenBromocriptine
Critical
How does the drug interact with Dioset Tablet:
Co-administration of Bromocriptine with Dioset Tablet can increase the risk or severity of side effects like high blood pressure or heart-related disorders.

How to manage the interaction:
Although there is an interaction between Bromocriptine and Dioset Tablet, they can be taken together if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, consult a doctor. Do not discontinue any medication without consulting a doctor.
Sumatriptan + NaproxenIsocarboxazid
Critical
How does the drug interact with Dioset Tablet:
Combining Isocarboxazid with Dioset Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related problems.

How to manage the interaction:
Taking Isocarboxazid with Dioset Tablet is not recommended, please consult a doctor before taking it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, call a doctor. Do not discontinue any medication without consulting a doctor.
Sumatriptan + NaproxenErgotamine
Critical
How does the drug interact with Dioset Tablet:
Co-administration of Ergotamine with Dioset Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related disorders.

How to manage the interaction:
There may be a possibility of interaction between Dioset Tablet and Ergotamine, but it can be taken if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
Sumatriptan + NaproxenCelecoxib
Severe
How does the drug interact with Dioset Tablet:
Co-administration of Dioset Tablet and Celecoxib can increase the risk or severity of serious gastrointestinal toxicity (inflammation, bleeding, ulceration, and perforation).

How to manage the interaction:
Taking Dioset Tablet and Celecoxib together can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Sumatriptan + NaproxenSibutramine
Severe
How does the drug interact with Dioset Tablet:
Using Sibutramine together with Dioset Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction between Dioset Tablet and Sibutramine, you can take these medicines together if prescribed by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, call a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol while taking this medicine can increase your risk of stomach bleeding and worsen drowsiness or dizziness.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIMIGRAINE AGENTS]

FAQs

Dioset Tablet is used to prevent migraine symptoms such as headache, nausea, and vomiting.
Dioset Tablet contains Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain; this causes the narrowing of the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Naproxen works by blocking the effect of chemical messengers that cause pain.
Dry mouth could be a side-effect of Dioset Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.
Talk to your doctor before taking Dioset Tablet with anti-hypertensive medicines as they may cause impaired response when taken with painkiller. Regular monitoring of blood pressure levels is advised while taking Dioset Tablet if you have high blood pressure. Dioset Tablet should not be taken if you have uncontrolled high blood pressure.
Dioset Tablet contains painkiller, which might increase the risk of gastrointestinal adverse effects such as ulceration, bleeding, and perforation of intestines or stomach. Therefore, consult your doctor if you have stomach ulcers.
Store Dioset Tablet in its original container, keeping it cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, remove the label, place it in a plastic bag, and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.
You can stop taking Dioset Tablet once your migraine symptoms are relieved. However, always follow your doctor's instructions and consult them before stopping or adjusting the medication. If migraines persist, consult your doctor for further guidance.
Various factors, including stress, hormonal changes, certain foods, sleep disturbances, physical exertion, weather changes, and medical conditions can trigger migraines. Common triggers include chocolate, cheese, citrus fruits, bright lights, and loud noises. Identifying and managing your personal triggers can help reduce migraine frequency and severity.
The common side effects of Dioset Tablet include dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeat, and heartburn. These side effects are usually mild and temporary, resolving as your body adjusts to the medication. However, if any side effects persist or worsen, it's essential to consult your doctor for proper guidance and care.
Dioset Tablet should not be given to children as safety and effectiveness were not established.
Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches.
Taking more than the recommended dosage does not provide additional pain relief and can increase the risk of adverse effects.
No, Dioset Tablet is designed to treat an active migraine attack once it has already begun. It is not meant to be taken daily as a preventive treatment. Talk to your doctor or pharmacist about daily preventive options if you have frequent migraines.
You should consult your doctor before using Dioset Tablet if you are pregnant, planning to become pregnant, or breastfeeding. This medication may not be safe for use during pregnancy, especially in the third trimester. Talk to your doctor or pharmacist for personalised advice.
If your pain returns after initial relief, you may be able to take a second dose, but you must follow the specific time limits and daily maximum limits prescribed by your doctor. Never take more than your doctor has recommended. Talk to your doctor or pharmacist if your migraines are frequent or returning.
No, you should avoid taking Dioset Tablet with other nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or aspirin, as this can increase your risk of severe stomach irritation and bleeding. Talk to your doctor or pharmacist before combining any pain medications.
Sleepiness and dizziness are common side effects as the medicine acts on blood vessels and pathways in the brain. Avoid driving, operating machinery, or doing tasks that require alertness until you know how this medicine affects you. Talk to your doctor or pharmacist if these symptoms are severe.
It is highly recommended to avoid alcohol while taking Dioset Tablet. Alcohol can trigger or worsen migraine headaches, increase drowsiness, and significantly raise your risk of stomach bleeding. Talk to your doctor or pharmacist if you have concerns.
Using migraine relief medications like Dioset Tablet too frequently (such as more than 10 days a month) can cause your headaches to become more frequent or severe, a condition known as medication-overuse or rebound headaches. If you find yourself needing this medicine often, talk to your doctor or pharmacist about alternative treatment strategies.

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Country of origin

India

Manufacturer/Marketer address

GF 77 C WING, COMMERCIAL PREMISES, Harmony Mall, New Link Rd, Sejal Park, Colony No 1, Bhagat Singh II, Goregaon West, Mumbai, Maharashtra 400104
Other Info - DIO0184

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